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Theses/Dissertations

Otterbein University

2021

Malignant Hyperthermia

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Full-Text Articles in Medicine and Health Sciences

Malignant Hyperthermia, Emmanuel Mensah Aug 2021

Malignant Hyperthermia, Emmanuel Mensah

Nursing Student Class Projects (Formerly MSN)

Malignant Hyperthermia is a rare but fatal disorder usually triggered using succinylcholine, a depolarizing muscle blocker, or other volatile anesthetics (Yang et al., 2020). MH is characterized by signs and symptoms including Hyperthermia, acidosis, tachycardia, hypercarbia, acidosis, etc. (Yang et al., 2020). When the signs and symptoms of MH are recognized, the provider should stop what he or she is doing and call for immediate help. When additional assistance arrives, the patient must receive Dantrolene. Dantrolene is a muscle relaxant that prevents the sarcoplasmic reticulum from releasing calcium. Additional interventions include cooling the patient using ice packs, treating electrolyte abnormalities, …


Malignant Hyperthermia, Courtney Morris Jan 2021

Malignant Hyperthermia, Courtney Morris

Nursing Student Class Projects (Formerly MSN)

Malignant Hyperthermia as defined by the International Classification of Diseases is a rare but progressive, and life-threatening hyperthermic reaction in response to a triggering agent such as general anesthetic gases or the depolarizing neuromuscular blocking agent Succinylcholine (Hopkins et. al., 2020). MalignantHyperthymia is a genetic disorder of the skeletal muscle, that leads to continuous muscle contraction and the inability to relax skeletal muscle (Haili and Weant, 2021). Signs and symptoms can vary from patient to patient and can be masked by anesthesia, but the classical signs include an increase in end-tidal CO2, increased heart rate, and a rapid increase in …