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Articles 1 - 30 of 138
Full-Text Articles in Medicine and Health Sciences
Comparison Of Inhibitory And Bactericidalactivities Of Cefoperazone + Sulbactam Againstpseudomonas Aeruginosa Strains, From 1992 To1994, Pinar Zarakolu, Ni̇lay Çöplü, Ahmet Aslantürk, Belkis Levent, Engi̇n Güvener
Comparison Of Inhibitory And Bactericidalactivities Of Cefoperazone + Sulbactam Againstpseudomonas Aeruginosa Strains, From 1992 To1994, Pinar Zarakolu, Ni̇lay Çöplü, Ahmet Aslantürk, Belkis Levent, Engi̇n Güvener
Turkish Journal of Medical Sciences
In this study; inhibitory and bactericidal activities of cefoperazone + sulbactam against Pseudomonas aeruginosa strains were determined in two studies first in 1992 and second in 1994. Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values were determined by following the microdilution method recommended by NCCLS (Approved Standard M7-A2 1990) protocol. P.aeruginosa strains were isolated from different clinical materials. The results of the studies were then compared to point out if the difference between MIC and MBC values were significant and if there was resistance development following two years of use. In the first study in 1992: MIC90 and …
Cardiovascular Disease Risk Factors In Women Working In A Tobacco Plant, Bahatti̇n Adam, Abdulkeri̇m Bedi̇r, Cumhur Kilinç, Şennur Arslan, Muhli̇se Alvur
Cardiovascular Disease Risk Factors In Women Working In A Tobacco Plant, Bahatti̇n Adam, Abdulkeri̇m Bedi̇r, Cumhur Kilinç, Şennur Arslan, Muhli̇se Alvur
Turkish Journal of Medical Sciences
To estimate the effect of exposure to tobacco dust on lipid parameters that increase the incidence of cardiovascular disease (CVD), 70 female workers were selected from the tobacco processing section of a tobacco plant, and 55 women were selected from the administration selection as the controls. The subjects were homogeneous in terms of primary and secondary risk factors such as age, alcohol intake, menstrual status, physical activity, diet, familial hyperlipidemia and heart disease. They were divided into two subgroups, smokers and nonsmokers. Venous blood and morning urine samples were simultaneously taken from workers after a 12-14 h period without food …
The Effects Of Flutamide On Lipid Profile, Insulinsensitivity, Hirsutism And Gonadotropins Inwomen With Polycystic Ovary Syndrome, Mi̇that Bahceci̇, Alpaslan Tuzcu, Mehmet Dursun, Meli̇ksah Ertem, Vahi̇t Yükselen
The Effects Of Flutamide On Lipid Profile, Insulinsensitivity, Hirsutism And Gonadotropins Inwomen With Polycystic Ovary Syndrome, Mi̇that Bahceci̇, Alpaslan Tuzcu, Mehmet Dursun, Meli̇ksah Ertem, Vahi̇t Yükselen
Turkish Journal of Medical Sciences
In this study, we evaluated metabolic changes and the effects of flutamide in 22 women with PCOS. Flutamide was administered for a 6-month period in a dose of 750 mg/day. The basal and after treatment body mass index, waist: hip ratio, blood glucose, insulin, lipids, Ferriman-Gallwey scoring (FGS), gonadotropins, testosterone, trasaminazed and glucose: insulin (G:I) ratio were measured. For comparison, ANOVA was used. The sixth month mean FGS was significantly lower than the basal values (18.5±7.4 and 12.5±4.5, P
Mao Inhibitors In Aging: Can They Serve As Protective Agents In Cardiac Tissue Against Oxidative Stress?, Ferhan Külahçioğlu Gi̇rgi̇n, Mert Özgönül, Güli̇nnaz Alper, Gülri̇z Menteş, Bi̇ltan Ersöz, Eser Yildirim Sözmen
Mao Inhibitors In Aging: Can They Serve As Protective Agents In Cardiac Tissue Against Oxidative Stress?, Ferhan Külahçioğlu Gi̇rgi̇n, Mert Özgönül, Güli̇nnaz Alper, Gülri̇z Menteş, Bi̇ltan Ersöz, Eser Yildirim Sözmen
Turkish Journal of Medical Sciences
Biological damage mediated by reactive oxygen species has been increasingly recognized in aging phenomena in recent decades. The increase in catecholamine metabolism is yet another physiological change in aging, predisposing the organism to supranormal hydrogen peroxide produc-tion as a by-product. This study was undertaken to investigate the alterations in oxidant- antioxidant status in rat cardiac tissue during aging. The effects of acute administration of monoamine oxidase (MAO) inhibitors on this status were also investigated to find possible preventive strategies in conjugate aging. MAO activities, malondialdehyde MDA and diene conjugate levels as well as superoxide dismutase and catalase activities were determined …
