Medicine and Health Sciences Commons^™

Simian Virus 40 Host Range/Helper Function Mutations Cause Multiple Defects In Viral Late Gene Expression., Terryl Stacy, Michele Chamberlain, Charles N. Cole

Dartmouth Scholarship

Simian virus 40 (SV40) deletion mutants dlA2459 and dlA2475 express T antigens that lack the normal carboxy terminus. These mutants are called host range/helper function (hr/hf) mutants because they form plaques at 37 degrees C on BSC-1 and Vero monkey kidney cell lines but not on CV-1p monkey kidney cells. Wild-type SV40 can provide a helper function to permit growth of human adenoviruses in monkey kidney cells; the hr/hf mutants cannot. Progeny yields of hr/hf mutants are also cold sensitive in all cell lines tested. Patterns of viral macromolecular synthesis in three cell lines (Vero, BSC-1, and CV-1) at three …

Health Effects Of Air Pollutants (Sulfur Dioxide, Ozone, And Carbon Monoxide), Robert A. Bethel

Air Quality Protection in the West (November 27-28)

19 pages (includes illustrations).

Contains references.

To The U.S. Department Of Transportation: Comments Of The Environmental Defense Fund On The Secretary Of Transportation’S National Transportation Policy, Robert E. Yuhnke

Air Quality Protection in the West (November 27-28)

20 pages.

Agenda: Air Quality Protection In The West, University Of Colorado Boulder. Natural Resources Law Center

Air Quality Protection in the West (November 27-28)

Conference organizers, session moderators and/or speakers included University of Colorado School of Law professor Mark S. Squillace.

Visibility, acid rain, air toxics, and urban air pollution are the topics of an upcoming Center conference on air quality in the West. The conference will be held at the School of Law in Boulder on November 27-28, 1989. Presentations will describe the nature and scope of the issues, the existing legal framework and experience with its implementation, and proposed changes in the law. Emphasis will be placed on air quality issues in the West and efforts underway to address these problems. Special …

Toxic Air Pollution: New Solutions To Old Problems, Devra Lee Davis, Curtis Moore

Air Quality Protection in the West (November 27-28)

12 pages.

Complex Motor Dynamics And Control In Multi-Looped Negative Feedback Systems, Anne Beuter, John Milton, Christiane Labrie, Leon Glass

WM Keck Science Faculty Papers

Experiments were performed in normal and Parkinsonian subjects who were asked to maintain a constant finger position using time-delayed visual feedback. The finger position showed complex dynamics, with characteristic differences between normal and Parkinosonian subjects. Here we discuss some of the theoretical issues that must be resolved in order to understand the mechanisms that underlie the generation of these complex signals.

Information Interface - Volume 13, Issue 6 - November/December 1989, George Washington University, Himmelfarb Health Sciences Library

Information Interface (1976 - 2009)

News and information about Himmelfarb Health Sciences Library of interest to users.

Significance Of Premature Stop Codons In Env Of Simian Immunodeficiency Virus, Toshiaki Kodama, Dawn P. Wooley, Yathirajulu M. Naidu, Harry W. Kestler Iii, Muthiah D. Daniel, Yen Li, Ronald C. Desrosiers

Neuroscience, Cell Biology & Physiology Faculty Publications

The location of the translational termination codon for the transmembrane protein (TMP) varies in three infectious molecular clones of simian immunodeficiency virus from macaques (SIV_mac). The SIV_mac251 and SIV_mac142 infectious clones have premature stop signals that differ in location by one codon; transfection of these DNAs into human HUT-78 cells yielded virus with a truncated TMP (28 to 30 kilodaltons [kDa]). The SIV_mac239 infectious clone does not have a premature stop codon in its TMP-coding region. Transfection of HUT-78 cells with this clone initially yielded virus with a full-length TMP (41 kDa). …

Comparisons Of Cutoff And Regression-Based Definitions Of Reading Disabilities, J. M. Fletcher, K. A. Espy, D. J. Francis, K. C. Davidson, B. P. Rourke, S. A. Shaywitz

Developmental Cognitive Neuroscience Laboratory: Faculty Publications

Investigated specificity in reading disability by comparing 2 approaches to defining and selecting children with reading disabilities. One approach defined reading disability according to cutoff scores representing appropriate levels of intelligence and reading deficiency, whereas the other approach adjusted these scores for their intercorrelation through regression procedures. Results reveal differences in which of 1,069 children (aged 9-14 yrs) were identified as reading disabled, depending on the definition used. However, differences in neuropsychological performance between Ss whose reading scores were discrepant or not discrepant with their IQ scores were small and nonspecific for both definitions.

