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Malignant Hyperthermia, Nicholas Colangelo
Malignant Hyperthermia, Nicholas Colangelo
Nursing Student Class Projects (Formerly MSN)
Malignant hyperthermia is a rare manifestation of a genetic mutation involving the ryanodine receptors. This mutation causes a sustained intracellular calcium release that is triggered by certain anesthetics such as depolarizing neuromuscular blockers and volatile gases. The extended release of calcium functions as a dangerous catalyst for hyper-metabolism that will lead to rapid death if unrecognized and untreated. Current treatment involves the drug dantrolene in tandem with symptomatic management in the intensive care setting. Symptomatic treatment may likely involve rapid cooling, fluid resuscitation, electrolyte management, and mechanical ventilation until symptoms resolve. A literature review of malignant hyperthermia is of vital …
Malignant Hyperthermia For The Nurse Anesthetist, Victor Clark
Malignant Hyperthermia For The Nurse Anesthetist, Victor Clark
Nursing Student Class Projects (Formerly MSN)
Malignant Hyperthermia (MH) is a rare, autosomal dominant skeletal muscle disorder that can have an insidious onset in susceptible patients exposed to the triggering agents succinylcholine, halothane, desflurane, sevoflurane, and isoflurane. MH can occur in patients who have received anesthesia with these agents in the past (Nagelhout & Plaus, 2018, p 775). Patients with a family history of MH or associated skeletal muscle disorder must be treated as MH-susceptible until proven otherwise. Failure to detect an MH crisis can lead to kidney failure, profound acidosis, coagulopathies, rhabdomyolysis, cardiac dysrhythmias, cardiovascular collapse, and death (Seifert et al., 2015). It is the …
Malignant Hyperthermia, Alec Smith
Malignant Hyperthermia, Alec Smith
Nursing Student Class Projects (Formerly MSN)
Abstract: There are many issues that healthcare professionals face in the evolving world of medicine. One of these is the development of a disease process known as Malignant Hyperthermia (MH). This condition is precipitated by frequently used anesthetic agents such as volatile gases and depolarizing muscle relaxants. The onset of MH is sudden and can be life-threatening, therefore, diligent monitoring of patients is essential in early recognition and treatment of MH. The purpose of this poster is to provide in -depth knowledge about MH. This includes the pathophysiology of the disease, signs and symptoms, treatment options, and implications MH has …