Quantitative Histopathology In Superficial Bladder Tumors: The Value Of Mean Nuclear Size In Progression And Recurrence, Gülsüm Özlem Elpek, Teki̇nalp Gelen, Gülten Karpuzoğlu, Osman Saka
Quantitative Histopathology In Superficial Bladder Tumors: The Value Of Mean Nuclear Size In Progression And Recurrence, Gülsüm Özlem Elpek, Teki̇nalp Gelen, Gülten Karpuzoğlu, Osman Saka
Turkish Journal of Medical Sciences
The aim of this study was to evaluate the quanititation of the nuclear size of tumor cells in superficial bladder carcinomas in progression and recurrence. Thirty-four cases diagnosed primarily as superficial bladder carcinoma grade II without muscle invasion (Stage pTa and pT1) between 1986-1993 at the Department of Pathology of Akdeniz University Faculty of Medicine were analysed in three groups: 1- Ten cases without recurrent tumor. 2- Twelve cases with primary and recurrent superficial bladder tumor. 3- Twelve cases with superficial primary tumor and recurrent tumor with muscle invasion. The mean nuclear diameter of the tumor cells were obtained by …
Rh Subgroups And Kell Antigens In Patients With Thalassemia And In Donors In Turkey, Duran Canatan, Ni̇lgün Acar, Banu Kiliç
Rh Subgroups And Kell Antigens In Patients With Thalassemia And In Donors In Turkey, Duran Canatan, Ni̇lgün Acar, Banu Kiliç
Turkish Journal of Medical Sciences
Alloimmunization can be a significant complication of transfusion therapy in patients with thalassemia and hemoglobinopathies. The aim of this study was to investigate Rh and Kell antigens in patients with thalassemia major and in donors in Turkey. A total of 3061 donors and 155 thalassemic patients from three different blood donation centers in Turkey were the subjects of this study. Antigens of Rh and Kell were determined using the Diamed Gel Test. The results of Rh haplotype tests in the thalassemic patients were 40.0% R1, 35.8% r, 19.8% R2, 2.8% R0, 1.4% r'; and in the donors were 46.7% R1, …
Effect Of Psychological Stress On Nasal Immunity, Erdal Seren, Abdülcemal Ümit Işik, Mehmet İmamoglu, Osman Bahadir, Mehmet Arif Köroğlu, Yavuz Tekeli̇oğlu
Effect Of Psychological Stress On Nasal Immunity, Erdal Seren, Abdülcemal Ümit Işik, Mehmet İmamoglu, Osman Bahadir, Mehmet Arif Köroğlu, Yavuz Tekeli̇oğlu
Turkish Journal of Medical Sciences
Stress activates the hypotalamic-pituitary- adrenal axis, increases circulating glucocorticoids, and is associated with alterations in immune functions. Nasal mucosa is richly innervated by sympathetic nerve fiber and nasal patency changes in response to various sympathetic stimuli. These fibres form close neuroeffector junctions with lymphocytes and macrophages. Nasal lavage and peripheral blood samples were collected from healthy medical students one hour before their exams and a week later, after the declaration of results of the exams were announced. We determined and compared the distribution of T lymphocyte subsets in students under psychological stress The T cell: natural killer cell, T helper …
Time Dependent Changes In The Cristaneuroepithelium Resulting From Gentamicinototoxicity In The Chinchilla, Hasan Tanyeri̇, Ivan Lopez, Larry Hoffman
Time Dependent Changes In The Cristaneuroepithelium Resulting From Gentamicinototoxicity In The Chinchilla, Hasan Tanyeri̇, Ivan Lopez, Larry Hoffman
Turkish Journal of Medical Sciences
This experiment was conducted to investigate the time-dependent effects of gentamicin (GM) on the neuroepithelial morphology of the posterior crista ampullares (PCA) of the adult chinchilla. The time course of GM-induced HC pathology was documented through measurements of HC density as well as through HC morphologic evaluation. HC morphology was examined under light microscopy and HC density measurements were documented as a function of the time course of GM-induced ototoxicity. Six groups of animals (n=12) were treated with daily injections of 30 mg/kg of GM subcutaneously (SC) for six days and were sacrificed 1, 2, 3, 4, 6 and 8 …
Effects Of Dietary Salt On Blood Pressure, Heartrate, Extracellular Fluid Volume And Glomerularfiltration Rate In Diabetic Rats, Besi̇m Özaykan, Ayşe Doğan
