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Articles 211 - 240 of 1145
Full-Text Articles in Medicine and Health Sciences
The Type 2 Iodothyronine Deiodinase Is Expressed Primarily In Glial Cells In The Neonatal Rat Brain, Ana Guadaño-Ferraz, Maria Jesus Obregón, Donald L. St. Germain, Juan Bernal
The Type 2 Iodothyronine Deiodinase Is Expressed Primarily In Glial Cells In The Neonatal Rat Brain, Ana Guadaño-Ferraz, Maria Jesus Obregón, Donald L. St. Germain, Juan Bernal
Dartmouth Scholarship
Thyroid hormone plays an essential role in mammalian brain maturation and function, in large part by regulating the expression of specific neuronal genes. In this tissue, the type 2 deiodinase (D2) appears to be essential for providing adequate levels of the active thyroid hormone 3,5,3′-triiodothyronine (T3) during the developmental period. We have studied the regional and cellular localization of D2 mRNA in the brain of 15-day-old neonatal rats. D2 is expressed in the cerebral cortex, olfactory bulb, hippocampus, caudate, thalamus, hypothalamus, and cerebellum and was absent from the white matter. At the cellular level, D2 is expressed predominantly, if not …
Anatomical Measurement For Localization Of Thetrue Vocal Cord In Thais, Prakobkiat Hirunwiwatkul, Patravoot Vatanasapt, Tanvaa Tansatit
Anatomical Measurement For Localization Of Thetrue Vocal Cord In Thais, Prakobkiat Hirunwiwatkul, Patravoot Vatanasapt, Tanvaa Tansatit
Chulalongkorn Medical Journal
No abstract provided.
Ultrastructure Of The May-Hegglin Anomaly, T Siddiqui
Ultrastructure Of The May-Hegglin Anomaly, T Siddiqui
Section of Internal Medicine
Ultrastructural features of the leucocytes in two patients suffering from the May-Hegglin anomaly were studied using electron microscopy. In both the cases, electron dense material parallel to the long axis of the inclusions were noted. Platelet ultrastructure was normal. A review of the literature indicates that the May-Hegglin anomaly is a heterogeneous condition both ultrastructurally and clinically.
A Novel Polymorphism Of Fcgammariiia (Cd16) Alters Receptor Function And Predisposes To Autoimmune Disease, Jianming Wu, Jeffrey C. Edberg, Patricia B. Redecha, Vipin Bansal, Paul M. Guyre, Kimberly Coleman, Jane E. Salmon, Robert P. Kimberly
A Novel Polymorphism Of Fcgammariiia (Cd16) Alters Receptor Function And Predisposes To Autoimmune Disease, Jianming Wu, Jeffrey C. Edberg, Patricia B. Redecha, Vipin Bansal, Paul M. Guyre, Kimberly Coleman, Jane E. Salmon, Robert P. Kimberly
Dartmouth Scholarship
A novel polymorphism in the extracellular domain 2 (EC2) of FcgammaRIIIA affects ligand binding by natural killer (NK) cells and monocytes from genotyped homozygous normal donors independently of receptor expression. The nonconservative T to G substitution at nucleotide 559 predicts a change of phenylalanine (F) to valine (V) at amino acid position 176. Compared with F/F homozygotes, FcgammaRIIIa expressed on NK cells and monocytes in V/V homozygotes bound more IgG1 and IgG3 despite identical levels of receptor expression. In response to a standard aggregated human IgG stimulus, FcgammaRIIIa engagement on NK cells from V/V (high-binding) homozygotes led to a larger …
Condom Availability In New York City Public High Schools: Relationships To Condom Use And Sexual Behavior, Sally Guttmacher, Lisa D. Lieberman, David Ward, Nick Freudenberg, Alice Radosh, Don Des Jarlais
Condom Availability In New York City Public High Schools: Relationships To Condom Use And Sexual Behavior, Sally Guttmacher, Lisa D. Lieberman, David Ward, Nick Freudenberg, Alice Radosh, Don Des Jarlais
Department of Public Health Scholarship and Creative Works
OBJECTIVES: This study examines the impact of the condom availability program in New York City public high schools by comparing rates of sexual activity and condom use for New York students and similar students in Chicago. METHODS: A total of 7119 students from 12 randomly selected New York schools and 5738 students from 10 Chicago schools participated in a cross-sectional survey. RESULTS: New York students, compared with Chicago students, reported equal rates of sexual activity but higher rates of condom use at last intercourse (odds ratio [OR] = 1.36). For higher-risk students (those with three or more sexual partners in …
