Medicine and Health Sciences Commons^™

Reduction Of Pressure Injury Development In Long-Term Care Residents Using A Pressure Injury Prevention Plan And Communication Alerts, Joseph Osazee

Doctor of Nursing Practice (DNP) Practice Innovation Projects

Background: Accurate communication of changes in residents' skin condition and the provision of appropriate intervention in long-term care is key to ensuring patient safety and well-being through the prevention of pressure injury (PI) development. Effective use of a PI prevention plan and communication tools by certified nursing assistants (CNAs) and nurses can help in this regard.
/="/">Methodology: Thirty-three nursing staff attended an initial I -hour education session on how to identify changes in skin conditions and report them using the as needed (PRN) skin check tool or custom alert tool and implement interventions to prevent PI progression. The Pieper-Zulkowski …

Impact Of Evidence-Based Interventions On Nurse Burnout Among Ambulatory Care Nurses, Haley M. Lupher

Doctor of Nursing Practice (DNP) Practice Innovation Projects

Background: The physical and emotional demands of the nursing profession often cause increased stress and burnout in nurses. If burnout is not addressed, the negative consequences of burnout are perpetuated by one another. Evidence-based interventions, such as meditation, yoga, and physical activity can help reduce nurse burnout.
Local Problem: This project was completed at an ambulatory dermatology clinic that sees approximately 300 patients a day. In recent years, this department has noticed increased nurse turnover and low nurse morale.
Methods: A convenience sample from approximately 30 nurses was utilized. Burnout was measured using the Maslach Burnout Inventory for Medical Personnel …

Nurses' Knowledge, Confidence, And Compliance With An Ambulatory Surgery Discharge Checklist, Heather Van Marion

Doctor of Nursing Practice (DNP) Practice Innovation Projects

Background: Preventable errors in healthcare are fueling the growth of patient safety cultures. Checklists have been found to increase discharge accuracy and efficiency and detection of patient safety concerns before discharge.
Local Problem: Oversight errors can be traced back to poor communication or outdated workflows. Ad hoc communication and knowledge of physician preferences are no longer sufficient for ensuring complete discharge instructions. Methods & Interventions: A discharge checklist was developed and implemented in an ambulatory surgery department to ensure discharge instructions were complete and accurate. Nurses completed a pre and 3-month post-checklist questionnaire assessing their knowledge and confidence in the …

Implementation Of An Induction Of Labor Protocol, Rebecca A. Erickson

Doctor of Nursing Practice (DNP) Practice Innovation Projects

Background: Nationwide focus has been placed on the reduction of incidence of adverse maternal and neonatal outcomes in nulliparous, term, singleton, vertex (NTSV) patients.
Local Problem: Nursing leaders of a maternal child health unit in the upper Midwest recognized a need to reduce the rate of adverse maternal outcomes with evidence-based practice. The facility does not currently have an induction of labor (IOL) protocol.
Methods: The California Maternal Quality Care Collaboration Toolkit to Support Vaginal Birth and Reduce Primary Cesarean Sections was used to create an IOL protocol to prevent adverse maternal outcomes. Categorical outcome data was compared for 6 …

Implementation Of An Oral Sucrose Protocol For Advanced Practice Providers, Cori Shatto

Doctor of Nursing Practice (DNP) Practice Innovation Projects

Background/Purpose: Pain in infancy due to immunization administration often goes untreated. The pain infants experience leads to negative effects on neurodevelopment and pain response. Needle fear develops in infancy and can extend into adulthood, leading to vaccine avoidance and endemic outbreaks. Methods: In a family practice clinic in an upper Midwest state, an oral sucrose protocol was implemented for use by advanced practice providers (APPs). Prior to education on the protocol, a survey was administered to assess the providers’ knowledge, attitudes, and practice (KAP) in relation to oral sucrose. The providers were educated on the benefits and intended use of …

