Medicine and Health Sciences Commons^™

Isolated Cataplexy: A Familial Study, Kristyna M. Hartse, Frank J. Zorick, Jeanne M. Sicklesteel, Thomas Roth

Henry Ford Hospital Medical Journal

Four members of a family, a mother, her two sons, and the mother's second cousin, presented with a history of isolated cataplexy without excessive daytime sleepiness or other symptoms typical of narcolepsy. They were polygraphically monitored during one night followed by a day of multiple nap tests. No subject manifested objective daytime sleepiness as measured by short latencies to sleep onset during daytime naps, and no subject exhibited periods of sleep onset rapid eye movement sleep in either the night or nap recordings. The incidence of isolated cataplexy in this family was traced by history through six generations. We conclude …

Front Matter

Henry Ford Hospital Medical Journal

No abstract provided.

The Expanding Spectrum Of Pediatric Practice, Jeffrey M. Devries

Henry Ford Hospital Medical Journal

No abstract provided.

Duplication And Deletion 11q23-Q24 Recombinants In Two Offspring Of An Intrachromosomal Insertion ("Shift") Carrier, Miriam G. Forsythe, Hugh Walker, Lester Weiss, Jacquelyn R. Roberson, Maria J. Worsham, V. Ramesh Babu, Daniel L. Van Dyke

Henry Ford Hospital Medical Journal

Few examples of intrachromosomal insertions have been described. These usually result from deletion of a segment of chromosome material, with insertion of the deleted material elsewhere on the same chromosome. Previous insertional translocations have been identified through a proband who has either a deletion or a duplication of the inserted segment. We describe a family which has two probands, one with a duplication and one with a deletion of the inserted segment. The unbalanced chromosomes probably resulted from an uneven number of crossovers between the breakpoints in the chromosome 11 of the father, who carries a balanced intrachromosomal insertion of …

Perinatal Idiopathic Hemochromatosis, Usha B. Raju, Sudhakar Ezhuthachan, Chan K. Ma

Henry Ford Hospital Medical Journal

We report the clinicopathologic features of an infant who died of a rare form of perinatal cirrhosis associated with idiopathic hepatic and extrahepatic parenchymal siderosis. The infant appeared normal at birth but soon became severely ill, following a progressively downhill course associated with hypoglycemia, metabolic acidosis, bleeding diathesis, jaundice, and shock. The infant died at 7 days of age. The manifestations were those of hepatic failure but mimicked sepsis and disseminated intravascular coagulation. Cirrhosis, giant cell transformation, and parenchymal iron deposition characteristic of perinatal idiopathic hemochromatosis, a recently emerging clinicopathologic entity of unknown etiology, were present in this infant. These …

Bladder Catheter Knotting: A Case Report, Mark G. Goetting

Henry Ford Hospital Medical Journal

No abstract provided.

The Development Of Pediatrics In The United States, Jay H. Mayefsky

Henry Ford Hospital Medical Journal

No abstract provided.

Serum Creatinine Concentrations In Healthy Newborns: Reference Ranges During The First Five Days Of Life, Jennie Andreson, Jaime Alfredo Zegarra, Carlos Alberto Estrada, Francis Dumler

Henry Ford Hospital Medical Journal

Serum creatinine concentrations were studied in 52 healthy, full-term infants (29 males and 23 females) during the first five days of life. At birth, mean serum creatinine concentration was 0.76 ± 0.13 mg/dL. At 6 hours of life, values increased to 0.97 ± 0.11 mg/dL (P < 0.001) and remained elevated for 24 hours. Values then returned to baseline so that serum creatinine concentrations were 0.81 ± 0.15 mg/dL at 48 hours and 0.6l ± 0.15 mg/dL at 3 to 5 days of age. At birth, serum creatinine concentrations were higher in males than in females (0.80 ± 0.13 versus 0.71 ± 0.11 mg/dL, respectively; P < 0.009). However, the increases in serum creatinine concentration observed after birth were similar in both sexes. This is the first report of a prospective longitudinal study of serum creatinine concentrations between birth and 3 to 5 days of age in a Hispanic population. In addition, data were analyzed by sex. The results are a useful reference for normal serum creatinine concentrations in early life.

Ovarian Failure In A Chromosomally Competent Adolescent Female: A Case Report, T. Jann Caison-Sorey

Henry Ford Hospital Medical Journal

Primary ovarian failure in adolescence is uncommon. This report depicts such a case in a 17 1/2-year old girl whose investigation revealed elevations in the follicle-stimulating hormone and luteinizing hormone levels in association with a low estrogen level. The blood leukocyte chromosome analysis with Giemsa banding revealed a 46,XX chromosomal complement. Pelvic ultrasound disclosed a rudimentary uterus and a small left ovary. Hormonal replacement has resulted in advancement of secondary sexual characteristics and monthly withdrawal bleeding.

