Medicine and Health Sciences Commons^™

Physical Linkage Of The Genes For Platelet Membrane Glycoproteins Iib And Iiia., Paul F. Bray, Greg Barsh, Jean-Philippe Rosa, Xue Ya Luo, Ellen Magenis, Marc A. Shuman

Cardeza Foundation for Hematologic Research

The fibrinogen receptor on human platelets is a prototypic member of the integrin family and is composed of subunit glycoproteins IIb (gpIIb) and IIIa (gpIIIa) in a 1:1 stoichiometric ratio. We have isolated cDNA clones for gpIIb and gpIIIa and localized both genes to chromosome 17. In the current study, several approaches were used to localize and map the genes for gpIIb and gpIIIa. A preliminary evaluation of subchromosomal localization was performed by using a panel of mouse-human somatic cell hybrids that contain different amounts of the long arm of human chromosome 17. Southern hybridization to the DNA of these …

Biomedical Ethics In The Soviet Union, Richard T. De George

Center for the Study of Ethics in Society Papers

*This is an abbreviated version of a paper presented first at a joint MIT-Harvard Faculty Seminar on the humanistic dimensions of Soviet Science on November 20, 1987, and then at the Western Michigan University Ethics Center on February 10, 1988. An expanded, fully documented version, under the title "Soviet Biomedical Ethics" will appear in a volume edited by Loren Graham, and tentatively entitled The Human Side of Soviet Science, Harvard University Press, 1989.

[Review Of] The Aids Challenge: Prevention Education For Young People, Robert A. Aken

Library Faculty and Staff Publications

No abstract provided.

Patterns Of Polyadenylation Site Selection In Gene Constructs Containing Multiple Polyadenylation Signals., Roger Denome, Charles Cole

Dartmouth Scholarship

We have constructed a series of plasmids containing multiple polyadenylation signals downstream of the herpes simplex virus type 1 (HSV) thymidine kinase (tk)-coding region. The signals used were from the simian virus 40 (SV40) late gene, the HSV tk gene, and an AATAAA-containing segment of the SV40 early region. This last fragment signals polyadenylation poorly in our constructs and not at all during SV40 infection. All plasmids contained the SV40 origin of replication. Plasmids were transfected into Cos-1 cells; after 48 h, cytoplasmic RNA was isolated and the quantity and 3'-end structure of tk mRNAs was analyzed by using S1 …

Population Amalgamation And Genetic Variation: Observations On Artificially Agglomerated Tribal Populations Of Central And South America, R Chakraborty, P E Smouse, J V Neel

Faculty, Staff and Student Publications

The interpretation of data on genetic variation with regard to the relative roles of different evolutionary factors that produce and maintain genetic variation depends critically on our assumptions concerning effective population size and the level of migration between neighboring populations. In humans, recent population growth and movements of specific ethnic groups across wide geographic areas mean that any theory based on assumptions of constant population size and absence of substructure is generally untenable. We examine the effects of population subdivision on the pattern of protein genetic variation in a total sample drawn from an artificial agglomerate of 12 tribal populations …

Information Interface - Volume 12, Issue 5 - October 1988, George Washington University, Himmelfarb Health Sciences Library

Information Interface (1976 - 2009)

News and information about Himmelfarb Health Sciences Library of interest to users.

Nurses Alumni Association Bulletin, Fall 1988, Alice C. Boehret, Thelma Showers Morris, Vivian I. Moyer, Frances Baker-Anderson-Crossan, Judith A. Robins, Nancy Powell, Betty Piersol, Mabel C. Prevost, Carole Rosle, Nancy Scott, Doris E. Bowman, Margaret Summers, Katherin Flickinger Aagaard

Nursing Alumni Bulletins

Alumni Meeting Calendar

Officers and Committee Chairmen

The President's Message

The Jefferson Hospital School Of Nursing Roll Of Honor

Treasurer's Report

Glimpses From An Earlier Time

Accentuate The Positive

"I Have Noticed"

Reaching A Cherished Goal

Special Achievement Award

Archives And The Nursing Experience

Happy Birthday

Fiftieth Anniversary

CAHS Alumni Directory.

