Medicine and Health Sciences Commons^™

Molecular Studies Of Splice Sites In The Canine Dystrophin Gene, Hayley Durling

Theses : Honours

The development of an effective therapy for Duchenne Muscular Dystrophy (DMD) is one of the primary goals of all DMD/Becker Muscular Dystrophy (BMD) research. Golden Retriever Muscular Dystrophy (GRMD), an animal model of DMD is a fatal degenerative myopathy. Unlike the mdx model, the GRMD dog more accurately reflects the phenotype shown by human DMG patients, making the model better suited for the investigation and assessment of potential therapeutic approaches. The GRMD mutation, a base change from A to G in the 3' splice acceptor site of intron 6, results in exon 7 skipping which disrupts the translational reading frame. …

To Immunize Or Not To Immunize, That Is The Question! An Investigation Into The Reasons Behind Parents' Decisions In Immunizing Their Children Against Whooping Cough In Western Australia, Eliena Kirov

Theses : Honours

Demographic data on the immunization status of Australia indicates that Western Australia has relatively low immunization coverage for whooping cough. Australian quantitative studies have been carried out on parental attitudes in Australia towards immunization, but there has been no analysis of parents' reasons for their decisions. This study identified the key issues that influenced the decisions made by the target group of parents and explored their decision-making in more depth. The data from this study could also be used to supplement the information currently available to health workers. Eight participants with children between the ages of 2 months and 6 …

Relationships Among Attributional Style, Behavioral Problems, And Gender In Learning Disabled Vs. Non-Learning Disabled Adolescents, Janet Cervalli

Seton Hall University Dissertations and Theses (ETDs)

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Detection Of Antibodies Against Brucella Abortus In Bovine, Celso Arturo Moreno Paredes

Theses and Dissertations

The present investigation was made in the Laboratories of microbiology of the Ability of Cattle Sciences of the Polytechnic Superior School of Chimborazo, with samples obtained in the Municipal Camal Riobamba and the Community of Tunshi San Nicolás. The incidence of Brucellosis was analyzed in six more important cattle areas of the county using the antigens Brucella abortus and Rosa of Flare. The experimental units were obtained under a systematic sampling. The experiment had a duration of 4 months. The experimental results underwent the following analyses: variance, percentages, stockings, standard deviation, limit for the estimate error. According to carried out …

The Relation Between The Nutritional Status And The Acute Diarrhetic Diseases In Children Younger Than Five Years Of Age In The Indigenous, Black, And Mestizo Ethnic Groups Of The Rural Area In The Imbabura Province, 1998-1999, Tanya Vaca

Theses and Dissertations

The study conducted in the rural area of the province of Imbabura included a total of 518 families that when compared with the estimated sample of 96%, 42.7 % corresponding to the indigenous ethnic group, 28.15% to Black and 25% to mixed-race ethnic groups, these differences of involvement between ethnic groups is due to the fact that the indigenous population is greater than the two remaining populations. Of the 518 families studied they were able to obtain a total of 794 children younger than 5, in which 48.5% pertaining to the male sex and 51.4% to the female sex. In …

Family-Of-Origin Distress And Intimacy In Later-Life Couples, Paul James Birch

Theses and Dissertations

Married couples aged 55-98 were surveyed regarding their perceptions of family-of-origin distress, their affective communication and problem solving communication skills, and their emotional intimacy. Two 2-way ANOVAs were performed with husbands' (model 1) and wives' (model 2) emotional intimacy scores as dependent measures and family-of-origin distress scores as the independent measures. Then both models were re-analyzed with affective communication and problem solving communication entered as co-variates. Results suggested that for both husbands and wives, emotional intimacy was affected by family-of-origin distress. Additionally, intimacy was affected by the distress in their spouses' family-of-origin in both models. Post-hoc analyses suggested that as …

Characterisation And Optimisation Of Gypsum Crystallization, Catherine H. Shannon

Theses

Gypsum is produced as a by-product during the citric acid production process at ADM Ringaskiddy. The particle size and filterability of the gypsum has a critical bearing on the overall citric acid production rate. Prior to August 1996, research in the area of gypsum crystal optimisation at ADM had concentrated on the application of vortex mixing to perform the gypsum formation reaction. While the gypsum crystals produced with vortex mixing were found to be desirably clear of microcrystalline gypsum, the crystals were considerably smaller and more difficult to filter and wash. This research project sought to retain the advantages conferred …

The Atomic Force Microscope In The Elucidation Of Leukocyte Abnormality, Derbrenn O'Connor

Theses

The aim of this project was to investigate the novel use of the atomic force microscope (AFM) as a technique in the elucidation of leukocyte abnormality. To this end, comparative AFM imaging and elasticity studies were performed on normal and myeloid leukaemic leukocytes.

