Medicine and Health Sciences Commons^™

Respiratory Kinematics Of Adult Males During Graded Listening Tasks, Laura Lerette Gingrich

Dissertations and Theses @ UNI

Covert speech movements have been observed to increase with linguistic complexity during listening tasks. This study investigated the presence of covert respiratory movements during listening tasks of increasing complexity to answer the following research questions: 1. Do normal adult male listeners aged fifty and above without central nervous system injury change from rest breathing patterns to speech breathing patterns while listening to passages of increasing complexity; 2. Is there a greater shift towards speech breathing while listening to passages of greater complexity? Chest wall kinematics often male participants were obtained and analyzed for significant changes from rest breathing during four …

Season Long Evaluation Of Relationships Between Several Variables And Hitting Efficiency In Four Division I Volleyball Players, Patricia Raelyn Dietz

Dissertations and Theses @ UNI

Throughout a collegiate volleyball season game performance fluctuates game to game and even match to match. The purpose of this study was to investigate relationships between several anthropometric and independent variables and hitting efficiency in four Division I athletes. Subjects were four female Division I volleyball players who participate in a hitting position. Subjects were tested weekly on vertical jump approach height (VJ), reactive strength index (RSI) using an AMTI force plate, BM (BM), and body composition (BF%). Pearson product moment correlations showed no significant correlations between hitting efficiency and each of the indpendent [sic] variables for each individual or …

Phylogenetics And New Approaches To Vaccine Development For West Nile, Arun Venkatesh Iyer

LSU Doctoral Dissertations

West Nile virus (WNV) was first isolated in 1937 from a febrile Ugandan woman. WNV now has a worldwide distribution from Australia and India in the east to Europe and the United States in the west. The first human cases of WNV in the United States were detected in New York in 1999. The North American isolates were also found to be highly neuroinvasive and neurovirulent and in many cases leading to mortality or permanent CNS sequelae among humans. WNV was first isolated in Louisiana in 2001. The genome of this virus named LSU-AR01was sequenced and a detailed genetic analysis …

Phonemic Awareness And Sight Word Reading In Toddlers, Alicia Tonya Mcinnis

LSU Doctoral Dissertations

This study investigated emerging phonemic awareness skills and printed sight word recognition abilities in two-year-old toddlers using plain text and MorphoPhonic Face words on flash cards. MorphoPhonic Face words were used to determine if this learning process is enhanced when words are iconically represented to show the first sound and the word's meaning (purposefully creating idiosyncratic cues) using pictures superimposed into the letters. Sixteen (16) age-matched toddlers were assigned to alternate treatment groups and received exposure to both printed and MorphoPhonic pictured words three times weekly for six weeks. During each session, children were taught 16 sight words (8 in …

Characterization And Comparison Of Cell Frequency, Growth, And Multipotential Differentiation Of Adult Mesenchymal Stromal Cells Derived From Equine Bone Marrow And Adipose Tissue, Martin Andreas Vidal

LSU Doctoral Dissertations

Equine bone marrow-derived mesenchymal stromal cells (MSCs) and adipose tissue-derived stromal cells (ASCs) were compared for frequency within their respective tissues, cell doubling characteristics and differentiation multipotential in culture based on histochemical staining and compositional analysis. Equine MSCs and ASCs from young adult horses were harvested and isolated from sternal bone marrow and supragluteal subcutaneous adipose tissue, respectively, and grown up to passage 10 (P10) to determine cell doubling characteristics. Limit dilution assays were performed on primary and passaged (P2, P4) MSCs and ASCs to determine the frequency of colony forming units with a fibroblastic phenotype (CFU-F), and the frequency …

The Investigation Of Treatment Outcomes For Adults With Chronic Brain Injury Following Intensive Multidisciplinary Treatment, Donna Mineo Fitzgerald-Dejean