Resume Of Minutes Of Alumni Association Meetings

Alumni Office News

Committee Reports

Relief Fund

Satellite

Scholarship

Social

Bulletin

Finance

Do Something

Volunteers Needed

Bequests

Have We Changed?

The Original Coal Miners Daughter Remembers

Congratulations From The Alumni Association

Luncheon Photos

The Butterfly And The Caterpillar

Forty Three Attend Fortieth …

Ua61/1 Wku Nursing Class 1988, Wku Nursing

WKU Administration Documents

Members of the 1988 nursing class: Brenda Anderson, Willa Anderson, Cindia Annis, Kaye Beckman, Patricia Bercowetz, Valeria Boyd, Brooke Campbell, Connie Campbell, Linda Clements, Carolyn Clemons, Deana Dooley, Venetta Embry, Jennifer Evans, Eva Graham, Darlene Guinn, Laura Gupton, Rebecca Hill, Lisa Johnson, Della Jones, Marla Jones, Montina Jones, Michelle Love-Baker, Donna MacDonell, Greg Mann, Sue Martin, Goldie Mathias, Kellie Moran, Jackie Pardue, William Patterson, Tami Pearson, Gayle Phillips, Deborah Plemmons, Shirlene Shaw, Tracey Shelton, Stacy Smith, Dinah Tichenor, Amy White, Teddi Willoughby and Julia Wood.

Ua12/1 Apple Tips, Vol. I, No. 1, Wku Apple

WKU Administration Documents

Newsletter created by APPLE a planned program in life enrichment regarding drug and alcohol awareness programs.

Ua66/4/2 Allied Health Department Newsletter Issue No. 2, Wku Allied Health

WKU Administration Documents

Newsletter created by and about WKU Allied Health.

Nsu Going Back May Be The Best Way Of Getting Ahead Courses, Seminars, Workshops, Conferences Fall 1998, Nova Southeastern University

Abraham S. Fischler College of Education and School of Criminal Justice College Archive

No abstract provided.

Jefferson Alumni Bulletin – Volume Xxxviii, Number 1, Fall 1988

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume XXXVIII, Number 1, Fall 1988

Admissions, Page 2

Jefferson’s Heritage, Page 11

Jefferson Scene, Page 18

Class notes, Page 21

Research With Human Subjects As A Paradigm In Teaching, Larry I. Palmer

Faculty Publications

No abstract provided.

Developmental Expression Of Pdgf, Tgf-A, And Tgf-J Genes In Preimplantation Mouse Embryos, Daniel A. Rappolee, Carol A. Brenner, Richard Schultz, David Mark, Zena Werb

Department of Obstetrics and Gynecology Research Publications

Control of growth and differentiation during mammalian embryogenesis may be regulated by growth factors from embryonic or maternal sources. With the use of single-cell messenger RNA phenotyping, the simultaneous expression of growth factor transcripts in single or small numbers of preimplantation mouse embryos was examined. Transcripts for platelet-derived growth factor A chain (PDGF-A), trans- forming growth factor (TGF)-a, and TGF- 1, but not for four other growth factors, were found in whole blastocysts. TGF-cx, TGF-(31, and PDGF antigens were detected in blastocysts by immunocytochemistry. Both PDGF-A and TGF-a were detected as maternal transcripts in the unferilized ovulated oocyte, and again …

Pentecost In Perspective 88, Oral Roberts

Oral Roberts Sermons Audio-Video

A sermon given by Oral Roberts in 1988 at the church of Bishop Norman Wagner, location unknown. Roberts recounts the development of his crusade ministry and how he integrated his crusades in the 1950s. He also talked about the City of Faith and the struggles he was facing.

