Medicine and Health Sciences Commons^™

Promoting Awareness In Nurses: Developing Culturally Competent Hair Care Education To Eliminate The Equity Gap For Bipoc Children In Inpatient Settings, Sharlene S. Lansiquot

Doctor of Nursing Practice Projects

Problem

A survey that was administered to staff members on nine units at a pediatric hospital assessing their awareness of hair care for Black, Indigenous, and people of color (BIPOC) indicated a lack of awareness. This impacts the fundamentals of nursing care, which encompasses cultural sensitivity and promoting health equity. In this survey, 12.18% (n=52) of the 427 patients on the nine participating units between December 12, 2023, and January 19, 2024, identified as BIPOC. Although this was the case, the survey sent out on December 12, 2023, to staff members on nine units which included 491 nurses, with 104 …

Reducing Hapi On A Medical Surgical Telemetry Unit, Emily Nicole Johansen

Master's Projects and Capstones

Abstract

Problem: Hospital-acquired pressure injuries (HAPI) are a global issue that harms patients, prolongs lengths of stay, and increases hospital costs and financial burdens. Because HAPIs are preventable, hospital organizations worldwide are implementing prevention strategies to improve the quality of care and quality of life and decrease costs associated with them.

Context: The 24-bed medical-surgical telemetry unit is one of five adult inpatient units within a Northern California hospital. The patient population includes an increased number of patients who are at risk of HAPI. The unit struggles with HAPI prevention, and the staff is challenged with implementing proper HAPI prevention …

Measuring Program Effectiveness Of The Assistive Social Skills And Employment Training, Alyssa A. Chappel

Department of Occupational Therapy Entry-Level Capstone Projects

No abstract provided.

Medical Assistants Adherence To The Jnc-8 Guidelines In A Primary Care Clinic, Mary Jacob

Doctor of Nursing Practice Projects

Hypertension (HTN) is currently one of the most common diseases that is underdiagnosed and under-treated in the primary care setting. The identified gap in practice is that medical assistants need to gain knowledge of the current JNC-8 HTN guidelines and, therefore, do not apply the JNC-8 guidelines to patient management. This project aimed to educate medical assistants in a primary care clinic on the Joint National Committee 8 (JNC-8) guidelines to improve their HTN management knowledge over four weeks. The social cognitive theory and Kurt Lewin’s change management theory guided the project. The project adopted a quantitative, quasi-experimental design whereby …

The Role Of Occupational Therapy & Postpartum Care, Paula A. Rodriguez

Department of Occupational Therapy Entry-Level Capstone Projects

The aim of this study involved researching the role of occupational therapy in the transition into motherhood. The Scale of Occupational Disruption (SOD) was used to gather data about which occupations were the most and least disrupted, as reported by the research participants. Participants were recruited to complete the SOD anonymously through RedCap and were recruited through social media platforms and mom groups. In total, 142 participants participated in the study. Of the total 142 recruited participants, 117 completed the SOD in its entirety, and their data was able to be used for this study. The participants had a mean …

Sensory Processing Assessment In Alzheimer’S Disease And Related Dementias: A Research Capstone Experience, Clarissa Benzarti

Department of Occupational Therapy Entry-Level Capstone Projects

No abstract provided.

Educational Experiences Of Juvenile Offenders In Minnesota, Danielle Petruska

Theses and Graduate Projects

Objective of Study. The objective of this study was to examine the impact of positive adult/teacher relationships in juvenile detention educational settings in Minnesota on juvenile offenders’ perceptions of school, as well as their future plans for attending college after high school. Method. Data were obtained from the 2019 administration of the Minnesota Student Survey, involving 280 juvenile offenders (83 girls) from correctional educational facilities. Hypotheses were tested using correlational analyses to examine the relationship between perceived adult/teacher relationships and school perceptions, as well as the association between these relationships and post-high school plans. Results. Results revealed …

Enhancing The Visual Environment Of Indoor Housed Laboratory Cynomolgus Macaques (Macaca Fascicularis) To Reduce Stress And Maladaptive Behavior, Jeannine C. Rodgers