Implementation Of A Daily Protocol To Reduce Central Line Days On A Medical-Surgical Unit, Katherine Wickstrom

Doctor of Nursing Practice (DNP) Practice Innovation Projects

Background: Central line associated bloodstream infections (CLABSIs) are preventable healthcare associated infections (HAI) in the United States. CLABSIs are associated with increased length of hospital stays, mortality, and financial implications for both patients and hospital systems. Extensive research has shown implementing CLABSI prevention bundles can reduce infections and costs. These bundles are often misused, highlighting the importance of bundle compliance and education.
Local Problem: A medical surgical unit in the upper Midwest continues to have delayed central line removal despite a CLABSI prevention bundle. Efforts to decrease central line days were identified as a priority.
Methods: Staff completed education on …

Implementation Of A Prediabetes Risk Assessment And Motivational Interviewing In Adults Ages 35 And Older, Emma Lilleberg

Doctor of Nursing Practice (DNP) Practice Innovation Projects

Background: The American Diabetes Association (ADA) recommends screening for prediabetes using a validated assessment tool in asymptomatic adults starting at age 35. An effective process to raise screening numbers to identify those at risk of prediabetes and diabetes is needed to provide quality care.
Methods: Nursing staff were educated on use of the risk assessment tool and principles of motivational interviewing (MI). Utilizing the ADA risk assessment tool identified those at risk. Nursing staff completed MI with individuals who scored 5 or higher. A readiness for change survey was completed by patients after receiving MI. Additionally, individuals received education on …

Reducing Emergency Department Decision To Admit To Disposition Time Using The Sydney Triage To Admission Risk Tool, Jolyn Sackmann

Doctor of Nursing Practice (DNP) Practice Innovation Projects

Background: Long emergency department (ED) length of stay (LOS) is associated with increased mortality, delay in care, longer inpatient (IP) stays, readmission risk, poor patient satisfaction, and opportunity for error. Within the ED LOS is a quality indicator measuring the time a provider determines a patient will be admitted to the time the patient leaves the ED for an IP unit, called ED-2. Prolonged ED-2 indicates impaired ED output.
/="/">Local Problem: Despite previous interventions, the ED-2 at a rural Midwest hospital was about 63.5 minutes; the goal set forth by the Centers for Medicare and Medicaid is 35 minutes …

Oral Cancer Inequalities: Unmasking Health Disparities Of Vulnerable Populations In The U.S., Harold Nii-Aponsah

Graduate Research Theses & Dissertations

Oral health disparities remain a persistent and pressing public health issue in the United States, with access to dental care and outcomes disproportionately affected by socio-economic status, race, ethnicity, and insurance coverage. This three paper format dissertation highlights various aspects of disparities that do exist in oral health cancer incidence across the United States. The first paper utilizes data from the Surveillance, Epidemiology, and End Results (SEER) program to analyze 19,378 invasive Oral cavity and pharyngeal cancers (OCPC) cases diagnosed between 2018 and 2021, categorized by HPV status. Findings highlight that HPV-positive OCPCs are more prevalent among males, individuals aged …

Non-Alcoholic Fatty Liver Disease And The Components Of Metabolic Syndrome By Race/Ethnicity: Spotlight On Mexican Americans, Roy Valenzuela

Graduate Research Theses & Dissertations

Non-Alcoholic Fatty Liver Disease is one of the most common forms of liver disease in the United States, which occurs when a buildup of fat droplets within the hepatocytes accounts for 5% of the liver’s total weight.

