Medicine and Health Sciences Commons^™

Racial Disparities In Plea Bargaining: An Examination Of Coercive Dynamics In The Negotiation Process, Naszya Iman Heidi Bradshaw

Scripps Senior Theses

This research addresses the enduring concerns about the ethical and legal intricacies of coercion in plea bargaining within the U.S. criminal justice system, with a focus on its correlation with racial disparities. This study acknowledges an existing research gap in comprehending the subtle dynamics of coercion and its differential impact on Black and Latin individuals. By employing the Cumulative Disadvantage Theory and Dual Processing Theory, the research aims to investigate the differential susceptibility to coercion during plea bargaining among individuals from Black and Latin communities compared to their white counterparts. Variables such as the severity of criminal charges, the quality …

Psychotropic Polypharmacy On Heart Rate Of Daphnia Magna, Gwendolynne Miller, Brian Bagatto

Williams Honors College, Honors Research Projects

The prevalence of patients being prescribed multiple medications concurrently is significantly rising, and so is the importance of investigating any interactions between medications. One common example—sertraline and clomipramine have been used together to treat obsessive compulsive disorder. Clomipramine, however, is known to cause tachyarrhythmias in some patients. The present study set out to investigate the role of this drug combination on the heart rate of a simple animal model, Daphnia magna, or the water flea. The water flea was exposed to saline, sertraline, clomipramine, or sertraline plus clomipramine, and heart rate was measured subsequently. It was found that the …

Creation Of A Survey And Study On Sleep Habits Of College Students, Sierra Stein

Williams Honors College, Honors Research Projects

Sleep is extremely important in all aspects of life. From the time someone is born to the time they pass they need sleep. It is crucial for their abilities to function and live their day to day lives. However, in different parts of life sleep is more crucial than ever. Young adults/college age students are one of those groups who need sleep but tend to pass up on adequate sleep. Throughout this, there will be the detailed importance of sleep and one way in which sleep can be studied in correlation to academics, physical health, eating habits, mental health and …

The Effects Of Social Support On Recovery Outcomes Of Hip Fracture Patients, Preshecca Ragavan

Williams Honors College, Honors Research Projects

This literature review, completed under the guidance of Ms. Anuja Sarode-Paciorek from Summa Health - Akron, will investigate the effects of social support on the recovery outcomes of hip fracture patients. As part of this literature review, I will collect and analyze several scientific journal articles previously published on this topic to gain an overview of what prior knowledge clinical researchers have already gathered about this topic. As part of the analyses, each article will be thoroughly read and briefly summarized. Then, these summaries will be used to compile a list of a few strengths and a list of a …

Observed Effects Of Physiological Melatonin Dosing On Mda-Mb-231 Breast Cancer Cell Proliferation, Wenli Wu

Williams Honors College, Honors Research Projects

This project seeks to evaluate pharmacological dosing of melatonin on the cell proliferation of MDA-MB-231 breast cancer cell line in culture, using the two solubility carriers: DMSO/water and ethanol. This experiment is a component of ongoing research at the Eaton lab which will elucidate melatonin dose-response toxicology in zebrafish and a possible breast cancer xenograft model for novel treatment therapies.

African American Adolescent Suicidality And Prevention From An Urban School Counselor Perspective, Shannon Franklin

Master's Theses and Doctoral Dissertations

African American adolescent suicidality has become more prevalent, and urban school counselors are positioned uniquely to intervene. This research studied the overarching societal factors in the sociocultural, economic, and political spheres that influence increased suicidality behaviors in African American adolescents from the perspective of urban school counselors. The focus of this research was to hear the lived experiences of urban school counselors regarding the impact of racial discrimination on African American adolescent suicidality. The two theoretical frameworks that were used to support this study are the world-systems analysis theory and critical race theory. This study took a qualitative phenomenological approach …

Survivor Guilt And Posttraumatic Stress Among Young Adult Survivors Of Childhood Cancer, Alexandra Neenan

