Medicine and Health Sciences Commons^™

On Death And Disease: How Physicians’ Perspectives Compare Across Specialties Through Written Work, Stephanie Anne C. Alkonga

Honors Capstones

Narrative medicine is a tool that the medical field is increasingly utilizing to cultivate patient-centered and culturally competent doctors and to reflect on lived experiences through texts that focus on psychosocial best practices. This study aims to examine the language used in physician-written works that address how physicians in different medical specialties treat the aging and the terminally ill, and how they view the deceased. Qualitative data guided by thematic questions will primarily be used in the analysis and comparison of these texts’ tone, rhetoric, diction, and similar literary devices to uncover if certain patterns arise across such specialties. Findings …

A Comparative Analysis Of Nf-Κb1 Gene Regulatory Sequence Methylation In Normotensive And Hypertensive Kenyans, Aaryan Barlas Piracha

Honors Theses

Accounting for the majority of deaths worldwide, non-communicable diseases (NCDs) present the greatest health challenge of the twenty-first century. Specifically, cardiovascular diseases (CVDs) exceed all other NCDs in annual deaths and especially affect low- and middle-income countries (LMICs). Hypertension, being the primary risk factor for CVD, affects over 75% of adults in LMICs due to inadequate health care and preventative measures. Additionally, epigenetic modifications of DNA are important mechanisms that regulate gene expression; DNA methylation, in particular, affects cytosine residues in cytosine-phosphate-guanine (CpG) islands on regulatory sequences. Previous research in our laboratory analyzed percent methylation at 8 different CpG islands …

Pseudomonas Aeruginosa Exoenzyme Y Enzymatic Activity Inhibits Exoenzyme S-Induced Caspase Activation But Not Cytotoxicity In Pulmonary Microvascular Endothelial Cells, Connor Holm

Honors Theses

Pseudomonas aeruginosa (P. aeruginosa) is the most common cause of ventilator-associated pneumonia in intensive care unit patients. P. aeruginosa utilizes a type III secretion system that injects exoenzymes U, S, T, and/or Y into the host cell cytosol. A majority of clinically isolated P. aeruginosa strains express ExoY often in combination with ExoU and ExoT, or ExoS and ExoT. Host signaling mechanisms in response to intoxication with individual exoenzymes have been extensively studied, yet little is known about host cell response to co-intoxication. In this study, pulmonary microvascular endothelial cells (PMVECs) were infected with P. aeruginosa strains expressing different combinations …

Toxicity And Biodegradability Of Novel Boronium Vs Conventional Ammonium-Based Antimicrobial Compounds In Wastewater Treatment Systems, Noor Shalan

Honors Theses

Quaternary ammonium compounds (QACs) are highly effective as disinfectants, herbicides, and pesticides; thus, overuse causes elevated levels of residual toxicity in domestic and industrial wastewater. QACs can be toxic to essential bacteria breaking down pollutants in wastewater treatment plants (WWTPs) and can remain untreated in effluent, harming the environment, and contributing to antibiotic resistance, posing risks to human health. Novel boronium-based antimicrobial compounds have demonstrated efficacy in eliminating bacteria, fungi, and viruses. If the boronium compounds exhibit lower residual toxicity, they could offer a promising alternative to QACs. Because these compounds are still in development, their potential toxicity to the …

Comparing Online And In-Person Social Support And Its Effects On Suicidal Ideation, Alexander J. Potter

Honors Theses

According to the interpersonal theory of suicide, thwarted belonging and perceived burdensomeness are proximal causes of suicidal ideation (Van Orden et al., 2010). Studies show that a lack of social support can lead to higher levels of thwarted belonging and perceived burdensomeness (Sparks et al., 2023). This relationship between social support and suicidal ideation has been studied in the literature, but the relationship between online and in-person social support with suicidal ideation has not. The purpose of the current study is to examine the effects of in-person and online social support on different factors of the interpersonal theory of suicide. …

Preliminary Assessment For Quality Improvement Of Hypertension Management In Kenya, Shubhangi Singh

