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Articles 9121 - 9150 of 160281
Full-Text Articles in Medicine and Health Sciences
Disparities In Health Insurance And Delayed Care Among Hispanic Immigrants In The United States., Temitope Ayodele, Connor Fletcher, Kirk B Beredjiklian, Michael Valenzuela, Zane Mazur
Disparities In Health Insurance And Delayed Care Among Hispanic Immigrants In The United States., Temitope Ayodele, Connor Fletcher, Kirk B Beredjiklian, Michael Valenzuela, Zane Mazur
Orthopedic Surgery Resident Research
BACKGROUND: Hispanic immigrants in the United States face persistent barriers to healthcare, including lower rates of insurance coverage and a greater likelihood of delaying care due to cost. Clarifying the independent effects of ethnicity and nativity on these disparities is essential to inform effective policy.
METHODS: We analyzed pooled data from the 2019-2023 National Health Interview Survey (NHIS), accessed through the Integrated Public Use Microdata Series (IPUMS). Primary outcomes were being uninsured and delayed medical care due to cost in the past 12 months. Key independent variables were Hispanic ethnicity and nativity (US-born vs. foreign-born). Covariates included survey year, age, …
Bladder Prolapse (Cystocele) Among African, Asian, And Middle Eastern Women: A Clinical And Socio-Cultural Perspective.Intraoperative Frozen Section Analysis (Ifsa): One Plastic Surgeon’S Experience With 1598 Consecutive Skin Cancer Removals, Lawrence Chiang, Michael Chang, Steven Chang, Matthew Delancy, James Monihan, Ray Armand
Bladder Prolapse (Cystocele) Among African, Asian, And Middle Eastern Women: A Clinical And Socio-Cultural Perspective.Intraoperative Frozen Section Analysis (Ifsa): One Plastic Surgeon’S Experience With 1598 Consecutive Skin Cancer Removals, Lawrence Chiang, Michael Chang, Steven Chang, Matthew Delancy, James Monihan, Ray Armand
SKMC Student Presentations and Publications
BACKGROUND: Skin cancer continues to be the most frequently diagnosed cancer in the United States. Since 1990, the prevalence of melanoma and non-melanoma skin cancer (NMSC) has been steadily increasing.1 NCCN guidelines recommend complete excision of NMSC to preserve function and optimize aesthetic outcomes.2 The gold standard surgical treatment is Mohs Micrographic Surgery (MMS) with a reported cure rate of 99-100%.3 However, MMS requires specialized training and thus is more geographically and financially limited. The traditional technique utilized for skin cancer removal is intraoperative frozen section assessment (IFSA). IFSA is a common histopathological technique that facilitates microscopic …
Implementing A Pap Smear Tracking Tool For Increased Compliance, Meghan Marie Madea Msn, Cnm, Whnp-Bc, Katherine Ferrell Fouquier Phd, Cnm, Facnm, Bobby Bellflower Dnsc, Nnp-Bc, Faan, Faanp, Fnap
Implementing A Pap Smear Tracking Tool For Increased Compliance, Meghan Marie Madea Msn, Cnm, Whnp-Bc, Katherine Ferrell Fouquier Phd, Cnm, Facnm, Bobby Bellflower Dnsc, Nnp-Bc, Faan, Faanp, Fnap
Doctor of Nursing Practice Projects
Purpose/Background
The Papanicolaou “pap” smear screens for cervical cancer in women ages 21-65 with a cervix. Inconsistent locations for lab results lead to a decrease in provider efficiency, and patients are unaware of results or recommended follow-up. This quality improvement project implemented a tracking tool within the electronic medical record (EMR) in a busy midwifery clinic. The outcomes are the identification of patients overdue for pap smears, scheduling the procedure, recording of results, and patient notification with recommended follow-up.
