Medicine and Health Sciences Commons^™

An Empirical Study Of Marginal Structural Models For Time-Independent Treatment, Tanya A. Henneman, Mark J. Van Der Laan

U.C. Berkeley Division of Biostatistics Working Paper Series

In non-randomized treatment studies a significant problem for statisticians is determining how best to adjust for confounders. Marginal structural models (MSMs) and inverse probability of treatment weighted (IPTW) estimators are useful in analyzing the causal effect of treatment in observational studies. Given an IPTW estimator a doubly robust augmented IPTW (AIPTW) estimator orthogonalizes it resulting in a more e±cient estimator than the IPTW estimator. One purpose of this paper is to make a practical comparison between the IPTW estimator and the doubly robust AIPTW estimator via a series of Monte- Carlo simulations. We also consider the selection of the optimal …

Ada News - 10/21/2002, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Topical Micronutrient Delivery System And Uses Of Thereof, Elaine L. Jacobson, Myron Jacobson, Jaber G. Qasem, Hyuntae Kim, Moonsun Kim

Graduate Center for Nutritional Sciences Faculty Patents

The invention involves methods and compositions useful in delivering micronutrients to cells. By formulating the micronutrient in the form of an ester that is convertible to the active form of the micronutrient, one can combine it with a co-ester that inhibits esterases, so that the micronutrient can reach the targeted cells prior to degradation. Both methods and compositions are described.

Trends. Fantasies, Death, And Violence, Ibpp Editor

International Bulletin of Political Psychology

This Trends article examines violence and death in the context of the goals of international health organizations.

Regulation Of Lipoprotein Lipase By Protein Kinase Cα In 3t3-F442a Adipocytes, Gouri Ranganathan, Wei Song, Nicholas Dean, Brett Monia, Steven W. Barger, Philip A. Kern

Clinical and Translational Science Faculty Publications

Lipoprotein lipase (LPL) is an important enzyme in adipocyte and lipid metabolism with complex cellular regulation. Previous studies demonstrated an inhibition of LPL activity and synthesis following depletion of protein kinase C (PKC) isoforms with long term treatment of 3T3-F442A adipocytes with 12-O-tetradecanoylphorbol-13-acetate. To identify the specific PKC isoforms involved, we treated cells with antisense oligonucleotides that block expression of specific PKC isoforms. An antisense oligonucleotide to PKCα inhibited LPL activity by 78 ± 8%, whereas antisense oligonucleotides directed against PKCδ or PKCε had no effect on LPL activity. The change in LPL activity was maximal at 72 …

Holdcraft, Carol Interview For The Miami Valley College Of Nursing And Health Oral History Project, Donna M. Curry, Cindy Berger, Carol Holdcraft

Wright State University - Miami Valley College of Nursing and Health Oral History Project

Cindy Berger and Donna Miles Curry interviewed Carol Holdcraft about the founding of the Wright State University College of Nursing and Health. In the interview Dr. Holdcraft discusses her career and her decision to come to Wright State as faculty with the College of Nursing and Health.

Ada News - 10/07/2002, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Natural Experiment Examining Impact Of Aggressive Screening And Treatment On Prostate Cancer Mortality In Two Fixed Cohorts From Seattle Area And Connecticut, Grace Lu-Yao, Peter C. Albertsen, Janet L. Stanford, Therese A. Stukel

Dartmouth Scholarship

To determine whether the more intensive screening and treatment for prostate cancer in the Seattle≠Puget Sound area in 1987≠90 led to lower mortality from prostate cancer than in Connecticut.