Master's Theses and Doctoral Dissertations

Childhood cancer survivors are at risk for a variety of adverse physical and mental health outcomes. Posttraumatic stress disorder (PTSD) occurs in a small, but notable, minority of childhood cancer survivors. Little is known about modifiable factors that may increase the risk of developing PTSD as a young adult survivor. One of the difficulties that has been minimally explored in this group is exposure to the deaths of other children with cancer, despite a 25% 15- year mortality rate among children who are diagnosed with cancer. The current study was among the first to explore potential impacts of this high …

Neural Correlates Of Executive Functioning In Preschool Children, Michelle Lobermeier

Master's Theses and Doctoral Dissertations

Healthy development of executive functioning (EF) provides an important foundation for emotional and behavioral regulation as well as academic success. Preschool is a time of rapid EF development, making this a target age group for identifying and intervening on EF weaknesses. Since EF has been historically difficult to behaviorally measure in preschoolers, the current study explores neural correlates of EF as another method by which to understand its development. The goal of the present study is to explore associations between resting state electroencephalography (EEG) power (i.e., theta, alpha, beta) and EF ability in preschool and examine how early regulatory ability …

Befriending Your Anxiety Through The Polyvagal Lens By Utilizing Embodied Imagery, Cassandra Lacroix

Art Therapy | Master's Theses

Many individuals experience anxiety disorders, which can significantly impact their well-being if not properly addressed. Recognizing the need for effective tools to support people with anxiety, this research aligns the key pillars of self-control and present focus awareness of physiological responses through art to harness emotional regulation. This research uses the lens of the polyvagal theory, and looking at embodied imagery, breathwork, and transitional objects to conceptualize ways to help decrease anxiety and enhance body perception and autonomic awareness will be witnessed in participants. The aim of this study was also to establish a strategy that individuals could turn to …

Comparison Between Acute Leukaemia Screening Tube And Lineage Specific Panels For The Diagnosis Of Acute Leukaemia At The Aga Khan University Hospital, Nairobi, Douglas Irimu Munga

Master of Medicine in Clinical Pathology

Introduction; Acute leukaemia is a heterogeneous group of haematological malignancies. It is categorized depending on the immature cells that proliferate and replace the normal tissue in the bone marrow. The broad categories are acute myeloid leukaemia if the immature cells are myeloblasts and acute lymphoid leukaemia if lymphoblasts. Other rare categories are blastic plasmacytoid dendritic cell neoplasm (BPDCN) and acute leukaemias of ambiguous lineage which include acute undifferentiated leukaemia and mixed phenotype acute leukaemias (MPALs). The classification is important as the treatment and management differ hence a timely and accurate diagnosis is paramount. Multiparameter comparison of the immunophenotype is possible …

A Class Of Game-Theoretic And Fokker-Planck Optimal Control Frameworks In Colon And Esophageal Cancer, Mesfer Alajmi Phd

Mathematics Dissertations - Archive

In this dissertation, we first present a new stochastic framework for parameter estimation and uncertainty quantification in colon cancer-induced immune responses. A stochastic process that captures the system's inherent randomness determines the dynamics of colon cancer. The stochastic framework is based on the Fokker-Planck equation, which represents the evolution of the probability density function corresponding to the stochastic process. We formulate an optimization problem that takes individual patient data with randomness present and solves it to obtain the unknown parameters corresponding to the individual tumor characteristics. Furthermore, we perform a sensitivity analysis of the optimal parameter set to identify the …

Addressing Healthcare Disparities Faced By Aging Down Syndrome Populations, Rhea Mistry

Pitzer Senior Theses

Down syndrome (DS) is a chromosomal genetic condition that impacts the development of the body and brain. The life expectancy of individuals with DS has drastically improved over the decades, increasing from 9 years in 1929 to 25 years in 1983 and further reaching 60 years by 2002. Individuals with DS face a variety of prominent co-occurring health conditions that are subject to change over time, including cognitive, visual, and hearing impairments, sleep apnea, cardiovascular defects, Down syndrome regression disorder, and dementia. Despite this increase in life span, DS is still most familiar to pediatric care providers, resulting in healthcare …

Demographic And Clinical Characteristics Of Venous Thromboembolism In Children, Deogracia Sindoiya Owende

Master of Medicine in Paediatrics and Child Health

Introduction: Venous thromboembolism in children is a cause of significant morbidity and mortality worldwide with an increasing annual incidence. The present study aimed to increase awareness as well as attempt to inform the management of paediatric venous thromboembolism in this setting.

