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Full-Text Articles in Medicine and Health Sciences

Movement Patterns During Functional Activities In People With Chronic Low Back Pain, Quenten Lowell Hooker Aug 2021

Movement Patterns During Functional Activities In People With Chronic Low Back Pain, Quenten Lowell Hooker

Arts & Sciences Electronic Theses and Dissertations

People with chronic LBP display an altered movement pattern where the lumbar spine moves more readily than other joints that can contribute to the activity. The pattern is of particular clinical relevance because across multiple studies the magnitude of altered pattern is associated with LBP and function. One session of motor skill training (MST) during functional activities can improve the altered pattern. However, of the few studies investigating MST for people with LBP, none have examined the short-term or long-term effects of MST on the altered pattern. Additionally, no study has systematically examined if person-specific characteristics moderate the altered pattern …


Hip And Pelvic Floor Strength And Mobility In Women With And Without Urgency And Frequency Predominant Lower Urinary Tract Symptoms, Stefanie N. Foster Jan 2021

Hip And Pelvic Floor Strength And Mobility In Women With And Without Urgency And Frequency Predominant Lower Urinary Tract Symptoms, Stefanie N. Foster

Arts & Sciences Electronic Theses and Dissertations

Urgency and frequency are common lower urinary tract symptoms (LUTS) in women and are accompanied by substantial activity and participation restrictions. Medical management begins with ruling out organ pathologies, typically followed by fluid intake and timed voiding often combined with pharmacologic management, and may progress to nerve stimulation, botulinum injections, or surgery where indicated. Despite abundant management options for urgency and frequency predominant LUTS (UF-LUTS) and high financial burden, patients often experience only partial relief from medical treatments for LUTS. While a great deal of literature exists to inform pharmacologic and surgical care of patients with UF-LUTS, less is known …


Midfoot And Ankle Movement Dysfunction In People With Diabetes Mellitus And Peripheral Neuropathy, Hyo Jung Jeong Jan 2021

Midfoot And Ankle Movement Dysfunction In People With Diabetes Mellitus And Peripheral Neuropathy, Hyo Jung Jeong

Arts & Sciences Electronic Theses and Dissertations

People with diabetes mellitus and peripheral neuropathy (DMPN) have midfoot and ankle musculoskeletal problems, including limited joint mobility and weakness and atrophy of foot intrinsic and calf muscles. Impaired foot structures and function could lead to midfoot and ankle movement dysfunction, measured by a heel rise task. A repeated movement dysfunction during weightbearing tasks (e.g., heel rise, walking) could cause excessive stress on the plantar tissue, which is a leading cause of plantar ulceration in people with DMPN. Understanding heel rise performance and the underlying mechanisms could help prevent the sequence of events associated with plantar ulcer development in people …


Rhythmic Auditory Cueing Of Gait In Parkinson Disease, Adam Patrick Horin May 2020

Rhythmic Auditory Cueing Of Gait In Parkinson Disease, Adam Patrick Horin

Arts & Sciences Electronic Theses and Dissertations

Parkinson disease (PD) is a neurodegenerative movement disorder characterized by motor complications such as gait deficits and is caused by the depletion of dopamine producing neurons in the basal ganglia (BG). Gait deficits, including decreased velocity and increased variability, are among the most debilitating symptoms of PD and lead to an increased risk of falls. Common pharmacological treatments do not target many gait symptoms. Therefore, gait rehabilitation methods that can improve these deficits in gait are highly important. A common form of gait rehabilitation is known as rhythmic auditory cueing, in which an individual matches their footfalls to the beat …


Structural And Tissue-Level Adaptations Of Lumbar Intervertebral Discs In Humans With Inducible Low Back Pain Symptoms, Christian Isaiah Weber Dec 2019

Structural And Tissue-Level Adaptations Of Lumbar Intervertebral Discs In Humans With Inducible Low Back Pain Symptoms, Christian Isaiah Weber

McKelvey School of Engineering Theses & Dissertations

Low back pain (LBP) is a devastating musculoskeletal ailment that impacts majority of the global population. Up to 95% of cases are considered nonspecific where the origin is unclear. Although there is a diagnosis with these cases, there lacks specificity that would help individuals with treatment and pain management. Imaging techniques such as magnetic resonance imaging (MRI) are primarily utilized in the diagnosis of LBP as it illuminates internal structures of the spine. One important structure clearly identified with MRI is the intervertebral disc (IVD) that is susceptible to injury and disease. Further, diagnostic imaging is performed lying down where …


