Medicine and Health Sciences Commons^™

Hamstring And Quadriceps Activation During Single Leg Hopping At Varying Frequencies: Electromyography Analysis, Jemma Bosselman

Scripps Senior Theses

Identification of knee motor control strategy is salient both for biomechanical understanding of the lower limb and for medical applications. Integral to knee function are the quadriceps and hamstring, an antagonistic muscle pair. Sub-optimal relative activation of the pair can increase injury potential. Muscle activation patterns are largely activity specific, necessitating muscle control research across various tasks. Single leg hopping has been sparsely studied, particularly for muscle activation in relation to hopping frequency. This project thus aimed to determine the effect of single leg hopping frequency on quadriceps and hamstring activation using surface electromyography (EMG), with the vastus lateralis (VL) …

Cardiometabolic Genomics And Pharmacogenomics In Filipino Americans: A Cross-Sectional Study, Khalifa Y. Alrajeh

Theses and Dissertations

Background: Heart disease remains a leading cause of death in the country, with significant ethnic disparities. Filipino Americans (FAs), the third-largest Asian subgroup in U.S., face an elevated burden of dyslipidemia, a primary modifiable risk factor for heart disease. Objectives: This community-based study addresses critical knowledge gaps by characterizing the cardiometabolic and genetic factors contributing to dyslipidemia among FAs and implications for personalized cardiovascular drug therapies, particularly statin pharmacogenomics (PGx). Methods: We characterized dyslipidemia prevalence in FAs and major ethnic subgroups using nationally representative NHANES data. We examined associations between uric acid (UA) levels and lipid profiles, …

Elucidating The Role Of Fatty Acid Synthase In Apc-Driven Colorectal Cancer, Courtney O. Kelson

Theses and Dissertations--Toxicology and Cancer Biology

Globally, colorectal cancer (CRC) is the second leading cause of cancer related deaths. Currently, there is a growing incidence rate for individuals aged 20-49 years. Genetic and environmental factors contribute to the risk of this cancer. Early detection of CRC allows for the most effective treatment option in which surgical resection of the primary tumor occurs along with adjuvant chemotherapy. This therapeutic approach contributes to 5-year survival rate of 91%. However, surgical procedures and chemotherapy struggles against metastatic and relapsed CRC resulting in 5-year survival rate of 14%. Inefficacious treatments for relapsed and metastatic diseases emphasizes the need for more …

Intergenerational Ties, Sexual Orientation, And Health And Well-Being Of Sexual Minority Adult Children, Beenna Han

Legacy Theses & Dissertations (2009 - 2024)

The three studies in this doctoral dissertation explored overarching themes related to intergenerational relationships, health, and well-being of sexual minority adult children, using data from the National Longitudinal Study of Adolescent to Adult Health (Add Health). The studies have shared but distinctive focal points, including various dimensions of intergenerational relationships, specific subsets of data sources, and methodologies. The first study used two latent growth curve models to examine how intergenerational relationships between adult children and their older parents evolve over time, specifically focusing on the emotional closeness gap between sexual minority and heterosexual adult children. The results showed that sexual …

Understanding The Mechanism Of Ferroptosis Susceptibility Variation In Colorectal Cancer, Aziza Alshahrani

Theses and Dissertations--Toxicology and Cancer Biology

Colorectal cancer (CRC) is the second leading cause of cancer-related death worldwide. Despite the use of chemotherapeutic agents, CRCs remains to be difficult to cure at least partially due to their intrinsic and/or acquired resistance to cell death inducers. Ferroptosis is a form of regulated cell death that caused by the accumulation of lipid peroxides. Studies have shown that dysregulation of ferroptotic pathways is associated with the development of resistance to various cancer treatment. Glutathione peroxidase 4 (GPX4) is a known target for inducing ferroptosis due to its critical role in detoxifying lipid hydroperoxides, and ferroptosis suppressor protein (FSP1) also …

App-Lying Knowledge: Mypcos App Guiding Symptomatic Women To Pcos Awareness, Khanh Hoang

Nursing | Senior Theses

This study delves into the effectiveness of educating women about polycystic ovarian syndrome (PCOS) alongside the utilization of a dedicated mobile health application in raising awareness about PCOS and promoting healthcare-seeking behavior. PCOS, a prevalent endocrine and metabolic disorder affecting 8-13% of women in their reproductive age, lacks definitive remedies, and its underlying causes remain elusive. The primary objective is to establish that empowering women with knowledge about PCOS, facilitated by the MyPCOS mobile app, can lead to increased awareness and encourage them to seek further evaluation from healthcare providers. Rooted in the Health Promotion Model (HPM), the study adopts …