Initially, an evaluation of techniques for the isolation of specific leukocyte (e.g. lymphocytes, granulocytes, etc.) populations from whole blood or leukocyte concentrates, was carried out. It was found that a silanised glass surface failed to select and immobilise a leukocyte population. However, centrifugation of whole blood in an Isopaque-ficoll gradient solution yielded a viable mixed leukocyte population …

Benchmarking Financial Operations Using The Premier Operations Outlook Database, Margaret M. Thompson

Community & Environmental Health Theses & Dissertations

Acute-care hospitals have come under increased pressure to reduce costs while increasing the quality of providing care. Historically, increasing costs of providing care has had the greatest impact on the reduction of operating margins necessary to expand capital and for repayment of debt. Facilities can benchmark internal historical data to identify areas where costs have increased and are able to explain the factors that contribute to the increases. One of the challenges facing hospitals in their efforts to reduce operating costs is how, what, and where, do they obtain comparative data to benchmark the cost of operating medical facility to …

Classification Of Participants Into Two Health Resource Utilization Groups By The Health Enrollment Assessment Review (Hear) Survey, Jody W. Donehoo

Health Services Research Dissertations

The study examined the ability of the Health Enrollment Assessment Review (HEAR) survey instrument to classify participants into one of two groups according to utilization of health resources anticipated in the following year. Developed by the U.S. Air Force, the HEAR survey is used worldwide by the Department of Defense for enrollees in TRICARE Prime, the military's adaptation of the HMO model of managed care. Individual HEAR reports are prepared for survey participants and their primary care providers in TRICARE Prime. Although it is currently administered worldwide to a majority of the 8.4 million health care beneficiaries of the Department …

Needle Localization For Breast Biopsy: The Patient's Experience, Marian De Walt Morgan

Psychology Theses & Dissertations

The needle localization procedure for breast biopsy (NLP) can be painful and distressing for some women. This study was carried out to learn what factors might increase or decrease NLP pain and distress, and to gain insight into possible interventions to make the procedure more comfortable for all patients. One hundred and thirty-eight women were surveyed following breast needle localization at two central Virginia hospitals. The influence of eight variables (lidocaine, self-regulation, anxiety, worry about breast cancer, breast tenderness, finding mammography painful, difficulty with surgery, and distress of blood drawing) on four outcome variables (pain incidence, pain intensity, pain unpleasantness, …

The Direct And Indirect Patient Benefits Of Orthopedic Physical Therapy Specialization, Amy Lynne Dipman

Masters Theses

This research surveyed 25% of Orthopedic Certified Specialists to determine the direct and indirect patient benefits resulting from the American Physical Therapy Association specialization process. The newly developed questionnaire included questions pertaining to demographics, professional activities, and professional opinions regarding specialty certification. The results showed a statistically significant relationship between the number of PT’s on staff at a facility and the amount of therapist mentoring. Overall, only 50% of the therapists subjectively reported improved patient care secondary to specialization. The qualitative data showed that many therapists reported providing high quality care prior to specialization. Patients are receiving direct and indirect …

Psychoneuroimmunology And Healing Touch In Hiv Disease, Jo Lynne Wheeler Robins

Theses and Dissertations

The purpose of this study was to ascertain the effects of Healing Touch (HT) on well-being and neuroendocrine function in individuals living with HIV disease. A total of 27 males completed the 4-week HT intervention. Each weekly HT session lasted 30 minutes and consisted of only the chakra connection, Because of the small sample size and the impact of gender on neuroendocrine and immune function, women were not included in this study Dependent variables included well-being as measured by three well-being and two psychological distress instruments, serum serotonin, salivary DHEA and cortisol, and a variety of enumerative and functional measures …

