Medicine and Health Sciences Commons^™

The Discriminative Stimulus Properties Of Morphine And U-50,488h In A Three-Key Assay: A Mu And Kappa Opioid Discrimination In The Pigeon, Malath Makhay

Dissertations

Opiate drugs have been classified in two-choice assays according to their ability to produce generalization in animals to the prototypicix opiate, morphine, versus vehicle, or to the k opioid, U -50,488H versus vehicle injections (Picker & Dykstra, 1987). A three-choice discrimination procedure, in which subjects discriminate among morphine, U -50,488H , and vehicle injections, might afford a greater degree of precision in characterizing the subjective effects of opioids. The feasibility of such a procedure was demonstrated in the present study, in which five pigeons were trained to discriminate among injections of 5 .6 m g/kg morphinel 5 .6 m g/kg …

Correlates Of The Mmpi-A Immaturity (Imm) Scale In An Adolescent Psychiatric Population, Eric Albert Imhof

Psychology Theses & Dissertations

Despite numerous theories of adolescent ego development, there is no objective measure of ego development or maturation targeted for the assessment of adolescents. The Immaturity (IMM) Scale developed for the Minnesota Multiphasic Personality Inventory - Adolescent (MMPI-A) was designed to fill this void in adolescent assessment. The present study examined the concurrent validity of the IMM Scale based on sixty-six adolescents (13-18 years old) in an inpatient setting using four prominent measures of maturity, i.e., The Defining Issues Test (DIT), the Washington University Sentence Completion Test (WUSCT), the Extended Objective Measure of Ego Identity Status - Second Revision (EOM-EIS-2), and …

An Enzyme-Linked Immunosorbent Assay For The Detection Of Cardiac Myoglobin Using Monoclonal Antibodies, Deborah F. Kelly

Chemistry & Biochemistry Theses & Dissertations

The most prevalent life-threatening disease worldwide, secondary to coronary artery thrombosis is Acute Myocardial Infarction (AMI). Increases in three clinical markers have been explored as an early means of AMI detection: Cardiac myoglobin, and the two specific cardiac isoforms of Creatine Kinase, CK-MM and CK-MB. However, myoglobin levels have shown to give a more accurate correlation (R = 0.89) than does Creatine Kinase evaluation. Therefore, we have developed a two-site Enzyme-Linked Immunosorbent Assay (ELISA) using monoclonal antibodies against myoglobin isolated from human heart tissue. This assay is based on specific anti-genantibody interactions and is sensitive at the nanogram level. We …

A Validation Of Target Heartrate Formulas Used In Swimming, Tasha Kay Litwinski

Masters Theses

The purpose of this study was to explore whether procedures used to establish target heart rates (THRs) for running are applicable to front crawl swimming. Eight male and 22 female fitness swimmers from Western Michigan University participated in this study. Their exercise durations under three experimental conditions were compared. The conditions were: (a) Condition 1, a treadmill run at an intensity equal to a THR of 85% of heart rate reserve (HRR); (b) Condition 2, a front crawl swim at an intensity equal to 85% of HRR; and (c) Condition 3, a front crawl swim at an intensity equal to …

The Cultural Adaptability Of Dental Hygiene, Medical Laboratory Sciences, Nursing And Physical Therapy Faculty, Irene Mary Connolly

Dental Hygiene Theses & Dissertations

The purpose of this study was to determine the cultural adaptability of full time faculty in the College of Health Sciences, Old Dominion University, Norfolk, Virginia. The sample consisted of 40 health science faculty representing dental hygiene, medical laboratory sciences, nursing and physical therapy. The principal investigator personally administered the Cross-Cultural Adaptability Inventory (CCAI), a 50 item instrument, which contains questions to measure the construct cultural adaptability and its four dimensions: emotional resilience, flexibility/openness, perceptual acuity and personal autonomy. The CCAI is not targeted to one particular culture, but rather is designed to be culture general.