Garden-Based Nutrition Education May Lead To Increased Dietary Knowledge In Low Income Hispanic School Children, Larry Bui

Nursing | Senior Theses

Background: Childhood obesity is a pressing public health concern in the United States, with rates continuing to increase in recent years. This problem disproportionately affects Latino children as well as those from low socioeconomic status. It is well established that nutrition knowledge deficiencies and resulting poor dietary habits are some of the most common contributing factors to childhood obesity. Garden-based nutrition education programs have been introduced to remedy this knowledge deficit; however, a gap remains regarding whether this model can be viable for low-income, culturally diverse populations.
Aim: This literature review investigates the importance of diet in reducing childhood obesity …

The Education Prescription: Exploring The Potential Of Patient Education To Reduce Mental Health Issues In Hormonal Contraceptive Users, Maria Abraham

Nursing | Senior Theses

The many birth control options available impact a woman’s life, as hormonal contraceptives are commonly used but often misunderstood. These contraceptives, which contain progestin only, or estrogen and progestin combined, can come in various forms such as pills, implants, IUDs, injections, the vaginal ring, and skin patches. They offer benefits such as reduced menstrual cramps and ectopic pregnancy risk. However, they may lead to adverse side effects which can include increased blood pressure, nausea, headaches, breakthrough bleeding, and a higher risk of blood clots, with research indicating a potential link between oral contraceptive use and a decline in the user’s …

Chronic Atopic Dermatitis: Symptom Management Using Moisturizers Among Asian American Pediatrics, Ethan J. Brillantes

Nursing | Senior Theses

Background: Atopic Dermatitis (AD), also commonly known as eczema, affects 31.6 million (10%) of the United States Population, with 13% being Asian American or Pacific Islander. A cure is not present for AD; however, the best way to treat AD is with symptom management. While there are many pharmacological treatments that aid with symptom management such as topical or oral corticosteroids, there are also non pharmacological treatments such as moisturizers that can aid with symptom relief of AD as well. Objective: The literature review explores moisturizer use and other non pharmacological methods for symptom management of AD and provides understanding …

The Effects Of Music Therapy On Pediatric Patients With Congenital Heart Defects In The Pre And Postoperative Setting, Janelle Marie Choy

Nursing | Senior Theses

Congenital heart defects is a prominent medical occurrence especially in pediatrics. These defects often require surgeries and extensive treatment plans. These treatment plans often include invasive surgeries and extensive treatment plans which can require long recovery times along with potential surgical complications. This study aims to evaluate the effectiveness of music therapy on pediatric patients with congenital heart defects in the pre and postoperative setting and how music therapy can be implemented in treatment plans to yield effective recovery results for these patients. This research is significant as elevated vital signs and preoperative anxiety are associated with an increased need …

Empowering Low-Income Women With Breast Cancer: Promoting Acupuncture At Community Health Fairs, Katrina Ramos

Nursing | Senior Theses

While research has explored the positive effects of acupuncture on cancer and cancer treatment symptoms, a notable gap exists in understanding its impact on lower-income populations. These individuals encounter barriers to accessing acupuncture, such as limited availability, cost, and provider knowledge. This longitudinal study aims to assess the impact of community health fairs, featuring acupuncture information for breast cancer and chemotherapy-induced symptoms, on the acceptance and utilization rates of acupuncture among low-income women with breast cancer. Collaborating with the Women’s Cancer Resource Center and a local non-profit integrative cancer care clinic in Oakland, we will conduct a three-day health fair …

Doula Support For Hispanic Women, Marilyn Cervantes-Munoz, Daisy Arango-Hernandez

Nursing | Senior Theses

Purpose

This quantitative study will seek to provide valuable insight into the needs and preferences of Hispanic women during labor with the potential benefit of doula support in minimizing their pain.