Honors Theses

Hypertension is a leading contributor to cardiovascular disease (CVD) morbidity and mortality worldwide, with a disproportionate burden in low- and middle-income countries (LMICs). Despite relatively low rates of common behavioral risk factors, the Kasigau region of Kenya experiences high prevalence of hypertension and hypertension-related complications. This study explores self-efficacy, health beliefs, and management behaviors among adults in Kasigau to provide pilot quality improvement data for providers and future intervention planning. A cross-sectional, randomized survey of 45 adults was conducted at the Bughuta Clinic in southeastern Kenya. Participants completed a five-question hypertension-specific, self-efficacy assessment and a health belief model-based survey, with …

Navigating Insulin Access For Pediatric Type 1 Diabetes: Caregivers' Experiences And Challenges, Ella Anderson

Doctoral Dissertations

Between 2012 and 2018, the annual 14% increase in insulin prices made Type 1 Diabetes (T1D) the most expensive chronic health condition, significantly raising out-of-pocket costs for uninsured or underinsured individuals in the United States (Hayes & Farmer, 2020; Willner et al., 2020). This study utilized a qualitative content analysis methodology to explore the challenges and experiences of parents with children diagnosed with T1D with accessing insulin for their child. Five participants from various areas of the United States responded to open-ended questions both in person and via Zoom. The analysis revealed three main themes: pragmatics of managing diabetic care, …

The Impact Of Hazardous Noise Levels On The Hearing Mechanism Of Marching Band Students, Margaret Westbrook

Honors Theses

Marching band participants are exposed to hazardous noise levels, and they are at risk of developing hearing loss. In this study, the impact of marching band noise on the hearing mechanism of marching band students was examined. Participants who were not in the marching band and were not exposed to noise were used as controls. Detailed case history and noise exposure history were collected using a noise exposure questionnaire (NEQ). The pure tone audiometry test was conducted to examine their hearing, distortion product otoacoustic emissions (DPOAEs) were recorded to examine the inner ear function, and auditory brainstem responses (ABR) were …

Lateral Violence Awareness In Nursing Students At The University Of Southern Mississippi, Aika Owens

Honors Theses

The purpose of this honors thesis was to obtain descriptive data about how nursing students at the University of Southern Mississippi School of Professional Nursing Practice perceive lateral violence in their clinical rotations and educational environments. This Honors thesis is significant to nursing because although lateral violence is a well-researched topic among scholars of nursing practice, there is little gathered data regarding lateral violence among nursing students, specifically at the University of Southern Mississippi. Nursing students are a vital population to examine because nursing students are often first exposed to lateral violence within a clinical setting, leading to early internalization …

Jump Strategy Changes In Collegiate Women Soccer Players, Madeline Klubertanz

Master's Theses

Countermovement jumps (CMJ) are often utilized to monitor athletes because of their sensitivity to neuromuscular fatigue, which can be seen through assessing jump strategies. The current literature has reported conflicting views on how jump performance is impacted over acute and longitudinal testing. This is likely due to insufficient analyses regarding the impact of fatigue on jump strategy. This study aimed to investigate how the integration of jump strategy metrics and single-subject analysis could provide a better representation of the presence of fatigue among collegiate women soccer players. Eighteen participants were utilized in this study. Participants were required to complete three …

Using Motivation Science To Understand And Overcome Common Psychological Barriers To Non-Native Language Learning In Beginner And Intermediate College Courses, Ahana Nagarkatti

College Honors Program

This project examined whether established findings from the motivation science literature could be successfully applied to increase non-native language learning outcomes and persistence among college students. Participants were enrolled in beginner and intermediate language courses at a small private college. The study was longitudinal and involved “diagnosing” and immediately implementing interventions to counter deficits experienced by individual students regarding six specific motivational antecedents: expectancies for success, utility value, costs, autonomy, belonging, and growth mindsets. Over the course of a semester, participants’ motivational experiences in these areas were measured and they then completed tailored “just-in-time” intervention activities designed to increase their …

Examining The Impact Of The Executive Healthcare Leadership Institute On Faculty Readiness To Lead, Blythe Eggleston

Graduate Theses and Dissertations

Americans living in rural communities face significantly poorer health outcomes compared to those in urban areas. Academic medical centers (AMCs), such as the University of Arkansas for Medical Sciences (UAMS), play a critical role in addressing these disparities by incorporating rural health improvement into their mission. UAMS has committed to mitigating adverse health outcomes through targeted initiatives. However, AMCs operate within highly complex environments, balancing their tripartite mission of teaching, research, and clinical care, which demands exceptional leadership. These institutions also face unique organizational and economic challenges, compounded by personal and professional pressures on faculty members. To enhance leadership capacity …

Optimum Volume Of Serious Fluid For The Detection Of Malignancy: A Systematic Review, Sarah Atieno Okech

Master of Medicine in Anatomic Pathology

No abstract provided.