Neurological Problems Of Older Retired People, Lecture 9, George M. Austin

The Dr. George M. Austin Neurology Research Collection

Neurological Problems of Older Retired People. George Austin. Lecture 9 (November 1989). 2 pg. With Handwritten lecture notes, 3 yellow lined sheets as additional files.

Linker Insertion Mutants Of Simian Virus 40 Large T Antigen That Show Trans-Dominant Interference With Wild-Type Large T Antigen Map To Multiple Sites Within The T-Antigen Gene., Jiyue Y. Zhu, Charles N. Cole

Dartmouth Scholarship

Linker insertion mutants affecting the simian virus 40 (SV40) large tumor (T) antigen were constructed by inserting a 12-base-pair oligonucleotide linker into restriction endonuclease cleavage sites located within the early region of SV40. One mutant, with the insertion at amino acid 5, was viable in CV-1p and BSC-1 cells, indicating that sequences very close to the amino terminus of large T could be altered without affecting the lytic infection cycle of SV40. All other mutants affecting large T were not viable. In complementation assays between the linker insertion mutants and either a late-gene mutant, dlBC865, or a host range/helper function …

Occupational Therapy In Early Intervention: A Family-Centered Approach., Roseann C. Schaaf, L L. Mulrooney

Department of Occupational Therapy Faculty Papers

This article describes a framework for occupational therapy service provision in early intervention settings and presents pilot data aimed at examining the framework's effectiveness. The Family-Centered Framework for Early Intervention is a synthesis of concepts from the Model of Human Occupation (Kielhofner & Burke, 1980) and from the literature on play. It encompasses a systematic, holistic approach that considers the child and the family within the context of their life environments. In this framework, play is used both as an evaluative tool and as an intervention modality that addresses the volition, habituation, and performance of the child and family as …

Qualitative Metabolism Assessment Using High Performance Thin Layer Chromatography, Shih-Ling Chang

Veterinary Science Faculty Patents

A method for the qualitative assessment of oxidative drug metabolism deficiencies, preferably for the qualitative assessment of dextromethorphan metabolism, in a subject comprises analyzing a sample fluid from the subject, for example urine, which contains metabolites of a probe drug using high performance thin layer chromatography.

1989 Scholars And Artists Bibliography, Michael Schwartz Library, Cleveland State University, Friends Of The Michael Schwartz Library

Scholars and Artists Bibliographies

This bibliography was created for the annual Friends of the Michael Schwartz Library Scholars and Artists Reception, recognizing scholarly and creative achievements of Cleveland State University faculty, staff and emeriti

Ua12/2/1 College Heights Herald, Vol. 65, No. 19, Wku Student Affairs

WKU Administration Documents

WKU campus newspaper reporting campus, athletic and Bowling Green, Kentucky news. This issue contains articles:

• Hernes, Thomas. Officials Seek Gift for Recreation Center – Preston Health & Activities Center
• Lawson, Jamie. Graduate Ron Jerrell Tells 400 His Story of AIDS
• Summers, Kaye & Allison Tutt. Hilltopper Athletic Foundation Raises Support, $660,000
• Summers, Kaye & Allison Tutt. Students, School Lend Services to Athletics
• Eugene Evans to Outline Goals at Open Forum
• Potter Lot Closed Until Tomorrow
• University Logo to be Unveiled Today
• Kinslow, Gina. Central Women Get Tucked In – Minton Hall, Barnes-Campbell Hall
• Green, Travis. Associated Student Government Wants AIDS …

Fall 1989, Southwestern Oklahoma State University

The Sig

The Sig Newsletter from the Southwestern Oklahoma State University College of Pharmacy - Fall 1989

Information Interface - Volume 13, Issue 5 - October 1989, George Washington University, Himmelfarb Health Sciences Library

Information Interface (1976 - 2009)

News and information about Himmelfarb Health Sciences Library of interest to users.

Nurses Alumni Association Bulletin, Fall 1989, Alice C. Boehret, Margaret Summers, Julie S. Berkowitz, Grace Bird Petersen, Frances Baker Anderson Crossan, Nancy S. Brainard, Mary Pavulak Swan, Dorothy Mogle Forshey, Susan M. Heighway, Susan Kidd-Webster, Polly Snodgrass, Nancy Powell, Betty Piersol, E Nancy Scott, Mabel C. Prevost, Dorisq E. Bowman, Caroline Masuda, Dolores Schumann

