Medicine and Health Sciences Commons^™

Effects Of Arginine Supplementation On Hemodynamics And Outcome, J. Reynolds, Jane Gervasio, G. Zaloga, L. Bortenschlager

Jane M. Gervasio

Abstract from the ASHP Midyear Clinical Meeting, New Orleans, LA, December 7-11, 2003.

Small Bowel Necrosis As A Result Of Enteral Nutrition In Critically Ill Patients, J. Reynolds, Jane Gervasio, G. Zaloga

Jane M. Gervasio

Abstract from the ASHP Midyear Clinical Meeting, New Orleans, LA, December 7-11, 2003.

Emg Remains Fractionated In Parkinson's Disease, Despite Practice-Related Improvements In Performance, D. Flament, D. Vaillancourt, T. Kempf, K. Shannon, D. Cross

Timothy Kempf

Objective: We studied the ability of patients with Parkinson's disease to improve their performance in a motor task requiring both speed and accuracy in the execution of elbow flexion movements. Our goal was to investigate the changes in electromyographic activity associated with the changes in movement performance.

Methods: Eleven patients on anti-Parkinsonian medication were tested. The patients were selected for being bradykinetic, having little or no resting tremor or dyskinesias, and being in stages II or III of the Hoehn and Yahr rating scale.

Results: The untrained patients displayed multiple bursts of agonist activity, characteristic of Parkinsonian EMG recordings. All …

Modeling The Optimum Duration Of Antibiotic Prophylaxis In An Anthrax Outbreak, Ron Brookmeyer, Elizabeth Johnson, Robert Bollinger

Ron Brookmeyer

A critical consideration in effective and measured public health responses to an outbreak of inhalational anthrax is the optimum duration of antibiotic prophylaxis. We develop a competing-risks model to address the duration of antibiotic prophylaxis and the incubation period that accounts for the risks of spore germination and spore clearance. The model predicts the incubation period distribution, which is confirmed by empirical data. The optimum duration of antibiotic prophylaxis depends critically on the dose of inhaled spores. At high doses, we show that exposed persons would need to remain on antibiotic prophylaxis for at least 4 months, and considerable morbidity …

Statistical Models And Bioterrorism: Application To The U.S. Anthrax Outbreak, Ron Brookmeyer, Natalie Blades

Ron Brookmeyer

In the fall of 2001 an outbreak of inhalational anthrax occurred in the United States that was the result of bioterrorism. Letters contaminated with anthrax spores were sent through the postal system. In response to the outbreak, public health officials treated over 10,000 persons with antibiotic prophylaxis in the hopes of preventing further morbidity and mortality. No persons receiving the antibiotics subsequently developed disease. The question arises as to how many cases of disease may actually have been prevented by the public health intervention of antibiotic prophylaxis. A statistical model is developed to answer this question by relating to the …

Quantitative And Qualitative Changes In Gene Expression Patterns Characterize The Activity Of Plaques In Multiple Sclerosis, Lotti Tajouri, Albert Mellick, Kevin Ashton, Anthony Tannenberg, Rashed Nagra, Wallace Tourtellotte, Lyn Griffiths

