Medicine and Health Sciences Commons^™

Aac In Schools: How District Infrastructure And At Specialists Shape Implementation Practices, Grace T. Clark, Lesley Rytel, Endever* Corbin, Madison Skibicki, Gabriella Pesantes

Department of Communication Sciences and Disorders Faculty Scholarship and Creative Works

Purpose

Research on barriers to augmentative and alternative communication (AAC) implementation in schools has focused primarily on individual clinician factors rather than district infrastructure. This clinical focus article examined how the presence or absence of a dedicated assistive technology (AT) specialist was associated with differences in AAC implementation and the use of AAC as a Tier 1 support.

Method

Eighteen educators, including AT specialists, SLPs, and a special educator, from 17 U.S. school districts participated in a 75-minute structured Zoom focus group. They rated 11 statements about district AAC practices using a 4-point Likert scale and discussed their responses in …

Importance Of Placental Evaluation In Pregnancies At High Risk For Placenta Accreta Spectrum: Expert Clinical Perspective, Rebecca H. Jessel, Alesha White, Hope Y. Yu, Amie L. Hollard, Meena Khandelwal, Carolyn M. Zelop, Jennifer Philips, Alireza A. Shamshirsaz, John C. Kingdom, Alfred Abuhamad, Christina L. Herrera, Pan American Society For Placenta Accreta Spectrum (Pas2)

Department of Obstetrics & Gynecology Faculty Publications

Background

Placenta accreta spectrum (PAS) is a leading cause of obstetric morbidity and peripartum hysterectomy. Rising cesarean delivery rates, advanced maternal age, and assisted reproductive technologies have increased its incidence. Early, standardized diagnosis is essential for multidisciplinary planning and improved outcomes, yet formal screening guidelines are lacking.

Objective

To raise awareness of the importance of antenatal screening for PAS, summarize key clinical and imaging risk factors, and propose a standardized mid-trimester ultrasound protocol for high-risk patients.

Methods

An expert panel convened under the Pan-American Society for the Placenta Accreta Spectrum (PAS2) reviewed available evidence, risk stratification models, and prior consensus …

Nativity And English Language Use In Relation To Undiagnosed And Diagnosed Diabetes In U.S. Adults, Aliya Kuerban Phd, Fnp-Bc, Ms, Ma, Rn

Nursing: Faculty Presentations

Introduction and Objective: Diabetes detection varies across demographic and immigration-related groups. Foreign-born adults and individuals with limited English proficiency may be less likely to have diabetes identified, even when the disease is present. This study examined demographic, socioeconomic, and immigration-related correlates of undiagnosed and diagnosed diabetes among U.S. adults.

Methods: Data from the National Health and Nutrition Examination Survey (NHANES, 2011-2023) were analyzed using survey-weighted multinomial logistic regression. Diabetes status was categorized as no diabetes, undiagnosed diabetes, or diagnosed diabetes based on self-report and laboratory criteria. Models sequentially adjusted for age, sex, race/ethnicity, nativity, English language use, income, and education. …

Identification Of Culturable Moulds, Audrey Bernèche-D'Amours, Thi Thanh Tam Nguyen, Delphine Lanoie

Microbiologiques

Cette méthode est utilisée pour identifier au genre ou à l’espèce des moisissures cultivées à partir d’échantillons d’air, de surface ou de matrices solides ou liquides. Après avoir isolé une souche de moisissure en culture pure, différentes techniques peuvent être utilisées : l’observation des caractères macroscopiques et microscopiques des colonies et leur comparaison à des clés d’identification de référence, la spectrométrie de masse utilisant la technologie MALDI-TOF et le séquençage de type Sanger ciblant différents loci génétiques. Les identifications obtenues par l’une, plusieurs ou l’ensemble de ces techniques sont ensuite interprétées pour rapporter une identification finale.

