Medicine and Health Sciences Commons^™

Body Type And Perceived Physical Competence In College Female Dancers, Brenna Marie Vogel

Dissertations and Theses @ UNI

The relationship between body type and perceived physical competence was determined among college female company dancers. Participants were from one of four technique based dance companies at a midwestern university. They were questioned as to their perceived physical competence in seven different styles of dance, all of which had been offered at the selected university over the previous academic year. Body type was calculated using both the Body Mass Index Scale and the Body Composition Analyzer, which is a bioelectrical impedance analysis of one's body fat percentage, total body water, and body weight. A total of 44 participants took part …

Willingness To Influence Indication-Based Off-Label Prescribing: An Investigation Of Hospital Pharmacists, Ram Sankar Basak

Electronic Theses and Dissertations

Off-label prescribing is a comand legal practice in the United States. However, off-label prescribing occurs oftentimes with inadequate evidence of effectiveness. Such practice, especially when prescribing for disease conditions different from approved clinical indications (indication-based off-label prescribing), brings about controversy and raises different issues with various stakeholders. Although indication-based off-label prescribing offers advantages in terms of providing innovative therapy, it raises concerns because the safety and efficacy of such use may not be evaluated adequately. Thus, the objective of the study was to examine whether pharmacists are willing to influence physicians while evaluating an indication-based off-label medication order. Based on …

Type 2 Diabetes In Children: Estimates Of Epidemiology, Quality Of Care, Costs And Resource Utilization In A Medicaid Population, Vennela Thumula

Electronic Theses and Dissertations

Objective: the primary goal of this study was to assess the current state of diabetes, specifically type 2 diabetes in Mississippi Medicaid enrolled pediatric population. Background: Diabetes is the most prevalent pediatric chronic condition. Recent trends indicate that type 2 diabetes in children is increasing. Epidemiology estimates of type 2 diabetes in children and adolescents are limited. Quality of care and their health care utilization estimates are not available. Methods: 2002 - 2004 Mississippi Medicaid claims data were used for this study. A combination of ICD-9 codes (250.0x - 250.9x, where x=0 or 2) and/or oral hypoglycemic (OHG) drug use …

Fungi-Derived Natural Products With Binding Affinities For Human Opioid Or Cannabinoid Receptors, Jiangtao Gao

Electronic Theses and Dissertations

Both opioid and cannabinoid receptors belong to the large superfamily of GPCRs and play an important role in a variety of processes including pain, craving, neurodegeneration, metabolic regulation, anxiety and immune function. Therefore, recent advances and discoveries in opioid and cannabinoid receptors have paved the way for a very exciting future for opioid and cannabinoid receptors-based therapies to potentially treat a variety of conditions. However, the growing realizations of the complexity of these two receptors regulation in physiological and pathological conditions have discouraged the development of new therapeutics. So, it is important for us to identify new chemical scaffolds which …

Effect Of Exogenous Leptin On Thrombotic And Metabolic Profiles Of Fvb/B6 Lipodystrophic Mice, Hoda Chaouki Kadouh

Wayne State University Theses

Lipodystrophy caused by fat deficiency contributes to metabolic disease for which several treatment modalities have been implemented, with leptin therapy being the most effective to date. In addition to playing a role in energy homeostasis and metabolism, leptin was also shown to play a pro-thrombotic role in mice. This role was not examined in fatless mice, neither was thrombosis measured. The AZIP/F-1 (FVB) lipodystrophic mouse appeared to have a prolonged arterial occlusion time (p〈0.05) in a trial done in our lab, with clotting factors being normal. The present study was designed to observe the thrombotic and metabolic characteristics of fatless …

The Experience Of Chronic Pain As Described By African American Indigent Adults Attending An Urban Primary Care Clinic, Jamie Alexandra Crawley

Wayne State University Dissertations

Background: Inadequate chronic pain control has far-reaching implications including costs for missed time at work; utilization of health care resources and reduced quality of life. People at highest risk for inadequate pain control include indigent adults and minorities. Newman's theory health as expanding consciousness views the chronic pain experience as a life pattern within health. Qualitatively examining chronic pain from participants' perspectives may improve chronic pain care.