Passive Transfer Of Virus-Specific Antibodies Confers Protection Against Reproductive Failure Induced By A Virulent Strain Of Porcine Reproductive And Respiratory Syndrome Virus And Establishes Sterilizing Immunity, Fernando A. Osorio, J. A. Galeota, E. Nelson, Bruce W. Brodersen, Alan R. Doster, R. Wills, F. Zuckermann, W. W. Laegried

School of Veterinary and Biomedical Sciences: Faculty Publications

Immune mechanisms mediating protective immunity against porcine reproductive and respiratory syndrome virus (PRRSV) are not well understood. The PRRSV-specific humoral immune response has been dismissed as being ineffective and perhaps deleterious for the host. The function of PRRSV antibodies in protective immunity against infection with a highly abortifacient strain of this virus was examined by passive transfer experiments in pregnant swine. All of a group of pregnant gilts (n = 6) that received PRRSV immunoglobulin (Ig) from PRRSV-convalescent, hyperimmune animals were fully protected from reproductive failure as judged by 95% viability of offspring at weaning (15 days of age). …

Healthnet News V.17:No.3 Fall 2002, Judith S. Kronick, Alberta Richetelle

Articles - Patient Care

A newsletter for public librarians and others interested in consumer health information services.

Mid-Atlantic Ethics Committee Newsletter, Fall 2002

Mid-Atlantic Ethics Committee Newsletter

No abstract provided.

Com Outlook Fall 2002, College Of Osteopathic Medicine

COM Outlook

No abstract provided.

Friendship Quality In Youth Disability Sport: Perceptions Of A Best Friend, Jeffrey J. Martin, Kerry Smith

Kinesiology, Health and Sport Studies

The purpose of the current investigation was to examine friendship quality with a best friend in youth disability sport with an international sample of moderately experienced athletes with disabilities ages 9 to 18 years. Participants were 85 males and 65 females from four countries who competed in track and field and swimming. Data were collected with the Sport Friendship Quality Scale (Weiss & Smith, 1999). An exploratory factor analyses indicated that participants viewed their friendship quality with a best friend in disability sport as having both positive and negative dimensions. The latter focused exclusively on conflict experiences. Females reported stronger …

Creating A Community Of Learners Among College Faculty Through The Use Of Reflective Practice, Cheryl M. Jorgensen, Joseph J. Onosko, Cate Weir

Institute on Disability

No abstract provided.

Dentalgram - Vol. 16, No. 10, Loma Linda University School Of Dentistry

Dentalgram

In this issue:

• Second Annual Celebration
• Brian Preston selected for ESP 2002-2003
• Orientation for new students
• School of Dentistry Fall Family Retreat
• Dr. Robert L. Frazer Jr., returns for Strategic Planning Retreat
• IDP graduation dinner
• Department news

Nurses Alumni Association Bulletin, Fall 2002, Paula Levine, Elizabeth K. Prisnock, Marian E. Smith, Sally H. Wagner, John J. Wagner

Nursing Alumni Bulletins

2002 - 2003 Meeting Date Calendar

2003 Annual Luncheon & Meeting Notice

Officers and Committee Chairs

Bulletin Publication Committee

The President's Message

Treasurer's Report

Resume of Minutes

Office News

Committee Reports

• Relief Trust Fund
• Satellite - Harrisburg Satellite Area
• Scholarship
• Social
• Nominating
• By-Laws
• Bulletin
• Development

Annual Giving Contributions

News About Graduates

Janet C. Hindson Award

Celebrating 110 Years Nursing Excellence at TJU

Memories

A Nurse 2002

A Parish - What's That

50th Anniversary Class

Class of 1952 Trolley Tour

Happy Birthday to be 80 or more

In Memoriam, Names of Deceased Graduates

Center page

Class News

Scholarship Fund Application

Certification …

Ang Ii At(1) And At(2) Receptors In Developing Kidney Of Normal Microswine, Susan P. Bagby, Linda S. Lebard, Zaiming Luo, Bryan E. Ogden, Christopher Corless, Elizabeth D. Mcpherson, Robert C. Speth