Methods
A one-month chart review was performed of fifty gynecology patients within a midwifery clinic. Results of pap smears were located …
Herding Cats: Reflections On Designing And Implementing An Interprofessional Education Simulation, Valerie M. Wright, Antony Joseph
Herding Cats: Reflections On Designing And Implementing An Interprofessional Education Simulation, Valerie M. Wright, Antony Joseph
Faculty Publications - Mennonite College of Nursing
No abstract provided.
Lung Cancer In Patients Of African Descent: A Transcontinental Review Of Epidemiology, Disparities, Outcomes, And Opportunities For Equity In Africa, North America, South America, And The Caribbean, Elvis Obomanu, Colton Jones, Verna Vanderpuye, Nazik Hammad
Lung Cancer In Patients Of African Descent: A Transcontinental Review Of Epidemiology, Disparities, Outcomes, And Opportunities For Equity In Africa, North America, South America, And The Caribbean, Elvis Obomanu, Colton Jones, Verna Vanderpuye, Nazik Hammad
Division of Internal Medicine Faculty Papers & Presentations
Lung cancer in people of African descent is characterized by transcontinental disparities driven by epidemiologic heterogeneity, systemic inequities, and unequal access to health care. Globally, lung cancer incidence and mortality rates vary; however, underdiagnosis and late-stage presentation in low- and middle-income countries obscure the true prevalence of lung cancer because of limited cancer registries and diagnostic infrastructure. In Africa, most patients with lung cancer present at an advanced stage, primarily because of health illiteracy, misdiagnosis, delayed referrals, and inadequate treatment infrastructure. Although tobacco smoking remains a dominant risk factor worldwide, African populations are disproportionately exposed to environmental and occupational hazards, …
Hiv And Lung Cancer: A Single Cancer Center Experience, Julia Palecki, Matthew Tucker, Andrew Bernstein, Garrett Melby, Tingting Zhan, Ida Micaily
Hiv And Lung Cancer: A Single Cancer Center Experience, Julia Palecki, Matthew Tucker, Andrew Bernstein, Garrett Melby, Tingting Zhan, Ida Micaily
Division of Internal Medicine Faculty Papers & Presentations
Lung cancer (LC) is the leading cause of cancer death in people living with HIV (PLWH) and disproportionately affects this group regardless of CD4 count. At the Sidney Kimmel Comprehensive Cancer Center (SKCCC) at Jefferson Health, we treat an underserved PLWH population with LC and aim to study their clinical course, as they are often excluded from LC trials. We retrospectively reviewed 36 PLWH diagnosed with LC at Jefferson Health from 2016 to 2023. We found that 24 patients were male, 20 patients were Black, and that the median age of LC diagnosis is 66 years (range 38-83 years). 27 …
Dental Fluorosis As A Biomarker Of Environmental And Regulatory Failure In Tunisia’ S Gafsa Valley, Kenzy Aldaher
Dental Fluorosis As A Biomarker Of Environmental And Regulatory Failure In Tunisia’ S Gafsa Valley, Kenzy Aldaher
Tunisia and Italy: Politics and Religious Integration in the Mediterranean
No abstract provided.
Growth Measurements In Ugandan Children With Sickle Cell Anaemia From A Hydroxyurea (Hydroxycarbamide) Treatment Trial Relative To Unaffected Sibling Controls, Dennis Kalibbala, Vincent Mboizi, Grace Nambatya, Susan Murungi, Joan Ashaba, Catherine Nabaggala, Lynnth Turyagyenda, Deogratias Munube, Phillip Kasirye, Robert Opoka
Growth Measurements In Ugandan Children With Sickle Cell Anaemia From A Hydroxyurea (Hydroxycarbamide) Treatment Trial Relative To Unaffected Sibling Controls, Dennis Kalibbala, Vincent Mboizi, Grace Nambatya, Susan Murungi, Joan Ashaba, Catherine Nabaggala, Lynnth Turyagyenda, Deogratias Munube, Phillip Kasirye, Robert Opoka
Paediatrics and Child Health, East Africa
No abstract provided.