Abstract

This method is …

A Novel Tyrosine Kinase Axis In Innate Immune Signaling, Santanu Das, Pracheta Sengupta, Manoj Veleeparambil, Saurabh Chattopadhyay

Microbiology, Immunology, and Molecular Genetics Faculty Publications

Tyrosine phosphorylation has emerged as a central regulatory mechanism in innate immunity. Building on our recent studies that Syk and EGFR sequentially phosphorylate TLR9 to fully activate it, we discuss how similar mechanisms operate across other Toll-like receptors and the cytosolic DNA sensor STING. Evidence from complementary systems reveals that receptor and nonreceptor tyrosine kinases, including Src-family kinases, Syk, BTK, and EGFR, form an integrated signaling network that triggers receptor activation, trafficking, and downstream gene expression. Scavenger receptors such as SR-A further drive this kinase cascade by coordinating viral recognition to TLR activation. These observations reveal a novel ‘tyrosine kinase …

Maternal Opioid Use Disorder And Hepatitis C Infection In Pregnancy Reshape The Peripheral Immune Landscape At Term, Brianna M. Doratt, Heather E. True, Sheridan B. Wagner, Delphine C. Malherbe, Zachary M. Reynolds, Cynthia Cockerham, John O'Brien, Ilhem Messaoudi

Microbiology, Immunology, and Molecular Genetics Faculty Publications

Background: Pregnancy requires precisely timed immune adaptations to maintain foetal tolerance while enabling timely initiation of labour, a process often conceptualised as the ‘immune clock’ of pregnancy. Disruption of this immune clock contributes to adverse obstetric outcomes. While maternal opioid use disorder (OUD) is a recognised risk factor for poor maternal and neonatal health, its impact on maternal immune landscape at delivery remains poorly understood.

Methods: We analysed peripheral blood collected from pregnant individuals with and without OUD at time of admission for delivery before the onset of active labour. We employed multiparameter flow cytometry, cytokine profiling, and single-cell-RNA sequencing …

An Environmentally Relevant Phthalate Mixture Impairs Ovulatory Prostaglandin And Progesterone Receptor Pathways In Human Granulosa Cells In Vitro, Katie L. Land, Hong Xu, James W. Akin, Patrick R. Hannon

Obstetrics and Gynecology Faculty Publications

Ovulatory defects are the leading cause of female infertility. Widespread exposure to endocrine-disrupting chemicals, such as phthalates, may contribute to the high prevalence of failed ovulation among infertile women. Using primary ovarian granulosa cells obtained from women, we tested the hypothesis that exposure to an environmentally relevant mixture of phthalate metabolites (MPTmix) impairs essential mediators of the ovulatory process, including progesterone (P4), progesterone receptor (PGR), and prostaglandins (PGs). The composition of the MPTmix was derived from urinary phthalate levels in women. Ovarian granulosa cells, obtained from in vitro fertilization patients, were acclimated in culture to regain responsiveness to hCG (human …

Animal Models Of Aortic Aneurysm And Dissection: A Comparative Guide For Mechanism, Therapeutic Testing, And Translational Readouts, Shayan Mohammadmoradi, Sidney W. Whiteheart

Saha Cardiovascular Research Center Faculty Publications

Aortic aneurysms and dissections are devastating vascular diseases with high mortality, yet no pharmacological therapy has proven effective in halting growth or preventing rupture. Surgical and endovascular repair remain the only treatment options for advanced disease. Animal models have been indispensable in defining mechanisms and testing candidate therapies, but the diversity of protocols, strain-dependent variability, and heterogeneous endpoints complicate interpretation and translation. This review provides an update focused on how to match models to specific research questions. We critically compare commonly used abdominal aortic aneurysm (AAA) models (angiotensin II ± hyperlipidemia, elastase, calcium chloride, β-aminopropionitrile BAPN hybrids, and mineralocorticoid agonist/fludrocortisone …

Affordability And Serving Accuracy Of A Publicly Available Dash Meal Plan For Women Using Snap Benefits, Kendra Oonorasak, Mansura Shahad Bawa, Nadia Ayesha Sesay, Emma Smith, Taylor Emerson, Jayden Brewer, Brandi M. White

Health and Clinical Sciences Faculty Publications

Background/Objectives: This regional case study evaluated the affordability and serving accuracy of a publicly available one-week DASH meal plan for single-woman households using Supplemental Nutrition Assistance Program (SNAP) benefits in central Kentucky.