Purpose: The purpose of this study was to examine the experiences of chronic pain as described by African American indigent adults attending an urban, primary care clinic.

Methods: 13- participants (7 men and …

The Role Of Extracellular Matrix Proteins, Biglycan And Fibromodulin, In Temporomandibular Joint Osteoarthritis, Mildred Christine Embree

MUSC Theses and Dissertations

Temporomandibular joint osteoarthritis (TMJ OA) is a degenerative joint disease, which ultimately results in severe pain, permanent cartilage destruction, and TMJ dysfunction. The extracellular matrix (ECM) micro-environment is critical for maintaining the TMJ mandibular condylar cartilage tissue integrity and is important for regulating chondrocyte activity. The small leucine-rich repeat proteoglycans (SLRPs) are a family of ECM proteins that are highly expressed in cartilage and bone. The goals of this study were to determine the role of two members of the SLRP family, biglycan (Bgn) and fibromodulin (Fmod), in the development of TMJ OA pathology and to identify the early cellular …

Evidence Based Practices For Sensory Stimulation Seeking Impulsive Diagnosis, Sheena Gasner

All Graduate Theses, Dissertations, and Other Capstone Projects

The purpose of this project is to identify evidence based practices that can be used in the treatment of Sensory Stimulation Seeking Impulsive Disorder (430.0). Identification of these practices will more effectively meet the therapeutic needs of the children diagnosed with this disorder.

Grades In Prerequisite Courses As Predictors Of Success In A Nursing Program, Elaine Zeilke Foster

Dissertations

Problem: The U.S. Bureau of Labor Statistics forecast that by 2016 more than one million new and replacement nurses will be needed to fill jobs in the health care field . In order to meet the medical needs of a changing society, schools of nursing must continue to educate and graduate significant numbers of nurses. This may be done by increasing the success rates of those who are admitted in nursing programs. Success rate is thought to be related to admission criteria used to admit students which, in turn, may reduce attrition rate, which is between 20 to 40% in …

The Lived Experience: Pulmonary Arterial Hypertension And Intravenous Prostaglandin Therapy, Phyllis D. Boone

Masters Theses

A descriptive phenomenological study was proposed to obtain a subjective description of the experience of living with intravenous prostaglandin treatment for pulmonary arterial hypertension. It was intended to determine what kinds of elements are common to the experience with study participants, to develop an aggregate structure of the experience from the individual descriptions of it, and add to what is now known about this phenomenon. It was anticipated that the stories told by the participants could help to determine how nurses can assist future patients to live optimally within the confines of a palliative treatment for this incurable illness.

Unfortunately, …

Effects Of Chlorpromazine On Feeding And Wheel Running On Rats With Acute Wheel Access, Graham Gregory Parfeniuk

Theses and Dissertations (Comprehensive)

Anorexia Nervosa (AN) is characterized by a self-imposed starvation and is often accompanied by excessive exercise that results in severe malnutrition and sometimes death. Behavioural and pharmacological treatments of AN need to be improved. In rats, acute 3 h daytime wheel access suppresses ad lib feeding over the subsequent night relative to no wheel controls, a phenomenon that has been suggested as an animal model of AN. This acute wheel induced feeding suppression (WIFS), can be induced reliably when rats are given limited wheel access exposure during the light cycle (Lattanzio & Eikelboom, 2003). The acute WIFS is useful because …

Knowledge And Awareness About H1n1 Influenza (Swine Flu) Among University Students, Suneel Kumar Parvathareddy

All Graduate Theses, Dissertations, and Other Capstone Projects

H1N1 influenza (Swine influenza or Swine flu) is a respiratory disease of pigs caused by type A influenza virus that regularly causes outbreaks of influenza in pigs. Worldwide, as of October 17, 2009, there have been more than 414,000 laboratory confirmed cases of pandemic influenza H1N1 2009 and nearly 5000 deaths. The 2009 flu pandemic is a global outbreak of a new strain of influenza A virus subtype H1N1 and was first identified April 2009 in Mexico. On June 11, 2009, WHO declared the H1N1 outbreak as a pandemic. Worldwide, as of April 11, 2010, more than 214 countries and …