Objective: To describe the demographic and clinical characteristics of venous thromboembolism in children aged one month to 18 years at two tertiary hospitals in Kenya.

Methods: A descriptive retrospective chart review of patients aged one month to 18 years diagnosed with venous thromboembolism between January 2014 and December 2022 in two tertiary hospitals in Kenya was …

Management Of High Spinal, An Objective Structured Clinical Examination, Stephanie Williamson, Darienne Lowery

Doctoral Projects

Certified Registered Nurse Anesthesiologists (CRNAs) are responsible for administering safe anesthesia and prompt intervention throughout the continuum of surgical care. During the surgical experience, many potentially life-threatening complications will require timely treatment to prevent irreversible or even fatal consequences. CRNAs are held accountable for recognizing and addressing a wide range of these complications despite their infrequency in clinical practice. Strategic education and training tools must be employed to ensure student registered nurse anesthesiologists (SRNAs) are equipped with the knowledge and critical thinking skills necessary to mitigate crises in the clinical setting.

This DNP project created an Objective Structured Clinical Examination …

Traumatic Heterotopic Ossification: Pathophysiological Mechanisms, Epidemiological Characteristics, And Risk Factors, Nicola Kate Foster

Theses

Traumatic heterotopic ossification (tHO) refers to the complication of pathological formation of ectopic bone in soft tissues, which follows tissue insult secondary to burn, neurological and orthopaedic injury [2]. Common to these diagnoses is the involvement of central and or peripheral nervous system trauma. Although known risk factors are associated with developing tHO, the underlying cellular and molecular mechanisms are not fully understood. Research to date, primarily in single injury cohorts, has provided minimal translatable results [2]. Thus, clinical guidelines for early screening and prophylactic drug therapy are lacking, and treatment options are limited. To move the body of knowledge …

The Development, Implementation, And Evaluation Of An Online Program For Emergency Nurses Caring For Victims Of Interpersonal Violence: A Mixed Methods Study, Melanie Brown

Theses

Forensic nursing encompasses a range of skills that can be utilised across healthcare services and legal services. The delivery of forensic nursing care covers a vast number of roles and practice areas that can improve patient outcome, including the care of victims of interpersonal violence who often face multiple barriers in achieving a positive medicolegal outcome. A nurse’s ability to identify a potential victim and initiate forensic nursing care in an emergency care setting can positively influence the patient’s engagement with support services and the justice system. Despite this, a review of the Australian literature has identified inconsistencies in forensic …

Analysis Of The Immune Response After Readministration Of A Novel Aav6 Gene Therapy Containing Tlr9 Inhibitory Sequences, Sarah Elysse Allen

MUSC Theses and Dissertations

Therapeutic options for the treatment of Surfactant Protein-B (SP-B) deficiency, an autosomal recessive disorder that leads to fatal respiratory distress, are extremely limited with the exception of double lung transplantation. One method for treating this monogenic lung disease is with adeno-associated virus (AAV) gene therapy treatment that delivers the hSFTPB transgene into the lungs. The transient nature of AAV transgene expression led to a need for sustained gene expression, which could possibly be achieved through redosing. The main obstacle with redosing is the innate immune response and subsequent inflammatory response pathways that are activated after recognition of unmethylated CpG motifs …

Novel Engineering Approaches For Orthopedic Injury Treatment And Infection Diagnosis, Cynthia Co

Bioengineering Dissertations - Archive

Bioengineering has made significant contributions to the treatment of orthopedic injury through interdisciplinary approaches. Central to these advancements are many orthopedic implants, including anchors and joint replacements, which have been designed to restore mobility. Despite their functional efficacy, these products have limited lifespan and are associated with many complications, such as implant-associated infection. The success of implant design and function, both in the short and long term, is paramount for enhancing patient outcomes and overall well-being. Therefore, my thesis work is dedicated to addressing these critical challenges, aiming to maximize their treatment effect while minimizing the implant-associated complications.