The Lived Experience Of Women Who Have Experienced Intimate Partner Violence In Trinidad And Tobago, Lyris Antoinette Greenidge

Theses & Dissertations

Background: Intimate partner violence (IPV) is an increasing public health issue worldwide and is predominantly committed by males against females. One in every three women worldwide has experienced IPV (World Health Organization [WHO], 2024). The Pan American Health Organization studied IPV in 12 Latin American and Caribbean countries (Bott et al., 2019), and the Republic of Trinidad and Tobago was included. At the inception of this study in 2018, the prevalence and effect of IPV, though captured in the media by Fraser (2014) and others, were recognized as a widespread monumental problem in Trinidad and Tobago. However, it appeared to …

Development And Validation Of An Adolescent Sleep Algorithm For Pediatric Primary Care, Holly Hink

Doctoral Scholarly Projects & Capstones

Poor sleep quality is a common challenge for many adolescents due to various developmental, environmental, and social factors. Nearly half of all adolescents reported regularly experiencing sleep disruptions. Poor sleep quality among adolescents might have severe mental, emotional, and cognitive consequences including an increased risk for several psychiatric conditions, obesity, and poor academic performance. However, sleep disorders among this population frequently go unreported and are rarely screened during annual well-child exams with primary care providers. The purpose of this project was to develop an evidence-based sleep algorithm for pediatric primary care providers designed to improve screening and treatment of adolescent …

Assessing Correlation Of Dental Health And Appalachian Culture, Samantha G. Cheek

Honors Theses

Proper dental health is crucial for overall well-being, yet access to dental care remains a significant challenge in rural Appalachia. This study examines the relationship between Appalachian cultural identity, fatalistic beliefs, and dental health. Using survey data from 20 participants at dental offices in Chattanooga, Tennessee, the study assessed correlations between Appalachian identity, fatalism, and self-reported dental health. Results indicate a high prevalence of dental health issues (95% reported significant problems), with 70% lacking dental insurance. However, correlations between Appalachian identity, fatalism, and dental health were not statistically significant. Findings suggest that while cultural factors play a role in healthcare …

‭Prevalence Of Potentially Pathogenic Bacteria In Showers At A Long-Term Nursing Care Facility, Joseph Caleb Kulon

Honors Theses

Pathogenic bacteria on environmental surfaces in nursing homes may contribute to the‬ growing burden of healthcare-associated infections (HAIs), particularly as the U.S. population‬ ages and more individuals transition into long-term care. In this study, 70 swab samples were‬ collected from five community shower rooms at a nursing home over three sampling trips. Five‬ common shower surfaces were sampled: the floor drain, shower bench, faucet/valves, shower‬ curtain, and grab bars. Samples were processed in the UTC CIDC microbiology lab and‬ inoculated onto four selective and differential media: Hardy CHROM MRSA agar (for‬ methicillin-resistant‬‭ Staphylococcus aureus‬‭ [MRSA]‬‭ and‬‭ S. pseudintermedius‬‭ [SIM]), mannitol‬ …

Bacterial Contamination Of Wheelchairs In A Long-Term Rehabilitation Facility, Storm A. Welch

Honors Theses

The presence of bacterial contamination on wheelchair surfaces in long-term care facilities poses a significant risk to infection control and patient safety. This study aimed to assess the prevalence and diversity of bacterial species, including Staphylococcus aureus (SA), methicillin-resistant Staphylococcus aureus (MRSA), Staphylococcus epidermidis (SE), Pseudomonas spp., and enteric bacteria on five key components of wheelchairs at a local long-term care facility. A total of 320 swabs were collected from wheelchair components, including handles for pushing, armrests, seats, wheel handles, and tires. Samples were analyzed using selective culture media, and bacterial species were identified based on colony morphology. The results …

Evaluation Of Avenanthramide-A As A Skin Penetration Enhancer: In Vitro And In Vivo Testing On Permeation Of Magnesium Ascorbyl Phosphate And Diclofenac Sodium From Topical Gels, Darshil Dhiren Shah