Effects Of Dietary Salt On Blood Pressure, Heartrate, Extracellular Fluid Volume And Glomerularfiltration Rate In Diabetic Rats, Besi̇m Özaykan, Ayşe Doğan
Turkish Journal of Medical Sciences
In the present study, we aimed to investigate the effects of dietary salt restriction and loading on extracellular fluid volume (ECFV), blood pressure (BP), heart rate (HR), glomerular filtration rate (GFR) and renal hypertrophy in diabetic rats. Diabetes was induced by injection of streptozotocin (STZ, 65 mg/kg, iv) into male Wistar rats. Four groups were formed: a) the diabetic rats given a standard rat diet (DC), b) the diabetic rats given a high-salt diet (DHS), c) the diabetic rats given a low-salt diet (DLS), d) the nondiabetic rats given a standard rat diet (C). Salt loading and salt restriction were …
The Role Of Serum Lipids On Cyclosporine-Inducedgingival Overgrowth In Renal Transplantpatients, Tunç İlgenli̇, Gül Ati̇lla, Mustafa Ci̇ri̇t, Nezi̇h Azmak
The Role Of Serum Lipids On Cyclosporine-Inducedgingival Overgrowth In Renal Transplantpatients, Tunç İlgenli̇, Gül Ati̇lla, Mustafa Ci̇ri̇t, Nezi̇h Azmak
Turkish Journal of Medical Sciences
Cyclosporine-A (CsA) is widely used to prevent organ rejection in recipients of transplanted organs and also in the treatment of various systemic diseases. CsA has a number of side effects, including gingival overgrowth (GO). However, the pathogenesis of CsA-induced GO remains uncertain. It has been postulated that CsA alters fibroblast activity. CsA is transported in plasma by binding to lipid components. It is possible that changes in serum lipid levels could alter the interaction between the CsA and gingival fibroblasts within the gingival tissues. It has also been reported that CsA may alter serum lipid levels in the transplant population. …
Clinical And Histopathological Indicators Of Neckmetastasis In Laryngeal Carcinoma, Şefi̇k Hali̇t Akmansu, Hakan Korkmaz, Engi̇n Dursun, Seli̇m Sermet Erbek, Hakan Göçmen, Tuğba Ünal, Cavi̇t Özeri̇
Clinical And Histopathological Indicators Of Neckmetastasis In Laryngeal Carcinoma, Şefi̇k Hali̇t Akmansu, Hakan Korkmaz, Engi̇n Dursun, Seli̇m Sermet Erbek, Hakan Göçmen, Tuğba Ünal, Cavi̇t Özeri̇
Turkish Journal of Medical Sciences
Determination of cervical metastasis preoperatively is very important in planning the treatment strategy in laryngeal carcinoma. In spite of vigorous clinical and detailed high technology radiological examinations, the occult metastasis rate is between 12-17% in No necks. In recent years most of the studies are related to the clinical and histopathological risk factors that may effect cervical metastasis. In this study we reviewed the primary tumors and neck specimens of laryngeal carcinoma patients operated in our clinic retrospectively. In 46 laryngeal carcinoma patients with laryngectomy and neck dissection, the following criteria were examined; Tumor localization, T status, histologic grading, peripheral …
Neutrophil Chemotaxis In Acutely Infected Andclinically Stable Cystic Fibrosis Patients, Burçi̇n Şener, Gülşen Hasçeli̇k, Uğur Özçeli̇k, Ayfer Günalp, Ayhan Göçmen
Neutrophil Chemotaxis In Acutely Infected Andclinically Stable Cystic Fibrosis Patients, Burçi̇n Şener, Gülşen Hasçeli̇k, Uğur Özçeli̇k, Ayfer Günalp, Ayhan Göçmen
Turkish Journal of Medical Sciences
Brochopulmonary infection in cystic fibrosis (CF) patients is associated with chronic progressive lung disease. The role of host factors, such as neutrophil functions, in the progressive pathologic processes in the respiratory tract of these patients, is poorly defined. Neutrophil chemotaxis is one of the first mechanisms of host defense to become activated after bacterial invasion has occurred. This study was aimed to evaluate the role of neutrophil chemotaxis in CF and also to determine whether an acute bacterial infection and the nutritional status can affect neutrophil chemotaxis or not. Twelve acutely infected and 12 clinically stable CF patients and 10 …
Very Late Relapse In Hodgkin's Disease, İmdat Di̇lek, Günhan Gürman, Işinsu Kuzu, Seli̇m Erekul
Very Late Relapse In Hodgkin's Disease, İmdat Di̇lek, Günhan Gürman, Işinsu Kuzu, Seli̇m Erekul
Turkish Journal of Medical Sciences
No abstract provided.