Theses and Dissertations

Nonhuman primates housed in indoor laboratory environments are generally exposed to nondescript background visual stimuli. This environment is not ideal for species whose primary sensory modality is visual. To provide a more naturalistic visual environment that would potentially improve their welfare, this study assessed the efficacy of a passive natural visual stimulus in the reduction of stress and stereotypy and agonistic behaviors in a cohort of four (2 male, 2 female) Cynomolgus macaques (Macaca fascicularis) housed in an indoor laboratory facility in New York City. The macaques were exposed to four different videos depicting scenes of natural landscapes that were …

Plan Comparison Of Hybrid Dynamic Conformal Arc Therapy (Hdcat) And 3-Dimensional Conformal Radiation Therapy (3dcrt) In Palliative Treatment Of Thoracic Spine Tumors, Maria Juchartz

Masters Projects

Abstract

Introduction

When cancer spreads from its place of origin to a new location, it is termed ‘metastatic’. Metastatic cancer is often not curable, however palliative care can be given. One common method of palliation is in the form of radiation therapy. A common site of metastasis is in the thoracic spine, which has several nearby organs that can make treatment planning difficult. These treatments often consist of three-dimensional conformal radiotherapy methods. The purpose of this study was to compare the traditional 3DCRT techniques to a hybrid dynamic conformal arc technique. HDCAT has been used in previous studies, however none …

Diagnosis, Distress, And Displacement: The Economic Burden Of Breast Cancer In California, Vaibhavi P. Nimkar

Master's Projects and Capstones

Objective: This paper addresses the economic burden of breast cancer and the social determinants of health influencing it among women in California.

Methods: I have prepared a critical review of peer-reviewed literature. The literature was assembled from two databases: PubMed and Springer Link. I limited the search to the years 2014-2024, filtered the results for free full text followed by restriction to a gender filter for women. Of the total forty-two articles gathered, I identified eighteen articles based on the economic burden of breast cancer, excluded all systematic reviews and selected eleven articles including a combination of qualitative, quantitative, …

Advancement In In-Silico Drug Discovery From Virtual Screening Molecular Dockings To De-Novo Drug Design Transformer-Based Generative Ai And Reinforcement Learning, Dony Ang

Computational and Data Sciences (PhD) Dissertations

The field of drug discovery has seen remarkable advancements over the past few decades, transitioning from traditional experimental methods to highly sophisticated computational approaches. One of the pivotal techniques in this evolution is virtual screening, which utilizes molecular docking to predict the interaction between small molecules and target proteins. This method has significantly accelerated the initial stages of drug discovery by enabling the high-throughput screening of large chemical libraries. By simulating the binding affinity and stability of potential drug candidates, virtual screening has become a cornerstone in identifying promising compounds for further development.

A notable application of virtual screening was …

A Scoping Review: Comparison Of Tezepelumab And Mepolizumab In The Treatment Of Persistent Severe Asthma, Alex Liaw, William Chang, Travis Adelman, Josh Guffey, Jason Brumitt

Doctor of Medical Science (DMSc)

Uncontrolled moderate to severe asthma is a disease process that persists despite the maximum therapy of either oral corticosteroids OCS or inhaled corticosteroids (ICS) and long-acting B2 agonists (LABA)1,4 . Severe asthma affects less than 10% of the patients with asthma.5 Asthma can be differentiated as type 2 (Th2) asthma which is characterized by inflammation driven by T-helper (Th) type-2 cells, and non-type 2 asthma, which encompasses all other forms of asthma that do not involve type 2 immune responses. About 50%-70% of the population is diagnosed with type 2 asthma and most patients with severe asthma have at least …

Exploring The Use Of Withania Somnifera (Ashwagandha) In Treating Generalized Anxiety Disorder: A Systematic Review, Samuel Packham, Heather Justice, Travis Adelman

Doctor of Medical Science (DMSc)

Generalized anxiety disorder (GAD) is a common disorder affecting approximately 4% to 7% of US adults. The Diagnostic and Statistical Manual of Mental Disorders defines GAD as persistent and excessive worrying about various aspects of life that occurs most days for at least six months. This anxiety is excessive in both its intensity and its scope, impacting various aspects of life and causing significant impairment in daily functioning. Due to its high prevalence, there is a need for effective and safe treatments. Current guidelines for treatment of GAD recommend either monotherapy or combination therapy using pharmacological and/or psychosocial modalities. Pharmacological …

Treatment Of Plantar Fasciitis For An Individual With An Intellectual Disability That Interferes With Communication And Compliance To Home Program: A Case Report, Ryan J. Ostermeier

Physical Therapy Scholarly Projects

Introduction. Approximately 10% of Americans deal with plantar fasciitis. Plantar fasciitis can lead to negative impacts on quality of life. Furthermore, treatment of individuals with intellectual disabilities affecting communication presents a unique set of difficulties. This case study summarizes the evaluation process and treatment of one female patient with bilateral plantar fasciitis who also has an intellectual disability.

