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Full-Text Articles in Medicine and Health Sciences

Nicotine Enhances Acquisition Of A T-Maze Visual Discrimination: Assessment Of Individual Differences, J. Besheer, Rick A. Bevins Nov 2000

Nicotine Enhances Acquisition Of A T-Maze Visual Discrimination: Assessment Of Individual Differences, J. Besheer, Rick A. Bevins

Department of Psychology: Faculty Publications

In the present report, rats' performance was assessed in five tasks designed to measure behavioral response to different novel stimuli under different experimental situations. Daily nicotine treatment (0, 0.3 or l.0 mg/kg) began after the conclusion of the behavioral tasks and continued throughout the experiment. Training of a T-maze visual discrimination task commenced after 11 days of nicotine pretreatment. As a group, rats treated with the higher dose of nicotine (l.0 mg/kg) made fewer errors to acquire the initial T-maze discrimination than saline-treated controls. Activity induced by an inescapable novel environment (i.e. first behavioral screen) was positively correlated with the …


Quinolone Arthropathy Induced By Ofloxacin In Juvenile Rats: A Light Microscopic Study, İlki̇n Çavuşoğlu, Zeynep Kahveci̇, Semi̇ha Noyan, Zehra Mi̇nbay Jan 2000

Quinolone Arthropathy Induced By Ofloxacin In Juvenile Rats: A Light Microscopic Study, İlki̇n Çavuşoğlu, Zeynep Kahveci̇, Semi̇ha Noyan, Zehra Mi̇nbay

Turkish Journal of Medical Sciences

This study was conducted to examine the development, progression and reversibility of cartilage lesions in juvenile rats that had been given ofloxacin, a fluoroquinolone. Four-week-old rats were treated with an oral dose of 900 mg/kg/day of ofloxacin for 7 days. The animals were sacrificed at different (1 st^day, 1 st^week, 2^nd week, 4 th^ week, 8 th^ week, 12 th^ week, 16 th^ week) after the completion of the administration and the knee joints were prepared for light microscopic analysis. The lesions were demonstrated in the articular cartilage of all the animals. Acellular, oedematous matrix areas, and cavity formations were …


Epidermal Growth Factor Receptor (Egfr) Immunolocalization In The Male Rat Reproductive Tract During Pre-And Postnatal Periods, Celal Kaloğlu, Hüseyi̇n Eray Bulut, Bi̇lge Onarlioğlu Jan 2000

Epidermal Growth Factor Receptor (Egfr) Immunolocalization In The Male Rat Reproductive Tract During Pre-And Postnatal Periods, Celal Kaloğlu, Hüseyi̇n Eray Bulut, Bi̇lge Onarlioğlu

Turkish Journal of Veterinary & Animal Sciences

A number of recent studies suggest the effects of several growth factors as well as genetic factors on the development and differentiation of the testes and excretory ducts. One of the most important growth factors affecting the development and differentiation of the above-mentioned organs may be epidermal growth factor (EGF). Therefore, the aim of the present study was to investigate the effects of EGF on the development of the testes and excretory ducts of male rats by determining the immunolocalization of EGF receptors in these organs during foetal and postnatal periods. To do this, testicular and excretory duct tissue samples …