The Therapeutic Effect Of Nifedipine As A Ca+2entry Blocker On Experimental Transientischemic Retina, Murat Kaya, Cemal Gündoğdu
The Therapeutic Effect Of Nifedipine As A Ca+2entry Blocker On Experimental Transientischemic Retina, Murat Kaya, Cemal Gündoğdu
Turkish Journal of Medical Sciences
We evaluated the effect of nifedip-ine, an L-type voltage sensitive Ca+2 channel (VSCC) blocker, on the onset of neuronal damage induced by transient ischemia of guinea pig retinas in vivo. The animals were divided into two groups. In the first group 2 mg/kg Nifedipine was administered intraperi-toneally, while only 2 cc/kg NaCl 0.9% solution was given to the second group thirty minutes before the ischemic insult. Seven days after the temporary ligation of bilateral common carotid arteries for 45 minutes, the animals were dispatched and the eyes were enucleated for histopathologic analysis. It was observed that in the Nifedipine treated …
The Protective Effect Of Vitaminse And C On The Gastric Mucosal Barrier In Ratsirradiated With X-Rays, Ci̇hat Güzel, Cemi̇l Sert, Zeki̇ Kanay, Doğan Kurt
The Protective Effect Of Vitaminse And C On The Gastric Mucosal Barrier In Ratsirradiated With X-Rays, Ci̇hat Güzel, Cemi̇l Sert, Zeki̇ Kanay, Doğan Kurt
Turkish Journal of Medical Sciences
The protective effect of vitamins E and C on the gastric mucosal barrier in rats irradiated with X-rays was investigated. Thirty-two male Wistar Albino rats were used. The animals were divided into four groups and arranged of follows: the first group (n=8) was the sham group; the second group (n=8) was the control group which was irradiated with X-rays, the third group (n=8) to which vitamin C was administered and the fourth group (n=8) to which vitamin E was given. The animals in the groups except the sham group wereirradiated with 8.9 Gy X-rays. Twenty-four hours later, the animals were …
Percutaneous Retrieval Of Broken Port Catheterentrapped In The Right Atrium, Ahmet Memi̇ş, İsmail Oran, Vahit Özener
Percutaneous Retrieval Of Broken Port Catheterentrapped In The Right Atrium, Ahmet Memi̇ş, İsmail Oran, Vahit Özener
Turkish Journal of Medical Sciences
No abstract provided.