Salud Mental Intercultural En Un Entorno Urbano: Experiencias De Vista Mapuche Y Biomédico En La Pintana, Santiago, Jane Wu
Chile: Public Health, Traditional Medicine, and Community Empowerment
Historical migration from ancestral territories in La Araucanía has brought a large portion of the Mapuche population to Santiago, where La Pintana now hosts one of the city’s most concentrated Indigenous communities. These movements, shaped by discrimination, loss of language, and cultural displacement, have had lasting effects on mental health and identity for Mapuche residents living in an urban environment. This study asks how intercultural perspectives of healthcare influence the ways Mapuche and non-Mapuche populations navigate mental health in La Pintana. It analyzes the urban factors in La Pintana that influence mental health and the level of intercultural mental health …
A Word From The Writing Team (October 2025), Pam Walter, Mfa, Laura Deloretta, Phd
A Word From The Writing Team (October 2025), Pam Walter, Mfa, Laura Deloretta, Phd
A Word From the Writing Team (Newsletter)
This issue includes:
- Publications Spotlight
- Wiley is Hosting Two Workshops
- Join us for the Launch Party of Evanescent Issue 6: Growing. Learning. Aging.
- Pam is Out of the Office until October 14th!
- October 3rd is our First Friday Writing Retreat!
Cannabis Improves Metabolic Dysfunction And Macrophage Signatures In Obese Mice, Brandon N. Vanderveen, Thomas D. Cardaci, Christian A. Unger, Mitchell M. Nesmith, Jeffrey C. Freeman, Arianna V. Bastian, Kasie Roark, Mansi Upadhyay, Andrew G. Levy, Brooke M. Bullard, Sierra J. Mcdonald, Kandy T. Velázquez, Reilly T. Enos, Jason L. Kubinak, Lorne J. Hofseth Ph.D., James Hébert Scd, Daping Fan, E. Angela Murphy
Cannabis Improves Metabolic Dysfunction And Macrophage Signatures In Obese Mice, Brandon N. Vanderveen, Thomas D. Cardaci, Christian A. Unger, Mitchell M. Nesmith, Jeffrey C. Freeman, Arianna V. Bastian, Kasie Roark, Mansi Upadhyay, Andrew G. Levy, Brooke M. Bullard, Sierra J. Mcdonald, Kandy T. Velázquez, Reilly T. Enos, Jason L. Kubinak, Lorne J. Hofseth Ph.D., James Hébert Scd, Daping Fan, E. Angela Murphy
Faculty Publications
Obesity rates continue to rise, highlighting the need for new treatments that are effective, safe, and widely accessible. Aligned with the easing of restrictions on cannabis use, interest in its therapeutic potential is evolving. As such, we examined the effects of the cannabis plant with high cannabidiol (CBD) content or high Δ9-tetrahydrocannabinol (THC) content on metabolic and immune dysregulation in obese mice. Briefly, female C57BL/6 mice were randomized into four groups (n = 15/group): 1) lean, 2) obese placebo, 3) obese CBD, and 4) obese THC. Lean mice consumed a low-fat diet for the study …
Effect Of Sdf Application Versus Diode Laser Irradiation On Incipient Carious Lesion’S Progression In Primary Molars: A Randomize Clinical Trial, Islam Yehia, Noha Samir Kabil, Basma Gamal
Effect Of Sdf Application Versus Diode Laser Irradiation On Incipient Carious Lesion’S Progression In Primary Molars: A Randomize Clinical Trial, Islam Yehia, Noha Samir Kabil, Basma Gamal
Dentistry
The present study aimed to investigate the effect of two different preventive measures a) Silver diamine (SDF) application, b) Diode laser irradiation, on caries progression of incipient carious occlusal lesions in primary second molars. This clinical trial included two equal study groups of patients, for applying; Group I: SDF application, Group II: Diode laser irradiation, the included second primary molars for intervention were selected with incipient carious lesions graded by International Caries Detection & Assessment System (ICDAS)with scores (0,1,2). The involved molars were followed up for 3, 6, 12 months and ICDAS scores were graded to check for caries progression …
Effect Of Acid-Containing Drinks On Surface Roughness And Bacterial Accumulation Of Different Types Of Denture Base Materials, Sara Fikry Dr, Ayman Amin, Eman Khedr, Fatma Makkeya
Effect Of Acid-Containing Drinks On Surface Roughness And Bacterial Accumulation Of Different Types Of Denture Base Materials, Sara Fikry Dr, Ayman Amin, Eman Khedr, Fatma Makkeya
Dentistry
No abstract provided.
