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Articles 1 - 9 of 9
Full-Text Articles in Medicine and Health Sciences
Immunohistochemical Studies Of The Estrogen Receptor Alpha In The Ovaries And Uteri Of The Domestic Cat At Different Stages Of The Oestrous Cycle, Damri Darawiroj, Kongkiat Srisuwatanasagul, Sinchai Pianchop, Sayamon Sukjumlong
Immunohistochemical Studies Of The Estrogen Receptor Alpha In The Ovaries And Uteri Of The Domestic Cat At Different Stages Of The Oestrous Cycle, Damri Darawiroj, Kongkiat Srisuwatanasagul, Sinchai Pianchop, Sayamon Sukjumlong
The Thai Journal of Veterinary Medicine
The expression of the estrogen receptor alpha (ERα) was investigated in domestic cat ovaries and uteri by mean of immunohistochemistry, using monoclonal antibody against ERα. The stages of the oestrous cycle were determined by vaginal cytology and serum steroid levels which were taken before operation. In the uterus, positive staining was found in the nuclei of all uterine cell types in different proportions and staining intensity. During oestrous, the staining intensity and the proportion of positive cells were highest in the epithelium (both the surface epithelium and the glandular epithelium) as well as in the myometrium. At dioestrous, ERα expression …
First Identification Of Neospora Caninum In Thailand, Than Kyaw, Prachin Virakul, Manop Muangyai, Wijit Banlunara
First Identification Of Neospora Caninum In Thailand, Than Kyaw, Prachin Virakul, Manop Muangyai, Wijit Banlunara
The Thai Journal of Veterinary Medicine
An immunohistochemical examination of aborted bovine tissues, collected from two dairy farms that had a high abortion rate (7%), detected the organism Neospora caninum (NC). Five out of 12 aborting cows (41.7%) were seropositive to NC using a competitive ELISA test. Neospora-tachyzoites were detected in the placenta of a seropositive aborting cow. Neither NC parasites nor cysts were detected in other fetal tissues. The identification of the Neospora-parasite and a high percentage of Neospora seropositive aborting cows, suggested NC as the possible cause of abortion. This is the first identification of the NC parasite in Thailand.
The Expression Of Oestrogen And Progesterone Receptors In The Gilt Uterus At Different Stages Of The Oestrous Cycle, Sayamon Sukjumlong, Kongkiat Srisuwatanasagul, Adisorn Adirekthaworn, Kriengyot Sajjarengpong
The Expression Of Oestrogen And Progesterone Receptors In The Gilt Uterus At Different Stages Of The Oestrous Cycle, Sayamon Sukjumlong, Kongkiat Srisuwatanasagul, Adisorn Adirekthaworn, Kriengyot Sajjarengpong
The Thai Journal of Veterinary Medicine
Ovarian steroid hormones are known to be an important modulator in the regulation of reproductive function in the female. The levels of oestrogen and progesterone have been well documented whilst interacting during the entire oestrous cycle but their specific receptors in the target cells are less understood. Therefore, a comparative study of oestrogen (ER) and progesterone receptors (PR) at certain oestrous stages should be of help in the prediction of their interaction in specific uterine compartments. Tissue samples were collected at different stages of the oestrous cycle: oestrus (n=3), early dioestrus (n=3) and late dioestrus (n=3). They were fixed in …
Quantitation Of Contacts Among Sensory, Motor, And Serotonergic Neurons In The Pedal Ganglion Of Aplysia, Han Zhang, Marcy Wainwright, John H. Byrne, Leonard J. Cleary
Quantitation Of Contacts Among Sensory, Motor, And Serotonergic Neurons In The Pedal Ganglion Of Aplysia, Han Zhang, Marcy Wainwright, John H. Byrne, Leonard J. Cleary
Journal Articles
Present models of long-term sensitization in Aplysia californica indicate that the enhanced behavioral response is due, at least in part, to outgrowth of sensory neurons mediating defensive withdrawal reflexes. Presumably, this outgrowth strengthens pre-existing connections by formation of new synapses with follower neurons. However, the relationship between the number of sensorimotor contacts and the physiological strength of the connection has never been examined in intact ganglia. As a first step in addressing this issue, we used confocal microscopy to examine sites of contact between sensory and motor neurons in naive animals. Our results revealed relatively few contacts between physiologically connected …
Copper Chelation Represses The Vascular Response To Injury, Lazar Mandinov, Anna Mandinova, Stanimir Kyurkchiev, Dobroslav Kyurkchiev, Ivan Kehayov, Vihren Kolev, Raffaella Soldi, Cinzia Bagala, Ebo D. De Muinck, Volkhard Lindner, Mark J. Post, Michael Simons
Copper Chelation Represses The Vascular Response To Injury, Lazar Mandinov, Anna Mandinova, Stanimir Kyurkchiev, Dobroslav Kyurkchiev, Ivan Kehayov, Vihren Kolev, Raffaella Soldi, Cinzia Bagala, Ebo D. De Muinck, Volkhard Lindner, Mark J. Post, Michael Simons
Dartmouth Scholarship