[Review Of] Global Guide To Medical Lnformation, Robert A. Aken

Library Faculty and Staff Publications

No abstract provided.

Synapse, Alabama Health Libraries Association

Synapse - Newsletter of ALHeLa

This is the September, 1988 edition of the ALHeLa newsletter - Synapse.

Contents include:

• President's Column by Lisa Raines Russell (President, ALHeLA 1988)
• Calendar of events
• ALHeLA executive council meeting minutes - September 9, 1988
• ABULS update by Maureen Battistella
• Alabama Telefacsimile Network Develops by Maureen Battistella
• Badware by Mari J. Stoddard
• MLA exchange committee by Maureen Battistella
• Video services

Information Interface - Volume 12, Issue 4 - August/September 1988, George Washington University, Himmelfarb Health Sciences Library

Information Interface (1976 - 2009)

News and information about Himmelfarb Health Sciences Library of interest to users.

Adolescent Smoking Status And Socioeconomic Dependence On The Tobacco Crop In Southeastern Kentucky, Gregory Colwell

Masters Theses & Specialist Projects

The purpose of the study was to quantify the relationship between adolescent smoking and economic dependence on the tobacco crop. A survey of 1322 students from a random sample of all secondary schools in four counties in southeastern Kentucky was performed. The survey gathered information concerning smoking behavior and social variables. Chi-square analysis was performed to assess the relationships between these variables in students from families who worked with tobacco and families who did not.

Chi square analysis of female adolescent smoking behavior revealed a significant association between the instances of adolescent smoking and age, friend smoking status and sibling …

Intracranial Aneurysm-Early Diagnosis & Management, George M. Austin

The Dr. George M. Austin Neurology Research Collection

Intracranial Aneurysm-Early Diagnosis & Management

Two lectures as follows:

Intracranial Aneurysm-Early Diagnosis & Management Before Major Rupture. George M. Austin, M.D., St. Francis Hospital, August 12, 1988. 1 pg. plus chart.

Early Diagnosis and Management of Intracranial Aneurysms Prior to Rupture. George M. Austin, M.D., Santa Ynez Hospital, August 23, 1988. 1 pg.

The Gli-Kruppel Family Of Human Genes, John M. Ruppert, Kenneth W. Kinzler, Albert J. Wong, Sandra H. Bigner, Fa-Ten Kao, Martha L. Law, Hector Seuanez, Stephen J. O'Brien, Bert Vogelstein

Biology Faculty Articles

Previous characterization of GLI, a gene found to be amplified and expressed in a subset of human brain tumors, revealed the presence of five tandem zinc fingers related to those of Krüppel (Kr), a Drosophila segmentation gene of the gap class. We have used the GLI cDNA as a molecular probe to isolate related sequences from the human genome. Partial characterization of six related loci, including sequence determination, expression studies, and chromosome localization, revealed that each locus could encode a separate finger protein. The predicted proteins all had similar H-C links, i.e., a conserved stretch of 9 …

Insulin Stimulates The Dephosphorylation And Activation Of Acetyl-Coa Carboxylase., Lee A. Witters, Thomas D. Watts, Diana L. Daniels, Joseph L. Evans

Dartmouth Scholarship

The mechanism underlying the ability of insulin to acutely activate acetyl-CoA carboxylase [acetyl-CoA: carbon-dioxide ligase (ADP-forming), EC 6.4.1.2; AcCoA-Case] has been examined in Fao Reuber hepatoma cells. Insulin promotes the rapid activation of AcCoACase, as measured in cell lysates, and this stimulation persists to the same degree after isolation of AcCoACase by avidin-Sepharose chromatography. The insulin-stimulated enzyme, as compared with control enzyme, exhibits an increase in both citrate-independent and -dependent activity and a decrease in the Ka for citrate. Direct examination of the phosphorylation state of isolated 32P-labeled AcCoACase after insulin exposure reveals a marked decrease in total enzyme phosphorylation …