10-21-25 Bor Hsc Committee Agenda, Patricia Serna
10-21-25 Bor Hsc Committee Agenda, Patricia Serna
HSC Committee (A subcommittee of the UNM Board of Regents)
10-21-25 BOR HSC Committee Agenda
Use Of Modified Z-Domain Peptides To Specifically Label The Constant Region Of Immunoglobulin G And Vegf, Madeline Allen
Use Of Modified Z-Domain Peptides To Specifically Label The Constant Region Of Immunoglobulin G And Vegf, Madeline Allen
Department of Chemistry: Dissertations, Theses, and Student Research
Antibodies are increasingly being used in medicinal therapies due to their ability to specifically bind to a target antigen. This fundamental behavior of antibodies has been used as a key component in drug development to address common problems with traditional drug molecules such as off-targeting, fast drug clearance, and low efficacy. This thesis provides some background into how antibodies can be used as potential treatments for a few diseases. Chapter 1 begins with an overview of the human immune system, and the role antibodies play within it. Then, the variety of ways in which antibodies can be used as medicinal …
“Il N’Y A Plus De Monstres”: A Case Study On Trans And Gender-Diverse Health In Switzerland, Sophie Lin
“Il N’Y A Plus De Monstres”: A Case Study On Trans And Gender-Diverse Health In Switzerland, Sophie Lin
Switzerland: Global Health and Development Policy
Transgender and gender-diverse (TGD) populations experience significant health disparities, particularly in regards to mental health outcomes and quality of life. This case study employs a qualitative approach to elucidate barriers and enablers to TGD health and gender-affirming care in Switzerland. Evidence collected from semi-structured interviews with health professionals working with Swiss TGD communities provides a thorough understanding of contemporary resources and obstacles regarding gender-affirming treatment. This research seeks to contribute to scholarship by synthesizing health literature with critical queer theory. Drawing from Butler’s theory of gender performativity, a framework of gender self-determination is advanced as a core principle of health, …
From Measures To Meaning: A Case Study On Co-Defining Aphasia Recovery Outcomes With Patient Experts, Ann Blair Kennedy, Amy Neira, Katie Parris, Sebrena Brink, Patients With Aphasia Panel, Nabil Natafgi, Dirk B. Den Ouden, Sara Sayers, Leonardo Bonilha, Julius Fridriksson
From Measures To Meaning: A Case Study On Co-Defining Aphasia Recovery Outcomes With Patient Experts, Ann Blair Kennedy, Amy Neira, Katie Parris, Sebrena Brink, Patients With Aphasia Panel, Nabil Natafgi, Dirk B. Den Ouden, Sara Sayers, Leonardo Bonilha, Julius Fridriksson
Communication Sciences and Disorders Faculty Articles and Research
Background
People with post-stroke aphasia are often excluded from shaping the research meant to support their recovery. Communication barriers, research norms, and traditional outcome frameworks contribute to a lack of meaningful involvement, particularly in the identification of patient-centered outcomes. While participatory models in aphasia research are emerging, few examples describe how individuals with communication disabilities can lead or co-create research priorities.