HPD Articles

To identify an appropriate model of human renin-angiotensin system (RAS) involvement in fetal origins of adult disease, we quantitated renal ANG II AT(1) and AT(2) receptors (AT1R and AT2R, respectively) in fetal (90-day gestation, n = 14), neonatal (3-wk, n = 5), and adult (6-mo, n = 8) microswine by autoradiography ((125)I-labeled [Sar(1)Ile(8)]ANG II+cold CGP-42112 for AT1R, (125)I-CGP-42112 for AT2R) and by whole kidney radioligand binding. The developmental pattern of renal AT1R in microswine, like many species, exhibited a 10-fold increase postnatally (P < 0.001), with maximal postnatal density in glomeruli and lower density AT1R in extraglomerular cortical and outer medullary sites. With aging, postnatal AT1R glomerular profiles increased in size (P < 0.001) and fractional area occupied (P < 0.04), with no change in the number per unit area. Cortical levels of AT2R by autoradiography fell with age from congruent with 5,000 fmol/g in fetal kidneys to congruent with 60 and 20% of fetal levels in neonatal and adult cortex, respectively (P < 0.0001). The pattern of AT2R binding in postnatal pig kidney mimicked that described in human and simian, but not rodent, species: dense AT2R confined to discrete cortical structures, including pre- and juxtaglomerular, but not intraglomerular, vasculature. Our results provide a quantitative assessment of ANG II receptors in developing pig kidney and document the concordance of pigs and primates in developmental regulation of renal AT1R and AT2R.

The Spectrum Of Complications Of Immunosuppression: Is The Time Right For Hand Transplantation?, Michael J. Brenner, Thomas H. Tung, John N. Jensen, Susan E. Mackinnon

Open Access Publications

No abstract provided.

Laboratory Response To Anthrax Bioterrorism, New York City, 2001, Michael B. Heller, Michel L. Bunning, Martin E.B. France, Debra M. Niemeyer, Leonard Peruski, Tim Naimi, Phillip M. Talboy, Patrick H. Murray, Harald W. Pietz, John Kornblum, William Oleszko, Sara T. Beatrice, Joint Microbiological Rapid Response Team, New York City Anthrax Investigation Working Group, Denis Nash

Publications and Research

In October 2001, the greater New York City Metropolitan Area was the scene of a bioterrorism attack. The scale of the public response to this attack was not foreseen and threatened to overwhelm the Bioterrorism Response Laboratory’s (BTRL) ability to process and test environmental samples. In a joint effort with the Centers for Disease Control and Prevention and the cooperation of the Department of Defense, a massive effort was launched to maintain and sustain the laboratory response and return test results in a timely fashion. This effort was largely successful. The development and expansion of the facility are described, as …

Synapse, Alabama Health Libraries Association

Synapse - Newsletter of ALHeLa

This is the Fall, 2002 edition of the ALHeLa newsletter - Synapse.

Contents include:

• ALHeLA Officers 2003
• Letter from Kay Hogan Smith
• NLM/AAHSL Leadership Fellows Program
• Annual Meeting
• ALHeLA Executive Committee Members (2002)
• ALHeLA Business Meeting (September 13, 2002)

A Peer-Reviewed Program For Senior Proficiencies, Cheryl Delgado, Bonnie Mack

Nursing Faculty Publications

Many nursing program require a review and retest of skilled procedures before graduation. In this way the nursing school takes steps to ensure a competent graduate practitioner. At Cleveland State University this testing is known as Senior Proficiencies, and is done in the spring semester of senior year. In the past, this has been a time-consuming task for nursing resource laboratory personnel and a stressful event for students. In their course evaluations many students expressed concern and dissatisfaction regarding their infrequently used skills and the stress associated with the retesting. The skills evaluation was a negative experience for both faculty …

Vignette - Fall 2002, University Of Alabama At Birmingham

UAB Nursing magazine

No abstract provided.

Chironian Fall/Winter 2002, New York Medical College

The Chironian

No abstract provided.

Santa Clara Magazine, Volume 44 Number 2, Fall 2002, Santa Clara University

Santa Clara Magazine

6 - INSTITUTE ON GLOBALIZATION By SCM Staff. For the academic year 2002-03, SCU will focus on globalization and how it is shaping our world.

12 - TOUGH TALK By Dale Larson. End-of-life conversations can help us cope with the loss· of a loved one.