Analysis of …

Relationship Between Design Marketing Strategies And Toothbrush Purchases By Consumers, Cynthia Lynn Garvin

Dental Hygiene Theses & Dissertations

The purpose of this study was to investigate whether a relationship exists between design marketing strategies of toothbrushes (handle size, color, and shape; brush head size and shape; and bristle firmness and formation of toothbrushes) and toothbrush purchases made by consumers. To understand what consumers preferred, a self-designed, 24 item questionnaire, "Toothbrush Design and Consumer Preferences," was given to a convenience sample of 300 subjects ranging from ages 20 to 60 and over from the Old Dominion University campus in Norfolk, Virginia. Responses from each item were analyzed using frequency and percentages of responses, contingency tables, Kendall's tau b, and …

The Assessment Of Osteoinductivity Of Human Allograft Demineralized Bone Matrix By In Vivo And In Vitro Assay Models, Min Zhang

Theses and Dissertations in Biomedical Sciences

The osteoinductive potential (osteoinductivity) is a very important aspect of demineralized bone matrix (DBM) as a biomaterial. This study is directed at establishing qualitative and quantitative assays of the osteoinductivity of human DBM. Further aspects of this study include an assessment of the effects of the production process, matrix characterization, and donor related factors on osteoinductivity of the DBM.

Athymic mice were chosen as the animal model for use in the in vivo bioassay. Implantation of DBM in muscle pouches provided for much higher osteoinductivity (remineralization to 10% calcium) than subcutaneous site implantation (remineralization to 1.6% calcium). Histological observations revealed …

Association Between Nutrient Intake And Risk Of Coronary Heart Disease In California Seventh-Day Adventists, Peter Pribiš

Loma Linda University Electronic Theses, Dissertations & Projects

Dietary habits are believed to be major determinants of risk of coronary heart disease (CHD). Studies of high and low risk populations have suggested several nutrients to be protective or hazardous against CHD. Most published work since 1984 on diet and CHD in the Adventist Health Study (AHS) population examined either foods or food groups. This study investigated ten nutrients as exposure variables and their relationship to CHD risk. A cohort of 23,616 nonsmoking, non-Hispanic white California Seventh-day Adventists was followed for six years beginning in 1976. Extensive dietary information was collected at baseline, as well as values of traditional …

Job Accommodation In The Automobile Industry : Addressing The Problem Of Lateral Epicondylitis, Thanigaivel Ashwin Raj

Theses and Dissertations (ETD)

Cumulative trauma disorders are musculoskeletal problems such as carpal tunnel syndrome, rotator cuff tendinitis, and epicondylitis which can affect assembly line workers. The injuries are thought to result from repetitive motions performed under excessive loads in anomalous postures. The project aimed to design, build, install, and evaluate worksite accommodation at the Saturn plant for a worker with right lateral epicondylitis. The goal was to make her fully functional in her original team which required addressing the injurious aspects of the task that caused or aggravated her injury.

A process of observation, interview, and analysis identified “the door mount” operation on …

Photochemotherapy Of Vascular Cells With 8-Methoxypsoralen And Visible Light: A Novel Approach To The Prevention Of Post-Angioplasty Restenosis, David Marshall Lee

Yale Medicine Thesis Digital Library

No abstract provided.

Use Of The (3)H-Tetracycline Rat Model In The Study Of Skeletal Compartmentalization And Metabolism Of Calcium In The Maturing Male And Female Rat And The Role Of The Skeleton In Calcium Homeostasis In The Adolescent Male Rat, Darrin Lee Demoss

Theses, Dissertations and Capstones

The (3)H-tetracycline bone labeling procedure was employed to monitor bone resorption from urinary loss curves in male and female rats of various ages. In addition, whole body dry skeletal mass and the loss of (3)H-tetracycline from individual bones was determined. It was found that the dry skeletal mass/body mass ratio of 24-week-old females was 30-40% greater than that for males. The urinary loss of (3)H-tetracycline was described by a double exponential equation indicating the presence of two distinct and independent exchangeable bone compartments. Both compartments decrease in size with age, but their label loss activities were different. The label loss …

