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Articles 1 - 4 of 4
Full-Text Articles in Medicine and Health Sciences
Hemodynamic Changes After Aortopulmonary Separation, Ersi̇n Fadillioğlu, M. Kemal Irmak, Murat Yağmurca, Hasan Erdoğan
Hemodynamic Changes After Aortopulmonary Separation, Ersi̇n Fadillioğlu, M. Kemal Irmak, Murat Yağmurca, Hasan Erdoğan
Turkish Journal of Medical Sciences
The neural crest origin of the aortopulmonary septum has led us to investigate the septum. We designed the present study to assess the hemodynamic changes following aortopulmonary separation in the rat. We freed the ascending aorta from the pulmonary artery by blunt dissection and placed aluminium foil between them in anesthetized, ventilated, open-chest animals and found that the procedure resulted in a slight but significant increase in systolic and diastolic blood pressure and in an insignificant elevation of the heart rate. The hemodynamic deterioration observed after the separation process might be a result of a possible function of the aortopulmonary …
The Effects Of High Copper And Zinc On Some Hematological Parameters In Rats, Sebahat Aydemi̇r, Mukaddes Özcan
The Effects Of High Copper And Zinc On Some Hematological Parameters In Rats, Sebahat Aydemi̇r, Mukaddes Özcan
Turkish Journal of Veterinary & Animal Sciences
The effect of high levels of Zn and Cu supplemented into the diet on Zn and Cu levels in the liver, pancreas and serum, the number of red and white blood cells, hematocrit value, hemoglobin levels, superoxide dismutase (SOD) activity in red blood cells, live weight, and liver and pancreas weights were investigated. A total of 77 Wistar albino rats were used as the research material. Twelve of the rats were separated as the control group and the remaining 65 were divided into five experimental groups (D1, D2, D3, D4 and D5) with 13 rats in each. Then, 70 mg/kg/day …
The Reduced Effect Of Serotonin On Oxygen Consumption During Muscle Contraction In The Autoperfused Rat Hindlimb, Andrew Hoy, Gregory E. Peoples, Peter L. Mclennan
The Reduced Effect Of Serotonin On Oxygen Consumption During Muscle Contraction In The Autoperfused Rat Hindlimb, Andrew Hoy, Gregory E. Peoples, Peter L. Mclennan
Faculty of Science, Medicine and Health - Papers: part A
Serotonin (5-HT) has been shown to reduce skeletal muscle oxygen consumption cY 02) during resting conditions in a variety of animal models. It is thought to act through redistribution of blood flow within skeletal muscle directing flow away from muscle tissue (nutritive bed) towards less metabolically active tissue, adipose and septum (non-nutritive bed) by selective vasoconstriction. The aim of this study was to test whether the effects of 5-HT (previously observed under resting conditions) are reproducible during the increased metabolic demand of muscle contraction.
Histological Changes In The Rat Thoracic Aorta After Chronic Nitric Oxide Synthase Inhibition, Ni̇gar Vardi, Feral Öztürk, Ersi̇n Fadillioğlu, Ali̇ Otlu, Murat Yağmurca
Histological Changes In The Rat Thoracic Aorta After Chronic Nitric Oxide Synthase Inhibition, Ni̇gar Vardi, Feral Öztürk, Ersi̇n Fadillioğlu, Ali̇ Otlu, Murat Yağmurca
Turkish Journal of Medical Sciences
The objective of this study was to determine the morphological effects of chronic nitric oxide (NO) inhibition on the thoracic aorta of Wistar rats. Fifteen male Wistar Albino rats were divided into three groups. Group I rats (control group, n = 5) received tap water, group II rats (n = 5) recieved 100 mg/kg L-NAME (moderate NO inhibiton) and group III rats (n = 5) received 500 mg/kg L-NAME, in drinking water (severe NO inhibition) for 15 days. At the end of 15 days, the carotid arteries of the rats were cannulated and their blood pressure was measured. The rats …