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Ariel - Volume 10 Number 2, Edward G. Zurad, Jim O'Brien, Meg Trexler, Eric Singel, Jeffrey Banyas, Al Signorella, Stuart Singer

Ariel

Executive Editors

Madalyn Schaefgen

David Reich

Business Manager

David Reich

News Editors

Medical College

Edward Zurad

CAHS

John Guardiani

World

Mark Zwanger

Features Editors

Meg Trexler

Jim O'Brien

Editorials Editor

Jeffrey Banyas

Photography and Sports Editor

Stuart Singer

Commons Editor

Brenda Peterson

New Mexico Location List Of Alumni And Former Housestaff, Unm School Of Medicine Alumni Office

University of New Mexico School of Medicine Location Report

This report relates the locations of UNM School of Medicine Alumni and Housestaff as well as other information about School of Medicine graduates.

Draize: A Blueprint For Change, Henry Spira

Draize Test Campaign

As coordinator, I prepared the following pages for the campaign to abolish the Draize rabbit blinding test. The plan includes background information, short and long range goals and step by step initiatives. This working blueprint was circulated to individuals and organizations interested in supporting the campaign. And we made a point of sharing copies of our plan with the cosmetics industry and any interested observers. It has always been our policy to have an up-front, open agenda.

The Wavelength Dependence Of Herpes Simplex Viral Inactivation & Ultraviolet Enhanced Reactivation, Richard Detsch

Masters Theses & Specialist Projects

The degrees of Ultraviolet Enhanced Reactivation (UVR) by mammalian cells of Heroes simplex virus inactivated by different wavelengths of far ultraviolet radiation were measure'. The wavelength dependence of UVR is presented for the wavelength region 238 nm to 297 nm. The shape of the UVR curve suggests that virus directed repair is less dependent on the wavelength of UV radiation than are cellular repair mechanisms. The wavelength dependence of Herpes simplex inactivation by far UV radiation is also presented. The shape of the virus inactivation curve suggests the involvement of both DNA and protein.

Effects Of Two Speeds Of Isokinetic Training On Strength, Power & Muscular Endurance, Kunle Adeyanju

Masters Theses & Specialist Projects

The purpose of this investigation was to determine the effects of two speeds of isokinetic training on muscular strength, power and endurance on college females.

The study involved thirty college females. Twenty of the subjects who served in the experimental groups were randomly assigned to one of two groups: fast speed or slow speed group. This was done after matching based on the pretest strength measure. Ten subjects who served as the control group were from a bowling class This investigation was conducted for seven weeks with a training frequency of three days per week. The experimental treatment was isokinetic …

Results-Oriented Management Though Mbo, Richard Lyders

Library Press and Events

Management by Objectives (MBO) as it has been implemented in the Houston Academy of Medicine--Texas Medical Center Library is described. That MBO must be a total management system and not just another library program is emphasized throughout the discussion and definitions of the MBO system parts: (1) mission statement; (2) role functions; (3) role relationships; (4) effectiveness areas; (5) objective; (6) action plans; and (7) performance review and evaluation. Examples from the library's implementation are given within the discussion of each part to give the reader a clearer picture of the library's actual experiences with the MBO process. Tables are …

Jefferson Alumni Bulletin – Volume Xxviii, Number 4 Summer 1979

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume XXVIII, Number 4 Summer 1979

The 38th 38 Years Later, Page 2

Jefferson Scene, Page 10

Reunion Clinic Talks, Page 19

Class Notes, Page 31

Class of 1979 Hospital Appointments, Page 45

Obituaries, Page 50

Attraction Increases And Decreases As A Function Of Emotion-Attribution And Appropriate Social Cues, Richard A. Dienstbier

Department of Psychology: Faculty Publications

To study the impact of startle-induced arousal on attraction, blindfolded subjects in a “vestibular function” study were startled by a loud noise accompanying the sudden backward tilt of the dental chair in which they were seated. In Study I startled male subjects indicated (on a “postexperimental” questionnaire) greater attraction toward a pretty female experimenter than did control subjects. Study II demonstrated the reverse, with startled male subjects disliking a male experimenter more than controls. In Study III, female subjects startled by a male experimenter indicated greater attraction than controls, although the pattern of their responses differed from males. While an …

1979 Commencement For Jefferson Medical College, College Of Graduate Studies, And College Of Allied Health Sciences

Sidney Kimmel Medical College Commencements

No abstract provided.

1979 Commencement For Thomas Jefferson University College Of Allied Health Sciences School Of Nursing

Jefferson College of Nursing Commencements

No abstract provided.