16 - BUILDING CHARACTER By Miriam Schulman . Alumni are helping troubled kids make better choices using a program developed by SCU's Markkula Center for Applied Ethics.

The Influence Of Warning Label Presentation In Memory Recognition Of Aging Adults, Brian J. Call

Master's Theses - Daytona Beach

Research indicates that hundreds of thousands of people are injured each year as a result of poor communication between medical personnel, warning label information, and consumers when taking over the counter or prescription medication. Typically, as adults age, they are increasingly responsible for remembering the hazards of taking medications. If inadequate information exists in memory in regards to side effects, dosage, and other warnings, the likelihood of improper usage will increase. Because aging adults typically have a reduction in cognitive resources, it was hypothesized that older adults would require the aid of additional warning information to assist in the retrieval …

Development And Evaluation Of The Sleep Treatment And Education Program For Students (Steps), Franklin Christian Brown

Doctoral Dissertations

Sleep difficulties are becoming progressively more common among university students and may be related to increased academic and emotional difficulties. Psychoeducational interventions are among the most effective methods for reducing sleep difficulties and are significantly better than pharmacological treatments. Attempts to demonstrate the effectiveness of such treatments among university students are not present in the literature.

The purpose of this study was to develop the Sleep Treatment Education Program for Students (STEPS) and evaluate its effectiveness to improve sleep habits and reduce sleep complaints. The study used a double blind, experimental design. Participants in the treatment condition received Sleep Hygiene …

What's Happening: October, 2002, Maine Medical Center

What's Happening

No abstract provided.

Morbidity And Outcome Of Low Birthweight Babies Of Adolescent Mothers At Kenyatta National Hospital, Nairobi, A. Wasunna, K. Mohammed

Paediatrics and Child Health, East Africa

Objective: To compare the morbidity and outcome of low birthweight babies (birthweight < 2000gm) of adolescent (age < 20 years) and older mothers.

Design: Cross sectional descriptive study.

Setting: The newborn Unit of the Kenyatta National Hospital. Main outcome measures: All babies weighing less than 2000gm at birth whose mothers consented to the study had their gestational age verified using the Dubowitz scoring system. They were then followed up by daily clinical assessment untill discharge, death or up to one month in the ward. The babies were divided into two groups according to their mother's age and then compared with respect to episodes of illness, duration of hospital stay, and overall …

Clinical And Demographic Characteristics Of Psychiatric Inpatients Admitted Via Emergency And Non-Emergency Routes At A University Hospital In Pakistan, E U. Syed, S Mehmud, R Atiq

Department of Psychiatry

Objective: To examine the differences in the demographic and clinical characteristics of patients admitted through emergency versus non-emergency routes and see if these two groups of patients were significantly different from each other with respect to criteria mentioned in the title.Methods: Retrospective data was analysed in all 2576 patient records were reviewed and these patients were divided in two groups with respect to their mode of admission (emergency vs non emergency). These groups were then compared with respect to sex, age, length of stay, discharge status and diagnostic categories. Statistical package for social sciences version 8.0 (SPSS 8.0) was used …

Thalidomide Prevents Donor Corneal Graft Neovascularization In An Alkali Burn Model Of Corneal Angiogenesis, A. Abbas, Aga Hassan Feroze, G. F. Hyman, B. Khan

Section of Ophthalmology

Objective: Thalidomide is a potent inhibitor of angiogenesis. We evaluated the effects of Thalidomide on corneal angiogenesis and on tissue survival of grafts in rabbit eyes with pre-existing neovascularization secondary to alkali burn.
Methods: Sixteen rabbits received alkali burns to one cornea. One month post-injury, assessments of corneal neovascularization were performed followed by corneal transplantation. Four rabbits received oral Thalidomide and ten got placebo (powdered sugar) for thirty days. Total corneal neovascularization (NV), clock hours (CH) involved in (NV), longest (NV) pedicle length (NVP) and the duration of time required for NV to develop were assessed.
Results: Thalidomide significantly decreased …