Methods: For each food item in the one-week plan, total grocery costs and per-serving costs were calculated using January 2025 prices from two national grocery chains commonly patronized in an urban area in central Kentucky. Calculated costs were compared to the average weekly food cost for women aged 20–50 years in a single household based on the Thrifty Food Plan (TFP). Servings for food groups and categories were …

Feasibility Study Of A Screening Decision Tool For Allocating Adults Into Food Is Medicine Programs As An Effective Approach To Target Clinical And Dietary Outcomes Among Rural And Urban Adults, Alison Gustafson, Carolyn Lauckner, Joshua L. Bush, Emily Dimond, Carolina Morales Serrano, Christa Mayfield, Elizabeth T. Anderson Steeves

Dietetics and Human Nutrition Faculty Publications

Objective: Evaluate feasibility (primary), clinical, and cost outcomes (secondary) associated with the use of a screening decision tool for allocating rural and urban adults with hypertension into in a food is medicine (FIM) program.

Design: Participants were allocated to receive either medically tailored meals or grocery prescription (Rx), based on a user-centered designed screening decision tool. Medically tailored meals (MTM) provided 5 meals per week for 12 weeks. The grocery Rx program provided $100 each month for 3 months to purchase food consistent with guidelines for hypertension. Feasibility outcomes included engagement, dose, and program acceptability. Semi-structured interviews were completed with …

Psycinfo Platforms: A Tale Of Two Interfaces (Ovid Vs Ebsco), Sandra Yvette Desjardins, Jamie Quinn

Library Staff Publications

PsycInfo is a foundational database for evidence-based behavioral health literature, which makes it an essential tool for health sciences librarians. This column provides a comprehensive comparison of PsycInfo on Ovid and EBSCO platforms. It offers a foundational overview for new librarians, guiding them through essential functionalities and navigation. The article also helps librarians evaluate potential database acquisitions by highlighting the distinct features and search capabilities of each interface. This comparison aims to equip health sciences librarians with the knowledge to optimize search strategies and inform strategic purchasing decisions.

Behavioral And Psychological Financial Hardship Among Caregivers Of Pediatric Cancer Patients, Josiane Kabayundo, Cheng Zheng, Edward S. Peters, Don W. Coulter, Shinobu Watanabe-Galloway

Journal Articles: Epidemiology

BACKGROUND: Financial hardship encompasses material, behavioral, and psychological domains; however, most research among caregivers of pediatric cancer patients has focused on material hardship. This study examined factors associated with behavioral and psychological financial hardship among caregivers of pediatric cancer patients in Nebraska.

METHODS: We conducted a cross-sectional survey of caregivers of children diagnosed within the past 5 years and treated at two pediatric oncology specialty clinics. Behavioral hardship was defined as delaying medical or mental healthcare due to cost, while psychological hardship was measured by worry about ability to pay medical bills. Descriptive statistics and poisson regression with robust variance …

Predicting Off-Track Development In Infants Aged 0–6 Months In Low-Resource Settings Using Machine Learning, Faith Benson, Rachel Odhiambo, Anthony Ngugi, Willie Brink, Akbar Waljee, Cheryl Moyer, Ji Zhu, Felix Agoi, Amina Abubakar

Institute for Human Development, East Africa

Background This study aimed to address the critical gap in the limited application of machine learning (ML) for identifying developmental delays in low-resource settings by developing models to predict off-track development in infants aged 0 to 6 months and identify key predictors.