Ariel - Volume 10 Number 1, Edward G. Zurad, Madalyn Schaefgen, Paul Doghramji, Jim O'Brien, Meg Trexler, Roslyn Taylor, John Angstadt, John Guardiani, Jeffrey B. Banyas, Kathleen J. Woods, Lorri Palos, Angela Galdini, Brian Uniacke, Joel Shaffer, Steve Eaton, Scott Kennedy

Ariel

Executive Editors

Madalyn Schaefgen

David Reich

Business Manager

David Reich

News Editors

Medical College

Edward Zurad

CAHS

John Guardiani

World

Mark Zwanger

Features Editors

Meg Trexler

Jim O'Brien

Editorials Editor

Jeffrey Banyas

Photography and Sports Editor

Stuart Singer

Commons Editor

Brenda Peterson

Metcalf-Hatch Repeal Means Lab Accountability, Henry Spira

Articles

No abstract provided.

Ariel - Volume 9 Number 6, Jim Mcweeney, John P. Welch, George Winch, Steve Levine, Phillip U. Gilman, Michael X. Repka, Dick Moberg, Mark Rubin, Mark Z. Repka

Ariel

Executive Editor

Seth B. Paul

Associate Editor

Warren J. Ventriglia

Business Manager

Fredric Jay Matlin

University News

John Patrick Welch

World News

George Robert Coar

Editorials Editor

Steve Levine

Features

Mark Rubin

Sports Editor

Eli Saleeby

Photo Editor

Ken Buckwalter

Circulation

Victor Onufreiczuk

Lee Wugofski

Graphics and Art

Steve Hulkower

Commons Editor

Brenda Peterson

Ua77/1 Western Alumnus, Vol. 50, No. 4, Wku Alumni Association

WKU Administration Documents

Alumni magazine published by WKU. This issue has the following articles:

• Harrison, Lowell. Wanted: Your Memories
• Highland, Jim. Dr. John Minton Named Interim President
• An Emotion-Filled Thanks for Harriet and Dero Downing
• Armstrong, Don. C. Ray Franklin Gives Priceless Antiques for Display at Kentucky Museum
• Conway, Sheila. An Iranian Ordeal for Carlton Jackson
• Tharp, Kerry. Larry Cuzzort Blazes to Two-Mile Record
• Salato, Nancy. Speech Clinic Gets New Quarters
• Western Offers Courses for Study Abroad
• Newspaper Course Covers Death & Dying
• Grant Provides Course for Understanding Arts
• Public Relations Students Promote Financial Aid Information
• Medical Technology Students Study in Rural Areas …

A Comparison Of Traditional Grass-Twist Backstops To One Of Corrugated Cardboard Design Use On Indoor Ranges, Charles T. Crume Jr.

Masters Theses & Specialist Projects

This study presents the results of a comparison of traditional grass-twist backstops frequently used on indoor ranges with one of corrugated cardboard design. The findings indicate that the corrugated cardboard design is substantially superior.

The four factors selected for testing were:

1. Arrow pass-through levels and subsequent arrow repair costs
2. Arrow penetration levels, tested over several distances and using several bow weights
3. Arrow-stopping potential with beginning and inexperienced archers
4. Storage

Testing showed the first three factors supporting the corrugated cardboard design. The last factor, storage, was found to be about equally supportive of both designs.

Several recommendations are made. These recommendations …

Classification Of Support Staff In A Consortium Medical Library: A Case Study, Sally Pollak, Richard A. Lyders

Library Press and Events

A representative committee of Houston Academy of Medicine-Texas Medical Center Library staff and faculty, under the direction of the library administration, successfully redesigned a job classification system for the library's nonprofessional staff. In the new system all nonprofessionals are assigned to one of five grade levels, each with a corresponding salary range. To determine its appropriate grade level each job is analyzed and assigned a numerical value using a point system based on a set of five factors, each of which is assigned a relative number of points. The factors used to measure jobs are: education and experience, complexity of …

A Scale For Assessing The Severity Of Diseases And Adverse Drug Reactions: Application To Drug Benefit And Risk, Ronald J. Tallarida, Rodney B. Murray, Carl Eiben

Department of Pharmacology and Experimental Therapeutics Faculty Papers

Physicians were interviewed to assess their willingness to risk adverse drug reactions among patients. These untoward reactions were ranked according to severity and weighted against the primary illness being treated. A specially designed questionnaire in the form of a matrix was used. Severity was divided into seven classes denoted by progressively increasing numerical scores, W₁ to W₇, whose values could be calculated from analysis of the completed questionnaires. The questionnaires presented several cases, in each of which an illness of specified severity was to be treated with a drug whose untoward reactions differ in severity from that …

Jefferson Alumni Bulletin – Volume Xxviii, Number 3 Spring 1979

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume XXVIII, Number 3 Spring 1979

Guidelines for Tomorrow, Page 2

Orthopaedics at Jefferson, Page 11

The Doctor’s Wife, the Doctor, Page 15

Class Notes, Page 27

Obituaries, Page 35

Metcalf-Hatch Act: Profit, Politics And Pain, Henry Spira

Articles

No abstract provided.