The induction of an acute inflammatory response followed by the release of polypeptide cytokines and growth factors from peripheral blood monocytes has been implicated in mediating the response to vascular injury. Because the Cu2+-binding proteins IL-1alpha and fibroblast growth factor 1 are exported into the extracellular compartment in a stress-dependent manner by using intracellular Cu2+ to facilitate the formation of S100A13 heterotetrameric complexes and these signal peptideless polypeptides have been implicated as regulators of vascular injury in vivo, we examined the ability of Cu2+ chelation to repress neointimal thickening in response to injury. We observed that the oral administration of …
A Genetic Lesion That Arrests Plasma Cell Homing To The Bone Marrow, Loren D. Erickson, Ling-Li Lin, Biyan Duan, Laurence Morel, Randolph J. Noelle
A Genetic Lesion That Arrests Plasma Cell Homing To The Bone Marrow, Loren D. Erickson, Ling-Li Lin, Biyan Duan, Laurence Morel, Randolph J. Noelle
Dartmouth Scholarship
The coordinated regulation of chemokine responsiveness plays a critical role in the development of humoral immunity. After antigen challenge and B cell activation, the emerging plasma cells (PCs) undergo CXCL12-induced chemotaxis to the bone marrow, where they produce Ab and persist. Here we show that PCs, but not B cells or T cells from lupus-prone NZM mice, are deficient in CXCL12-induced migration. PC unresponsiveness to CXCL12 results in a marked accumulation of PCs in the spleen of mice, and a concordant decrease in bone marrow PCs. Unlike normal mice, in NZM mice, a majority of the splenic PCs are long-lived. …
Myosin Heavy Chain And Physiological Adaptation Of The Rat Diaphragm In Elastase-Induced Emphysema., Dong Kwan Kim, Jianliang Zhu, Benjamin W Kozyak, James M Burkman, Neal A Rubinstein, Edward B Lankford, Hansell H Stedman, Taitan Nguyen, Sanford Levine, Joseph B Shrager
Myosin Heavy Chain And Physiological Adaptation Of The Rat Diaphragm In Elastase-Induced Emphysema., Dong Kwan Kim, Jianliang Zhu, Benjamin W Kozyak, James M Burkman, Neal A Rubinstein, Edward B Lankford, Hansell H Stedman, Taitan Nguyen, Sanford Levine, Joseph B Shrager
Department of Pathology, Anatomy, and Cell Biology Faculty Papers
BACKGROUND: Several physiological adaptations occur in the respiratory muscles in rodent models of elastase-induced emphysema. Although the contractile properties of the diaphragm are altered in a way that suggests expression of slower isoforms of myosin heavy chain (MHC), it has been difficult to demonstrate a shift in MHCs in an animal model that corresponds to the shift toward slower MHCs seen in human emphysema. METHODS: We sought to identify MHC and corresponding physiological changes in the diaphragms of rats with elastase-induced emphysema. Nine rats with emphysema and 11 control rats were studied 10 months after instillation with elastase. MHC isoform …
Expression Of The Tumour Suppressor Gene P53 In Odontogenic Cysts, Ayla Özveren, Can Tuskan, Mehmet Yaltirik, Beli̇r Atalay, Gülçi̇n Erseven
Expression Of The Tumour Suppressor Gene P53 In Odontogenic Cysts, Ayla Özveren, Can Tuskan, Mehmet Yaltirik, Beli̇r Atalay, Gülçi̇n Erseven
Turkish Journal of Medical Sciences
The protein p53 seems to be related to the suppression of cell proliferation. Positive tissues appear to have a higher proliferative activity than negative tissues. Mutation of the p53 tumour suppressor gene has been demonstrated in a large proportion of human head and neck tumours, although no formal evidence of functional aberration has been shown p53 may have importance during the early stage of malignancy. The aim of this study was to evaluate the role of the p53 tumour suppressor gene in the pathogenesis of odontogenic cysts. Expression of abnormal p53 protein is a widely recognised marker of malignancy. Expression …
Pathological And Immunohistochemical Studies In Rabbits Experimentally Infected With Toxoplasma Gondii, Rifki Haziroğlu, Kürşat Altintaş, Ayhan Atasever, M. Yavuz Gülbahar, Oğuz Kul, Recai̇ Tunca
Pathological And Immunohistochemical Studies In Rabbits Experimentally Infected With Toxoplasma Gondii, Rifki Haziroğlu, Kürşat Altintaş, Ayhan Atasever, M. Yavuz Gülbahar, Oğuz Kul, Recai̇ Tunca
Turkish Journal of Veterinary & Animal Sciences
Experimental toxoplasmosis was induced in rabbits using different routes. A total of 42 animals were used; 36 of them were in the experimental groups and the other six comprised the control group. In addition, five guinea pigs were used for preparing hyperimmune sera against Toxoplasma gondii. The Ankara strain was inoculated intravenously (group I, n: 12), intraperitoneally (group II, n: 12) and intradermally (group III, n: 12) into the rabbits. Group IV animals were kept as controls (n: 6). Clinical and macroscopical findings varied according to the routes of inoculation and organs affected. Microscopically, multifocal necrosis with T. gondii tachyzoites …