Methods

A quasi-experimental design study will be conducted, randomizing a convenient sample into two groups consisting of one experimental and one control group, with the objective of evaluating the efficacy of doula presence as a source for pain management in Hispanic women. One hundred Hispanic women will be recruited under the following criteria: 18 years or older, a single fetus pregnancy, gestational age 37 weeks and above, and no …

A Pulse For Progress – Examining The Efficacy Of Best Nursing Developmental Care Practices For Children With Congenital Heart Disease At Risk For Developmental Delay In The Pcicu: A Prospective Quasi-Experimental Cohort Study, Jasmyn Jansen

Nursing | Senior Theses

Emerging advances in pediatric cardiovascular surgery have significantly decreased the mortality rates in infants born with critical congenital heart disease (CHD), in turn, leading to increasing prevalence in adolescence and adulthood. At the same time, developmental delays (DD) are on the rise among children with CHD. Recent research suggests that prolonged exposure to the pediatric cardiac intensive care unit (PCICU), with its environmental stressors, negatively implicates neurodevelopment raising the question, and risk, of DD. In January 2023, the American Heart Association (AHA) issued a scientific advisory calling hospitals to implement developmental care practices for hospitalized infants and young children with …

Addressing Disparity: A Waiting Room Intervention For Preeclampsia Prevention In African Americans, Morgan Semana

Nursing | Senior Theses

Maternal mortality is a pressing, global concern that particularly affects African American women in the United States. African American women face disproportionately a high maternal mortality rate (MMR), with rates more than double that of white women. Preeclampsia emerges as the leading cause of maternal mortality in African American women, driving the need for targeted interventions. To address this issue, a proposed research study aims to investigate the impact of a nurse-led, waiting room, preeclampsia and aspirin effectiveness educational intervention on the knowledge and preeclampsia rates among African American women. The study draws upon existing evidence that supports the use …

Cultural Wounds Find Release: Art Therapy And First Generation Immigrants’ Mental Health, Crystal Soojung Yi, Dennis Chavez Calderon

Nursing | Senior Theses

Background: First-generation immigrants in the United States confront significant mental health challenges rooted in cultural identity conflict. Specifically, these challenges are linked to elevated rates of anxiety, depression, and post-traumatic stress disorder (PTSD), as indicated by Lindert et al. (2009). Art therapy holds promise as an intervention for treating mental health and identity conflicts in a variety of populations. Yet, little is known about how art therapy can improve the experience of first-generation immigrants experiencing cultural identity conflicts.

Objective: This study aims to assess the effectiveness of art therapy in improving the mental health and cultural identity conflicts of first-generation …

Enhancing Athletic Participation: Continuous Glucose Monitoring For Pediatric Type 1 Diabetes Athletes, Danielle Santiago

Nursing | Senior Theses

The difficulties that children and teenagers with Type 1 Diabetes Mellitus (T1DM) encounter are discussed in this thesis, with a focus on how fear of hypoglycemia (FOH) and actual hypoglycemia associated with this chronic illness affects their ability to engage in physical activities, especially organized sports. A common challenge for children diagnosed with T1DM is meeting the daily recommendation of 60 minutes of daily moderate to vigorous physical activity. The purpose of the proposed study is to evaluate if participation in structured exercise (physical education classes and after-school sports) increases among school-aged children who wear continuous glucose monitors (CGM) when …

Empowering Maternal Resilience: A Prenatal Education Program For Mothers And Their Chosen Support Persons For Postpartum Depression, Jennifer Medina

Nursing | Senior Theses

Previous research studies have demonstrated the positive impact education and social support has on reducing the risk of postpartum depression (PPD) when used separately. However, there exists a clear gap in understanding the combined effects of integrating both education and social support during the prenatal period on PPD. This longitudinal quasi-experimental study aims to evaluate the impact of an in-person prenatal PPD prevention program for the birthing person, requiring the presence of a support person on the reduction of PPD. Participants and their chosen support persons will receive information on PPD, including risk factors, signs and symptoms, preventative measures, and …

Improving Spiritual Care Competency Among Intensive Care Unit Nurses: Promoting Holistic Patient Care Towards End-Of-Life, Joanne Nguyen, Dana Bagis

Nursing | Senior Theses

Intensive care unit (ICU) nurses play a crucial role in providing physiological stabilizing care in a dynamic and fast-paced environment, often marked by constant changes and variability in complex patients. Despite their specialization, the aspect of spiritual care tends to be overlooked, particularly in the context of end-of-life care. This is significant because previous studies have shown that a lack of spiritual care leads to poorer health outcomes, decreased coping, increased depression, and diminished quality of life for patients. This research proposal aims to investigate the spiritual care competency among ICU nurses who partake in spiritual care-based training, with the …