Ua12/2/1 College Heights Herald Magazine, Wku Student Affairs

WKU Administration Documents

College Heights Herald Magazine, articles in this issue:

• Holman, Connie. In Search of … Graduates Face Challenge of Home Hunting
• Lyons, Mark, Fish, Tim. Feeling Good about Yourself in … the Age of Anxiety
• Pace, Mary. Books May Improve Ego
• Fish, Tim. Obesity Can Cause Loss of Self-Confidence
• Fish, Tim. Fall Guy - Laughter
• Stanton, Barb. Classroom Ramblings, poem

City Of Faith Fact Sheet (March, 1979), Holy Spirit Research Center, Oral Roberts University

City of Faith

A press release fact sheet concerning the City of Faith from March 1979 from Oral Roberts University. The fact sheet contains information on the purpose, location, space, facade, services, and facilities.

Ariel - Volume 9 Number 5, John Welch, George Coar, John W. Smith, Ii, Richard Yelovich, Mark Rubin, Roslyn Taylor, Steve Levine, John Radomski, Robert L. Brent, Vincent Viscomi, Jon Adams, Joyce Freidel, Mark Repka

Ariel

Executive Editor

Seth B. Paul

Associate Editor

Warren J. Ventriglia

Business Manager

Fredric Jay Matlin

University News

John Patrick Welch

World News

George Robert Coar

Editorials Editor

Steve Levine

Features

Mark Rubin

Brad Feldstein

Sports Editor

Eli Saleeby

Photo Editor

Ken Buckwalter

Circulation

Victor Onufreiczuk

Lee Wugofski

Graphics and Art

Steve Hulkower

Commons Editor

Brenda Peterson

In Vitro Incorporation Of Molybdate Into Demolybdoproteins In Escherichia Coli, Randolph H. Scott, George T. Sperl, John A. Demoss

Faculty, Staff and Student Publications

When Escherichia coli was grown in the presence of tungstate, inactive forms of two molybdoenzymes, nitrate reductase and formate dehydrogenase, accumulated and were converted to their active forms upon incubation of cell suspensions with molybdate and chloramphenicol. The conversion to the active enzymes did not occur in cell extracts. When incubated with [(99)Mo]molybdate and chloramphenicol, the tungstate-grown cells incorporated (99)Mo into protein components which were released from membranes by procedures used to release nitrate reductase and formate dehydrogenase and which migrated with these activities on polyacrylamide gels. Although neither activity was formed during incubation of the crude extract with molybdate, …

Special Edition 1979, Southwestern Oklahoma State University

The Sig

The Sig Newsletter from the Southwestern Oklahoma State University College of Pharmacy - Special Edition 1979

Winter 1979, Southwestern Oklahoma State University

The Sig

The Sig Newsletter from the Southwestern Oklahoma State University College of Pharmacy - Winter 1979

Early Diagnosis Of Relapse In Acute Myeloblastic Leukemia — Serologic Detection Of Leukemia-Associated Antigens In Human Marrow, Michael A. Baker , M.D., Judith A. Falk , B.Sc., Walter H. Carter , Ph.D., Robert N. Taub , M.D., Ph.D.

Internal Medicine Publications

Abstract

We tested serial bone-marrow samples from 47 adults with acute myeloblastic leukemia in remission for reactivity with heteroantiserums to leukemia-associated antigens, to determine whether imminent relapse could be detected in patients with acute leukemia. Of 26 patients who relapsed by standard morphologic criteria, 21 had increased immunoreactivity of bone marrow for one to six months (mean, 3.7 months) before relapse. High concordance was observed between a positive test and relapse during the period of study (chi-square = 27.53, P

Human Infection From An Unidentified Erythrocyte-Associated Bacterium, Gordon L. Archer , M.D., Philip H. Coleman , D.V.M., Ph.D., Roger M. Cole , M.D., Ph.D., Richard J. Duma , M.D., Ph.D., Charles L. Johnston , Jr., M.D.