Regulation Of Melanogenesis In B16 Mouse Melanoma Cells By Protein Kinase C (Pkc), Harish Mahalingam

Theses, Dissertations and Capstones

The pigment cell-specific expression of tyrosinase and TRP1 has been shown to be important for the production of melanin in pigmented cells. Using a pigmented cell line, B16 mouse melanoma, we obtained evidence that PKC plays a major role in regulating melanogenesis. Chronic treatment with phorbol dibutyrate (PDBu) leads to downregulation of PKC activity and protein levels. This is accompanied by a loss of pigmentation which is correlated with a 50% reduction and a complete loss of TRP1 and tyrosinase respectively. Similar results were obtained with Northern and Western blotting indicating that PKC may regulate the steady state levels of …

Subtalar Joint Biomechanics, Tom L. Baumgartner

Physical Therapy Scholarly Projects

Subtalar joint movement is transmitted proximally to the lower extremity and distally to the forefoot during gait. Thus, the entire lower kinetic chain is influenced by abnormal subtalar joint biomechanics. If the subtalar joint is forced to compensate for structural deformities of the foot and leg, various lower extremity injuries are likely to develop. The purpose of this study is to examine the normal and abnormal biomechanics of the subtalar joint. In the process, the clinician will be able to identify various subtalar joint abnormalities and relate these to their respective lower kinetic chain pathologies. By correctly assessing the cause …

Physical Therapy Interventions For Falls In The Elderly, Melanie Benson

Physical Therapy Scholarly Projects

The elderly in America represent a population that is continually growing. As part of the aging process, various changes occur that contribute to falls. Therefore, as the number of elderly people in America increases, the possibility of falls in the elderly also increases.

The consequences of falls in the elderly are significant. Some of the more serious consequences include functional decline, increased medical cost, and death. Therefore, the scope of the problem is clear; strategies to prevent falls and treat those who have fallen are indicated.

The purpose of this independent study is to review the literature pertaining to falls …

An Exploratory Study Of Heroin Addicts' Perceptions Of Methadone Treatment, Sandra Ellen Nehring

Theses Digitization Project

Methadone treatment continues to be the most widely used treatment modality for heroin addiction despite continued controversy. The efficacy of methadone treatment has been determined primarily by statistical research of program outcomes. This study explored heroin addicts' perceptions of methadone treatment.

Assessment Of The Health Needs Of The Communities Served By Kaiser Permanente Of Riverside, Jennifer Van Arsdall

Theses Digitization Project

The purpose of this community needs assessment was to explore the unmet health needs in some of the communities of Riverside County, to discover which populations are most adversely affected by these unmet needs, and to determine what barriers hinder individuals from getting their needs met. United Way of the Inland Valleys, in cooperation with Kaiser Permanente of Riverside conducted this study as part of their community based needs assessment.

Perspectives Of Administrative And Direct Services Providers For Substance Abusing Women And Their Children: An Exploratory Study, Susan Gail Lacey, Willem Vanderpauwert

Theses Digitization Project

No abstract provided.

A Research Study On Emotional Adjustment Of A Spouse Following Stroke, John P. Vlasic Ii

Theses Digitization Project

This research project focuses on age as a predictor in the emotional adjustment of a spouse following his/her partner's stroke. The medical records of 80 stroke cases were reviewed at Kaiser Permanente Medical Center, Fontana, California. Patients and spouses were examined in two age groupings, age 55 and below, and ages 56 and above. Study of these two age groups afforded the most meaningful division to study spouse adjustment.

A Pre-Test/Post-Test Analysis Of Value, Behavioral And Spritual Changes In Drug Treatment, Ralph Olav Jacobsson

Theses Digitization Project

No abstract provided.