Using the National Health and Nutrition Examination Survey (NHANES), this study evaluated the relationship between suspected NAFLD and Metabolic Syndrome (MetS) and the individual components of MetS among five major racial/ethnic groups in the United States. Furthermore, this study compared the prevalence of NAFLD, MetS, and the components of MetS in four minority U.S. populations with that of non-Hispanic Whites. Data from four …

The Impact Of Waiting Times On Patient Satisfaction And Patient Care At A Tertiary Health Care Institution In Kenya: A Cross-Sectional Study, Soud Seif Soud

Master of Internal Medicine

Introduction: Patients spend significant time waiting for care. This often influences patient satisfaction, perceived quality and access to care, and utilisation of various healthcare services. Waiting time and resulting implications remain understudied in low- and middleincome countries like Kenya. This study aimed to describe the impacts of waiting times on patient satisfaction and care at a tertiary healthcare institution in Kenya.

Method: We conducted a prospective cross-sectional study between March 2023 and July 2023 at the Emergency Room (ER) at Aga Khan University Hospital, Nairobi. Data was collected through a structured questionnaire, looking at demographics and patient wait …

Identifying Youth Appeals In Alcohol Alternative Social Media Content Through Framing, Melina Oneal

West Chester University Master’s Theses

Proposed regulations for alcohol advertising prevent beverage companies from targeting people under the legal drinking age. However, similar regulations for alcohol alternative beverages are less explored, which could allow alcohol alternative products to create awareness for alcoholic beverages among youth. Alcohol alternatives beverages, including no-alcohol and low-alcohol products, are increasing in popularity and can function as compliments to alcoholic products to decrease the total alcohol volume consumed or as substitutes for alcoholic products. Framing theory can be operationalized through the Content Appealing to Youth Index, an index of content elements found in research literature to be appealing to youth, to …

Investigating The Development Of Alcohol Tolerance In The Eskape Pathogens, Hannah Durkee

West Chester University Master’s Theses

Antiseptics and disinfectants are used globally to kill or inhibit the growth of bacteria to prevent infection. Considering the well-documented development of antibiotic resistance, the potential for evolved tolerance to alcohol-based antimicrobial agents raises concern. The ESKAPE bacterial pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter spp.) are a major cause of healthcare-associated mortality and present a threat to public health due to the progression of multi-drug resistance. We conducted an experiment to determine if the ESKAPE pathogens develop an increased tolerance to ethanol upon repeated exposure by selecting for survivors after a …

การศึกษาบทบาทพยาบาลเวชศาสตร์การบิน, ศุภธิดา ผลแย้ม

Chulalongkorn University Theses and Dissertations (Chula ETD)

การศึกษานี้เป็นการวิจัยเชิงบรรยาย มีวัตถุประสงค์เพื่อศึกษาบทบาทพยาบาลเวชศาสตร์การบิน โดยใช้เทคนิคเดลฟาย ผู้ให้ข้อมูลคือ ผู้เชี่ยวชาญด้านเวชศาสตร์การบิน จำนวน 19 คน ประกอบด้วย ผู้อำนวยการหรือผู้บริหารด้านเวชศาสตร์การบิน จำนวน 3 คน แพทย์เวชศาสตร์การบิน จำนวน 3 คน คณะกรรมการหลักสูตรหรืออาจารย์ผู้สอนในหลักสูตรที่เกี่ยวข้องกับงานด้านเวชศาสตร์การบิน จำนวน 3 คน หัวหน้าพยาบาลเวชศาสตร์การบินหรือลำเลียงผู้ป่วยทางอากาศ จำนวน 4 คน และพยาบาลเวชศาสตร์การบินหรือลำเลียงผู้ป่วยทางอากาศ จำนวน 6 คน เครื่องมือที่ใช้ในการวิจัย ประกอบด้วยแบบสอบถามแบบปลายเปิด และแบบสอบถามมาตราส่วนประมาณค่า 5 ระดับ การดำเนินการวิจัยประกอบด้วย 3 ขั้นตอน คือ 1) สัมภาษณ์ผู้เชี่ยวชาญเพื่อรวบรวมความคิดเห็นเกี่ยวกับบทบาทพยาบาลเวชศาสตร์การบิน 2) นำข้อมูลที่ได้จากการสัมภาษณ์มาวิเคราะห์เนื้อหาและนำมาสร้างแบบสอบถามเพื่อให้ผู้เชี่ยวชาญประมาณค่าระดับความสำคัญ 3) นำข้อมูลที่ได้จากการตอบแบบสอบถามประมาณค่าความสำคัญมาคำนวณค่ามัธยฐานและค่าพิสัยระหว่างควอไทล์ และส่งแบบสอบถามให้ผู้เชี่ยวชาญกลุ่มเดิมยืนยันความคิดเห็นอีกครั้ง ผลการวิจัย พบว่า บทบาทพยาบาลเวชศาสตร์การบิน ประกอบด้วย 6 บทบาท ดังนี้ 1) ด้านผู้ปฏิบัติการพยาบาลเวชศาสตร์การบินจำนวน 16 ข้อ 2) ด้านผู้จัดการนิรภัยการบินและนิรภัยภาคพื้น จำนวน 8 ข้อ 3) ด้านผู้จัดการความปลอดภัยและจัดการความเสี่ยง จำนวน 16 ข้อ 4) ด้านผู้ประสานงานและสื่อสาร จำนวน 11 ข้อ 5) ด้านผู้นำการทำงานเป็นทีม การจัดการ และการให้คำปรึกษา จำนวน 18 ข้อ และ 6) ด้านผู้พัฒนาคุณภาพและมาตรฐานการบริการ จำนวน 11 ข้อ