Selected Full-Text Dissertations 2020-

Topical and transdermal drug delivery are favored to deliver active pharmaceutical ingredients directly to the skin as an alternative to oral administration for systemic effects. In either case, the active molecules must cross the stratum corneum and epidermis to reach the site of action. The stratum corneum serves as a primary barrier limiting compounds from fully penetrating the skin. Therefore, it is necessary to add penetration enhancers to topical formulations to enhance drug delivery through the skin. Often, penetration enhancers are also irritant to the skin. Earlier research in our pharmaceutical laboratory showed that an addition of colloidal oatmeal, produced …

Artificial Intelligence (Ai)-Assisted Cardiotoxicity Management In Lung Cancer Radiotherapy, Xinru Chen

Dissertations and Theses (Open Access)

Lung cancer remains one of the leading causes of cancer-related mortality worldwide, with radiation therapy being a cornerstone of treatment. However, radiation-induced cardiotoxicity has emerged as a significant long-term complication, impacting patient survival and quality of life. There is increasing evidence that post-radiotherapy cardiotoxicity is better indicated by cardiac substructure dose, compared with whole heart dose. Despite this, cardiac substructures are not routinely incorporated into clinical workflows due to the significant time and resource demands associated with manual segmentation. Moreover, the relationship between dose distribution in radiotherapy plans and radiation-induced cardiotoxicity remains incompletely understood. Therefore, the development of an automated …

Fc Gamma Receptors Facilitate Antigenic Modulation Of Lilrb4 And Function As Predictive Biomarkers In Acute Monocytic Leukemia, Joshua Morse

Dissertations and Theses (Open Access)

Acute monocytic leukemia (monocytic AML) is a subtype of AML marked by a proliferation of abnormal monoblasts. This subtype represents approximately 10% of AML cases. The prognosis of monocytic AML is poor, with a 5-year survival of ~30%. Most patients are diagnosed at an age when they are unlikely to survive first-line non-targeted cytotoxic chemotherapy as a bridge to hematopoietic stem cell transplant (HSCT). Even patients who achieve remission commonly relapse. This population of patients would greatly benefit from precision-targeted therapies but currently there are none approved for monocytic AML.

Leukocyte immunoglobulin-like receptor B4 (LILRB4) is an immune checkpoint expressed …

Expanding Inducible Epithelial Resistance Against Pneumonia: Novel Virus, Novel Receptor, Michael Longmire

Dissertations and Theses (Open Access)

Pneumonia is the leading infectious cause of death worldwide and presents a continuing risk among immunocompromised patients. Our work has been focused for many years on the phenomenon of inducible epithelial resistance, where activation of the innate immune response in the airway epithelium is necessary and sufficient to produce a pathogen-killing but self-protective environment to prevent severe disease. Inducible resistance is pathogen-agnostic and has been demonstrated against an array of respiratory infections. We achieve this using a combination of pattern recognition receptor agonists – Pam2CSK4 and ODN M362 being the current formulation – which produce synergistic levels of pathogen reduction …

Replication Of “Assessing The Student Nurses’ Knowledge Of Oral Health Care”, Heaven Mcnalty

Honors Theses

Oral health is an important part of overall health and well-being. In nursing care, maintaining good oral hygiene helps prevent infections, improves comfort, and supports nutrition especially in patients who are extremely sick, elderly, or unable to care for themselves. Nurses play a key role in assessing and promoting oral health as part of the daily care that they provide to patients. Even though oral health is important, it is often not emphasized enough in nursing education. Many nursing students may not get enough training or experience in this area, which can lead to gaps in their knowledge and confidence …

Joint Modelling Of Longitudinal Egfr Trajectory And Time To Acute Kidney Injury In Lung Transplant Patients, Samiha Zakir

Theses and Dissertations

Progressive declines in estimated glomerular filtration rate (eGFR) often precede acute kidney injury (AKI), yet the relationship between eGFR trends and AKI risk remains unclear. This study investigates longitudinal eGFR changes and their association with AKI in 459 lung transplant patients followed for up to 7 years (n = 6419). We applied a piecewise linear mixed-effects model to evaluate eGFR trajectories and a Cox proportional hazards model to assess time to AKI. A joint model was used to explore the interplay between longitudinal and survival processes. Key covariates included gender, age at transplantation, antibody-mediated rejection (AMR), and pre-transplant eGFR. Males …