Spontaneous Micronuclei In Cytokinesis-Blocked Bone Marrow And Peripheral Blood Iymphocytes Of Cml Patients, Di̇lek Koç Başer, Asuman Sunguroğlu, Işik Bökesoy, Akin Uysal
Spontaneous Micronuclei In Cytokinesis-Blocked Bone Marrow And Peripheral Blood Iymphocytes Of Cml Patients, Di̇lek Koç Başer, Asuman Sunguroğlu, Işik Bökesoy, Akin Uysal
Turkish Journal of Medical Sciences
Some genetic diseases may have increased cellular instability. Since chronic myloid leukemia (CML) has a genetic base, we aimed to seek the genetic instability of patients by micronucleus analysis, a mutation screening test which was applied by cytokinesis-blocked (CB) method. In this study, 10 CML patients at diagnosis, were analysed for their micronuclei (MN) frequencies. The values were evaluated in different culture conditions of blood and bone marrow cells. The results of CML patients are compared with control' MN values obtained by peripheral blood cultures induced with PHA. Between bone marrow and peripheral blood cultures MN values with or without …
Nosocomial Uropathogens And Their Antibiotic Susceptibilities In A Turkish Military Hospital: A Prospective And Microbiological Study, Mehmet Ali̇ Saraçli, Mehmet Baysallar, Hüseyi̇n Gün
Nosocomial Uropathogens And Their Antibiotic Susceptibilities In A Turkish Military Hospital: A Prospective And Microbiological Study, Mehmet Ali̇ Saraçli, Mehmet Baysallar, Hüseyi̇n Gün
Turkish Journal of Medical Sciences
In this prospective study, we found that 21.80% (29/133) of nosocomial urinary tract infections (NUTis) were caused by Escherichia coli, 12.78% (17/133) by Pseudomonas aeruginosa and 10.53% (14/133) by Klebsiella pneumoniae whereas 16.54% (22/133) were caused by coagulase negative staphylococci. The highest susceptibility rate was determined with imipenem among gram negatives (21/28 for non-fermentatives and 65/66 for others); and with vancomycin (30/30) and pristinamycin (29/30) among gram positives. On the other hand, the lowest susceptibilities were to amoxicilin (7/66), amoxicilin clavulonat (18/66) and cotrimoxazole (27/66) among gram negatives other than non-fermentatives. All of the non-fermentative gram negative isolates were resistant …
Prevalence Of Diabetic Nephropathy In Turkish Children With Insulin-Dependent Diabetes Mellitus, Ayşenur Ökten, Gülay Kaya, Gülay Karagüzel, Yusuf Gedi̇k, Muhterem Özdemi̇r
Prevalence Of Diabetic Nephropathy In Turkish Children With Insulin-Dependent Diabetes Mellitus, Ayşenur Ökten, Gülay Kaya, Gülay Karagüzel, Yusuf Gedi̇k, Muhterem Özdemi̇r
Turkish Journal of Medical Sciences
This study was involved with determining the prevalence of diabetic nephropathy in 72 Turkish children with insulin-Dependent diabetes mellitus. Diabetic nephropathy was diagnosed with blood pressure levels, glomerular filtration rate, albumin excretion rate, ?-2 microglobulinuria and kidney length. There wereo significant differences between laboratory data for boys and girls, but adolescent patients had significantly higher albumin excretion rates than preadolescent patients (p
Psychosocial Influence Of Iddm On Children And Young Patients, Şükrü Hatun, Burhanetti̇n Kaya, Temel Yilmaz, Serpi̇l Salman, Zuhal Sağlam, Mehmet Sargin, Ahmet Şengül, Fati̇h Salman, Yücel Yilmaz
Psychosocial Influence Of Iddm On Children And Young Patients, Şükrü Hatun, Burhanetti̇n Kaya, Temel Yilmaz, Serpi̇l Salman, Zuhal Sağlam, Mehmet Sargin, Ahmet Şengül, Fati̇h Salman, Yücel Yilmaz
Turkish Journal of Medical Sciences
In this study, we evaluated 39 patients, who had been followed up in various centers, in order to determine the psychosocial effects of IDDM on children and young patients. The mean age of the patients was 15.58±2.29 years and the mean duration of diabetes was 4.41±3 years. We measured the depression and self-esteem scores in all patients using a standardized questionnaire for Turkish children. Depression was found in four patients (10.3%), and the self-esteem scores of all patients were within the normal range. There was no correlation betwenn depression or self-esteem scores and age, sex, puberty, duration of diabetes or …
Effects Of Surgical Trauma On Articular Cartilage, Di̇lek Taşkiran, Emi̇n Taşkiran, Hakan Özsoy, Veli̇ Lök
Effects Of Surgical Trauma On Articular Cartilage, Di̇lek Taşkiran, Emi̇n Taşkiran, Hakan Özsoy, Veli̇ Lök
Turkish Journal of Medical Sciences
This study was designed to evaulate the effects of reconstruction of anterior cruciate ligament on cartilage collagen and proteoglycan metabolism. Proteoglycan fragments (PF) and matrix metalloproteinase-1 (MMP-1) levels were assessed in synovial fluids aspirated from 17 patients preoperatively and at 1 st month postoperatively. Synovial fluids of 10 healthy knee served as controls. Both MMP-1 and proteoglycan fragments were found significantly elevated in pathological knees preoperatively with compare to control. The postoperative levels of MMP-1 and proteoglycans were also significantly higher than preoperative and control values. These findings suggest that surgical trauma may have detrimental effects on cartilage matrix metabolism …
The Dermatophytic Flora Ratio Of Dermatophytes, Hüseyi̇n Taniş, Gürbüz Aksoy, Zülal Aşçi
The Dermatophytic Flora Ratio Of Dermatophytes, Hüseyi̇n Taniş, Gürbüz Aksoy, Zülal Aşçi
Turkish Journal of Medical Sciences
This paper describes the mycological examination of patients admitted to the department of dermatology of Kahramanmaras State Hospital. One hundred and seventy samples of finger nails, hairs and skin were collected from patients suspected of having fungal diseases and were examined under a light microscope after being treated with 15-20% KOH solution. It was observed that 68 of the 170 samples contained fungal hyphae and arthrospores, while 62 samples were free of these. Forty samples were observed to have Malasezia furfur. The samples containing M. furfur were not subjected to a culture medium. Of the 130 cultured samples, 68 had …
A Patient With Three Simultaneously Occurring Malignancies, Bahar Kiliçarslan, Gülay Özbi̇li̇m, Gökbay Elpek, Şeyda Karaveli̇, Mi̇ne Üner
A Patient With Three Simultaneously Occurring Malignancies, Bahar Kiliçarslan, Gülay Özbi̇li̇m, Gökbay Elpek, Şeyda Karaveli̇, Mi̇ne Üner
Turkish Journal of Medical Sciences
No abstract provided.