Great Suffering, Great Compassion: A Transcultural Opportunity For School Nurses Caring For Cambodian Refugee Children, Teresa L. Tellep

Master's Projects

The unique cultural ways of Cambodian refugee families, combined with the physical and psychological health problems inherent in their refugee experience, present challenging and rewarding opportunities for school nurses to engage in the process of transcultural nursing. The authors discuss the profound and devastating impact of the refugee experience upon the mind, body, and spirit of Cambodian children. The purpose of this exploratory and descriptive study was to understand the nature and meaning of a school district's cross-cultural team's experiences of providing health care for Cambodian refugee children. Focus group interviews of school nurses and Cambodian liaisons were conducted, utilizing …

Rehabilitation For Deafened Adults: A Puzzle With Missing Pieces, Miguel Oswald Aguayo

Theses and Dissertations (Comprehensive)

This study explored the psychological and social impact of adventitious deafness, and the rehabilitation services that were offered to individuals who acquired this condition in adulthood. Qualitative interviews were conducted with a sample of eight deafened adults, who were recruited from across Ontario. The results show that medical interventions (e. g., audiometric testing, hearing aid provision, and cochlear implantation) were relied on exclusively as a rehabilitation approach in providing care to deafened people. None of the study participants were offered individual, family, or group counselling by their hearing health service providers. This lack of attention to the socio-emotional needs of …

Investigation Of The Contractile And Regulatory Proteins In Malignant Hyperthermia And Normal Skeletal Muscle, Louise C. Norbury

Theses : Honours

Malignant hyperthermia/hyperpyrexia (MH) is a serious human skeletal muscle disorder that manifests itself during general anaesthesia. Currently, the most reliable method of diagnosing this disease is the in-vitro contracture test (IVCT). This procedure is both highly invasive for the patient and expensive to perform. The skinned muscle fibre technique is less invasive, and could possibly be used as an alternative diagnostic test for MH. In this study, skeletal muscle samples were obtained from B adults (age 23-54 years) undergoing elective surgery at Royal Perth Hospital. Six patients were diagnosed as normal (controls) and two equivocal for MH (MHE). Using the …

The Relationship Between Percent Deficit Ideal Body Weight And The Prevalence, Severity, And Healing Of Pressure Ulcers, Cheryl Anne Masters

UNF Graduate Theses and Dissertations

This retrospective study determined whether percent deficit ideal body weight (IBW) was a risk factor for the prevalence, severity or healing of pressure ulcers. This study hypothesized that nursing home residents below their IBW with pressure ulcers have more severe, higher prevalence, and a slower healing rate than resident who are above their IBW. Medical record data were analyzed for all subjects that met the selection criteria from April, 1997 to April, 1998. Fifty-eight subjects aged 39 to 104 years were assigned to one of two groups (Group 1(n=28) were less than 99% of IBW; Group 2 (n=30) were greater …

The Relationship Between A Functional Throwing Performance Test And Strength Of Various Scapular Muscles, Karen L. Bos, Kellie S. Gehrs, A. Louise C. Hester

Masters Theses

The purpose of this study was to determine the relationship between the strength of the upper trapezius, middle trapezius, lower trapezius, and serratus anterior, and overhead throwing accuracy in 52 female collegiate softball players. The correlation between manual muscle testing (MMT) and hand-held dynamometry (HHD) was also examined. The Functional Throwing Performance Index (FTPI) was used to measure throwing accuracy. Spearman’s correlation analysis demonstrated no correlation between the strength assessments and throwing accuracy, as measured by the FTPI. Moderate correlations were found between MMT and HHD strength assessments of the lower and middle trapezius and serratus anterior muscles. A poor …

Effect Of Asymmetrical Loading And Walking Time On Surface Emg Activity Of The Lumbar Paraspinal Muscles, Michael Aenis, Angela Bueche, Brian Trembly