LSU Doctoral Dissertations

Although communication sciences and disorders (COMD) research supports intensive treatment for individuals with chronic brain injury, funding to provide these services is limited. This study explored the use of interdepartmental university resources to provide an intensive, multidisciplinary chronic brain injury program. Methodologically, treatment regimes were designed with clinical faculty as practicum experiences for COMD master’s degree students. Subjects with a single onset head injury or cerebral vascular accident greater than one year were recruited to participate in the Intensive Treatment, Weekly Treatment or Control Groups. Pre, Post, and Post-Post Testing were used to measure cognitive-linguistic, quality of life and physical …

The Zinc Induction Of Heme Oxygenase-1 Gene Promoter In Mouse Hepa Cells, Salim M. Alawneh

LSU Doctoral Dissertations

Heme oxygenase-1 (HO-1) catalyzes the initial and rate-limiting reaction in heme catabolism (yielding equimolar quantities of iron, carbon monoxide, and biliverdin), which is further metabolized to bilirubin by biliverdin reductase. HO-1, an important enzyme with antioxidant and cytoprotective properties, functions against oxidative stress generated in response to heme and to various stress stimuli, such as zinc. The cytoprotective function of HO-1 is dependent on both the activities of the reaction products and on the inducibility of the heme oxygenase gene (hmox-1), which is regulated primarily at the level of gene transcription by two distal enhancers, E1 and E2. Characterization of …

Novel Oncolytic Herpesviruses For Breast Cancer Treatment, Anna Israyelyan

LSU Doctoral Dissertations

Oncolytic herpes simplex virus type-1 (HSV-1) has shown great potential as an effective agent for cancer therapy ¨C oncolytic virotherapy. To enhance oncolytic capabilities of previously reported agents, new oncolytic and fusogenic HSV-1 OncSyn and OncdSyn viruses were constructed based on wild type HSV-1 (F) strain. To provide for safety and tumor selectivity, the viruses carried a large deletion including one of the two ¦Ã134.5 genes. The ¦Ã134.5 gene, a major neurovirulence factor, was replaced by a gene cassette constitutively expressing the red fluorescent protein. Homologous recombination was utilized to transfer the fusogenic gBsyn3 mutation to the viral genome to …

Language Learning Through Storybook Reading In Headstart, Patricia Minnis Brazier-Carter

LSU Doctoral Dissertations

The purpose of this study is to explore whether storybooks designed to elicit talk about letters and sounds, termed "alphabet-storybooks" will generate more print referencing behaviors from Head Start teachers than traditional storybooks, and if there is a concomitant positive impact on the learning of the children in these classrooms. In addition, the meaning reference behaviors of adults and impact on children also will be measured to determine if meaning is sacrificed at the expense of print referencing.

A Qualitative Study Comparing Faculty's Perceptions Of Factors Affecting Successful Tenure Attainment In Nursing And Professional Fields Versus Traditional Disciplines, Marie Ann Cueman

Seton Hall University Dissertations and Theses (ETDs)

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Maldi Mass Spectrometry Imaging For The Discovery Of Prostate Carcinoma Biomarkers, Lisa Harris Cazares

Theses and Dissertations in Biomedical Sciences

The elucidation of new biological markers of prostate cancer (PCa) should aid in the detection, and prognosis of this disease. Diagnostic decision making by pathologists in prostate cancer is highly dependent on tissue morphology. The ability to localize disease-specific molecular changes in tissue would help improve this critical pathology decision making process. Direct profiling of proteins in tissue sections using MALDI imaging mass spectrometry (MALDI-IMS) has the power to link molecular detail to morphological and pathological changes, enhancing the ability to identify candidates for new specific biomarkers. However, critical questions remain regarding the integration of this technique with clinical decision …

A Study Of Compliance In Aged Care Facilities With Regards To Australian Standards 1851:2006 Maintenance Of Fire Protection Systems And Equipment Section 17, Robert Doleman

Theses : Honours

The management of risk within a nursing home environment is widely viewed as an undertaking perfom1ed by the owners or managers of nursing homes. The residents of these homes are reliant upon the owners and managers to keep them safe, due in part to a traditional belief that they are the experts and have a greater understanding of risk. To establish risk it is first a requirement to have an understanding of levels of risk and risk management techniques. Risk appreciation is often influenced by heuristic representativeness, as well as social and cultural influences. The higher level of risk within …