Recommendations For Elimination Of Bovine Tuberculosis In Free-Ranging White-Tailed Deer In Michigan, K. L. Cool, James Haveman, Dan Wyant
Recommendations For Elimination Of Bovine Tuberculosis In Free-Ranging White-Tailed Deer In Michigan, K. L. Cool, James Haveman, Dan Wyant
Michigan Bovine Tuberculosis Bibliography and Database
A significant infection rate of bovine TB in the deer population of the northeastern lower peninsula poses a potential risk to several important values including public health, United States Department of Agriculture (U.S.D.A.) TB-free accreditation for Michigan cattle, wildlife health, wildlife-related recreation and tourism and economic stability in several sectors. A risk assessment study by the U.S. D.A. Centers for Epidemiology and Animal Health (Fort Collins, CO) predicted that if no changes were made in the management of the affected free-ranging deer population, the TB prevalence (compared to the current prevalence of 2.3%). Although the current annual risk of TB …
Analysis Of Bovine Herpesvirus 1 Transcripts During A Primary Infection Of Trigeminal Ganglia Of Cattle, Luis M. Schang, Clinton J. Jones
Analysis Of Bovine Herpesvirus 1 Transcripts During A Primary Infection Of Trigeminal Ganglia Of Cattle, Luis M. Schang, Clinton J. Jones
School of Veterinary and Biomedical Sciences: Faculty Publications
During an infection of nonneuronal cells, bovine herpesvirus 1 (BHV-1) gene expression proceeds in a well-defined cascade. Products of immediate-early (IE) genes are expressed first, and they activate expression of early (E) and late (L) genes. Although the same cascade is assumed to occur during an infection of neurons in trigeminal ganglia (TG) of cattle, no experimental data is available to support this hypothesis. Consequently, we analyzed BHV-1 gene expression in bovine TG at 1, 2, 4, 7, and 15 days postinfection (dpi). Infectious virus was detected in ocular swabs from 1 to 7 dpi but not 15 dpi. By …
Vol. 20 No. 3 (1997): Pacific Studies Front Matter, The Jonathan Nāpela Center For Hawaiian And Pacific Islands Studies
Vol. 20 No. 3 (1997): Pacific Studies Front Matter, The Jonathan Nāpela Center For Hawaiian And Pacific Islands Studies
Pacific Studies
Pacific Studies is published two times a year by The Jonathan Nāpela Center for Hawaiian and Pacific Studies, Brigham Young University Hawai‘i #1979, 55–220 Kulanui Street, Lāʻie, Hawai‘i 96762, but responsibility for opinions expressed in the articles rests with the authors alone. Subscription rate is US$40.00 yearly, payable to The Jonathan Nāpela Center for Hawaiian and Pacific Studies. The Jonathan Nāpela Center for Hawaiian and Pacific Studies (formerly The Pacific Institute) is an organization funded by Brigham Young University Hawai‘i. The Center assists the University in meeting its cultural and educational goals by undertaking a program of teaching, research, and …
The Place Of Persons With Disabilities In Rotuman Society, Jan Rensel, Alan Howard
The Place Of Persons With Disabilities In Rotuman Society, Jan Rensel, Alan Howard
Pacific Studies
In Rotuma, as in many other small, face-to-face societies, persons with disabilities are treated not as members of categories based on their conditions, but as individuals having whole constellations of characteristics and interpersonal histories. Their roles are not scripted on the basis of disabilities, but patterned by a number of key cultural principles that guide all relationships, including notions of immanent justice for wrongdoing, expectations of generosity and reciprocity, personal autonomy, and concern for family honor. Case studies and analyses of exchange interactions are presented to illustrate these points.
