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Full-Text Articles in Medicine and Health Sciences

Measurement Of Autonomic Function In Renal Disease And Diabetes, Ann King Cashion Jun 1998

Measurement Of Autonomic Function In Renal Disease And Diabetes, Ann King Cashion

Theses and Dissertations (ETD)

Renal disease and diabetes lead to dysautonomia resulting in consequences ranging from gastroparesis to sudden death. New technologies to detect dysautonomia, such as 24-hr heart rate variability, are being evaluated and compared to traditional evoked tests. These advances have, however, lead to a lack of standardization in testing batteries, procedures, and reporting formats. This series of 3 studies psychometrically assessed measures of autonomic function (AF) and explored relationships among objective and subjective measures in healthy adults and uremic patients. Participants underwent evoked tests that included change in heart rate with deep breathing and Valsalva. In addition, measures of 24-hr HRV …


Na/K-Atpase-Mediated 86rb+ Uptake And Asymmetrical Trophectoderm Localization Of Alpha1 And Alpha3 Na/K-Atpase Isoforms During Bovine Preattachment Development., D H Betts, L C Barcroft, A J Watson May 1998

Na/K-Atpase-Mediated 86rb+ Uptake And Asymmetrical Trophectoderm Localization Of Alpha1 And Alpha3 Na/K-Atpase Isoforms During Bovine Preattachment Development., D H Betts, L C Barcroft, A J Watson

Obstetrics & Gynaecology Publications

This study evaluated Na/K-ATPase alpha 1- and alpha 3-subunit isoform polypeptide expression and localization during bovine preattachment development. Na/K-ATPase cation transport activity from the one-cell to blastocyst stage was also determined by measuring ouabain-sensitive 86Rb+ uptake. Both alpha1- and alpha 3-subunit polypeptides were detected by immunofluorescence to encircle the entire cell margins of each blastomere of inseminated zygotes, cleavage stage embryos, and morulae. Immunofluorescent localization of alpha1-subunit polypeptide in bovine blastocysts revealed an alpha1 immunofluorescence signal confined to the basolateral membrane margins of the trophectoderm and encircling the cell periphery of each inner cell mass (ICM) cell. In contrast, alpha …


Urinary N-Acetyl-\Beta-D-Glucosaminidase Excretionin Asphyctic Newborns-Does It Predict Thedevelopment Of Acute Renal Failure?, Mete Aki̇sü, Nilgün Kültürsay, Resmiye Oral, Nermin Tansuğ, Caner Kabasakal Jan 1998

Urinary N-Acetyl-\Beta-D-Glucosaminidase Excretionin Asphyctic Newborns-Does It Predict Thedevelopment Of Acute Renal Failure?, Mete Aki̇sü, Nilgün Kültürsay, Resmiye Oral, Nermin Tansuğ, Caner Kabasakal

Turkish Journal of Medical Sciences

Urinary N-acetyl-\beta-D-glucosaminidase (NAG) levels of twenty healthy full-term newborns and of seventeen full-term newborns with perinatal asphyxia were evaluated within the first 48 hours of life. Urinary NAG levels and NAG indices (urinary NAG/urinary creatinine ratio) were sig-nificantly higher in newborns with perinatal asphyxia than control group (p


The Effects Of Vitamin E On Catalase Activies In Various Rat Tissues, Gülinnaz Alper, Mehtap Çinar, Cenk Can, Gülriz Menteş, Biltan Ersöz, Akgün Evinç Jan 1998

The Effects Of Vitamin E On Catalase Activies In Various Rat Tissues, Gülinnaz Alper, Mehtap Çinar, Cenk Can, Gülriz Menteş, Biltan Ersöz, Akgün Evinç

Turkish Journal of Medical Sciences

Vitamin E and other antioxidants prevent or minimize oxidative damage in biological systems. The level of antioxidant defense sufficient to protect the organism from high free radical concentrations is one of the new horizons for Vitamin E research. The role of Vitamin E as a protective agent aganist oxidative stress was evaluated by meas-uring the antioxidant enzyme catalase (CAT) activities in different tissues of Swiss male albino rats aged two months. In this study, rats were divided to three groups; control (n=10), E 1 (n=5) which received 25 mg/kg. per day of Vitamin E, IM. for 10 days and E …


Renal Ultrastructural Alterations Followingadministration Of Diethylstilbestrol, Bilge Onarlioğlu, Yasemin Günay, İsmihan Göze, Emel Koptagel Jan 1998

Renal Ultrastructural Alterations Followingadministration Of Diethylstilbestrol, Bilge Onarlioğlu, Yasemin Günay, İsmihan Göze, Emel Koptagel

Turkish Journal of Medical Sciences

Diethylstilbestrol (DES), nonsteroid in structure, is an artificial estrogen derivative and is used as an anabolic agent. It is known that diethylstilbestrol causes genetic disorders and toxic effects leading up to carcinoma even in amounts below its residual levels. For this purpose, a dose of 60µm/kg/day of DES dissolved in 0,1 ml corn oil has been administered to rats by oral gavage for varying periods of 20, 50 and 100 days periods. Rat renal tissue samples, following routine electron microscopical procedure, have been examined by transmission electron microscopy. Following diethylstilbestrol administration, glomerular capilleries seemed dilated along with occasional basement membrane …