Is Enough Really Enough? : Evaluation Of An Alcohol Awareness Campaign At Ecu Joondalup, Marissa Macdonald

Theses : Honours

Australian young adults aged 17-25 years old attending university are more likely to drink at levels which put themselves at risk of both short and long term alcohol-related harm. University settings are an appropriate place to target university students with alcohol education or awareness-raising campaigns. Australian research on this topic is relatively limited. This mixed methods study involved two phases. The first phase quantitatively evaluated the impact of the 'Enough is Enough' campaign, implemented by the North Metropolitan Community Drug Service Team at ECU Joondalup, on students' awareness of the consequences of excessive alcohol use and perceived acceptability of drunkenness. …

Knowledge And Perceptions About Hepatitis C Among Police Undertaking Training At The Western Australia Police Academy, Cerissa Papanastasiou

Theses : Honours

Hepatitis C (HCV) is a significant health issue in Australia with approximately 90% of new cases attributed to injecting drug use (IDU). With no vaccination for this infection it is important that preventive methods are utilised to reduce the likelihood of it being transmitted from the IDU community into the wider community. Research has suggested that people's beliefs, which are influenced by the knowledge they have, play an important role in influencing the action people take in protecting and promoting their health. While there are numerous studies which have measured the HCV-related knowledge and perceptions of other professions in the …

Evaluation Of A Community Radio Station In Tulikup, Bali: Indonesia, Dane Anthony Waters

Theses : Honours

Community-oriented radio can be a valuable tool to mobilise communities and contribute to making positive social changes throughout the world (Dagron, 2001). Heartline Bali FM is a community-oriented radio station, which since development, has sought to positively impact the people within the community it serves. Located in the rural Balinese village of Tulikup, Indonesia, the station has responded practically to the health and social needs of the community through radio and other social development strategies since its establishment in 2003. In 2004, a base-line needs assessment was conducted within the village to help inform the radio station of the health …

The Benefits Of Pet Ownership For Single Adults In Midlife, Lauren Mcgillivray

Theses : Honours

Pets are shown to enhance quality of life through support and companionship. Midlife is a time where pets may be most valuable, since it is a time that involves critical changes to intimate relationships, roles and status. In this article a critical review of the literature on midlife development and demographic trends was carried out. Further, the psychological literature on human-pet relationships was reviewed and integrated with midlife research. Evidence for the psychological and physical benefits of pets is examined and the implications and potential benefits for middle aged adults are discussed. Findings suggest that pets may help to reduce …

Analysis Of Residual Solvents In Pharmaceuticals By Comprehensive Two-Dimensional Gas Chromatography, Cristina Marie Crimi

Seton Hall University Dissertations and Theses (ETDs)

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The Phenomenon Of Amoralism: An Investigation Of The Cognitive And Emotive Roots, Andrei G. Zavaliy

Dissertations, Theses, and Capstone Projects

An amoralist is defined as a person who rejects the claims of moral reasons to special authority, and systematically acts without regard to the generally accepted moral standards. A psychopath can be seen as a paradigm case of an extreme amoralist, although the less severe cases of selective amoralists are considered. The research into the typical behavioral pattern, motivational structure, and the value system of psychopaths can shed light on at least three aspects related to the analysis of the moral agency. First, it can help elucidating the emotive and cognitive conditions necessary for moral performance. Secondly, it can provide …

Development Of Lexical Tone Production In Disyllabic Words By 2- To 6-Year-Old Mandarin-Speaking Children, Puisan Wong

Dissertations, Theses, and Capstone Projects

This study investigated children's development in the production of Mandarin lexical tones in familiar disyllabic words and tested the hypothesis that disyllabic tone contours with more complex fundamental frequency contours are more difficult for children to produce. Participants were forty-four 2- to 6-year-old monolingual Mandarin-speaking children and 12 mothers. Their disyllabic tone productions were elicited by picture naming and low-pass filtered to eliminate lexical information while retaining the fundamental frequency contours. Three Mandarin-speaking judges listened to the filtered stimuli, and categorized the children's and adult's disyllabic tones. Acoustic analysis was performed on selected accurate child and adult productions and on …