Useful Measures Of Adult Attachment And Object Relations In Psychotherapy, Matilde A. Torallas Huerta

Dissertations

This is a literature review of objective and projective measures of attachment and object relations in adults, with the objective of reviewing outstanding research to identify the key factors for adult attachment assessment considered within attachment and object relations theories, what measures of adult attachment styles and dysfunction work best, and to provide key themes of assistance in the measurement of attachment and object relations in adult clients in psychotherapy. Theoretical foundations of attachment and object relations theory are reviewed as well as objective and projective instruments grouped by format. The 10 themes found to be useful in the assessment …

Highly Pathogenic Avian Influenza Outbreak Preparedness In The United States: A Scoping Review, Emma J. Gurley

Honors Theses

In order to gauge preparedness for an outbreak of highly pathogenic avian influenza (H5N1) in the United States, a scoping review of the current literature was conducted. This process involved (1) identifying the research question, (2) identifying studies relevant to the topic, (3) selecting studies for inclusion (4) charting the data, and (5) analyzing and reporting the final data. Ultimately, seventeen studies were deemed appropriate for examination within this scoping review and several key themes were identified. The results emphasize the importance of adopting a One Health approach, the key role that vaccination may well play in preventing the spread …

Rewriting The Rules: Impact Of Covid-19 On Norms In Science, The International Order, And China, Jacob Kissling '25

Honor Scholar Theses

The Covid-19 pandemic exposed both strengths and vulnerabilities in global responses, many of which were shaped by underlying norms and behavioral expectations within key institutions. Understanding how these norms influenced decision-making, collaboration, and communication—and how they were themselves challenged or reshaped by the crisis—can provide valuable insights for improving future responses. While some norms adapted in response to the evolving crisis, others remained stagnant or were inconsistently enforced, contributing to fragmented and, at times, ineffective responses. This paper investigates the role of norms in three critical sectors: the scientific community, the international order, and China. Within the scientific community, norms …

Racial And Ethnic Differences In Knowledge Of Gender-Affirming Care Among Community And Student Participants In The Bloom Transgender Health Education Program In The Paso Del Norte Region, 2022-2024, Tandra Ghosh

Open Access Theses & Dissertations

SUMMARY OF BACKGROUND AND SIGNIFICANCE: There is a noticeable lack of training and knowledge regarding gender-affirming care (GAC) among providers and within the general community. OBJECTIVE: Assess racial and ethnic disparities in knowledge of GAC among participants in BLOOM, a quasi-experimental transgender health education program in the Paso Del Norte region. HYPOTHESES: Among community and student participants at pre-survey, assess racial and ethnic differences in sociodemographic characteristics, preparedness, attitudes, and basic knowledge regarding LGBT clients/patients and GAC. METHODS: Secondary data among community (pre: 53; post: 14) and student (pre: 29; post: 17) BLOOM participants in 2022-2024 were used. Descriptive statistics …

Memory Matters: Cognitive Screenings For Dementia Detection In Monterey County, Cintia Gonzalez

Capstone Projects and Master's Theses

The rates of Alzheimer’s disease in Monterey County are increasing. The Healthy Aging program from the Monterey County Health Department strives to promote the well-being and health of older adults and caregivers in Monterey County by offering education on brain health, support in adopting healthy lifestyles, and connecting to community services. Memory Matters is an example of a training or educational intervention. The purpose of Memory Matters is to bridge the gap of insufficient access to early detection of dementia by bringing awareness to brain health, and facilitating the conversation of cognitive exams with older adults, their caregivers, and their …

Healthy Food, Healthy Future: Equitable Nutrition Access, Daisy Paredes

Capstone Projects and Master's Theses

While homelessness is a major global health issue, those without a place to live should have easy access to nutritional foods and medical care; otherwise, they risk developing long-term physical and mental health effects caused by circumstances beyond their control. The Community Action Board of Santa Cruz builds bridges to ensure everyone has access to resources and opportunities, regardless of race, ethnicity, gender, identity, immigration status, and other aspects of one’s identity. The capstone project enhances physical health by coordinating a weekly food distribution event for unhoused individuals in partnership with Second Harvest Food Bank. This allows us to reduce …