Main body
This case study describes a structured, collaborative effort to center the voices of people with aphasia in identifying meaningful outcomes for recovery. Through a partnership between the Patient Engagement Studio (PES) and the Center for the Study …
Integrating Mobility Dynamics Into Facility Location Modeling And Optimization, Daniel Hopkins
Integrating Mobility Dynamics Into Facility Location Modeling And Optimization, Daniel Hopkins
College of Engineering Summer Undergraduate Research Program
Facility location optimization is a foundational area in operations research and data analytics that is concerned with determining the optimal placement of facilities to serve a spatially distributed demand. However, traditional facility location decision is often approached from a centralized perspective, where the facility planner dictates the allocation of customers to facilities. In this setting, it is typically assumed that customers patronize the nearest facility, and their preferences are not explicitly modeled. This traditional decision-making framework may not accurately reflect real-world dynamics where customers may choose facilities based on a variety of factors beyond proximity. Thus, this project aims to …
Changes In Antiviral Prescribing For Children With Influenza In Us Emergency Departments., Tess Stopczynski, Olla Hamdan, Justin Z. Amarin, James W. Antoon, Laura S. Stewart, Haya Hayek, James Chappell, Andrew J. Spieker, Eileen J. Klein, Janet A. Englund, Geoffrey A. Weinberg, Peter G. Szilagyi, John V. Williams, Marian G. Michaels, Julie A. Boom, Leila C. Sahni, Mary Allen Staat, Elizabeth P. Schlaudecker, Jennifer E. Schuster, Rangaraj Selvarangan, Ayzsa Tannis, Heidi L. Moline, Samantha M. Olson, Natasha B. Halasa
Changes In Antiviral Prescribing For Children With Influenza In Us Emergency Departments., Tess Stopczynski, Olla Hamdan, Justin Z. Amarin, James W. Antoon, Laura S. Stewart, Haya Hayek, James Chappell, Andrew J. Spieker, Eileen J. Klein, Janet A. Englund, Geoffrey A. Weinberg, Peter G. Szilagyi, John V. Williams, Marian G. Michaels, Julie A. Boom, Leila C. Sahni, Mary Allen Staat, Elizabeth P. Schlaudecker, Jennifer E. Schuster, Rangaraj Selvarangan, Ayzsa Tannis, Heidi L. Moline, Samantha M. Olson, Natasha B. Halasa
Manuscripts, Articles, Book Chapters and Other Papers
IMPORTANCE: Despite national recommendations, antiviral prescribing in emergency departments (EDs) for children at higher risk of severe influenza, such as those younger than 5 years and those with specific underlying conditions, remains low.
OBJECTIVE: To assess whether there were changes in antiviral prescribing for children at higher risk of severe influenza in academic pediatric EDs before the COVID-19 pandemic (2016-2020) vs the late pandemic period (2021-2023).
DESIGN, SETTING, AND PARTICIPANTS: This multicenter, cross-sectional study included influenza-positive children younger than 18 years presenting to the ED at 1 of 7 US pediatric academic hospitals participating in the Centers for Disease Control …
Assessment And Management Of Magnesium And Trace Element Status In Children With Ckd Stages 2-5, On Dialysis And Post-Transplantation: Clinical Practice Points From The Pediatric Renal Nutrition Taskforce., Jetta Tuokkola, Caroline E. Anderson, Sheridan Collins, Pearl Pugh, Molly R Wong Vega, Matthew Harmer, Lyndsay A. Harshman, Christina L. Nelms, Barry Toole, An Desloovere, Fabio Paglialonga, Nonnie Polderman, José Renken-Terhaerdt, Rukshana Shroff, Evelien Snauwaert, Stella Stabouli, Johan Vande Walle, Bradley A. Warady, Vanessa Shaw, Larry A. Greenbaum
Assessment And Management Of Magnesium And Trace Element Status In Children With Ckd Stages 2-5, On Dialysis And Post-Transplantation: Clinical Practice Points From The Pediatric Renal Nutrition Taskforce., Jetta Tuokkola, Caroline E. Anderson, Sheridan Collins, Pearl Pugh, Molly R Wong Vega, Matthew Harmer, Lyndsay A. Harshman, Christina L. Nelms, Barry Toole, An Desloovere, Fabio Paglialonga, Nonnie Polderman, José Renken-Terhaerdt, Rukshana Shroff, Evelien Snauwaert, Stella Stabouli, Johan Vande Walle, Bradley A. Warady, Vanessa Shaw, Larry A. Greenbaum
Manuscripts, Articles, Book Chapters and Other Papers