Validation Of Electronic Rectal Thermometry, Mark G. Goetting, Karen Stratton

Henry Ford Hospital Medical Journal

Electronic rectal thermometry is performed routinely in most medical centers. While electronic thermometry has been validated at the oral site, rectal measurement has not. We performed a controlled study on 84 children comparing mercury-in-glass and electronic thermometry at the rectal site. No significant difference occurred in temperatures between the two methods. We conclude that the electronic thermometer is a valid instrument to measure rectal temperature.

A Practical Approach To Infantile Apnea, Gregory Preston

Henry Ford Hospital Medical Journal

No abstract provided.

Pediatric Emergency Care: A Survey Of Michigan Emergency Departments, David J. Treloar, Gregory Preston, Fred Lamb

Henry Ford Hospital Medical Journal

Recent studies suggest a lack of preparation in emergency medical systems for pediatric patients. Michigan emergency departments were surveyed to determine their degree of preparedness regarding equipment, space, and pediatric on-call coverage. More than 50% of responding emergency departments did not have a pediatrician on call and lacked a pediatric "crash cart," and 34% had to send their personnel to other areas in the hospital to obtain pediatric equipment during resuscitations. This survey suggests a lack of preparation for pediatric emergencies in Michigan.

The Circumcision Decision: A Plea For Informed Consent, Theresa Spinelli

Henry Ford Hospital Medical Journal

No abstract provided.

The Pediatrician's Guide To Food Allergy, John A. Anderson

Henry Ford Hospital Medical Journal

Food allergy occurs in as many as 5% of infants less than 1 year old. Most food sensitivities disappear by age 3 to 4. Most immunologically mediated food allergy reactions are due to type I IgE mechanisms, with skin, gastrointestinal, and respiratory signs and symptoms the most common manifestations. U sing the double-blind, placebo-controlled food challenge (DBPCFC) technique and atopic dermatitis as a model, the most common foods to which children are allergic are cow's milk, eggs, peanuts, wheat, fish, and soy proteins. Anaphylactic sensitivity in older children often involves crustacean seafoods (eg, shrimp), nuts, peanuts, fish, and eggs. Such …

Attention Deficit Disorder: An Overview, Wiley C. Rasbury

Henry Ford Hospital Medical Journal

No abstract provided.

Prevalence Of Respiratory Symptoms And Allergic Sensitivity In Multiply Handicapped Children, Dennis R. Ownby, Mary Logan, Ruth Ann Belfi

Henry Ford Hospital Medical Journal

Among the many challenges of providing care for children with multiple physical and developmental handicaps is the proper management of their respiratory difficulties. This study was designed to evaluate the prevalence of respiratory symptoms in children attending a multidisciplinary clinic for handicapped children. We also used several methods to estimate the prevalence of allergic sensitivity in children with respiratory complaints. Questionnaires concerning respiratory symptoms were completed by the parents of 104 patients. The most frequent complaint reported was snoring in 41% of the children. Of the 39% who had multiple respiratory symptoms, 85% had detectable allergen- specific IgE to cat, …

Child Life: Meeting The Psychosocial Needs Of Children And Families In The Hospital, Christine O. Newman, Carol G. Klingbeil, Roberta B. Abrams

Henry Ford Hospital Medical Journal

No abstract provided.

Adolescent Pregnancy And Sexually Transmitted Diseases: Case Report, Ruby L. Holloway, Richard Smith

Henry Ford Hospital Medical Journal

More than 1 million teenagers become pregnant every year in the United States. Nearly one-half of the pregnancies are carried to term, while a similar number end in abortion. In Michigan this amounts to approximately 34,000 teenage pregnancies (ages 15 to 19). These adolescent patients have a high incidence of sexually transmitted diseases (STDs). Of the pregnant teens at Henry Ford Hospital. 60% present with one or more STDs. We discuss the case of a 13-year-old pregnant girl who presented at five weeks estimated gestation with gonorrhea, chlamydia, and appendiceal perforation, resulting in subsequent spontaneous abortion. Further discussion focuses on …

The Role And Success Of School-Based Clinics, Terence A. Joiner

Henry Ford Hospital Medical Journal

No abstract provided.