Quantifiying The Depth Of Oral Sedation Using Bispectral Index Monitoring, John Flowers

Theses and Dissertations

Purpose: To determine whether Bispectral Index Monitoring is an effective tool for quantifying sedation depth after the administration of oral drug regimens in children.Methods: This retrospective study reviewed the charts of 75 children who received oral conscious sedation for dental treatment. Data collected from the chart included; 1) BIS values at 5 minute intervals and at five critical events: pre-operative, local anesthesia delivery, rubber dam placement (if utilized), during operative treatment, and postoperatively, 2) behavior ratings at the five critical events and an overall behavior assessment, 3) treatment data, and 4) demographic data. Results: The mean BIS value for orally …

Enzymology And Molecular Biology Of Bile Acid 7alpha- And 7beta- Dehydroxylation By The Intestinal Bacteria Clostridium Scindens And Clostridium Hylemonae, Jason Michael Ridlon

Theses and Dissertations

The collective microbial genomes within our gut(microbiome) represent a powerful metabolic force, leading many authors to call our GI flora an "organ within an organ", and the metagenomic sequencing of our microbiome, "the second human genome project". Bile acids, endogenously produced by the host liver, represent both a strong selective pressure for potential colonizers, aswell as substrates for microbial metabolism. Indeed, microbes have evolved enzymes to deconjugate bile salts, epimerize bile acid hydroxyl groups, and 7alpha-dehydroxylateprimary bile acids. The products of microbial 7alpha-dehydroxylation, secondary bile acids, are suggested by numerous lines of evidence to be involved in promoting colon carcinogenesis. …

Investigation Of Inosine And Hypoxanthine As Biomarkers Of Cardiac Ischemia In Plasma Of Non-Traumatic Chest Pain Patients And A Rapid Analytical System For Assessment, Don E. Farthing

Theses and Dissertations

Each year in the U.S., approximately 7-8 million patients with non-traumatic chest pain visit hospital emergency departments (ED) for medical evaluation. It is estimated that approximately 2-5% of these patients are experiencing acute cardiac ischemia, but due to the shortcomings of current test methods, they are incorrectly diagnosed and discharged without appropriate treatment provided, thus leading to poor patient outcome and potential medical malpractice litigation.The goals of this research were to evaluate plasma samples for potential biomarker(s) of acute cardiac ischemia prior to heart tissue necrosis, and to ultimately develop a rapid method for detection of the potential biomarker(s) in …

Effects Of Smoking And Gender On Tetrahydroisoquinolines And Beta-Carbolines In A Healthy Population And During Alcohol Detoxification, Satjit Singh Brar

Theses and Dissertations

The purpose of this investigation was to evaluate the effects of smoking and gender on 1) tetrahydroisoquinolines (TIQs) and beta-carbolines (BCs) in a population of healthy subjects and 2) TIQs in an alcohol-dependent population undergoing in-patient detoxification. Comparison in plasma TIQs between the populations was additionally conducted. To support the clinical investigations, a HPLC-FD method was developed and validated to assess plasma concentrations of BCs, harman and norharman, while a HPLC-ESI-MS/MS method was validated to quantify the TIQs, R/S-salsolinol along with dopamine. Forty-one young volunteers were recruited including 19 nonsmokers (NS), 11 light smokers (LS) and 11 heavy smokers (HS), …

Gene Therapy Using Tet-Repressor System To Modulate Prostate Tumor Microenvironment, Nazita Yousefieh

Theses and Dissertations in Biomedical Sciences

Prostate cancer is the most commonly diagnosed malignancy in men in the United States and is projected to be the third most frequent cause of male cancer-related deaths in 2007 after lung and skin cancers. The initial treatment for prostate cancer at early stages is prostatectomy or radiation, which usually is curative. However, approximately 20% of patients are not cured by such treatments and their cancer recurs, sometimes with long latencies. In other patients prostate cancer is diagnosed only after the cancer has metastasized and there are no effective therapies at this stage. Therefore immunotherapy seems to be a promising …

Modeling Physical Activity In Working Adults: How Suitable Is The Expanded Parallel Process Model?, Adwoa B-H-Sam

Health Services Research Dissertations

This study is an assessment of the usefulness of the Expanded Parallel Process Model in predicting health enhancing physical activity as an outcome variable. The theory is tested in the context of risk for coronary heart disease and involves secondary analyses of a dataset from a group of working adults. These individuals had elected first to participate in a health plan ‘Quality Improvement Study’ and were then randomly selected to receive an intervention program designed to get people to be more active.