Evaluating The Severity Of Disc Herniation : A Comparative Analysis Of Standing Spine Radiographs And Mri Findings, Suttinont Surapuchong

Chulalongkorn University Theses and Dissertations (Chula ETD)

Objective: The degree of spinal canal compromise in lumbar disc herniation (LDH) significantly influences treatment outcomes. Although magnetic resonance imaging (MRI) remains the gold standard for assessing LDH severity, limited access in primary and secondary care settings can delay diagnosis and referral. This study aimed to determine whether radiological parameters observed on standing spine radiographs can predict the severity of LDH and support timely referral for advanced care. Methods: In this retrospective cross-sectional study, patients diagnosed with LDH who underwent both standing whole-spine radiographs and lumbar MRI between June 2014 and January 2024 were included. Radiographic parameters evaluated included disc …

Participatory Training On Health Literacy To Improve Body Composition Among Female Overweight And Obese-High School Students, Phatthalung Province, Thailand : A Quasi Experimental Study, Chamaiporn Thongphet

Chulalongkorn University Theses and Dissertations (Chula ETD)

Children and adolescents aged 5-19 over 340 million were overweight and obese, the prevalence has risen dramatically. Overweight and obesity are linked to more deaths worldwide than underweight. Using health literacy-focused strategies, the intervention was robust in achieving reductions for participants of varying health literacy status. This study aimed to evaluate the effect of “Participatory Training Health Literacy” on reducing risk behavior and improving body composition among the female overweight and obese high school students, Phatthalung province, Thailand. The study design was 2 designs including cross-sectional study (n=572) design and quasi- experimental research (intervention=36 and control=31). The assessment had conducted …

Autopathography Across Media: Trauma And Fluid Embodied Subjectivity, He (Kristen) Shen

Honors Theses

Illness memoirs with first-person point of view have gained more attention in recent years among medical sociologists and anthropologists. Different from traditional “case histories”written by doctors that are in danger of ignoring patients’ voices, autopathograhical works delineate narrators’ transformative experiences of persons to patients, emphasizing the importance of gaining social understanding of illness. Focusing on three works within the category of autopathography across genres and media forms in the late 1950s and contemporary periods, The Cancer Journals (1980) written by Audre Lorde, The Collected Schizophrenias (2019) written by Esmé Weijun Wang, and The Diving Bell and the Butterfly (2007) directed …

Impacts Of Climate Change On Vector-Borne Disease Burden In The United States: Exploring The Epidemiological Evidence, Leah V. Loetman