Masters Theses

BACKGROUND A high incidence of back pain is associated with carrying loads asymmetrically and is believed to be influenced by the amount of weight involved and the distance carried. PURPOSE (1) To study the effects of asymmetrical loading on lumbar paraspinal muscle activity. (2) To document ratings perceived exertion (RPE) for carrying an asymmetrical load. METHODS Electromyography (EMG) readings were obtained at the L2/L3 paraspinal level of 12 males and 12 females. All subjects completed three randomized 9-minute trials consisting of walking on a treadmill while carrying an asymmetrical load of either 0, 10 or 20% of their body weight. …

Advisors' Knowledge Of Requirements For Admission To The Physical Therapy Program At Grand Valley State University, Laura Irrer, Elizabeth Knight, Joel Vander Wall

Masters Theses

The purpose of the study was to identify the accuracy and extent of knowledge among G.V.S.U. academic advisors and the sources used to obtain information regarding the physical therapy (P.T.) admission process. Surveys were distributed to 45 advisors of pre-P.T. students. Nineteen surveys were returned and six respondents were chosen for an interview. Interpretations of the data were made using a qualitative coding system.

The authors found the advisors were inaccurate in their knowledge of the weighting of G.P.A . and interview and the role that physical appearance and leadership plays in the admission process. Advisors were accurate in the …

Emg Measurements Of Paraspinal Muscles And The Implications Of Adapting Hand Placement Protocols When Using Passive Extension Exercises, Mark Randell, Geoff Willson

Masters Theses

The purpose of this study was to determine if there is a significant difference in the EMG activity of the paraspinal musculature, based on the width of hand placement used in the McKenzie prone press-up position.

EMG recordings were taken using surface electrodes placed on the lumbar paraspinal musculature of thirty normal, volunteer subjects. These recordings were taken while the subject was in the prone press-up position. This was repeated three times with different widths of lateral hand placement. The resultant EMG recordings were normalized using a recording from a maximal effort of an isometric contraction. The mean EMG recording …

The Effects Of Prosthesis Use Versus Non-Use On Forward Reach Distance In Children Ages 5 To 15 With Unilateral Upper Extremity Amputation As Measured By The Functional Reach Test, Mary E. Weber, Scot G. Smith

Masters Theses

The purpose of this study was to investigate the possible differences in maximal forward reaching distance in children with unilateral upper extremity amputations while wearing and not wearing a prosthesis using the Functional Reach (FR) test. Trends were noted between FR scores of these children and children without disabilities.

Four children, ages 5-8, completed the FR test using the intact arm under two conditions, “prosthesis-off” and “prosthesis-on”. A paired, two-tailed t test (a = .05) was used to determine the statistical significance of the means of differences in FR scores between the two conditions.

No statistically significant difference was found …

Patients' Perceptions Of Physicians' Role In Smoking Cessation By Age And Readiness To Stop Smoking, Chris Van Ryn, Joel Wetzel

Masters Theses

It is imperative for health care providers to initiate an individually tailored program to counsel smokers in a more effectively. Finding patients’ perceptions of their physicians' role in smoking cessation is critical to aid healthcare providers to design an individualized plan to get patients to quit smoking. 68 smokers who presented to their family practice clinics in the rural area of Hastings, Michigan completed self-administered questionnaires. The questionnaires assessed patients’ perceptions of their physicians’ role according to the 4 A s protocol (asking, advising, assisting, and arranging), with a focus on age groups (18-29, 30-49, and >50) and stage of …

The Life Experiences Of Male Occupational Therapists As It Relates To Career Choice: A Qualitative Study, Jason R. Bomia

Masters Theses

This study examined the life experiences of male occupational therapists and how various life experiences influenced their choice of career. Research in occupational therapy has not addressed this topic, focusing instead on external influences, such as salary, advancement and prestige on career choice for male therapists. In order to study more intrinsic influences of male occupational therapists, this study interviewed male therapists using semi-structured interviews and hermeneutic data collection and analysis techniques. The results indicate a dynamic relationship between personal history, selfexpression and professional issues that contribute to how meaningful occupational therapy is to the males in this study. This …

The Effects Of Animal-Assisted Therapy At A Long Term Care Facility, Sarah Kendziorski, Carol Treacy