The Evaluation Of Microanastomoses In Rats Withcolor Doppler Ultrasonography, Bahri̇ Üstünsöz, İbrahi̇m Somuncu, Mahmut Kömürcü, Mustafa Başşbozkurt, Sabri̇ Ateşalp, Alper Alemdaroğlu
The Evaluation Of Microanastomoses In Rats Withcolor Doppler Ultrasonography, Bahri̇ Üstünsöz, İbrahi̇m Somuncu, Mahmut Kömürcü, Mustafa Başşbozkurt, Sabri̇ Ateşalp, Alper Alemdaroğlu
Turkish Journal of Medical Sciences
Purpose: To evaluate the vascular patency of microanastomoses in rats with color Doppler ultrasonography. Materials and Methods: 15 superficial femoral and 15 carotid arterial end-to-end anastomoses were performed in 30 white rats. All arteries were evaluated pre- and post-operatively by color Doppler ultrasonography with a 7.5 mHz linear transducer (Acuson 128HP). All results were correlated with surgery after final Doppler evaluation. Results: The subjects were divided into three groups: (a) patent anastomosis; (b) partial occlusive anastomosis; (c) total occlusive anastomosis. The predictive value ratios for the patency group was 100% (15/15), that for the partial occlusive group was 67% (6/9) …
Prevention Of Recurrences Afterthyroidectomy In An Endemic Area Withprophylactic Levothyroxine Use, Adnan Çalik, Uzer Küçüktülü, Yavuz Bi̇lgi̇n, Aki̇f Çi̇nel, Etem Alhan, Burhan Pi̇şki̇n
Prevention Of Recurrences Afterthyroidectomy In An Endemic Area Withprophylactic Levothyroxine Use, Adnan Çalik, Uzer Küçüktülü, Yavuz Bi̇lgi̇n, Aki̇f Çi̇nel, Etem Alhan, Burhan Pi̇şki̇n
Turkish Journal of Medical Sciences
This study was planned to compare recurrence of goiters after thyroidectomy in patients who received prophylactic levothyroxine and patients who received no therapy. One hundred and twenty-six patients had been treated by bilateral subtotal thyroidectomy in the General Surgery Clinic of Karadeniz Technical University from 1987 to 1992. Eithy-eight of these patients were included in this study while the remaining patients were excluded as they were non contactable. They were divided into two groups. In group 1, there were 41 patients who had received prophylactic therapy with thyroxine 100 micro grams daily for a period of 9 to 12 months. …
Rate Of Carriage, Serotype Distribution And Penicilin Resistance Of Streptococcus Pneumoniae In Healty Children, Burçi̇n Şener, Sevtap Arikan, M. Alper Ergi̇n, Ayfer Günalp
Rate Of Carriage, Serotype Distribution And Penicilin Resistance Of Streptococcus Pneumoniae In Healty Children, Burçi̇n Şener, Sevtap Arikan, M. Alper Ergi̇n, Ayfer Günalp
Turkish Journal of Medical Sciences
The purpose of this study was to define carriage rates for Streptococcus pneumoniae in a given population in Ankara and also to determine the sertypes and penicilin resistance of these strains. Oropharyngeal swabs were taken from a total of 661 children between 1 and 11 years of age living in a province of Ankara between January 1995 and January 1997. Serotyping was performed by detection of the Quellung reaction. Penicilin susceptibilities of the isolates were screened by agar dilution method according to the guidlines of the National Committe for Clinical Laboratory Standards (NCCLS). The total rate of pneumococcal carriage in …