Children and young people with chronic kidney disease (CKD) are at risk for deficiency or excess of magnesium and trace elements. Kidney function, dialysis, medication, and dietary and supplemental intake can affect their biochemical status. There is much uncertainty about the requirements of magnesium and trace elements in CKD, which leads to variation in practice. The Pediatric Renal Nutrition Taskforce is an international team of pediatric kidney dietitians and pediatric nephrologists, formed to develop evidence-based clinical practice points to improve the nutritional care of children with CKD. PICO (patient, intervention, comparator, and outcomes) questions led the literature searches, which were …
The Impact Of Long-Term Exposure To Lip Cosmetics On The Fertility Of Female Drosophila Melanogaster, Neeka Oghli
The Impact Of Long-Term Exposure To Lip Cosmetics On The Fertility Of Female Drosophila Melanogaster, Neeka Oghli
Holster Scholar Projects
Are products marketed as safe to use, truly safe to use? Inspired by an article exposing the dangers of Tampax tampons, this study examines potential reproductive risks from consumer lip products marketed as natural and safe18. Drosophila melanogaster, a model organism with genetic and reproductive similarities to humans, was utilized to test the impacts of Rhode and Avène lip cosmetics. Avène’s Cicalfate + Lips Repair Lip Balm is the closest alternative to Rhode’s unscented peptide lip treatment, which was mindfully chosen to test if affordability comes at the expense of safety. Various concentrations of these products will be exposed to …
Scalable Long-Read Nanopore Hpv16 Amplicon-Based Whole-Genome Sequencing, Maina Titus, David Giesbrecht, Cliff Oduor, Kapten Muthoka, Karamoko Niaré, Rebecca Crudale, Abebe Fola, Sin Hui, Isaac Kim Jr., Elkanah Orang'o
Scalable Long-Read Nanopore Hpv16 Amplicon-Based Whole-Genome Sequencing, Maina Titus, David Giesbrecht, Cliff Oduor, Kapten Muthoka, Karamoko Niaré, Rebecca Crudale, Abebe Fola, Sin Hui, Isaac Kim Jr., Elkanah Orang'o
Obstetrics and Gynaecology, East Africa
Human papillomavirus 16 (HPV16) drives precursor cervical lesions that often progress to cervical cancer (CC). Variation within the HPV16 genome has been associated with CC risk. Here, we developed an affordable and portable amplicon-based long-read whole genome sequencing (WGS) approach using Oxford Nanopore Technologies to investigate HPV16 genetic diversity among women in sub-Saharan African countries. Applied to a control CaSki cell line and clinical samples (n = 12), our method generated complete HPV16 genomes at high coverage (median read coverage: 5,899–15,279 ×). Benchmarking our HPV16 controls showed high accuracy for two variant calling pipelines (Clair3 and PEPPER-Margin DeepVariant). Phylogenetic analysis …
Emergency Medicine Pharmacist Prescriptive Authority For Resolution Of Outpatient Prescription Issues, Kevin Burnham, Christina Tran, Leandra Garcia, Julian Mccreary, Christo Philip, Osama A. Shoair
Emergency Medicine Pharmacist Prescriptive Authority For Resolution Of Outpatient Prescription Issues, Kevin Burnham, Christina Tran, Leandra Garcia, Julian Mccreary, Christo Philip, Osama A. Shoair
Pharmacy Faculty Publications and Presentations
Objectives: To describe the implementation and impact of a collaborative practice agreement (CPA) for emergency medicine pharmacists (EMPs) that grants them broad prescriptive authority to resolve outpatient discharge prescription issues independently. Methods: We conducted a retrospective chart review of all prescriptions written by EMPs under a CPA to resolve discharge prescription issues at a 70-bed emergency department (ED) within a large health system in South Dallas, Texas. This review covered the period from November 1, 2021, to June 30, 2023. EMPs were authorized to independently address prescription problems without a provider’s direct involvement. We collected data on patient demographics, the …
Health-Related Quality Of Life In Covid-19 Patients: A Systematic Review And Meta-Analysis Of Eq-5d Studies, Kidu Gidey, Yirga Legesse Niriayo, Solomon Weldegebreal Asgedom, Erica I. Lubetkin
Health-Related Quality Of Life In Covid-19 Patients: A Systematic Review And Meta-Analysis Of Eq-5d Studies, Kidu Gidey, Yirga Legesse Niriayo, Solomon Weldegebreal Asgedom, Erica I. Lubetkin
Publications and Research
Background
COVID-19 has affected millions globally, with a significant proportion experiencing long-COVID and impaired health-related quality of life (HRQoL). This systematic review and meta-analysis aimed to synthesize the existing literature on HRQoL in COVID-19 patients.