Honors Theses

Climate change models predict shifts in vector-borne diseases (VBDs) around the world, including in the United States. However, to my knowledge there has yet to be a comprehensive descriptive epidemiological study examining prevalence, geographic distribution, and trends for all tick- and mosquito-borne diseases in the United States. I compiled data from the U.S. Centers for Disease Control (CDC), which publishes yearly case numbers for 17 vector-borne diseases. However, these publications depend on a scattered framework of state regulations regarding disease reporting. I compiled data from the CDC to determine the current geographic distribution, prevalence, and trends of tick- and mosquito-borne …

Reviving Caribbean Scleractinian Corals: Medication In Ex-Situ Care, Christopher E. Cho

Honors Theses

The Caribbean basin is facing an unprecedented decline in coral reef health, with factors such as coral disease, climate change, and algal overgrowth contributing to the deterioration of these vital ecosystems. In response, land-based facilities have emerged to aid in coral conservation and restoration efforts. One aspect of these conservation efforts involves the treatment of coral ailments, which is still an emerging field within coral conservation. By medicating corals, researchers aim to combat diseases and alleviate stressors that threaten coral health. This practice holds promise for preserving genetic diversity and supporting future repopulation initiatives. This study evaluates the effectiveness of …

Sprtn Metalloprotease As A Target To Sensitize Cancer Cells To Crosslinking Chemotherapy, Cole J. Turner

Honors Theses

Bifunctional alkylating agents have demonstrated high clinical utility as a chemotherapeutic strategy against cancer. These compounds have been well-characterized for their capacity to exert cytotoxicity via interstrand DNA crosslinking. However, the same electrophilic chemistry can also form DNA-protein crosslinks (DPCs) whose contributions to these drugs’ antitumor effects have been less well-defined. Recently, the metalloprotease SPRTN has been implicated as a predominant mediator of DPC repair in mammalian cells. Previous work has demonstrated that SPRTN deficiency increases the sensitivity of cancer cells to DPC-inducing agents such as formaldehyde and cisplatin, but these findings have yet to be translated more broadly across …

The Physicians' Crusade: A Forgotten War On Abortion, Feminism, And The Diversification Of The United States, Lucinda B. Harden

Honors Theses

Abortion in the United States was accessible and widely practiced until the mid- nineteenth century. In 1857 the physicians’ crusade, an anti-abortion political movement led by prominent medical doctors around the country, instigated the widespread criminalization of abortion by the end of the century. I argue that physicians wielded their scientific authority to validate increasingly conservative attitudes about race and gender. They appealed to national xenophobic and sexist backlash that accompanied progressive changes like industrialization and the abolition of slavery, amplifying those fears and offering politicians a source of control over female sexuality and a growing immigrant population: the criminalization …

Development Of Pesticide Labeling Literacy Scale In Thai Rice Farmer, Phiranut Saeneewong Na Ayuttaya

Chulalongkorn University Theses and Dissertations (Chula ETD)

This research was designed as a mixed methods study that aimed to 1) develop and validate a pesticide labeling literacy scale for Thai rice farmers. and 2) evaluate the pesticide labeling literacy level by using the scale development among 400 Thai rice farmers in the central region of Pathum Thani, Chachoengsao, Suphan Buri, Nakhon Sawan, Chi Nat, Sing Buri, Uthai Thani, and Phra Nakhon Si Ayutthaya. The population was selected using a simple random sampling method. Descriptive statistics were used to analyze the general information of rice farmers. The factor analysis of the pesticide labeling literacy scale components (all 5 …

การศึกษาบทบาทพยาบาลผู้เชี่ยวชาญไตเทียม, อัมรินทร์ อรัญญกานนท์

Chulalongkorn University Theses and Dissertations (Chula ETD)