A Culturally Sensitive And Intersectional Approach To Healthcare Among Latinx Communities, Gabriela Meza

Nursing | Senior Theses

Various factors, including immigration status, language barriers, age, and socioeconomic status, influence healthcare service utilization among the Latinx population. This study seeks to assess whether culturally sensitive care addressing intersectional factors enhances health access and outcomes in low-income Latinx communities (Purpose). The research proposes a longitudinal quasi-experimental study involving 400 Latinx participants aged 18 and above in low-income urban Los Angeles neighborhoods. A control group of 200 participants and an intervention group of 200 will be established, with the latter receiving culturally sensitive interventions when seeking care during the study. A pre-study survey will collect demographic information, health history, healthcare …

Effects Of Comprehensive Sex Education On Unplanned Pregnancy Rates And Sti Occurrences Among Chinese American Adolescents, Onsheng Seto

Nursing | Senior Theses

Sexually transmitted diseases/infections (STIs) and unplanned pregnancies is a continuing health concern among adolescents. They are more likely to engage in risky behaviors that increase the likelihood for STIs and unplanned pregnancies which emphasizes the need for comprehensive sex education (CSE). This research proposal strives to determine if CSE is an effective tool in reducing cases of STIs and unplanned pregnancies, specifically in Chinese American adolescents. The literature review identified CSE successfully decreasing STIs and unplanned pregnancies in youths. However, limited research correlates the relationship between CSE and Chinese American adolescents. In addition, few studies take cultural influences into account …

Unveiling New Realities: An In-Depth Analysis Of Virtual Reality's Impact On Postoperative Adolescents, Julia Tolentino

Nursing | Senior Theses

The traditional approach to postoperative pain management heavily relies on opioids, but there’s been a surge in their misuse and adverse effects, leading to a significant public health concern. This has led healthcare providers to incorporate a multimodal approach aimed at reducing opioid dependence. This proposal introduces an immersive component, virtual reality (VR), not as a replacement for opioids but as a complementary tool offering distinct advantages for enhancing postoperative pain management. By immersing patients in a virtual environment, VR effectively distracts them from pain and discomfort, allowing for reduced opioid dosages and mitigating the risk of opioid misuse. Additionally, …

Nurse Suicide: Examining Depression And Anxiety In Critical Care Settings, Arianna Bernardine Barata

Nursing | Senior Theses

Nurses play a critical role in healthcare, yet the demanding work environment often exposes them to stressors, leading to the development of depression and anxiety. According to the National Library of Medicine (NLM) (2021), 50.8% of nurses have stress, 74% have anxiety, 70.8% have depression, and 79.1% have at least one of them. Burnout, understaffing, COVID fatigue, alarm fatigue, patient ratios, and disrupted sleep patterns are some of the stressors nurses contend with in every shift. While some nurses may cope and overcome these challenges, many face more severe issues, such as suicide. Nurse suicide is an issue that has …

Effects Of Menopause On Coronary Artery Disease, Angelica Gonzales

Nursing | Senior Theses

Menopausal women, 40 to 60 years old, have an increased risk of developing coronary artery disease (CAD) when they experience hormonal changes. Which then can lead to unwanted cardiac events. Within the literature review of this paper, it was found that there are factors of menopause that may further increase the risk of coronary artery disease in menopausal women. Such factors include whether a woman underwent surgical or natural menopause and the timing when menopause began. Additionally, within the review, hormone replacement therapy (HRT) was explored to determine whether the possible intervention can decrease the progression and risk of developing …

Evaluating The Effectiveness Of Culture Based Nurse-Led Education For Postpartum Depression In Primiparous Asian-American Women, Colleen Peralta

Nursing | Senior Theses

The postpartum period is a critical period in regards to maternal health, marked by various physical, emotional, and psychological changes. Among the vulnerabilities that arise, postpartum depression (PPD) poses significant risks. More specifically, Asian-American mothers with postpartum depression face unique challenges, including the stigma surrounding mental health. As mental health stigma remains prevalent within the Asian-American community, it can make it challenging for mothers to seek out mental health care for postpartum depression. To investigate, primary research articles about the perceptions and experiences of PPD and the interventions used to improve PPD outcomes were examined. A plan for a future …