Methods A cross-sectional study involving 1,995 singleton infants aged 0 to 6 months was conducted in Kaloleni and Rabai sub-counties, Kilifi, Kenya, between March 2023 and March 2024. Development was assessed using the World Health Organization’s Indicators of Infant and Young Child Development tool, with Development-for-Age Z-scores used to classify infants as on- or off-track. Ridge logistic regression …

Procedural-Based Contemporary Management Of Bell's Palsy Long-Term Sequelae: A Narrative Review, Robert M. Frederick, Rhorie Kerr, Eric Dobratz, William Dougherty

Department of Otolaryngology (ENT) Faculty Publications

Objective

To describe the long-term sequelae of Bell's palsy and summarize available treatment options, including recent advances, so that general otolaryngologists and other practitioners are aware of the clinical findings and available interventions.

Data Sources

PubMed.

Review Methods

A literature search was performed on December 18, 2024, via PubMed using keywords such as "synkinesis," "selective myectomy," "selective neurectomy," "botulinum toxin," "intervention" in the context of "Bell's palsy" with preference for articles published within the last 5 to 10 years but inclusion of select older articles that provided necessary context for the current topic. Articles included in the review were written …

Differences In Biologic Clinical Trials For Chronic Rhinosinusitis With Nasal Polyps—Are We Comparing Apples With Oranges?, Marjolein Cornet, Peter W. Hellings, Martin Desrosiers, Martin Wagenmann, Richard Follows, Laura Walrave, Luz Adriana Jimenez, Lee Tombs, Dawn Edwards, Peter Howarth, Joseph K. Han

Department of Otolaryngology (ENT) Faculty Publications

In recent years, several biologics targeting Type 2 inflammation have been developed for treating chronic rhinosinusitis with nasal polyps (CRSwNP). These have been studied in registrational randomized controlled trials (RCTs), which vary in their patient populations, trial design, endpoints, geography, timing, or data-handling processes. While (in)direct treatment comparisons and meta-analyses have been carried out to compare efficacy results from RCTs, often these fail to properly account for these between-study differences. Here, we summarize the key between-study differences that can influence trial outcomes and highlight the resulting challenges faced when comparing outcomes from different Phase III RCTs of biologics in CRSwNP.

Storytelling & Simulation-Based Experiences (Sbes): Immersive Environments That Support Student Learning, Meredith Deegan, Lauren Goeke, Kristina Sandberg, Josh Blubaugh, Kimberly Davis, Mary Murigi

School of Nursing Publications

Storytelling and Simulation-Based Experiences (SBEs) offer a powerful, equity-minded approach to teaching population health. Drawing on the NLN Jeffries Simulation Theory, Kolb’s experiential learning model, and the AACN 2021 Essentials, this session presents a SBE that integrates narrative design to immerse learners in community-centered care through a simulated Federally Qualified Health Center (FQHC) waiting room experience.

This SBE places students in a crowded FQHC waiting room to explore cultural humility, empathy, and health promotion in underserved settings. After the prebrief establishing purpose and psychological safety, students enter a conference room transformed with tight seating, limited walking space, and ambient noise. …

A Systematic Review Of Disparities In Alzheimer’S Diagnosis: The Overlooked Impact Of Gender And Ethnoracial Diversity On Biomarker Expression, Cynthia Smith, Olisaemeka Ogbue, Nasra Gathoni, Karen Blackmon, Tamlyn J. Watermeyer, Jasmit Shah, Chinedu Momoh

Brain and Mind Institute

Background: Biomarkers hold significant promise for the early diagnosis of dementias like Alzheimer's disease (AD). However, less than 5% of research data originates from Black African or African American populations, despite Africa's increasing dementia burden. Additionally, women are disproportionately affected by dementia globally, a trend that is expected to persist. This systematic review aims to synthesize studies on sex and gender differences in AD biomarkers, with a focus on African populations.