Exploring The Complexities Of Real World Upper Limb Performance After Stroke, Kimberly Waddell May 2019

Exploring The Complexities Of Real World Upper Limb Performance After Stroke, Kimberly Waddell

Arts & Sciences Electronic Theses and Dissertations

Stroke is the leading cause of long-term disability in the United States. Hemiparesis, or weakness on one side of the body, is a common impairment following a stroke. Approximately 80% of individuals with stroke will experience upper limb paresis, with only a small percentage regaining full functional use of their paretic upper limb. Individuals report ongoing difficulties with incorporating their paretic upper limb into routine activities after a stroke. Rehabilitation interventions often try to increase real world upper limb use by improving what an individual is capable of doing (i.e. capacity) in the rehabilitation clinic. Both clinicians and researchers assume …


Freezing Of Gait: Mechanisms, Mechanics, And Management, Peter S. Myers Dec 2018

Freezing Of Gait: Mechanisms, Mechanics, And Management, Peter S. Myers

Arts & Sciences Electronic Theses and Dissertations

Parkinson disease (PD) is a neurodegenerative disease with multiple motor and non-motor symptoms, including postural instability, gait impairments, and cognitive deficits. More than 50% of individuals with PD experience a symptom called freezing of gait (FOG), described as a transient inability to take another step forward. Individuals with PD who experience FOG (freezers) have further postural, gait, and cognitive impairments compared to individuals with PD without FOG (non-freezers). While degeneration of the dopaminergic neurons in the substantia nigra is accepted as the primary etiology of the disease, research shows that the disease has a global impact on the brain, accounting …


Effects Of Resistance Exercise On Postprandial Metabolism In Obese Men With Prediabetes, Adam Bittel Aug 2018

Effects Of Resistance Exercise On Postprandial Metabolism In Obese Men With Prediabetes, Adam Bittel

Arts & Sciences Electronic Theses and Dissertations

Prediabetes is a metabolic condition defined by elevated fasting (impaired fasting glucose (IFG)) and/or postprandial (impaired glucose tolerance (IGT)) glucose. Prediabetes affects nearly 86 million adults in the United States, with most (up to 70%) progressing to type 2 diabetes within as little as one year. Recent studies have indicated that elevated post-prandial glycemia and hypertriglyceridemia are early indicators of prediabetes, and are major risk factors for complications of prediabetes, including cardiovascular disease (CVD), stroke, elevated blood pressure, and obesity. Resistance exercise is a central component of exercise recommendations for individuals with type 2 diabetes and prediabetes, but the effect …


Functional And Skeletal Muscle Impairments In Progressive Diabetic Ckd, Daniel Bittel Aug 2018

Functional And Skeletal Muscle Impairments In Progressive Diabetic Ckd, Daniel Bittel

Arts & Sciences Electronic Theses and Dissertations

1-in-3 persons with type 2 diabetes (T2DM) develop chronic kidney disease (CKD), which is characterized by progressive renal dysfunction leading to end-stage renal disease. In response to elevated blood glucose and systemic inflammation of diabetes, a process of active thickening of the renal glomerular basement membrane ensues with concomitant damage to the structural supports (podocytes) of the kidneyճ filtration barrier. This results in impaired renal filtration. The metabolic sequelea of T2DM and CKD also, synergistically, alter skeletal muscleճ degradative pathways, satellite cell function (muscle reparative cells), and mitochondrial health (muscle energetic machinery) -- resulting in muscle breakdown, poor muscle quality, …


Examining The Lumbar Movement Pattern During Functional Activities In People With Low Back Pain, Andrej Vincent Marich May 2017

Examining The Lumbar Movement Pattern During Functional Activities In People With Low Back Pain, Andrej Vincent Marich

Arts & Sciences Electronic Theses and Dissertations

Low back pain (LBP) is a highly prevalent condition that is often characterized by persistent pain and limitations in the performance of daily functional activities. The repeated use of altered movement patterns during the performance of daily functional activities is proposed to contribute to the development and course of LBP. Specifically, in the case of LBP, the proposed alteration of movement is one in which the lumbar spine moves more readily than other joints that can contribute to the movement. This altered movement pattern is proposed to contribute to accumulation of localized tissue stress, micro- and macro-trauma of lumbar spine …