Methods
We conducted a systematic search of PubMed, Embase, Web of Science, Scopus, and the Cochrane Library for studies published between December 2019 and March 2025. Eligible studies were peer-reviewed and assessed HRQoL in COVID-19 patients using the EQ-5D instrument. Study quality and risk of bias were evaluated using the Newcastle-Ottawa Scale. Pooled health utility values were estimated using a random-effects model, and heterogeneity was …
Culturally Tailored Guide For South Asian Dementia Caregivers, Lydia Skaria
Culturally Tailored Guide For South Asian Dementia Caregivers, Lydia Skaria
Occupational Therapy Student Scholarship
Capstone poster presentation from the The Minute Thesis Competition on Binghamton University Campus.
Global Transfusion Practices In Septic Patients In The Intensive Care Unit: Insights From The Input-Study Sub-Analysis, Vincent Kurucz, Andrew Flint, Alexis Poole, Merijn Reuland, Claudia Oord, Caroline Schaap, Jan Bakker, Maurizio Cecconi, Aarne Feldheiser, Marcus Lance
Global Transfusion Practices In Septic Patients In The Intensive Care Unit: Insights From The Input-Study Sub-Analysis, Vincent Kurucz, Andrew Flint, Alexis Poole, Merijn Reuland, Claudia Oord, Caroline Schaap, Jan Bakker, Maurizio Cecconi, Aarne Feldheiser, Marcus Lance
Anaesthesiology, East Africa
Background Transfusion practices among intensive care unit (ICU) patients with sepsis vary widely. While restrictive hemoglobin thresholds for red blood cell (RBC) transfusion are well studied, the indications and thresholds for platelet and plasma transfusions remain uncertain.
Methods We performed a sepsis-specific sub-analysis of the International Point Prevalence Study of Intensive Care Unit Transfusion Practices, a prospective, multicenter, observational study capturing all adult ICU admissions during four pre-scheduled weeks between March 2019 and October 2022. Patients admitted with sepsis or septic shock, or who developed sepsis during their ICU stay, were included. We recorded demographics, daily laboratory values, and transfusion …
Law Library Blog (October 2025): Legal Beagle's Blog Archive, Roger Williams University School Of Law
Law Library Blog (October 2025): Legal Beagle's Blog Archive, Roger Williams University School Of Law
Law Library Newsletters/Blog
No abstract provided.