Back Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Setting Up An Adolescent Clinic In A Suburban Pediatric Office Group Practice, Patricia K. Stoltz, Kathleen B. Blumer

Henry Ford Hospital Medical Journal

Teenagers in the United States experience significant mortality and morbidity because of high-risk behaviors. Adolescents need routine health supervision aimed at reducing these risks. A Teen Clinic within the Pediatrics Clinic at the Henry Ford Hospital Fairlane Center offers separate facilities, longer appointments, and an emphasis on adolescent issues. This plan is a model for practitioners in various office settings who seek to improve adolescent care.

The Prenatal Development Of The "Synaptic" Structures In The Guinea Pig Pineal Gland, Zhongrong Luo

Loma Linda University Electronic Theses, Dissertations & Projects

Pineal "synaptic" ribbons are a heterogeneous population of organelles. In addition to "synaptic" ribbons (SR) sensu stricto, which are electron-dense rods, "synaptic" spherules (SS) and intermediate forms (IMF) are present. The SS are electron-dense spherical structures, the diameter of which is two to three times the width of the SR. The IMF appear as irregularly formed structures. The SR, SS and IMF are surrounded by electron-lucent vesicles. Their function and origin are unknown and also a knowledge of their prenatal development is lacking. In order to gain an insight into the development of the "synaptic structures, the pineal glands …

Dietary And Hormonal Evaluation Of Men At Risk For Prostate Cancer, Donald J. Pusateri

Loma Linda University Electronic Theses, Dissertations & Projects

Relationships between dietary nutrients and plasma and fecal estrone, estradiol-17β, testosterone, and plasma prolactin levels were studied in young Seventh-day Adventist men: 18 nonvegetarians (NV), 20 lacto-ovovegetarians (LOV), and 15 vegans (V). Blood samples and 3 d dietary records were obtained. Contemporaneously collected diet composites and stool samples were analyzed for fiber. The vegetarians consumed significantly more fiber than the omnivores, while NVs and LOVs consumed more saturated fat than the Vs. Although plasma steroid hormone status did not differ, the Vs had significantly higher fecal estrogen levels than the NVs or LOVs. Plasma prolactin levels were significantly higher in …

Santa Clara Magazine, Volume 31 Number 1, Fall 1988, Santa Clara University

Santa Clara Magazine

12 - MY CHINA YEAR Cathy Morrissey '85 guides us through her year in China, teaching English as a second language in Handan.

19 - IT PAYS TO LET YOUR KID RUN WILD The story of a remarkable relationship between a Japanese firm and Michael Franz '75.

21 - THE REWAK YEARS Alumna-journalist Jeanne Huber describes the way Santa Clara grew during the Rewak administration.

26 - THE DEGNAN WAY How a respected English professor turns undergraduates into professional writers.

Full Issue, Vol. 12

Great Basin Naturalist Memoirs

No abstract provided.

End Matter, Vol. 12, Index

Great Basin Naturalist Memoirs

No abstract provided.

Front Matter, Vol. 12

Great Basin Naturalist Memoirs

No abstract provided.

End Matter, Vol. 12

Great Basin Naturalist Memoirs

No abstract provided.

A Method For The Large Scale Purification Of Hcg (Human Chorionic Gonadotropin) From The Urine Of Pregnant Women, Chun-Shyan Kuo

Chemistry & Biochemistry Theses & Dissertations

A large scale preparation of human chorionic gonadotropin (HCG) from the urine of pregnant women was accomplished by using kaolin adsorption, NH₄OH extraction and DEAE-cellulose ion exchange. A recovery about 81% of HCG and a specific activity in the 2,000-3,000 IU/mg range was achieved using this purification method.

Two HCG activity fractions, HCG I & HCG II, were isolated from DEAE-cellulose chromatography by a stepwise sodium chloride gradient elution. HCG I was eluted at 0.01-0.02 M NaCl while HCG II was eluted at 0.12-0.02 M NaCl.

The differences between HCG I and HCG II have been studied. The …

The Synthesis And Evaluation Of 5-Phenyloxazolidines As Potential Cardiovascular Drugs, Tammy C. Wang

Chemistry & Biochemistry Theses & Dissertations

Drugs such as adrenoceptor antagonists and certain centrally acting agents are known to lower blood pressure and thus serve as clinically useful antihypertensive agents. Norepinephrine 4, a natural ∝-adrenoceptor agonist, is the major agent associated with increased blood pressure in the periphery. Based on a careful structure-activity comparison, a series of substituted oxazolidines, 20, 21, 22 and 23, have been designed as possible antihypertensive candidates. Specifically, 22 and 23 have been synthesized to serve as potential norepinephrine antagonists.

Preliminary evaluation of these compounds indicated that they were not antihypertensive in nature. The more active compound, 23, …