Decreasing Selenium Levels Andglutathione Peroxidase Activity In Patientswith Cutaneous Leishmaniasis, Abdurrahi̇m Koçyi̇ği̇t, Özcan Erel, Mehmet Sali̇h Gürel, Adnan Seyrek, Necmeddi̇n Aktepe, Selahatti̇n Gür, Senel Avci
Decreasing Selenium Levels Andglutathione Peroxidase Activity In Patientswith Cutaneous Leishmaniasis, Abdurrahi̇m Koçyi̇ği̇t, Özcan Erel, Mehmet Sali̇h Gürel, Adnan Seyrek, Necmeddi̇n Aktepe, Selahatti̇n Gür, Senel Avci
Turkish Journal of Medical Sciences
For most infectious diseases, increased formation of reactive oxygen species is secondary to the primary disease process. Some microorganisms are highly susceptible to exogenous reactive oxygen species such as hydrogen peroxide. Glutathione peroxidase (GSH-Px) remove H 2 O 2 , and selenium is requird for the activity of GSH-Px. Therefore, to assess the status of GSH-Px and selenium in cutaneous leishmaniasis (CL), we determined serum selenium concentration and blood GSH-Px activity in 52 patients with CL and in 38 healthy controls. Selenium concentrations and GSH-Px activities were found to be lower in the patient group than in the controls (p
Chromosomal Aberrations In Peripherallymphocytes Of A High-Voltage Power Linemanexposed To Electromagnetic Fields, M. Emi̇n Erdal, Nurten Erdal, Si̇bel Oğuzkan
Chromosomal Aberrations In Peripherallymphocytes Of A High-Voltage Power Linemanexposed To Electromagnetic Fields, M. Emi̇n Erdal, Nurten Erdal, Si̇bel Oğuzkan
Turkish Journal of Medical Sciences
No abstract provided.
In Vitro Effects Of Some Anthelminthics On Themalate Dehydrogenase And Lactate Dehydrogenaseenzyme Activities Of Taenia Saginata, A. Yasemi̇n Öztop, Gülendame Saygi, H. Nursevi̇n Öztop
In Vitro Effects Of Some Anthelminthics On Themalate Dehydrogenase And Lactate Dehydrogenaseenzyme Activities Of Taenia Saginata, A. Yasemi̇n Öztop, Gülendame Saygi, H. Nursevi̇n Öztop
Turkish Journal of Medical Sciences
Malate Dehydrogenase (MDH) and Lactate Dehydrogenase (LDH) activities were demonstrated in the mitochondrial and cytosolic fractions of an intestinal cestode, Taenia saginata, and then the in vitro effects of three anthelminthics, albendazole, niclosamide, and piperazine on these enzymes were investigated. The Vmax and Km values of MDH were found to be 3.00 \mumol (min mg protein) -1 and 0.0166 mM respectively. In vitro addition of albendazole and niclosamide increased the Vmax value of MDH, whereas it decreased Km value of MDH (p
Nadph-Diaphorase-Reactive Neurons In Rat Basal Ganglia, Gülgün Kayalioğlu, Fi̇gen Gövsa, Mete Ertürk
Nadph-Diaphorase-Reactive Neurons In Rat Basal Ganglia, Gülgün Kayalioğlu, Fi̇gen Gövsa, Mete Ertürk
Turkish Journal of Medical Sciences
NADPH-d reaction was performed on nine male Sprague-Dawley rats and morphometry of NADPH-d(+) cells was investigated in caudate-putamen, globus pallidus and ventral pallidum. In caudate-putamen we observed intensely stained NADPH-d (+) cells. Maximum diameter and minimum diameters of the NADPH-d (+) cells in caudate-putamen was measured as 19.19±0.04 \mum and 10.42±0.12 \mum, consequently. In globus pallidus, moderately stained NADPH-d (+) cells were observed. We measured the maximum and minimum diameters of the NADPH-d (+) cells as 19.93±0.24 \mum and 10.42±0.12 \mum, consequently. In ventral pallidum, medium-sized, moderately stained cells were present. Maximum and minimum diameters of the NADPH-d (+) cells …