Method: We have conducted systematic searches across PubMed, Scopus, Web of Science, SciELO, and African journals online for articles published between 2000 and 2024. Our focus is …

Comparison Of Spayed Heifer Performance To Intact Heifers Fed Melengestrol Acetate On Feedlot Performance And Carcass Characteristics, Tate S. Johnson, Rebecca L. Mcdermott, Halden J. Clark, Jim C. Macdonald, Jessica L. Sperber

Nebraska Beef Cattle Reports

Summary with Implications

Pregnancy and estrous cycle management are critical considerations when feeding intact heifers in the feedyard. Alternatively, producers can opt to spay heifers, which eliminates hormonal fluctuations associated with the estrous cycle. A proportion of U.S. feedlots have spayed heifers on feed, although there is limited data comparing the performance of spayed heifers to intact heifers. A commercial feedlot experiment was conducted to compare performance between spayed and intact heifers fed melengestrol acetate. Intact heifers had greater ADG and tended to have greater DMI compared to spayed heifers, although no difference in feed conversion was observed. Carcass weight …

Injectable Hydrogels For Bone Regeneration: Mechanical Reinforcement Strategies Using Nanoparticles And Nanofibers: Review Paper, Fariba Ganji, Morteza Mirzagoli, Lobat Tayebi

Electrical & Computer Engineering Faculty Publications

Background and Purpose: The growing demand for bone regeneration following severe injuries highlights the importance of scaffolds in bone tissue engineering (BTE). Injectable hydrogels have emerged as promising candidates because their properties closely mimic the native extracellular matrix (ECM). However, their limited mechanical strength and structural instability restrict their practical application. Approach: This review summarizes recent strategies for reinforcing in situ-forming injectable hydrogels to improve their mechanical performance for bone regeneration. Particular emphasis is placed on nanomaterial-based strategies, including the incorporation of nanoparticles and nanofibers, and their ability to enhance the physical properties of polymeric networks. Key Results: Evidence from …

The Gut-Heart Axis: Exploring The Role Of The Gut Microbiome In Cardiovascular Health-A Focused Systematic Review, Yahya Makkieh, Haider Hussain Shah, Sakan Binte Imran, Shadman Mahmood Mahmood Khan Pathan, Anagha Chirayath Saju, Mounica Majooju, Aastha Garg, Tarun Naag, Rabeeul Islam, Cheeranthodika Fahima, Ramsha Ali

Electrical & Computer Engineering Faculty Publications

This focused systematic review examines the role of the gut microbiota in cardiovascular disease (CVD). The review explores mechanisms linking gut dysbiosis with CVD via microbial metabolites such as trimethylamine-Noxide (TMAO) and short-chain fatty acids (SCFAs), which affect inflammation, endothelial function, and lipid metabolism. Interventions including dietary modifications, probiotics, prebiotics, fecal microbiota transplantation, and pharmacological agents such as statins, rifaximin, and empagliflozin are evaluated for their impact on microbial composition and cardiovascular outcomes. Probiotic strains and fiber-rich diets demonstrated modest improvements in blood pressure, lipid profiles, and inflammatory markers. Studies revealed that gut microbiome alterations influence drug metabolism and bleeding …

Mtl_Tx: A Multi-Task Transformer Model For Improved Radiation Time-Series Estimation, Hongfang Zhang, Adam Stavola, Hal Ferguson, Bence Budavari, Hongyi Wu, Chiman Kwan, Jiang Li

Electrical & Computer Engineering Faculty Publications

Controlling radiation doses at potential radioactive facilities is critical to ensuring the safety of both personnel and the public. At the Thomas Jefferson National Accelerator Facility (JLab), multiple sensors are deployed around the three experimental halls to monitor key parameters, including single-beam current, energy levels, current leakage, and radiation values during accelerator operations. In this study, we developed a Multi-task Transformer model, MTL_TX, to accurately estimate radiation doses at sensor locations based on historical data, with the aim of enhancing safety in accelerator facilities and surrounding public areas. To improve estimation accuracy, we integrated two innovative components into the proposed …

Recent Insight And Perspective Of Marine-Inspired Biopolymers For Wound Healing Applications - A Review, Muhammad Umar Aslam Khan, Saiqa Yousaf, Abdalla Abdal-Hay, Mohd Faizal Bin Abdullah, Sahar Madani, Muhammad Shahzad Zafar, Goran M. Stojanović, Lobat Tayebi