Lotti Tajouri

Multiple sclerosis (MS) is a complex autoimmune disorder of the CNS with both genetic and environmental contributing factors. Clinical symptoms are broadly characterized by initial onset, and progressive debilitating neurological impairment. In this study, RNA from MS chronic active and MS acute lesions was extracted, and compared with patient matched normal white matter by fluorescent cDNA microarray hybridization analysis. This resulted in the identification of 139 genes that were differentially regulated in MS plaque tissue compared to normal tissue. Of these, 69 genes showed a common pattern of expression in the chronic active and acute plaque tissues investigated (P value<0.0001, ρ=0.73, by Spearman's ρ analysis); while 70 transcripts were uniquely differentially expressed (≥1.5-fold) in either acute or chronic active tissues. These results included known markers of MS such as the myelin basic protein (MBP) and glutathione S-transferase (GST) M1, nerve growth factors, such as nerve injury-induced protein 1 (NINJ1), X-ray and excision DNA repair factors (XRCC9 and ERCC5) and X-linked genes such as the ribosomal protein, RPS4X. Primers were then designed for seven array-selected genes, including transferrin (TF), superoxide dismutase 1 (SOD1), glutathione peroxidase 1 (GPX1), GSTP1, crystallin, alpha-B (CRYAB), phosphomannomutase 1 (PMM1) and tubulin β-5 (TBB5), and real time quantitative (Q)-PCR analysis was performed. The results of comparative Q-PCR analysis correlated significantly with those obtained by array analysis (r=0.75, P value<0.01, by Pearson's bivariate correlation). Both chronic active and acute plaques shared the majority of factors identified suggesting that quantitative, rather than gross qualitative differences in gene expression pattern may define the progression from acute to chronic active plaques in MS.

Marketing Lifestyles: The Gravity Games And Generation Y., Anthony Lachowetz, G. Bennet

Anthony J Lachowetz

No abstract provided.

Critical Care Nurses Be Aware: Lemierre's Syndrome Is On The Rise, Roseanne Jane, Patricia Johnson

Patricia Johnson

Lemierre's syndrome (LS) typically occurs in previously healthy young adolescents and young adults who become acutely ill following an attack of pharyngotonsillitis. Also known as post anginal sepsis, those afflicted develop pyrexia, rigours and multiple metastatic abscesses that lead to septic thrombophlebitis of the internal jugular vein. In the pre-antibiotic era this particularly virulent syndrome had a mortality rate in excess of 90%, but since the introduction of antibiotics and the widespread treatment of throat infections, it has became almost unknown. However, due to a number of factors, including a reduction in the use of antibiotics for the treatment of …

The Efficacy Of A Work-Station Intervention Program To Improve Functional Ability And Flexibility In Ageing Clients With Cerebral Palsy: A Pilot Study, Nancy Low Choy, Rosemary Isles, Ruth Barker, Jennifer Nitz

Nancy Low Choy

Purpose:
Health care workers associated with the long-term care of ageing clients with Cerebral Palsy have reported on the adverse effects of less active daily activity programmes with resultant decreased functional mobility. While the negative effects of ageing have been reported in these clients, programmes have not been implemented to determine whether these adverse changes can be reversed or prevented. The efficacy of a work-station intervention programme to improve functional ability and flexibility in ageing clients with cerebral palsy was investigated.

Method:
A clinical intervention study using repeated measures (pre/post-intervention and at follow-up) to evaluate efficacy was undertaken. Twenty-two clients …

High-Field 19.6 T 27Al Solid-State Mas Nmr Of In Vitro Aluminated Brain Tissue, Pamela L. Bryant, Walter J. Lukiw, Zhehong Gan, Randall W. Hall, Leslie G. Butler

Randall W. Hall

Interdisciplinary Team Collaboration, Laura Greiss Hess, Kerrie Lemons, Lesley Deprey, Cynthia Winn

Laura Greiss Hess

Medial-Lateral Postural Stability And Balance In Community Dwelling Women Over 40 Years Of Age, Jennifer Nitz, Nancy Low Choy, Rosemary Isles

Nancy Low Choy

Objective:
To document the change in medial–lateral balance in women aged between 40 and 80 years.

Design:
A cross-sectional study of six measures of medial–lateral balance was undertaken.

Setting:
The Betty Byrne Henderson Centre for Women and Ageing, Royal Women's Hospital, Australia.

Subjects:
Five hundred and three community-dwelling women between 40 and 80 years of age were randomly recruited from a large metropolitan region with 366 subjects admitted after applying exclusion criteria.