Long-term patient …

The Effect Of A Neonatal Palliative Care Education Program In Increasing Knowledge And Communication Self-Efficacy Among Nicu Nurses, Shiou-Huei Joy Wang

Doctoral Projects

Background: Neonatal palliative care is crucial to providing comprehensive, high-quality care to neonates with life-limiting or life-threatening health conditions and their families. One significant barrier to the inconsistent provision of neonatal palliative care is the lack of education. This project aimed to deliver an education training program to increase neonatal palliative care knowledge and self-efficacy in NICU nurses. Method: A pre-post-test study design was used to examine the efficacy of an educational training program on NICU nurses’ knowledge and communication self-efficacy in neonatal palliative care. A post-test was administered immediately after the training and again four weeks later to evaluate …

An Exploration Of Mhealth Applications Usage Among Older Adults: A Mixed Methods Study, Francine N. Sutton

Graduate Thesis and Dissertation 2023-2024

This study examines the technology and appointment scheduling habits of older adults over the age of 55 through an exploratory sequential three phase mixed methods study. Phase One of this study examined features of ten existing mHealth applications through a qualitative content analysis, then a mHealth wireframe was developed from the app to replicate in addition to a redesigned version. Phase Two of the study was a thirty-four questions survey with 40 participants that inquired about their background with appointment scheduling, prior experience with technology, and demographics. After that, the mHealth applications were revised into two mHealth application prototypes. Lastly, …

Traditional Chinese Medicine And The Argument For Future Application In The United States, Kylie Nicole Frohlich

Graduate Student Theses, Dissertations, & Professional Papers

No abstract provided.

Examining Potential Causal Associations Of Sedentary Time And Physical Activity With Heart Failure Using Subjective And Objective Measures: A Mendelian Randomization Analysis, Jessica Geller

UNF Graduate Theses and Dissertations

Purpose: The objective of this study was to assess the causal relationship between both subjectively and objectively measured sedentary time (ST) and physical activity (PA) with heart failure (HF) risk, utilizing Mendelian Randomization (MR) approach.

Methods: The present MR used genetic instruments identified for self-reported ST and PA extracted from 51 genome wide association studies (GWAS), encompassing data from 703,901 individuals. The GWAS identified 89 independent single nucleotide polymorphisms (SNPs) associated with leisure screen time. Eleven loci were reported to be associated with moderate to vigorous physical activity (MVPA). From another GWAS examining accelerometer-based activities, three loci were found to …

Integrating Behavioral Health Into Family Medicine: Improving Access To Specialty Care Using A Collaborative Care Model, Christina Stephens

DNP Scholarly Projects

Primary care, an extensive of family medicine remains a key access point for patients entering the healthcare system. Accessing medical care and specialty psychiatric services is limited in rural communities. Patients often find exhaustive wait times, untimely referrals, and reliance on emergency services for crisis management. The primary care provider is able to help their community improve access to behavioral health care by using a collaborative approach. This quality improvement initiative used the framework produced by the AIMS Center at the University of Washington and adopted for use creating an 8-week intensive program in a family medical practice located in …

Empowering Nurse Leaders To Achieve Harmony: Fostering Work-Life Balance, Gilberto Gamba

DNP Scholarly Projects

BACKGROUND: Balancing professional and personal life demands has become a focal point in today’s healthcare organizational culture. Despite the technological advances in providing better and faster healthcare, team members often struggle to achieve work-life harmony while meeting the demands of a growing population of healthcare clients. The evidence highlights nurse leaders as one group for which the identification and implementation of work-life balance interventions is crucial.