การศึกษานี้เป็นการศึกษาเชิงบรรยาย เพื่อศึกษาบทบาทพยาบาลผู้เชี่ยวชาญไตเทียม โดยใช้เทคนิคเดลฟาย ผู้ให้ข้อมูลคือผู้เชี่ยวชาญจำนวน 18 คน วิธีดำเนินการวิจัยประกอบด้วย 3 ขั้นตอน คือ ขั้นตอนที่ 1 สัมภาษณ์ผู้เชี่ยวชาญเกี่ยวกับบทบาทพยาบาลผู้เชี่ยวชาญไตเทียม ขั้นตอนที่ 2 นำข้อมูลที่ได้จากการสัมภาษณ์มาวิเคราะห์เนื้อหาแล้วสร้างเป็นแบบสอบถามให้ผู้เชี่ยวชาญประมาณค่าแนวโน้มความสำคัญของบทบาทพยาบาลผู้เชี่ยวชาญไตเทียม และขั้นที่ 3 นำข้อมูลที่ได้จากรอบที่ 2 มาคำนวณหาค่ามัธยฐาน ค่าพิสัยระหว่างควอไทล์ และส่งแบบสอบถามให้ผู้เชี่ยวชาญกลุ่มเดิมยืนยันคำตอบ จากนั้นจึงนำข้อมูลที่ได้มาคำนวณค่ามัธยฐาน และค่าพิสัยควอไทล์อีกครั้ง เพื่อสรุปเป็นบทบาทพยาบาลผู้เชี่ยวชาญไตเทียม ผลการวิจัยพบว่า บทบาทพยาบาลผู้เชี่ยวชาญไตเทียม ประกอบด้วย 6 บทบาท จำนวน 87 ข้อรายการ ดังนี้ 1) ด้านผู้ปฏิบัติการพยาบาลผู้เชี่ยวชาญไตเทียม จำนวน 40 ข้อ 2) ด้านผู้สอนและให้คำปรึกษา จำนวน 11 ข้อ 3) ด้านผู้ประสานงานและสื่อสาร จำนวน 7 ข้อ 4) ด้านผู้จัดการความปลอดภัยและบริหารความเสี่ยง จำนวน 10 ข้อ 5) ด้านผู้พัฒนาคุณภาพการพยาบาลการดูแลผู้ป่วยไตเทียม จำนวน 12 ข้อ และ6) ด้านผู้สร้างและใช้นวัตกรรมและเทคโนโลยี จำนวน 7 ข้อ

Distribution Pattern And Risk Factors Of Foot And Mouth Disease Outbreaks In Java Island, Indonesia, Virgilius Martin Kelake Kedang

Chulalongkorn University Theses and Dissertations (Chula ETD)

Indonesia experienced new outbreaks of foot and mouth disease (FMD) in 2022 after being officially free from the disease for several decades. The outbreak started in April 2022 in East Java and rapidly spread to many regions in Indonesia. This study aimed to investigate the distribution pattern and risk factors associated with the FMD outbreaks in Java Island, Indonesia, from 2022 to 2023. Descriptive, spatial, spatiotemporal, and risk factor analyses were employed to examine the outbreak dynamics and contributing factors. The results indicated that the outbreaks were distributed across the island, with East Java being the most affected region. The …

Epidemiological And Molecular Studies On Lumpy Skin Disease Outbreaks In Beef Cattle In Thailand During 2021-2022, Phurida Sripipattanakul

Chulalongkorn University Theses and Dissertations (Chula ETD)

Lumpy skin disease (LSD) is a vector-borne viral disease of cattle caused by the Lumpy skin disease virus (LSDV). LSD is considered as an emerging infectious disease in cattle in Asia and poses a significant threat to cattle production across Africa, Europe, and Asia. This study aimed to describe the epidemiological characteristics of LSD outbreaks in beef cattle in Thailand and to conduct a molecular survey of LSDV infection in beef cattle from May 2021 to December 2022. The study included 594 beef cattle from 257 farms affected by the LSD outbreaks in 28 provinces. We collected hair samples (n=492) …