Camp Antagonizes Interleukin 2-Promoted T-Cell Cycle Progression At A Discrete Point In Early G1., Kirk W. Johnson, Bruce H. Davis, Kendall A. Smith

Dartmouth Scholarship

T lymphocytes are stimulated to proliferate in an autocrine/paracrine manner by the lymphokine interleukin 2 (IL-2). In seeking further insight into the mechanisms by which IL-2 induces progression of T cells through the G1 phase of the cell cycle, studies were performed with agents that increase cellular adenosine 3',5'-cyclic monophosphate (cAMP), a well-known inhibitor of lymphocyte growth. The addition of dibutyryl-cAMP, cholera toxin, forskolin, or 3-isobutyl-1-methylxanthine to an IL-2-dependent murine T-cell line evoked a dose-related suppression of S-phase transition without affecting cellular viability. Moreover, elevation of cAMP levels led to an accumulation of uniformly small cells, suggesting an arrest in …

Phloretin And Phlorizin Derivative Containing Compounds, Donald F. Diedrich, Susanne L. Diedrich

Pharmacology and Nutritional Sciences Faculty Patents

Compounds including phloretin and/or phlorizin derivatives coupled to an undigestible and non-absorbable matrix are provided. The compounds have pharmacological efficacies. They inhibit sugar uptake from the intestine and may be used in composition form in methods for treating diabetes and for promoting weight loss. A method for the manufacture of these compounds and a novel intermediate phlorizin derivative for making these compounds are also disclosed.

Foraging Patterns Of Two Syngnathid Fishes: Importance Of Harpacticoid Copepods, Kevin Tipton, Susan S. Bell

Integrative Biology Faculty and Staff Publications

The diets of juvenile (mm) Syngnathus scovelli and of Hippocampus zosterae, abundant members of a resident fish community in a Thalassia testudnum seagrass bed in Tampa Bay, Florida, were examined from Apnl to October 1984. Harpacticoid copepods comprised most of the diet, both in terms of percent number and percent biomass, for the smaller size classes of S. scovelli and for H. zosterae, and harpacticoids generally had the highest index of relative importance (IRI) for both syngnathids. S. scovelli displayed ontogenetic switching to larger food items, such as amphipods, shrimp and crustacean eggs. Harpacticus sp. 1 was the …

Summer 1988, Southwestern Oklahoma State University

The Sig

The Sig Newsletter from the Southwestern Oklahoma State University College of Pharmacy - Summer 1988

Communications Connection - Summer 1988, Nova University

Communications Connection

No abstract provided.

Ada Code Of Ethics (July 1988), American Dental Association

Code of Ethics

The ADA Code of Ethics has three main components: The Principles of Ethics, the Code of Professional Conduct and the Advisory Opinions. Contents may also include: Amendment to ADA Principles of Ethics and Code of Professional Conduct and Insert for the ADA Principles of Ethics and Code of Professional Conduct. The most current issue is available on the ADA’s website.

Jefferson Alumni Bulletin – Volume Xxxvii, Number 4, Summer 1988

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume XXXVII, Number 4, Summer 1988 Graduation and reunions, Page 2 Clinic presentations, Page 9 Jefferson scene, Page 25 Class notes, Page 35

Cigarette Advertising To Women: Taking Responsibility, Mary Guinan

School of Public Health Faculty Research

A variety of magazines are directed at American women. Some emphasize fashion, while others cover child rearing, homemaking, or gardening; still others stress career, coping with multiple women's roles, or feminism. Almost without exception, women's health concerns are periodically addressed by these magazines. Because women are the target audience, I have always assumed that these publications have women's best interests at heart. Is this a realistic assumption? I'm not sure. I also do not know what influence women's magazines have on women's health behavior, but I think it is substantial. If this is so, then shouldn't we hold these publications …