METHODS: An original tool based on available evidence was developed and used with a group of nurse leaders participating in an educational activity to engage them in behaviors supporting work-life harmony. A post-educational survey …

Implementation Of Advanced Airway Management Course: A Pilot Quality Improvement Project For Improved Emergency Outcomes For Operating Room And Pacu Nurses, Elizabeth Patry

DNP Scholarly Projects

Background: Airway management has always been central to critical care; it is a complex skill to learn and necessary for patient survival. To properly care for a patient’s airway, the provider must fully understand airway anatomy including upper and lower anatomy and how they work together to allow for oxygen transportation (Day, 2022). Unfortunately, many nursing school curriculums and department orientations are not able to provide the level of education and training necessary. Due to an extreme nursing shortage, many hospitals are not able to provide in depth orientations upon hire and annual review, this lack of professional support affects …

The Impact Of Multidisciplinary Just-In-Time Training On Confidence In The Delivery Of Care In The Humanitarian And Disaster Response Environment, Jennifer Verstreken

DNP Scholarly Projects

Background: Team Rubicon International deploys emergency medical teams with little targeted training on the health and illness patterns common to the geographic region and the type of disasters to which they respond, such as cholera, malaria, and malnutrition. These high-risk, low-incidence illnesses are infrequently seen in Western medical practices. Medical, nursing, and paramedical training programs address these illness patterns in the curriculum. Still, a lack of consistent exposure to the care and treatment of patients with these illnesses can lead to a lack of knowledge and confidence in delivering appropriate care.

Purpose: This quality improvement project aimed to determine if …

Assessing Barriers And Facilitators To School Nurse Recommendations Of Human Papillomavirus Vaccination, Amy E. Dark

DNP Scholarly Projects

Background Vaccine hesitancy among students and caregivers is a pervasive challenge for educational leadership and school health staff, leaving the school community at risk for vaccine preventable disease. The human papillomavirus (HPV) vaccine is an underutilized primary prevention strategy against six HPV related cancers.

Purpose The purpose of this quality improvement (QI) project was to measure the effect of an evidence-based educational intervention and facilitated role play on the knowledge and confidence of school nurses (SNs) when discussing HPV vaccination.

Methods This QI project was performed using a brief educational presentation with facilitated role play and a pre/post survey design. …

Enhanced Neuroprotection And Neuropromotion In Extremely Premature Infants Through Mindful Hands-On Care And Increased Family Involvement, Kristen Sergott

DNP Scholarly Projects

Background: Medical breakthroughs including antenatal corticosteroids and exogenous surfactants have improved survival in extremely premature and extremely low birth weight (EP-ELBW) infants. Currently, babies as young as 22 weeks’ gestation are being actively resuscitated and provided with intensive care in neonatal intensive care units (NICUs) around the world. As a consequence of premature delivery, fragile and immature newborns are at risk for significant morbidities affecting their multiple organ systems. Additionally, such infants encounter neurodevelopmental trauma induced by recurrent stressful experiences ubiquitous to the NICU. Postnatal stress contributes to alterations in the hypothalamic-pituitary-adrenal (HPA) axis and is associated with alterations in …

Racial And Ethnic Disparities In Hospital Practices That Support Breastfeeding In The United States, Jane Lazar Tucker

Open Access Dissertations

Breastfeeding is the optimal form of infant nutrition and has many health benefits for mothers as well as infants (CDC, 2022a; Victora et al., 2016). Though rates of breastfeeding have improved in recent years, disparities in breastfeeding persist among Black and Hispanic women compared to White women (Beauregard et al., 2019; Chiang et al., 2021), despite similar intentions to breastfeed across all racial/ethnic groups (Hamner et al., 2021). Hospital practices that support breastfeeding, such as the baby being placed skin-to-skin immediately after delivery or staying in the room with the mother throughout the hospital stay, are known to predict breastfeeding …

Online Friendships And The Bird’S Nest Drawing In The Age Of The Internet, Ian Wong

Art Therapy | Master's Theses

This study was a qualitative exploration of friendships facilitated through the internet and online video games. The goal was to investigate how online friendships compare to in-person friendships in terms of quality. Three English-speaking participants who played an online video game and had an online friendship provided unique case studies describing the differences between an online and in-person friendship. The Bird Nest Drawing art assessment by Kaiser (1996; 2016) revealed themes of attachment security which helped explain the variations in the friendships. The findings of this study opened the topic of online friendships for further exploration in the field of …