Case Description. This specific patient was diagnosed with intellectual disability secondary to a carbamoyl phosphate synthetase I (CPS) deficiency at birth. She presented to physical therapy at age 35 with bilateral plantar heel pain of 6 months following an increase in activity …

A Bundle Of Care For Prevention, Early Recognition, And Treatment Of Hyaluronic Acid Dermal Filler Associated Vascular Occlusion, Genny Sanders

Doctor of Nursing Practice Papers

Background: Hyaluronic acid (HA) dermal fillers, an injectable used for cosmetic use, are gaining popularity, and are expected to continue to do so in the projected future. With the rise in the number of patients seeking these procedures there is a correlated rise is adverse events, including the complication of vascular occlusion. Vascular occlusion has the potential for detrimental outcomes, and clinicians performing these procedures are responsible for educating patients about these risks. As whole, the healthcare community must be prepared.

Purpose: A quality improvement (QI) project was created to help clinicians prepare, prevent, recognize, and treat hyaluronic acid dermal …

Implementation Of An Evidence-Based Intervention To Improve Human Papillomavirus (Hpv) Vaccination Rates Of Children Newly Admitted To A Residential Facility., Krista Danielle Fitzgerald

Doctor of Nursing Practice Papers

Background: The Centers for Disease Control and Prevention (CDC) estimates that more than 42 million Americans are presently infected with the Human Papillomavirus (HPV). The nurse practitioner (NP), who provided primary care to children at the residential facility, reported that only 60-70% of children were consented for HPV vaccination.

Purpose: The purpose of this evidence-based intervention was to have 90% of newly admitted children consented and vaccinated for HPV. The specific aims of this project were to (1) increase staff HPV/HPV vaccine knowledge, (2) implement an updated evidence-based consent form, and (3) increase the HPV consent and vaccination rates.

Methods: …

Exploring The Role Of Occupational Therapy In Recovery High Schools For Adolescents With Substance Use Disorder And Co-Occurring Mental Health Disorders, Taylor P. Buono

Department of Occupational Therapy Entry-Level Capstone Projects

Substance use is a public health crisis, and adolescents struggle the most with substance use disorder (SUD), which often persists into adulthood and even until midlife (Estreet & Privott, 2021; Mattila et al., 2022; Rothman & Jimenez, 2023; Volkow & Blanco, 2023). School performance is often affected by the adverse effects of drug and alcohol use among adolescents, and multiple risk factors for substance use occur in the school context, such as drug-using peers, availability of substances, and academic challenges (Finch et al., 2017). Recovery high schools (RHSs) are safe and supportive alternative educational environments that provide additional support not …

Transitioning From Inpatient Rehabilitation To Home In Veterans With Spinal Cord Injuries, Alexis Tucci

Department of Occupational Therapy Entry-Level Capstone Projects

This capstone project aimed to develop a comprehensive guide to support Veterans transitioning home from inpatient rehabilitation, enhancing their quality of life. The guide provides educational materials, recommendations, and valuable resources for clients and their families to utilize both during their hospital stay and after discharge. The primary objective was to understand the ongoing needs of veterans with spinal cord injuries post-discharge and to help bridge the gap between the SCI inpatient unit and home.