Unleashing Wellness: Exploring The Impact Of Pet Therapy On Anxiety Reduction, Quality Of Life, And Treatment Adherence In Pediatric Oncology Patients, Karina Brouwer

Nursing | Senior Theses

Pet therapy is a complementary intervention that involves the interaction between a person and animal, with the focus of improving psychological well-being within diverse populations. In particular, children with oncological disorders have increases in anxiety and stress levels, therefore it is imperative to study the impact of animal interventions within this population. This literature critique explores the impact of pet therapy interventions on anxiety, stress, and quality of life perceptions in pediatric oncology patients. This research proposal will investigate how animal therapy interactions within pediatric oncology patients influence their anxiety levels and perceptions of quality of life and how these …

The Impact Of Spanish Language Training For Labor And Delivery Nurses On Postpartum Depression Incidence Among Hispanic Women, Leilani Gutierrez

Nursing | Senior Theses

Postpartum depression and anxiety are experienced by 70-80% of new mothers, and the likelihood is twice as high for Hispanic women compared to caucasian women. Supportive techniques to help monolingual mothers in labor are lacking. A translator's assistance on the hospital floor, such as a video call from an iPad, is often impersonal and lacks the supportive atmosphere that women preparing to give birth need. The primary objective of this study is to explore the potential benefits of providing Spanish-speaking courses to labor and delivery nurses, particularly in cultivating a nurturing and supportive atmosphere for Hispanic mothers during childbirth. By …

Male Caregiver Strain: The Mental Effects Of Being An Informal Caregiver For A Family Member With Dementia And Alzheimer's Disease, Alessandra M. Barillas, Elijah Rammel B. Borja

Nursing | Senior Theses

Background: Caregivers are vital in fulfilling patients' primary care needs, and families prefer them over sending their loved ones to skilled nursing facilities (SNFs). Alzheimer's Disease and Dementia are prevalent conditions necessitating continuous assistance due to memory and cognition impairments. As a result, support is essential for tasks like mobility, feeding, bathing, and perineal care, as well as emotional and physical challenges inherent in caregiving. Purpose: Upon diving into the mental health impacts of serving as an informal caregiver for individuals with Alzheimer's Disease and Dementia, a notable research gap becomes evident, especially concerning male caregivers. This lack of information …

How The Lockdown Of Covid-19 Influenced The Neurocognitive And Psychosocial Development Of Preschoolers, Kay Picson

Nursing | Senior Theses

COVID-19 caused schools to turn to online learning through platforms such as Zoom or Google Meet. The influence and effects caused by the transition to online lessons and quarantine were seen across all patient populations and demographics, but none more so than preschool children, who are regarded as one of the more vulnerable populations due to their susceptibility to change. This research aims to fill gaps in the existing literature by evaluating the similarities and differences of the neurocognitive and psychosocial development of preschoolers exposed to the pandemic and those who were not. This study involves a comparative cohort approach …

Reducing Emergency Department Visits For Children With Autism Spectrum Disorder: Nurse-Led Home Interventions, Teri Nguyen

Nursing | Senior Theses

In the realm of pediatric healthcare, children diagnosed with Autism Spectrum Disorder (ASD) face unique challenges alongside their caregivers. Caregivers face challenges in accessing appropriate support and resources to effectively address the needs of children with ASD. Children with ASD struggle with sensory sensitivities, impaired safety awareness, and difficulties perceiving potential dangers which put them at greater risk for injuries. As a result, children with autism have higher rates of emergency department visits compared to their neurotypical peers. This research aims to assess the effectiveness of nurse-led home injury prevention and education in reducing emergency department visits for children with …

Medical Cannabis In Pediatric Chronic Pain And Diseases, Marissa Colombo

Nursing | Senior Theses

Background: Pediatric chronic pain has seen a disturbing rise which ends up affecting the child’s routine and impacting their family’s lives. Medical cannabis has Food and Drug Administration-approved derivatives, yet the studies that focus on medical cannabis do not discuss targeting pain in pediatric patients. Children who experience chronic diseases and treatment-resistant pain are not normally offered medical cannabis as a treatment option which needs to change. Objective: The purpose of this paper is to explore the impact of medical cannabis within the pediatric population. If children experience pain that is similar to adults, withholding techniques that can help alleviate …