Research To Practice: Unrealized Potential: Differing Outcomes For Individuals With Mental Retardation And Other Disability Groups, Sheila Fesko
Research to Practice Series, Institute for Community Inclusion
A national study examined job search practices used by community rehabilitation providers and state vocational rehabilitation counselors. Employment outcomes for individuals with mental retardation are contrasted with those for individuals with other disabilities.
Gingival Hypertrophy In Acute Megakaryoblastic Leukemia, T Siddiqui
Gingival Hypertrophy In Acute Megakaryoblastic Leukemia, T Siddiqui
Section of Gastroenterology
No abstract provided.
Consumer Debt, Alcohol Use, And Domestic Violence In Guam, Thomas K. Pinhey, Daniel A. Lennon, Nicholas A. Pinhey
Consumer Debt, Alcohol Use, And Domestic Violence In Guam, Thomas K. Pinhey, Daniel A. Lennon, Nicholas A. Pinhey
Pacific Studies
Using community-level economic and crime data derived from secondary sources, this brief study explores the relationships between consumer debt, alcohol use, and domestic violence in Guam for the years 1982 through 1993. The results of the analysis indicate that higher levels of consumer debt are strongly related to greater alcohol consumption and domestic violence, thus suggesting that “financial strain” may be an important variable for understanding patterns of substance abuse and family violence in Guam. The implications of these results for theory and future research on substance abuse and domestic violence are also discussed.
Vol. 20 No. 3 (1997): Pacific Studies Full Issue, The Jonathan Nāpela Center For Hawaiian And Pacific Islands Studies
Vol. 20 No. 3 (1997): Pacific Studies Full Issue, The Jonathan Nāpela Center For Hawaiian And Pacific Islands Studies
Pacific Studies
Pacific Studies is published two times a year by The Jonathan Nāpela Center for Hawaiian and Pacific Studies, Brigham Young University Hawai‘i #1979, 55–220 Kulanui Street, Lāʻie, Hawai‘i 96762, but responsibility for opinions expressed in the articles rests with the authors alone. Subscription rate is US$40.00 yearly, payable to The Jonathan Nāpela Center for Hawaiian and Pacific Studies. The Jonathan Nāpela Center for Hawaiian and Pacific Studies (formerly The Pacific Institute) is an organization funded by Brigham Young University Hawai‘i. The Center assists the University in meeting its cultural and educational goals by undertaking a program of teaching, research, and …
Books Received And Book Notices, The Jonathan Nāpela Center For Hawaiian And Pacific Islands Studies
Books Received And Book Notices, The Jonathan Nāpela Center For Hawaiian And Pacific Islands Studies
Pacific Studies
Book Listing for the Vol 20, No 3 Edition of the Pacific Studies Journal
Variation In Environmental Risk Perceptions And Information Sources Among Three Communities In El Paso, Theresa L. Byrd, James Vanderslice, Susan K. Peterson
Variation In Environmental Risk Perceptions And Information Sources Among Three Communities In El Paso, Theresa L. Byrd, James Vanderslice, Susan K. Peterson
RISK: Health, Safety & Environment (1990-2002)
The authors report the results of a pilot study of environmental risk and sources of environmental information in three socio-economically and culturally distinct communities in Texas.
กุมารเวชศาสตร์ จากอดีต-ปัจจุบัน, Pakitti Tayanithi
กุมารเวชศาสตร์ จากอดีต-ปัจจุบัน, Pakitti Tayanithi
Chulalongkorn Medical Journal
No abstract provided.
Ophthalmology Today, P. Tayanithi
Laser Myopic Refractive Surgery, P. Tayanithi
Laser Myopic Refractive Surgery, P. Tayanithi
Chulalongkorn Medical Journal
No abstract provided.
The Prevalence Rates Of Human Intestinal Parasites Inmae-Ia- Moong, Umphang District, Tak Province,A Rural Area Of Thailand, Surang Triteeraprapab, Somchai Jongwutiwes, Nataros Chanthachum
The Prevalence Rates Of Human Intestinal Parasites Inmae-Ia- Moong, Umphang District, Tak Province,A Rural Area Of Thailand, Surang Triteeraprapab, Somchai Jongwutiwes, Nataros Chanthachum
Chulalongkorn Medical Journal
No abstract provided.