Protein Expression Of Bone Marrow Mesenchymal Stem Cells Transfected On Green Fluorescent Protein Mrna And Collagen-Coated Titanium Disk, Wasamon Swangvong

Chulalongkorn University Theses and Dissertations (Chula ETD)

New strategies for surface modification have been explored to promote osseointegration and osteogenesis, which are crucial factors for the success of titanium dental implants. Coating the titanium surface with mRNA encoding therapeutic growth factors may achieve these objectives. In our pilot study, we employed green fluorescent protein (GFP) mRNA as a model. Our investigation focused on determining whether titanium disks coated with GFP mRNA encapsulated with lipid nanoparticles and collagen Type I (GFP mRNA-Col) could enhance transfection in human bone marrow mesenchymal stem cells (hBMSCs), in comparison to titanium disks coated with GFP mRNA alone, without collagen. We tested various …

High Prevalence Of Trypanosoma Cruzi Infection In Raccoons (Procyon Lotor) And Associated Risk To Humans In Central Illinois, Esther Onuselogu

Masters Theses

Chagas disease, caused by the protozoan parasite Trypanosoma cruzi, remains a neglected tropical disease and a growing health threat in the United States. Raccoons (Procyon lotor) often coexist with humans in urban and suburban areas and serve as reservoir hosts for T. cruzi. While T. cruzi is rare in humans and domestic animals in the U.S., it is common in wildlife species, particularly raccoons and Virginia opossums (Didelphis virginiana). This study aimed to assess the prevalence of T. cruzi infection in the raccoon population of Central Illinois and evaluate the risk of transmission to humans. …

The Role Of Liver-Specific Transcription Factor Hnf4 In Reprogramming Of Fibroblasts, Mary Odubote

Masters Theses

The mammalian liver, a vital organ with complex functions, relies on a network of transcription factors to regulate gene expression. Fusion of hepatoma cells with fibroblasts often leads to gene extinction, silencing approximately 400 liver-enriched genes, including critical transcription factors such as HNF4. Previous studies revealed that ectopic expression of HNF4 in fibroblasts failed to prevent the extinction of SERPINA1, a liver-specific gene, upon subsequent fusion with hepatoma cells. Here, we sought to investigate the extent to which ectopic expression of HNF4 can reprogram fibroblast cells and prevent gene extinction in hybrid cells.

Using whole-genome expression analysis, we compared RAT1 …

Variability In Perceptions Of Complementary Health Approaches Among Graduate Student Trainees, Delaney C. Bilodeau

Theses and Dissertations

Complementary Health Approaches (CHAs) encompass a diverse range of practices which are often used both independently and alongside conventional medical treatments. Understanding how graduate students training in different fields perceive CHAs is important because these professional trainees will go on to occupy roles as healthcare practitioners, researchers, policy makers, and consumers. This study used sequential rank agreement methods (Ekstrøm, Gerds, & Jensen, 2019) to investigate variations in perceptions of CHAs in a sample of graduate students (N = 416) from 140 possible training programs. Ratings of CHA familiarity, perceptions of CHA legitimacy, and willingness to recommend CHAs were compared …

Investigation Of Brain Function And Structural Development As Risk Factors Of Suicidal Thoughts And Behaviors, Yi Zhou

Theses and Dissertations

Background: Identifying risk factors for suicidal thoughts and behaviors, especially causal ones, will be imperative to improving screening and treatment interventions. To identify replicable brain-based risk factors, there is increasing evidence indicating the need for large sample sizes, in the hundreds to thousands, in order to achieve a sufficient level of statistical power to detect them. Furthermore, longitudinal studies of brain and behavioral factors will be essential to understanding how suicide develops, especially the transition from suicide ideation to attempt. While experimental studies may not be feasible or ethical, genetically informed methods for testing evidence for causation are an alternative …