Data on self-reported demographics, physical activity levels, health status characteristics and perceptions measured on a Likert-type scale known …

Population Based Estimates Of Medial Ulnar Collateral Ligament Injury, Samantha Lynne Sweet

Dissertations and Theses @ UNI

Injuries to the elbow are common among overhead throwers, especially in baseball players. There has been speculation that medial ulnar collateral ligament (MUCL) injuries have been increasing over the past fifteen years, however, population based estimates of MUCL injuries currently do not exist. The purpose of this study was to determine MUCL injury incidence rates derived from the National Center for Health Statistics over a three-year period. Non-identifiable, aggregate data provided by the National Center for Health Statistics were used in this study. The two main databases utilized were the NAMCS and the NHAMCS. Injury data from 2003 - 2005 …

Validation Of Physical Activity As A Measure Of Shoulder Dysfunction, Lindsey Kae Alderson

Dissertations and Theses @ UNI

The use of physical activity measures has been used in a variety of populations with various diseases and disabilities. The use of physical activity measures has shown known-group differences in populations with neurological disease, stroke patients, and lower extremity dysfunction. Physical activity measures have been used to show health differences, recovery, and disease progression and regression. The purpose of this project was to examine if physical activity are affected by isolated upper extremity shoulder injuries which then may be used as a functional outcome measure. This study was a non-experimental, observational, matched-pair design. A total of fourteen participants composed two …

Comparing The Effects Of Sung Versus Spoken Lyrics On Speech And Language Acquisition In Late-Talking Toddlers, Chelsea Ki Sook Clock Bell

Dissertations and Theses @ UNI

The purpose of this study was to explore the use of two intervention approaches with children who are delayed in their development of expressive language (i.e. "late talkers"). Identification and intervention for late talkers is often controversial. This study examined whether music therapy has an equal or greater effect on speech and language acquisition in two toddlers with late-developing speech and expressive language when compared to a literacy-based intervention involving storybook reading. The use of storybook reading in speech and language therapy has been examined and found successful when used with children with communication disorders. However additional research is needed …

Aging Effects On The Transcription Of Differentially Impaired Dysarthric Speech, Molly Anne Duggan

Dissertations and Theses @ UNI

Thirty participants transcribed 60 words and 30 sentences spoken by persons with dysarthria. Participants, all aged 65 and older were divided into three age groups: Young-Old, Middle-Old, and Old-Old. Each group was comprised of 10 participants. Stimuli were recorded by two male speakers with differing severity levels of dysarthria. Results suggested age did affect the transcription scores, as the Young-Old participants were able to transcribe words and sentences with greater accuracy than the Old-Old participants. The severity of the dysarthric speaker also affected the accuracy of participants in transcribing their words and sentences. Utterances produced by the speaker with mild …

Application Of The Interactional Model Of Cultural Diversity To Identify Diversity Climate Factors Associated With Organizational Effectiveness In Accredited U.S. Physical Therapist Education Programs, Elizabeth Francis Giles

Health Services Research Dissertations

Accredited U.S. physical therapist education programs are responsible for the preparation of its graduates to provide culturally sensitive care to meet the physical therapy needs of an increasingly diverse population. While the importance of workforce diversity has been articulated, the effect of diversity climate on organizational effectiveness within accredited U.S. physical therapist education programs has not been described. The purpose of this study was to evaluate the effectiveness of the Interactional Model of Cultural Diversity (IMCD, Cox, 1993) as a theoretical framework to identify diversity climate factors associated with organizational effectiveness in accredited U.S. physical therapist education programs. A descriptive, …