Superficial Pleomorphic Liposarcoma: A Case Report, Pilaiwan Kleebkaow, Shanop Shuangshoti, Voranuch Punyavoravut, Vannee Lutigaviboon
Superficial Pleomorphic Liposarcoma: A Case Report, Pilaiwan Kleebkaow, Shanop Shuangshoti, Voranuch Punyavoravut, Vannee Lutigaviboon
Chulalongkorn Medical Journal
No abstract provided.
Mri Of Hepatobiliary System, D. Boonjunwetawat
Mri Of Hepatobiliary System, D. Boonjunwetawat
Chulalongkorn Medical Journal
No abstract provided.
Sqt1, Which Encodes An Essential Wd Domain Protein Of Saccharomyces Cerevisiae, Suppresses Dominant-Negative Mutations Of The Ribosomal Protein Gene Qsr1., Dominic P. Eisinger, Frederick A. Dick, Elke Denke, Bernard L. Trumpower
Sqt1, Which Encodes An Essential Wd Domain Protein Of Saccharomyces Cerevisiae, Suppresses Dominant-Negative Mutations Of The Ribosomal Protein Gene Qsr1., Dominic P. Eisinger, Frederick A. Dick, Elke Denke, Bernard L. Trumpower
Dartmouth Scholarship
QSR1 is an essential Saccharomyces cerevisiae gene, which encodes a 60S ribosomal subunit protein required for joining of 40S and 60S subunits. Truncations of QSR1 predicted to encode C-terminally truncated forms of Qsr1p do not substitute for QSR1 but do act as dominant negative mutations, inhibiting the growth of yeast when expressed from an inducible promoter. The dominant negative mutants exhibit a polysome profile characterized by 'half-mer' polysomes, indicative of a subunit joining defect like that seen in other qsr1 mutants (D. P. Eisinger, F. A. Dick, and B. L. Trumpower, Mol. Cell. Biol. 17:5136-5145, 1997.) By screening a high-copy …
Increased Focal Adhesion Kinase- And Urokinase-Type Plasminogen Activator Receptor-Associated Cell Signaling In Endothelial Cells Exposed To Asbestos, A Barchowsky, B M. Lannon, L C. Elmore, M D. Treadwell
Increased Focal Adhesion Kinase- And Urokinase-Type Plasminogen Activator Receptor-Associated Cell Signaling In Endothelial Cells Exposed To Asbestos, A Barchowsky, B M. Lannon, L C. Elmore, M D. Treadwell
Dartmouth Scholarship
Exposure of low-passage endothelial cells in culture to nonlethal amounts of asbestos, but not refractory ceramic fiber-1, increases cell motility and gene expression. These changes may be initiated by the fibers mimicking matrix proteins as ligands for receptors on the cell surface. In the present study, 1- to 3-hr exposures of endothelial cells to 5 mg/cm2 of chrysotile asbestos caused marked cell elongation and motility. However, little morphological change was seen when chrysotile was added to cells pretreated with either mannosamine to prevent assembly of glycophosphatidylinositol (GPI)-anchored receptors or with herbimycin A to inhibit tyrosine kinase activity. Affinity purification of …
Knowledge Structures: An End To The Redundancy And The Confusion, Doreen Comerford
Knowledge Structures: An End To The Redundancy And The Confusion, Doreen Comerford
Link Foundation Modeling, Simulation and Training Fellowship Reports