Electrical & Computer Engineering Faculty Publications

There is an increasing necessity for advanced, sustainable, and biocompatible materials for wound healing as therapeutic and diagnostic products. Marine environments, characterized by high biodiversity, offer an underutilized source of natural resources with enormous potential for creating novel materials for dressings. This review highlights the revolutionary nature of polymeric biomaterials of marine origin, with a focus on polysaccharides, like alginate, chitosan, and carrageenan; proteins, such as collagen and gelatin. These biopolymers are outstanding in their physicochemical properties, such as biodegradability, bioactivity, and modifiable mechanical strength, which enable their use in wound-healing systems. Besides, these biomaterials may be easily chemically and …

Photobiomodulation Mitigates The Inhibitory Effects Of Pirfenidone On Cancer-Associated Fibroblasts And Their Pro-Tumorigenic Properties: A Cause For Concern, Nima Rastegar-Pouyani, Alireza Nasirpour, Fatemeh Javani Jouni, Hossein Vazini, Ahmad Moshaii

Electrical & Computer Engineering Faculty Publications

Cancer-associated fibroblasts (CAFs) within the tumor microenvironment highly contribute to cancer progression and poor prognosis. Recent findings introduce pirfenidone, a medication for pulmonary fibrosis, as a promising repurposed candidate for inhibiting CAFs. Moreover, photobiomodulation (PBM), or low-level laser therapy, has surfaced as a potential modality against cancer; however, its impact on CAFs is not thoroughly comprehended. The present study scrutinized the effects of PBM, pirfenidone, and PBM+pirfenidone on CAFs, and their consequent impact on cancer cells using the CAF-conditioned media. After treating CAFs with PBM at wavelengths 660 and 980 nm with/without PFD and then culturing cancer cells in the …

Pin-Plane Electrical Discharge Driven By A Mosfet Dc Current Source, Myles Perry, Sidmar Holoman, Daniel Wozniak, Shirshak Kumar Dhali

Electrical & Computer Engineering Faculty Publications

The generation of atmospheric pressure nonequilibrium plasma using electrical discharges is an active area of research due to its significance in a wide spectrum of applications including medicine, combustion, and manufacturing. In our attempt to create a helium plasma jet in a pin-plane discharge with a constant current source, we observed self-pulsating behavior. We present the results of the electrical, optical, and spectroscopic measurements carried out to characterize the discharge. The duration of the discharge is a few tens of nanoseconds, and the repetition rate is in the few tens of kHz. The effect of the gap distance and gas …

Recent Advances In Bioceramics, Fundamental Properties And Future Perspective In Biomedical Applications ‒ A Review, Ayesha Younas, Muhammad Umar Aslam Khan, Mohd Faizal Binte Abdullah, Lobat Tayebi, Shuanghu Wang, Abdalla Abdal-Hay, Yichi Xu

Electrical & Computer Engineering Faculty Publications

Bioceramics are important biomaterials in biomedical engineering because of their biocompatibility, bioactivity, osteoconductivity, and structural resemblance to actual bone tissue. In recent years, materials science and nanotechnology have enabled the use of bioceramics in bone regeneration, dental restoration, tissue engineering, drug delivery systems, and implantable medical devices. This comprehensive review covers advances in bioceramics, including calcium phosphates, hydroxyapatite (HAp), tricalcium phosphate, bioactive glasses, zirconia, alumina, and multifunctional ceramic nanocomposites. Priority is given to techniques such as additive manufacturing, 3D printing, sol-gel processing, electrospinning, and nanostructuring to improve mechanical strength, porosity, bioactivity, and cell interactions. Recent advances include ion doping, surface …