Internal Medicine Publications

Abstract

A 49-year-old splenectomized man had an infection from an unidentified, gram-positive, rodshaped bacterium that adhered to the majority of his peripheral-blood erythrocytes. On transmission electron microscopy, the bacterium was seen to be extraerythrocytic and was 0.2 μm wide by 1.0 to 1.7 μm long. It possessed a thick, granular cell wall, a trilamellar membrane external to the cell wall and prominent mesosomes. Attempts to cultivate the organism in vitro or to duplicate the patient's disease in splenectomized animals were unsuccessful. The patient's response suggested that the bacterium was susceptible to cell-wall-active antibiotics and to chloramphenicol but not to tetracycline. …

A Comparison Of Amphotericin B Alone And Combined With Flucytosine In The Treatment Of Cryptoccal Meningitis, John E. Bennett , M.D., William E. Dismukes , M.D., Richard J. Duma , M.D., Gerald Medoff , M.D., Merle A. Sande , M.D., Harry Gallis , M.D., John Leonard , M.D., Branch T. Fields , M.D., Major Bradshaw , M.D., Hubert Haywood , M.D., Zell A. Mcgee , M.D., Thomas R. Cate , M.D., C. Glenn Cobbs , M.D., John F. Warner , M.D., David W. Alling , M.D., Ph.D.

Internal Medicine Publications

Abstract

We compared amphotericin B therapy for cryptococcal meningitis with a newer regimen containing both amphotericin B and flucytosine. In 50 patients with 51 courses of therapy adherent to the protocol, 27 courses were with amphotericin B and 24 with the combination. Even though the combination regimen was given for only six weeks and amphotericin B for 10 weeks, the combination cured or improved more patients (16 vs. 11), produced fewer failures or relapses (three vs. 11), more rapid sterilization of the cerebrospinal fluid (P<0.001) and less nephrotoxicity (P<0.05) than did amphotericin B alone. The number of deaths was the same (five) with each regimen. Adverse reactions to flucytosine occurred in 11 of 34 patients but were not life threatening. We conclude that combined flucytosine-amphoericin B therapy is the regimen of choice in cryptococcal meningitis. (N Engl J Med 301:126–131, 1979)

[Beta]-(2-Hydroxyphenyl)Ethanolamine Hydrochloride [2-Amino-1-(2-Hydroxyphenyl)Ethanol Hydrochloride], Alexandros Makriyannis, James B. Anderson, Joseph T. Dipiro, Edward Kostiner, Gilbert Hite

Publications from the Office of the Dean

CsH~2NO2+.C1 -, m.p. 441-449 K (from ethyl acetate), P212~2 l, a = 7.363 (2), b = 21.824 (6), c = 5.790 (2)/~, Z = 4, D x = 1.354, D m = 1.356 Mg m -3 (flotation: CC14-C6H6). The structure was solved by MULTAN. Full-matrix least-squares refinement converged to R = 0.057 for the R configuration and to R = 0.056 for the S configuration (P < 0.05). This is consistent with spontaneous resolution of the title compound, single crystals of which provided optically active aqueous solutions. A partially occupied oxygen site O(1)' is attributed to the oxidation of the alkyl hydroxyl group to a ketone during the data collection. The CI- is hydrogen bonded to H2(N)554, H3(N)555, and 1-t(O2)655 (2.37, 2-19, and 2.10 A). Both O(1) and 0(2) are internally hydrogen bonded [HI(N)...O(1), 2.41 and H(O1)...O(2) = 2.24 A]. Intramolecular hydrogen bonding may account for the unusual pharmacological properties of this compound in which only the N-C(1)-C(2)-O(1) and the O(1)-C(2)- C(3)-C(4) and O(1)-C(2)-C(3)-C(8) torsion angles (-41, -60, +122 ° ) differ significantly from those of other phenylethanolamines.

Behavioral Pharmacy, C. Anderson Johnson, Albert I. Wertheimer

CGU Faculty Publications and Research

In the text that follows, the development of a coherent and recognizable teaching and research field devoted to the development of the behavioral and social sciences in pharmacy is proposed. It is important for teachers and researchers in this field to establish a common and recognizable identity; to share basic definitions, purposes and criteria; and to develop forums (such as scientific meetings ·and perhaps a journal) for the exchange and nourishment of the behavioral science knowledge that they generate. It is suggested that this field be called behavioral pharmacy. This title is suggested primarily because Of recent· participant agreement and …