Measurements:
The clinical measurements included the lateral reach and step tests while laboratory measurements were gathered from the Balance Master software programs for unilateral stance and limits of …

Assistive Technology And Augmentative Communication, Laura Greiss Hess, Kerrie Lemons

Laura Greiss Hess

Changes In Postural Stability In Women Aged 20 To 80 Years, Nancy Low Choy, Sandra Brauer, Jennifer Nitz

Nancy Low Choy

Background.
A study of postural stability was undertaken to identify the relationship between vision and support surface across age decades. Understanding when reliance on vision for postural stability emerges and the support conditions contributing to this instability may provide the evidence required to introduce falls-prevention strategies in younger age decades.

Methods.
We measured postural stability in 453 women aged 20 to 80 years using the Balance Master force-plate system while the women performed the modified Clinical Test for the Sensory Interaction and Balance (firm and foam surfaces, eyes open and closed) and the Single-Limb Stance Test (eyes open and closed). …

Exploring The Effectiveness Of Professional Sport Team's Cause-Related Sport Marketing Programs, Anthony Lachowetz, J. Gladden

Anthony J Lachowetz

No abstract provided.

The Inter Allied Games Of 1919, Don Morrow

Donald Morrow

No abstract provided.

Fluid/Electrolyte And Nutrition, Jane Gervasio

Jane M. Gervasio

No abstract provided.

Global Challenges Show, Nat Quansah

Nat Quansah

No abstract provided.

Nurse Practitioner Research: An Historical Analysis, Julie Fairman, Frances Hughes, Sean Clark, Deborah Sampson, Eileen Marx

Julie A Fairman

No abstract provided.

A Framework For Understanding Cause-Related Sport Marketing Programs, Anthony Lachowetz, J. Gladden

Anthony J Lachowetz

No abstract provided.

Business-To-Business Relationships And Sport: Using Sponsorship As A Critical Sales Event, Anthony Lachowetz, J. Clark, K. Shimmel, R. Irwin

Anthony J Lachowetz

No abstract provided.

Cause-Related Sport Sponsorship: An Assesment Of Spectator Beliefs, Attitudes, And Behavioral Intentions, Anthony Lachowetz, R. Irwin, T.B. Cornwell, J. Clark

Anthony J Lachowetz

No abstract provided.

Cause-Related Sport Marketing: How Should It Work?, Anthony Lachowetz, J. Clark, R. Irwin

Anthony J Lachowetz

No abstract provided.

Community Consent For Genetic Research, Charles Weijer

Charles Weijer

No abstract provided.

Technology And The Promise Of Independent Living For Older Adults: A Cognitive Perspective., Impact Of Technology On Successful Aging, L Liu, D Park

Linda Liu Hand

No abstract provided.

"Fundamentalism's Challenge To Modern Society", Max Skidmore

Max J. Skidmore

No abstract provided.

Assessing Brain Activity Using Spatial Bayesian Variable Selection, Michael Smith, B Putz, D Auer, Ludwig Fahrmeir

Michael Stanley Smith

Statistical parametric mapping (SPM), relying on the general linear model and classical hypothesis testing, is a benchmark tool for assessing human brain activity using data from fMRI experiments. Friston et al. (Neuroimage 16 (2002a), 484) discuss some limitations of this frequentist approach and point out promising Bayesian perspectives. In particular, a Bayesian formulation allows explicit modeling and estimation of activation probabilities. In this study, we directly address this issue and develop a new regression based approach using spatial Bayesian variable selection. Our method has several advantages. First, spatial correlation is directly modeled for activation probabilities and indirectly for activation amplitudes. …

Financial And Organizational Factors Affecting The Employment Of Nurse Practitioners And Physician Assistants In Medical Group Practices, Amer Kaissi, J Kralewski, B Dowd

Amer A Kaissi

No abstract provided.

Through The Causality Web: Looking At Etiology And Resistance In Aboriginal Cancer Experiences, Treena Orchard

Dr. Treena Orchard

No abstract provided.

"Breaking The Glass Ceiling: When (Not If) A Woman Becomes President, Max Skidmore

Max J. Skidmore

No abstract provided.