3d-Printed Alginate Scaffolds Incorporated With Synergistic Strontium/Magnesium - Doped Bioglass Nanoparticles For Bone Regeneration: An In Vivo Evaluation In Rabbit Cranial Defects, Mehraneh Movahedi Aliabadi, Afsaneh Jahani, Seyed Majdoddin Vahidi Toorchi, Ali Moradi, Mohammad Hossein Ebrahimzadeh, Fatemeh Kalalinia, Farkhonde Sarhaddi, Lobat Tayebi, Nafiseh Jirofti

Electrical & Computer Engineering Faculty Publications

Nonunion fractures remain a major orthopedic challenge, highlighting the need for improved bone tissue engineering (BTE) strategies. This study hypothesized that incorporating Sr/Mg-doped 58S bioglass nanoparticles into 3D-printed alginate (Alg) scaffolds would improve their physicochemical, mechanical, and biological properties and enhance bone regeneration. Structural characterization showed that Sr/Mg-doping reduced bioglass size and produced interconnected porous scaffolds. Under wet conditions, Alg scaffold incorporating 2.5%Sr/Mg-doped 58S bioglass showed the highest Young’s modulus (0.4356 ± 0.0244 MPa), whereas under dry conditions, the Alg scaffold incorporating 5%Sr/Mg-doped 58S bioglass achieved the highest value (0.1945 ± 0.0519 MPa). In vitro studies demonstrated biocompatibility and enhanced …

Standardization Of Neuromuscular Reflex Analysis—Role Of Fine-Tuned Vision-Language Model Consortium And Openai Gpt-Oss Reasoning Llm-Enabled Decision Support System, Eranga Bandara, Ross Gore, Sachin Shetty, Ravi Mukkamala, Christopher K. Rhea, Brittany S. Samulski, Amin Hass, Atmaram Yarlagadda, Shaifali Kaushik, Malith De Silva, Andriy Maznychenko, Inna Sokolowska, Kasun De Zoysa

VMASC Publications

Background/Objectives: Accurate assessment of neuromuscular reflexes, such as the Hoffmann reflex (H-reflex), plays a critical role in sports science, rehabilitation, and clinical neurology. Conventional interpretation of H-reflex electromyography (EMG) waveforms is subject to inter-rater variability and interpretive bias, limiting reliability and standardization. This study aims to develop an automated, interpretable, and robust agentic AI–driven framework for H-reflex waveform analysis. Methods: We propose a fine-tuned Vision–Language Model (VLM) consortium combined with a reasoning Large Language Model (LLM)–enabled decision support system for automated H-reflex interpretation. Multiple VLMs were fine-tuned on curated datasets of H-reflex EMG waveform images annotated with expert clinical observations, …

Machine Learning Classification Of Prostate Cancer Genomic Sequences Using K-Mer And Sequence-Derived Features, Kuldeep Rawat, Hirendra Nath Banerjee, Jamie Noble, Saa Naudia Deloatch, Satyendra Banerjee, Sachin Shetty, Soumya Banerjee

VMASC Publications

Prostate cancer disproportionately impacts African American men, who experience significantly higher mortality rates and earlier disease onset than other populations. Current diagnostic approaches, including prostate-specific antigen testing and biopsy, lack sufficient specificity and sensitivity, underscoring the need for accurate, molecular-level classification tools. This paper presents a machine learning framework for binary classification of genomic DNA sequences as cancerous or healthy. A dataset of 1684 FASTA-formatted sequences obtained from the National Library of Medicine - GenBank was analyzed, with 1662 sequences retained after quality control filtering. Feature engineering yielded 67 attributes, including GC content, Shannon entropy, sequence length, and trinucleotide k-mer …

Beyond Hereditary Xerocytosis: Chronic Hemolysis Due To A Non‑Classic Piezo1 Variant With Sickle Cell Trait As A Potential Modifier, Daniel Üblagger Md, Emily Jacobson, Beamon Agarwal Md, Phd, Jacob Troutman Do

Fellows and Residents

No abstract provided.

Developing A Portable Ultrasound Quick Guide To Enhance Point-Of-Care Training In Primary Care, Gurpreet Bharaj Md, Solomon Saul Do

Fellows and Residents

No abstract provided.