Masters Theses

This thesis is a qualitative study on how resident pets impacted the lives of residents in a nursing home. Through the hermeneutic process, ten participants were interviewed to determine their relationships with the animals. Five common themes emerged from this study; (a) the participants enjoyed the companionship of pets, (b) the participants found pleasure in feeding the pets, (c) the participants enjoyed petting the animals, (d) most of the participants were unable to care for the animals, and (e) a resident animal would be an important factor in choosing a new nursing home for these participants. This thesis supports the …

Functional Effects Of Botulinum Toxin-A Intramuscular Injections In A Patient With Traumatic Brain Injury: A Single Subject Case Design, Christina M. Higel, Molly L. Arndt

Masters Theses

This single subject case design sought to evaluated the long-term and short-term effectiveness of Botulinum Toxin-A (BTXA) treatment in conjunction with directed physical therapy on spasticity, active range of motion (AROM), passive range of motion (PROM), Functional Independence Measurement (FIM) scores, and motor performance in a patient with TBI. Researchers hyopothesized that directed physical therapy in conjunction with BTXA would maximize a subject’s motor control and performance. An "A₁-BC-B-A₂” single subject design, scheduled to last six months and three weeks, was proposed. Clinically significant changes were defined as: a decrease by one point for the Modified …

Perceived Concerns Surrounding The Utilization Of Physical Therapy Aides In Michigan, Jill Bydalek, Greta Swasey-Hadlock

Masters Theses

Utilization of support personnel to perform physical therapy treatments has been a controversial topic in the physical therapy profession for many years. As Managed Care and other health care changes emerged, physical therapists have been pressured to cut costs while maintaining productivity. The use of non-licensed personnel became common place to meet these demands. The purpose of this study was to investigate five research questions. First, to what extent do physical therapists delegate patient treatment and utilize physical therapy aides in Michigan? Secondly, does aide utilization differ based on: the ways in which aides are identified to patients, various settings …

Examination Of The Reliability And Validity Of Rancho Los Amigos Observational Gait Analysis, Heather Groth, Sarah Novak

Masters Theses

The Rancho Los Amigos Observational Gait Analysis system (Rancho OGA) is a standardized approach utilized to assess gait impairment for various diagnoses. Physical therapists, orthotists, and physicians utilize Rancho OGA for clinical decision making and recommending treatment interventions for gait disability. This study examined the reliability and concurrent validity of Rancho OGA from gait files obtained from the GVSU/Mary Free Bed Center for Human Kinetic Studies. Comparisons were made between computerized 3-D gait analysis and Rancho OGA data from videotaped records of cerebral palsy gait to determine the level of agreement utilizing the Kappa statistic and percent agreement. Results indicated …

Validation Of The "Timed Up And Go" Test As A Functional Mobility Assessment Tool In The Pediatric Population, Susan Carman, Christina Rook, Cathy Ruprecht

Masters Theses

The purpose of this study is to determine the concurrent validity of the Timed Up and Go (TUG) as an assessment of functional mobility in the pediatric population. The TUG scores were correlated with the Pediatric Evaluation of Disability Inventory (PEDI). Eighteen subjects with a variety of cognitive and physical disabilities, aged 6 to 7 years, were recruited. A one-tailed Spearman’s Rank Correlation Coefficient was used to analyze the scores. A weak inverse relationship between the TUG and PEDI scores (r_s = -0.386, p = 0.075) was found when the scores from all participants were analyzed. A moderate inverse …

The Relationship Between A Functional Throwing Performance Test And Strength Of Various Scapular Muscles, Karen L. Bos, Kellie S. Gehrs, A. Louise C. Hester

Masters Theses

The purpose of this study was to determine the relationship between the strength of the upper trapezius, middle trapezius, lower trapezius, and serratus anterior, and overhead throwing accuracy in 52 female collegiate softball players. The correlation between manual muscle testing (MMT) and hand-held dynamometry (HHD) was also examined. The Functional Throwing Performance Index (FTPI) was used to measure throwing accuracy. Spearman’s correlation analysis demonstrated no correlation between the strength assessments and throwing accuracy, as measured by the FTPI. Moderate correlations were found between MMT and HHD strength assessments of the lower and middle trapezius and serratus anterior muscles. A poor …