Anti-Nogo-A Immunotherapy Facilitation Of Environmental Enrichment's Effects On Recovery From Stroke In The Aged Rat, Sarah Jane Hein

Master's Theses

Stroke and traumatic brain injury are devastating disorders that often lead to permanent neurologic deficits, with few available treatment options once injury has occurred. In previous work, Anti-Nogo-A immunotherapy has been shown to neutralize the neurite inhibitory protein, Nogo-A, and to promote neuronal plasticity and improve functional recovery after stroke in the rat. Furthermore, other reports have demonstrated that environmental enrichment improves functional recovery in rodents following stroke. Our previous work demonstrated that anti-Nogo-A immunotherapy also helps promote cortical plasticity in the rodent. In the current project, we examined two methods to promote recovery after brain injury, a stroke model …

Depressive Symptoms In Women Being Screened For Cardiovascular Disease Risk, Suzanne Marie Savoy

Dissertations

Background: Depressive symptomology is an independent risk factor for cardiovascular disease. Over 15% of persons with cardiovascular disease have depressive symptoms, and women are twice as likely to experience these symptoms as men. Depressive symptoms in women “ at risk ” for cardiovascular disease has not been well studied.

Purpose: This study investigated the relationship between depressive symptoms, health-promoting lifestyle behaviors, heart disease risk awareness, cardiac risk, and quality of life in women at risk for cardiovascular disease. Whether the effect of depressive symptoms on quality of life was mediated by cardiac risk and/or health-promoting lifestyle behaviors was also examined. …

Investigation Of Working Memory Across Behavioral And Executive Function Variables In Adolescents With Emotional Disturbance, Eleazar Cruz Eusebio

PCOM Psychology Dissertations

Newer insights into working memory may have important implications for understanding varying cognitive abilities in adolescents and their corresponding degrees of success and efforts to accomplish real-world goals. It is important to investigate the construct of working memory in relation to academic, behavioral, and emotional success at school for students classified with an Emotionally Disturbance (ED). In the educational system, students are classified as ED, based upon IDEA regulations present within a multiplicity of these cognitive, behavioral, socio-emotional, and academic difficulties. The associated cognitive deficits often involve poor working memory skills thought to be related to frontal lobe processes. Considering …

The Impact Of Pre-Operative Mupirocin Prophylaxis On Surgical Site Infections In Same-Day Admission Open Heart Patients, Joanna Gerry

Electronic Theses and Dissertations

The CDC estimates that one in 20 patients admitted to the hospital is a carrier of methicillin-resistant Staphylococcus aureus (MRSA). Staphylococci are commonly found on the skin and mucous membranes within the anterior nares, which provides the principle reservoir for this organism. These organisms can go on to cause surgical site infections in hospitalized patients. Mupirocin is an effective topical medication used to eliminate nasal carriage of Staphylococcus aureus (S. aureus). Based on Level A evidence, the 2007 Society of Thoracic Surgeons has made a Class I recommendation for the use of mupirocin for all patients undergoing cardiac surgery in …

Prevalence Of And Risk Factors For Intraoperative Non-Euglycemia Events In Premature Neonates >2500 Grams, Zulay Ritrosky

Electronic Theses and Dissertations

This study examined the rates and risks of premature neonates >2500grams developing intraoperative non-euglycemia events (IONEE). A retrospective chart review of 26 premature neonates >2500 grams who underwent surgical procedures between January 1 and December 31, 2009 was conducted. Statistical analysis was done using Chi square and t-tests. Ten of the 26 subjects (38%) experienced an IONEE. Hyperglycemia was the primary IONEE that was noted in the neonates. (Mean: 143.19; sd: 56.041) Length of surgery was significantly longer in those premature neonates with IONEE than those with euglycemia (71.7 0± 27.03 vs. 45.62 ± 17.98 minutes). All IONEE subjects received …

Patterned Cell Cultures For High Throughput Studies Of Cell Electrophysiology And Drug Screening Applications, Anupama Natarajan