Improving Health Behaviors And Symptoms In Youth With Mental Health Disorders: The Gamerfit Rct, April Bowling, Alyssa M. Button, Robbie Beyl, James Slavet, Tara Daly, Peyton Murray, Phillip Nauta, Amanda Staiano
Improving Health Behaviors And Symptoms In Youth With Mental Health Disorders: The Gamerfit Rct, April Bowling, Alyssa M. Button, Robbie Beyl, James Slavet, Tara Daly, Peyton Murray, Phillip Nauta, Amanda Staiano
Health Sciences Faculty Publications
Objective
We tested GamerFit, a theory-based health coaching and exergaming intervention delivered via mHealth app for feasibility and preliminary efficacy to improve physical activity (PA), sleep, perceptions of barriers and support, and mental health outcomes in youth with heterogeneous/comorbid mental health disorders (HCMHD).Methods
A convenience sample of youth ages 13–17 with HCMHD were recruited via clinical referral, listservs, and media platforms. The primary outcome of feasibility was assessed relative to the original intervention, which was not delivered via mHealth app. Groupings were randomized 1:1 to the 12-wk GamerFit intervention arm (GamerFit) or active comparator arm (AC) using single-blind design …Fascia Iliaca Compartment Block And Pericapsular Nerve Group Block Effect On Opioid Consumption In Hip Fracture Patients, David A. Brueggeman, Garrhett G. Via, Prachi Lele, Andrew W. Froehle, Michael J. Prayson, Scott J. Hadaway
Fascia Iliaca Compartment Block And Pericapsular Nerve Group Block Effect On Opioid Consumption In Hip Fracture Patients, David A. Brueggeman, Garrhett G. Via, Prachi Lele, Andrew W. Froehle, Michael J. Prayson, Scott J. Hadaway
Orthopaedic Surgery Faculty Publications
Background Effective pain control and reduced opioid consumption improve hip fracture outcomes. Fascia iliaca compartment blocks (FICB) effectively and safely manage acute hip fracture pain while reducing opioid consumption. Alternatively, pericapsular nerve group (PENG) blocks may provide similar analgesia while better-preserving motor function by targeting the highly innervated anterior hip capsule and sensory branches of the femoral, obturator, and accessory obturator nerves. Evidence for PENG's effectiveness is limited. The present retrospective study compared pain and MME in hip fracture patients receiving FICB (n = 1596) or PENG (n = 254), vs. a no-block (NB; n = 287) reference group. Methods …
Concurrent Local Therapy Extends Clinical Benefit Of Tebentafusp In Metastatic Uveal Melanoma Patients, Tristan L. Lim, Kamaneh Montazeri, Eric Wehrenberg-Klee, Antoine Desilets, Rino S. Seedor, Marlana Orloff, Takami Sato, Michael Caplan, Mariam El-Ashmawy, Benjamin Izar, Shaheer Khan, Inderjit Mehmi, Aleigha Lawless, Theodore S. Hong, Omid Hamid, Richard D. Carvajal, Alexander Shoushtari, Ryan J. Sullivan
Concurrent Local Therapy Extends Clinical Benefit Of Tebentafusp In Metastatic Uveal Melanoma Patients, Tristan L. Lim, Kamaneh Montazeri, Eric Wehrenberg-Klee, Antoine Desilets, Rino S. Seedor, Marlana Orloff, Takami Sato, Michael Caplan, Mariam El-Ashmawy, Benjamin Izar, Shaheer Khan, Inderjit Mehmi, Aleigha Lawless, Theodore S. Hong, Omid Hamid, Richard D. Carvajal, Alexander Shoushtari, Ryan J. Sullivan
Kimmel Cancer Center Faculty Papers
BACKGROUND: Tebentafusp has significantly improved overall survival in HLA-A*02:01+ metastatic uveal melanoma (mUM) patients even in those with a best objective response of progressive disease. Thus, strategies to maintain tebentafusp therapy are critical. Here, we examine the efficacy and safety of adding concurrent local therapy (CLT) to tebentafusp upon radiological progression with tebentafusp alone.
PATIENTS AND METHODS: This multicenter retrospective study included mUM patients treated with tebentafusp and CLT, consisting of extrahepatic soft tissue irradiation and liver-directed therapies (LDTs). Efficacy of target and nontarget sites were assessed per RECIST version 1.1. PFS with tebentafusp alone (PFS1) was compared to that …