Faculty Attitudes Toward The Preparation Of Baccalaureate Nursing Students For Practice In Hospital And Non-Hospital Settings, Lisa Radley

Dissertations

The ongoing nursing shortage worsened in recent years following the COVID-19 pandemic, has resulted in increasing concerns about future deficits in the nursing workforce. Many nurses are approaching retirement age at a time when the overall demand for healthcare services is expected to increase. Changes in nursing education have been recommended to ensure that the next generation of nurses are willing and prepared to meet the needs of an ageing population. Nursing faculty will have important roles in the education and mentoring of students to prepare them to care for diverse populations in a variety of practice settings. Understanding faculty …

Interpretation Models For Prostate Lesion: Detecting, Explaining, And Understanding., Mehmet Akif Gulum

Electronic Theses and Dissertations

Prostate cancer is a major public health concern, affecting millions of men worldwide. While early detection and treatment of prostate cancer is critical for improving patient outcomes, the detection of prostate lesions is even more important for timely intervention and management of the disease. Prostate lesions are abnormal growths or lumps within the prostate gland, which may or may not be cancerous. The timely detection and accurate diagnosis of prostate lesions is crucial for effective treatment and management of the disease. In recent years, deep learning models have shown promise in accurately detecting and characterizing prostate lesions using advanced imaging …

Unraveling The Complex Dynamics Of Cardiac Fibrosis: Ccn1 As A Novel Regulator Of Scar Collagen Architecture And Structural Integrity In Myocardial Infarction., Annalara Garland Fischer

Electronic Theses and Dissertations

Expansion of the extracellular matrix (ECM), known as fibrosis, accompanies nearly all forms of cardiac disease; however, its most significant and complex manifestations arise following a myocardial infarction (MI). This process, principally led by fibroblasts, constitutes a necessary and adaptive response acutely to fill the void from cardiomyocyte necrosis following ischemic injury due to the heart’s lack of regenerative capacity. This acute response never fully resolves and contributes to ongoing collagen accumulation in non-infarcted regions, leading to diminished ventricular compliance, ongoing myocyte loss, and attrition in function—culminating in heart failure. Further, recent research demonstrates that concomitant with progressive increases in …

Exosomal Cannabidiol: A Promising Candidate For Targeted Oral Delivery Against Breast Cancer., Disha Nagesh Moholkar

Electronic Theses and Dissertations

Cancer therapies are limited by lack of specificity, selectivity and numerous adverse effects. Repurposing potential anticancer compounds with appropriate drug carriers can help overcome these drawbacks. In our present study, we address the major obstacle for cannabidiol (CBD): its low oral bioavailability, using exosomes. Exosomes (Exo) are promising non-toxic and biocompatible drug delivery vehicles Our project aims are to address the research gap by formulating exosomal cannabidiol (ExoCBD): a tumor-targeted oral delivery system for the treatment of breast cancer. The targeting approach relies on the overexpression of folate receptors at the tumor site by using folic acid functionalized exosomes (FA-Exo). …

Regulation And Mechanisms Of Ocular Dominance Plasticity At Cellular Resolution., Thomas Christopher Brown

Electronic Theses and Dissertations

Sensory systems throughout the brain require experience to aid in proper wiring during development. While forming, many sensory systems have periods of heightened sensitivity where alterations in the quality of experience can have a profound impact on cortical responses throughout life. These periods of heightened sensitivity have been coined critical periods. In the visual system of mice a critical period for ocular dominance has been well studied and defined between postnatal days nineteen and thirty-six. During this critical period, altering visual experience by suturing one eye closed called monocular deprivation (MD) shifts responses in cortex towards the non-deprived eye. Similar …

Health Professions Education And Critical Action Engagement: A Mixed Method Analysis., Leonda Richardson

Electronic Theses and Dissertations

Poorer health outcomes disproportionately impact racial/ethnically minoritized (e.g., Black Indigenous People of Color, or BIPOC) populations in the U.S. One plausible reason for the persistence of poorer health outcomes among this population is the teaching of racialized curricular content within academic health professions programs. This includes the absence of appropriate context through explicit socio-political curricular content (SPC) and critical pedagogy (i.e., social and structural determinants of health, history of racism in health care, social justice concepts; dialogue and reflective writing). Racialized curriculum is thought to initiate and/or exacerbate existing racial biases, cultural incompetence, and perpetuate dominant medical ideologies and myths …

Molecular Mechanisms Of Exercise-Stimulated Resolution Of Inflammation And Its Dietary Dependence., Ernesto H. Pena Calderin