Electronic Theses and Dissertations

Over the last decade, the field of tissue and bio-engineering has seen an increase in the development of in vitro high-throughput hybrid systems that can be used to understand cell function and behavior at the cellular and tissue levels. These tools would have a wide array of applications including for implants, drug discovery, and toxicology, as well as for studying cell developmental behavior and as disease models. Currently, there are a limited number of efficient, functional drug screening assays in the pharmacology industry and studies of cell-surface interactions are complicated and invasive. Most cell physiology studies are performed using conventional …

Studies On A Novel Human Cardiospecific Transcription Factor And Its Involvement In Omi/Htra2 Mediated Cell Death, Meenakshi Puthucode Balakrishnan

Electronic Theses and Dissertations

Omi/HtrA2 is a mitochondrial serine protease that is known to translocate to the cytoplasm upon induction of apoptosis and to activate caspase-dependent and caspase-independent cell death. The molecular mechanism of Omi/HtrA2's function is not clear but involves degradation of specific substrates. These substrates include cytoplasmic, mitochondrial, as well as nuclear proteins. We have isolated a new Omi/HtrA2 interactor, the THAP5 protein. THAP5 is a fifth member of a large family of transcription factors that are involved in cell proliferation, apoptosis, cell cycle control, chromosome segregation, chromatin modification and transcriptional regulation. THAP5 is an approximately 50kDa nuclear protein, with a restricted …

Recommendation For The Prevention Of Nursing Burnout, Lindsey N. Kimmerling

HIM 1990-2015

Burnout is a bio-psychosocial response related to chronic stress in the work environment (Hertel, 2009). In nursing, burnout can affect the work environment, coworker relationships, and patient care. It can lead to patient dissatisfaction, nurse dissatisfaction and even patient harm. With the nursing shortage predicted to increase to over 1,000,000 by the year 2012, it is of vital importance that methods to reduce and prevent burnout be researched and implemented in order to retain nurses and ensure the delivery of safe and effective care. The purpose of this literature review was to determine what knowledge base already existed about the …

Retrospective Analysis Of Screening Patterns In Cirrhotic Patients With Heptocellular Carcinoma, Shelly-Ann Scott-Castell

Electronic Theses and Dissertations

The incidence of hepatocellular carcinoma (HCC) in cirrhotic patients is increasing worldwide. Cirrhotic patients are recommended by the American Association for the Study of Liver Disease (AASLD) to receive HCC screening and surveillance every 6 months to a year. The purpose of this study was to identify the current screening and surveillance patterns for cirrhotic patients with HCC in clinical practice. Hepatocellular carcinoma can be detected by radiological studies in addition to laboratory testing. It is important to implement the AASLD screening guidelines, as early identification might decrease the mortality rate of patients with cirrhosis and HCC. The research question …

Using Modeling And Simulation To Evaluate Disease Control Measures, Tracy Atkins

Electronic Theses and Dissertations

This dissertation introduced several issues concerning the analysis of diseases by showing how modeling and simulation could be used to assist in creating health policy by estimating the effects of such policies. The first question posed was how would education, vaccination and a combination of these two programs effect the possible outbreak of meningitis on a college campus. After creating a model representative of the transmission dynamics of meningitis and establishing parameter values characteristic of the University of Central Florida main campus, the results of a deterministic model were presented in several forms. The result of this model was the …

The Effect Of Combat Exercises On Cardiovascular Response: An Exploratory Study, Melisa Gantt

Electronic Theses and Dissertations

PURPOSE: Hypertension (HTN) affects one in every three adults in the United States. Often associated with the older population, this silent killer has emerged in an unsuspecting group, young military soldiers. With the rapid succession of multiple deployments, long intervals between blood pressure (BP) assessments, and the absence of cardiovascular (CV) measures during the pre and post deployment health screenings; soldiers may be at higher risk for HTN than their civilian counterparts of the same age. The purpose of this study was to explore real-time continuous CV measures of soldiers before, during, and after exposure to a simulated combat stressor …

The Role Of The Arts Toward Healing Trauma And Building Resilience In The Palestinian Community, Yousef Al-Ajarma