Factors Affecting Hispanic Adolescent Substance Abuse, Patricia Joanne Williams

Theses Digitization Project

No abstract provided.

Restraint Use: Impact Of An Employee Educational Program In A Skilled Nursing Facility, Elizabeth Ann Roybal

Theses Digitization Project

No abstract provided.

The Relationship Between The Level Of Alcohol Consumption And The Incidence Of Spousal Abuse In Euro-American And Hispanic Male Populations, Gabriela Patricia Gomez

Theses Digitization Project

Text includes English and Spanish versions of questionaires and consent forms.

Indicators Of Delay Between Recommendation For Community Outpatient Treatment And Release Into A Conditional Release Program, Dennis Howard Littlefield, Eric Harley Summers

Theses Digitization Project

The mentally ill who have been found not guilty of a crime by reason of insanity (NGRI), appear to be at risk in several areas when confronted with the judicial system. The purpose of this study is to determine whether the factors which predict recidivism of NGRI patients in Community Out-patient Treatment (COT) also inhibit a patient's release into a conditional release program (CONREP).

A Literature Of Change: Slave Narrative Rhetoric In Ralph Ellison's Invisible Man, Andrew Jack Loverde

Theses Digitization Project

No abstract provided.

Correlation Study Of Methamphetamine Abuse And Resultant Levels Of Child Neglect, Marjorie Nodelman-Niedringhaus

Theses Digitization Project

This positivist research project will attempt to show a correlation between levels of child neglect and proportionate levels of methamphetamine abuse. The term abuse will be used to refer to the chronic, compulsive use of methamphetamine in such a manner, that it will assume a central and negative role in the individual's life style and will result in impaired functioning and parenting.

A Study Of The Effects Of Lesbians' Sexual Orientation To The Disease Of Alcoholism, Teddie Valenzuela Chapin

Theses Digitization Project

No abstract provided.

The Relationship Between Vertical Jump Scores And Peak Force Measurements Of An Isokinetic Leg Press, David M. Silkey

Physical Therapy Scholarly Projects

This study evaluated potential correlations between related closed kinematic chain strength measurements on a Kin-Com isokinetic machine and a functional strength test. The correlation between standing vertical jump height and isokinetic leg press measurements were statistically analyzed. The following measurements were obtained from 22 subjects (mean age of 24.4 years): a body weight measurement, a vertical jump score, and the force measurements of an isokinetic leg press at 90°/second on each leg. Pearson correlation coefficients were significant (p < .001) when power quotient scores (vertical jump height multiplied by body weight) were compared to leg press results. However, second-order partial correlation coefficients did not find a significance (p > .005) between vertical jump scores and isokinetic leg press results when weight and gender were considered. A significant difference (p < .001) existed between left leg press and right leg press measures. Although isokinetics are useful for lower extremity assessment, this study found that the isokinetic leg press may not be appropriate in determining functional ability.

In-Home Health Care And Hospitalization Status, Donna Lee Maeser

Theses Digitization Project

The purpose of the study was to describe the relationship between in-home health care services for elderly patients who were recently discharged from inpatient care and re-hospitalization rates. The design was descriptive and the hypothesis was that the provision of in-home health care services would mitigate a decline in the health status, of an elderly patient, following discharge from inpatient care and prevent re-hospitalization.

Project Success: Examining The Impact Of Supported Work Programs On Clients' Self-Esteem And Quality Of Life, Susan Anne Brisco, S. Denise Christensen

Theses Digitization Project

Among the goals of recent supported work employment programs is improvement of competitive employment opportunities for individuals who suffer from chronic mental illness, and for whom competitive employment outcomes are poor. This study examined the effects of a vocational rehabilitation program, Project Success (Skills Upgrade: Client Centered Empowerment Supportive Services), on self esteem and quality of life for chronically mentally ill participants.

Male Sexual Abuse: A Retrospective Study, Gary Wayne Deaton

Theses Digitization Project

No abstract provided.