Situation awareness (SA) is most commonly defined as "the perception of the elements in the environment within a volume of time and space, the comprehension of their meaning, and the projection of their status in the near future" (Endsley, 1995, p. 36). While researching this construct, we were continuously faced with several terms that, like SA, have themselves never been uniformly defined. For example, the following terms have, in some way, been associated with the construct known as SA: device model, domain model, mental model, script, schema, and "the picture" among others (c.f., Mogford, 1994; Endsley, 1995; Garland & Hopkin, …
การวิเคราะห์ปัญหา การจัดการควบคุมและการป้องกัน การสูญสียจากโรค พี อาร์ อาร์ เอส, คณิศักดิ์ อรวีระกุล
การวิเคราะห์ปัญหา การจัดการควบคุมและการป้องกัน การสูญสียจากโรค พี อาร์ อาร์ เอส, คณิศักดิ์ อรวีระกุล
The Thai Journal of Veterinary Medicine
การปรากฏของปัญหาโรค พี อาร์ อาร์ เอส ของสุกร ต้องอาศัยการวิเคราะห์และพิสูจน์ สาเหตุ ทําการประเมินสถานการณ์ที่เกิดขึ้นอย่างถูกต้อง โดยที่ปัจจัยหรือสาเหตุการสูญเสีย อาจไม่ได้เกิดจากไวรัส พี อาร์ อาร์ เอส หรืออาจเกิดร่วมกันกับสาเหตุอื่นโดยเฉพาะอย่างยิ่ง กรณีปัญหาที่เกิดขึ้นเป็นแบบเรื้อรัง แนวทางการวิเคราะห์ปัญหาประกอบด้วย การสำรวจการ สูญเสียภายในฝูง การสำรวจสถานภาพการติดเชื้อไวรัส พี อาร์ อาร์ เอส ภายในฝูง การแปลผล การตรวจทางซีรั่มวิทยา ข้อมูลดังกล่าวจะเป็นประโยชน์ในการกำหนดแนวทางแก้ไขและป้องกัน การสูญเสียที่อาจเกิดขึ้น รวมถึงการพิจารณาวัคซีนที่มีอยู่ในการควบคุมโรคดังกล่าวในประเทศไทย
หลักฐานการติดเชื้อพาร์โวไวรัสตามธรรมชาติในลูกสุนัข ช่วงอายุ 4-8 สัปดาห์, นิภัทรา เทพวัลย์, ธงชัย จันทร์ลอยเมฆ, คณิศักดิ์ อรวีระกุล, สุวิทย์ กัมทรทิพย์
หลักฐานการติดเชื้อพาร์โวไวรัสตามธรรมชาติในลูกสุนัข ช่วงอายุ 4-8 สัปดาห์, นิภัทรา เทพวัลย์, ธงชัย จันทร์ลอยเมฆ, คณิศักดิ์ อรวีระกุล, สุวิทย์ กัมทรทิพย์
The Thai Journal of Veterinary Medicine
ศึกษาหาหลักฐานการติดเชื้อพาร์โวไวรัสตามธรรมชาติในลูกสุนัขช่วงอายุ 4-8 สัปดาห์ จากแม่สุนัขซึ่งมีภูมิคุ้มกันต่อเชื้อพาร์โวไวรัสที่ศูนย์การสุนัขทหาร โดยตรวจหาแอนติเจน ในอุจจาระด้วยวิธี Hemagglutination Test และระดับแอนติบอดี้ต่อเชื้อพาร์โวไวรัสในซีรั่ม ด้วยวิธี Hemagglutination Inhibition Test จากตัวอย่างอุจจาระและซีรั่มจากลูกสุนัขจำนวน 19 ตัวที่อายุ 4, 6 และ 8 สัปดาห์ รวม 57 ตัวอย่าง ผลการศึกษาพบหลักฐานแอนติเจนที่ ตกตะกอนเม็ดเลือดแดงสุกรในอุจจาระลูกสุนัขได้อย่างน้อยตั้งแต่ที่ 4 สัปดาห์ขึ้นไปในลูกสุนัขทั้งสิ้น 89.47% (17/19) และพบการเพิ่มขึ้นของระดับแอนติบอดี้ต่อพาร์โวไวรัส ทั้งที่อายุ 6 และ 8 สัปดาห์เมื่อเทียบกับที่ 4 และ/หรือ 6 สัปดาห์เป็น 26.32% (5/19) และ 47.37% (9/19) ตามลำดับ ตลอดการศึกษาไม่พบอาการใด ๆ ที่เป็นผลจากการติดเชื้อ พาร์โวไวรัส ผลดังกล่าวแสดงถึงหลักฐานการติดเชื้อพาร์โวไวรัสตามธรรมชาติซึ่งเกิดขึ้นในลูกสุนัขที่แม่มีภูมิคุ้มกันต่อโรคพาร์โวไวรัส
Short Communication: The Isolation Of Mycobacterium Avium From A Chinese Goose (Cygnopis Cygnoides) Associated With And Epidemic Of Duck Plague In Thailand, Masaharu Kanameda, Monaya Ekgatat, Ladda Trongwongsa, Chira Kongkrong, Chaisiri Mahatachaisakul
Short Communication: The Isolation Of Mycobacterium Avium From A Chinese Goose (Cygnopis Cygnoides) Associated With And Epidemic Of Duck Plague In Thailand, Masaharu Kanameda, Monaya Ekgatat, Ladda Trongwongsa, Chira Kongkrong, Chaisiri Mahatachaisakul
The Thai Journal of Veterinary Medicine
No abstract provided.