Expressive Therapies Dissertations

This study has investigated the sources of resilience in a sample of Palestinians who experienced the first Intifada and are now studying in the United States. The study found that family and community support, the pursuit of an education, and participation in artistic activities all contribute to individual resilience among Palestinians. In addition, political awareness and activity are another source of resilience, because they help individuals living under the Occupation to find meaning in their life and make sense of their struggles. Currently, young people in Palestine are at risk of developing psychological trauma from exposure to the violence of …

Phenomenology Of Embodied Dreamwork With Puerto Rican Women: A Dissertation, Lourdes F. Brache-Tabar

Expressive Therapies Dissertations

The author investigated the experience of embodied dreamwork. Participants were eight Puerto Rican women who were chronically ill, of low socioeconomic status, who lived in Boston. The data were analyzed using transcendental phenomenology. Each participant engaged in one embodied dreamwork–unstructured interview session lasting approximately 1.5 hours. In addition, each participant drew a picture of how she felt after the dreamwork interview. This snowball, purposive sample gave detailed information about how they experienced embodied dreamwork. The participants’ statements were grouped into themes: (a) sense of place—environment, surroundings, spatiality; (b) the players—self, others; (c) plot; (d) in the sea of emotions—naming affective …

Evaluating The Target Pipeline In A Pharmaceutical Acquisition, Daniel Vass

Business and Economics Honors Papers

Many firms in the pharmaceutical industry turn to acquisitions when faced with gaps in their drug development pipelines and patent expirations as an alternative to making long-term investments in internal research and development. Investors are generally negative on this strategy, and upon the announcement of a pharmaceutical acquisition the stock of the acquiring firm often drops. This decline in share price creates an opportunity for the investor who can identify the characteristics of a target firm that increase the probability that the transaction will ultimately be a success, as measured by the subsequent appreciation in the acquirer's stock. It is …

Vegetarians And Vegans In Kentucky, Danita Martha Hines

University of Kentucky Master's Theses

Kentucky has a health crisis and most of the causes can be linked to diet, smoking and physical activity. Vegetarian and vegan diets have numerous benefits for many diet related health problems such as obesity, heart disease, Type 2 diabetes and certain cancers. There has been limited research on vegetarians and vegans in the United States and none in Kentucky. This study used an anonymous electronic survey to examine the different characteristics, behaviors, experiences and opinions of adult vegetarians and vegans in Kentucky. Results were compared to statistical data reported on the general population of Kentucky. Calculated body mass index …

Dietitians’ Use And Perceptions Of Nutrition Screening Tools For The Older Adult, Sarah Ross Small

University of Kentucky Master's Theses

Malnutrition is a significant issue affecting the health of many adults over the age of 65. Screening for malnutrition in this population can help identify those in need of a complete nutritional assessment. Many screening tools have been developed to aid healthcare team members in identifying those at risk for malnutrition. A population of dietitians with a focus in older adult nutrition was surveyed to determine dietitians’ perceptions and use of screening tools for the older adult. The results of the study showed many dietitians did not use validated screening tools at their place of work and were not confident …

Examining The Impact Of California's Medical Marijuana Program On Public Health, John C. Lamb

CMC Senior Theses

The debate surrounding marijuana legalization has increased its popularity in recent years, as the state of California seriously considers the complete legalization of the substance for those ages 21 and over. This would make California the first government in recorded history to regulate the cultivation and sale of marijuana on a commercial level. Advocates back the economic positives concerning high tax revenues, but those opposed argue that the dangers associated with public health greatly outweigh any monetary gain. The present study attempts to reveal the possible public health concerns, even potential benefits, caused by marijuana use and its distribution. Specifically, …

From Disco To Electronic Music: Following The Evolution Of Dance Culture Through Music Genres, Venues, Laws, And Drugs., Ambrose Colombo

CMC Senior Theses

Electronic dance music is a genre that has been long in the making. Starting with disco in the 1970s, dance culture genres evolved into house, acid house, techno, garage, 2-step, hardcore, gabba, san frandisco, electro, and many others. This paper studies the transformation of electronic sound, and the contributing/impeding factors involved. Drug use is heavily related to the creation and enjoyment of music, and features prominently in the history of dance culture. Starting with the use of acid in the 1960s and progressing to the use of acid, Quaaludes, poppers, speed in the 1970s, with MDA featured in clubs toward …