Electronic Theses and Dissertations

Diet-induced obesity and adipose tissue (AT) inflammation that ensues sets the stage for systemic metabolic inflammation, disrupted insulin signaling, and eventual type 2 diabetes (T2D) development. At the center of this pathology lies a disruption in endogenous inflammation resolution pathways characterized by an imbalance in lipid mediator production (greater abundance of pro-inflammatory to pro-resolving lipids). Additionally, obese states are characterized by adrenergic deficiency, especially in response to physical activity. Inflammatory processes have been experimentally mitigated by either the pharmacological inhibition of pro-inflammatory signals (i.e., Leukotriene B₄ (LTB₄) and its receptor BLT1, which establishes a potent chemotactic stimulus …

Epidural Stimulation For Urogenital Dysfunction In The Spinal Cord Injured Rat., Natasha Lorraine Wilkins

Electronic Theses and Dissertations

Spinal cord injury (SCI) is a devastating, life changing event that greatly impacts quality of life. SCI can have body-wide, multi-system consequences including dysfunction within the urogenital system. Challenges with the urinary system include urinary incontinence, urine retention, and detrusor-sphincter dyssynergia all of which require maintenance through the regular use of catheters. Sexual dysfunction in men, who comprise nearly 80% of the SCI population, includes erectile dysfunction, anejaculation, retrograde ejaculation, poor expulsive force during ejaculation, and poor sperm quality. The treatment for sexual function in SCI men is focused more on fertility through the collection of sperm for insemination procedures …

Associations Of Natural Vegetation In Relation To Colorectal Cancer Hotspots And Colorectal Cancer Survival., Johnnie Newton

Electronic Theses and Dissertations

Background: Across Kentucky, county-level geographic disparities in colorectal cancer (CRC) incidence and outcomes exist. Given the heterogeneity of lifestyle, socioeconomic (SES), and environmental factors within a county, more granular approaches should be used to identify local areas with a high CRC burden and identify the area-level factors that may contribute to geographic disparities. Studies reported that living in greener areas is associated with beneficial health outcomes, including lower mortality. Despite growing evidence that natural vegetation (greenness) exposure is associated with increased physical activity and obesity, two well-known CRC risk factors, epidemiological studies investigating the association of residential greenness exposure with …

Covid-19 Infection And Mortality, Patient Comorbidities, Social Determinants Of Health, And Environmental Influences In Kentucky., Shaminul Hoque Shakib

Electronic Theses and Dissertations

OBJECTIVES: To investigate patient- and county-level disparities in COVID-19-related mechanical ventilation use and mortality by SDOH factors and comorbidities among Medicaid non-pregnant adult beneficiaries in Kentucky. Additionally, to compare the association of COVID-19-related infections and mortality with social mobility and weather between Indiana and Kentucky during the stay-at-home period (March 1 to May 15, 2020). METHODS: In chapter 2, an administrative claims-based retrospective cohort study was conducted using the Kentucky Health Facility and Services database. Medicaid beneficiaries who were hospitalized during 2020–2021 in Kentucky were considered in the logistic regression and the Cox regression model to estimate the risk of …

Understanding Barriers To Effective And Equitable Covid-19 Response Through The Evaluation Of Essential Needs Program In Jefferson County, Ky., Haritha Pallam

Electronic Theses and Dissertations

This study utilized a multi-method study approach to assess the effectiveness of the Essential Needs Program (ENP), aimed at aiding priority groups in successfully completing isolation or quarantine (I/Q) during the COVID-19 pandemic. It commences with an overview of the COVID-19 pandemic's history and the role of ENP as a local emergency response strategy to mitigate community spread. Chaos and systems theories were employed to comprehensively understand disaster phenomena and factors influencing individual adoption of protective measures during the pandemic. Additionally, institutional decision-making models and implementation science were utilized to elucidate how public health stakeholders coordinated ENP services provision and …

Enhancing The Anticancer Effects Of Apiaceae Spice Phytochemicals., Jared Lee Scott

Electronic Theses and Dissertations

Breast cancer (BC) is a leading contributor to the death of women and is the most common type of cancer. Many chemotherapy drugs are developed from plants, and some plant extracts can exhibit significant anticancer activities while also having less toxic side effects. The Apiaceae plant family consists of several species that are used as culinarily spices which have demonstrated antioxidant, chemopreventive, and anticancer activities. The encapsulation of anticancer phytochemicals into naturally produced membrane-bound nanoparticles known as exosomes could improve their systemic distribution and efficacy. Exosomes are involved in cell-to-cell communication through the delivery of proteins, nucleic acids, and small …