Intimacy Deficits, Fear Of Intimacy, And Loneliness Among Sexual Offenders, Kurt M. Bumby, David J. Hansen
Intimacy Deficits, Fear Of Intimacy, And Loneliness Among Sexual Offenders, Kurt M. Bumby, David J. Hansen
Department of Psychology: Faculty Publications
Intimacy deficits and loneliness recently have been theorized as influential factors in the etiology and maintenance of sexually offending behaviors, although to date there has been a lack of empirical research conducted to address this proposition. The present study examined intimacy defi cits, fear of intimacy, and loneliness among intrafamilial child molesters, rapists, nonsexually offending inmates, and a community sample of adult males. The child molesters and rapists reported greater overall intimacy deficits than did the nonsexually offending inmates and community controls, with rapists reporting the greatest intimacy deficits. Fear of intimacy was found to be a particularly salient characteristic …
Cell Signaling Pathways Elicited By Asbestos, B T. Mossman, S Faux, Y Janssen, L A. Jimenez, Cynthia Timblin, Christine Zanella, Jonathan Goldberg, Eric Walsh, Aaron Barchowsky, Kevin Driscoll
Cell Signaling Pathways Elicited By Asbestos, B T. Mossman, S Faux, Y Janssen, L A. Jimenez, Cynthia Timblin, Christine Zanella, Jonathan Goldberg, Eric Walsh, Aaron Barchowsky, Kevin Driscoll
Dartmouth Scholarship
In recent years, it has become apparent that minerals can trigger alterations in gene expression by initiating signaling events upstream of gene transactivation. These cascades may be initiated at the cell surface after interaction of minerals with the plasma membrane either through receptorlike mechanisms or integrins. Alternatively, signaling pathways may be stimulated by active oxygen species generated both during phagocytosis of minerals and by redox reactions on the mineral surface. At least two signaling cascades linked to activation of transcription factors, i.e., DNA-binding proteins involved in modulating gene expression and DNA replication, are stimulated after exposure of lung cells to …
Qsr1p, A 60s Ribosomal Subunit Protein, Is Required For Joining Of 40s And 60s Subunits., Dominic P. Eisinger, Frederick A. Dick, Bernard L. Trumpower
Qsr1p, A 60s Ribosomal Subunit Protein, Is Required For Joining Of 40s And 60s Subunits., Dominic P. Eisinger, Frederick A. Dick, Bernard L. Trumpower
Dartmouth Scholarship
QSR1 is a recently discovered, essential Saccharomyces cerevisiae gene, which encodes a 60S ribosomal subunit protein. Thirty-one unique temperature-sensitive alleles of QSR1 were generated by regional codon randomization within a conserved 20-amino-acid sequence of the QSR1-encoded protein. The temperature-sensitive mutants arrest as viable, large, unbudded cells 24 to 48 h after a shift to 37 degrees C. Polysome and ribosomal subunit analysis by velocity gradient centrifugation of lysates from temperature-sensitive qsr1 mutants and from cells in which Qsr1p was depleted by down regulation of an inducible promoter revealed the presence of half-mer polysomes and a large pool of free 60S …