Nursing Alumni Bulletins

Alumni Meeting Calendar

Officers and Committee Chairmen

The President's Message

Treasurer's Report

1937 Nurses' Alumnae Association Relief Fund AGREEMENT

Decade Fund

Rediscovery of a Rare Antiquity at Jefferson

Looking Backward 50 Years

"Jeff" Memories

When You're the Patient

Bee Happy

Nursing on an Indian Reservation

Supporting Parents With Mental Retardation

News about Our Graduates

Happy Birthday

Fiftieth Anniversary

Resume of Minutes of Alumni Association Meetings

Bequests

Alumni Office News

Committee Reports

Bulletin

By-Laws

Relief Fund

Satellite

Scholarship

Social

Finance

For All Born Before 1940

Stress Diet & Diet Rules

In Memoriam, Names of Deceased Graduates

Class News

Luncheon Photos

Take …

Surrogate Parenting Legislation In Michigan: Background And Review, Lucille S. Taylor

Center for the Study of Ethics in Society Papers

This essay originated in symposium presentations made to the WMU Center for the Study of Ethics in Society, January 20, 1989.

Ua61/1 Wku Nursing Class 1989, Wku Nursing

WKU Administration Documents

Members of the 1989 nursing class: Tammy Bearden, Cathy Born, Kendra Bradford, Beverly Burden, Monica Clark, Sandi Clark, Bojuana Clements, Lois Copley, Rita Cranfill, Dee Dee Croghan, Susan Daniels, Mary Doyle, Bonnie Ellis, Vicki Faulkner, Leanna Gipson, Anita Glass, Annette Hix, Becky Inghram, Nova Jackson, Pamela Jaggers, Betty Johnson, Phyllis Lawson, Kim Lile, Debbie Mann, Wanda May, Angie McCoy, Laura McMillon, George Miller, Danissa Mudd, Cynthia Nichols, Jennifer Payne, Heidi Robinson, Cindy Rose, Bonnie Sanders, Julie Sharer, Kathy Slinker, Kathy Smith, Denise Stinson, Millard Taylor, Scharme Taylor, Amelia Thompson, LaChiel Thompson, Kathy Tinsley, Shirley Wilson and Sandra Wood.

Ua66/13/3 Newsletter, Wku Health & Safety

WKU Administration Documents

Newsletter created by and about the WKU Health & Safety department.

Surrogate Parenting And Fundamental Rights, Paul J. Denenfeld

Center for the Study of Ethics in Society Papers

This essaya originated in symposium presentations made to the WMU Center for the Study of Ethics in Society, January 20, 1989.

Surrogate Parenting: The Michigan Legislation, Lucille Taylor, Paul Denenfeld

Center for the Study of Ethics in Society Papers

Surrogate Parenting: The Michigan Legislation essays by: Lucille Taylor Paul Denenfeld. These essays originated in symposium presentations made to the WMU Center for the Study of Ethics in Society, January 20, 1989. Lucille Taylor is Majority Counsel, Michigan State Senate Paul Denenfeld is Legal Director, ACLU Fund of Michigan

Ua66/13/4 The Ahec Vision, Vol. 1, No. 1, South Central Kentucky Ahec

WKU Administration Documents

Newsletter created by and about the South Central Kentucky Area Health Education Center.

Jefferson Alumni Bulletin – Volume Xxxix, Number 1, Fall 1989

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume XXXIX, Number 1, Fall 1989 State of the College, Page 2 President’s Club honors university benefactors, Page 7 Everest: pain and accomplishment, Page 11 Resurgence of interest in Jefferson history, Page 14 Robert L. Brent, M.D., Ph.D. is honored, Page 18 Class notes, Page 23

Osteogenesis Imperfecta. The Position Of Substitution For Glycine By Cysteine In The Triple Helical Domain Of The Pro Alpha 1(I) Chains Of Type I Collagen Determines The Clinical Phenotype., Barbra J. Starman, David Eyre, Harry Charbonneau, Maria Harrylock, Mary Ann Weis, Lester Weiss, John M. Graham Jr., Peter H. Byers

Dartmouth Scholarship

Skin fibroblasts grown from three individuals with osteogenesis imperfecta (OI) each synthesized a population of normal type I collagen molecules and additional molecules that had one or two alpha 1(I) chains that contained a cysteine residue within the triple-helical domain, a region from which cysteine normally is excluded. The patients had very different phenotypes. One patient with OI type I had a population of alpha 1(I) chains in which glycine at position 94 of the triple helix was substituted by cysteine; a patient with OI type III had a population of alpha 1(I) chains in which glycine at position 526 …

The Safety Of Maximal Exercise Testing, Larry W. Gibbons, Steven N. Blair, Harold W. Kohl Iii, Kenneth H. Cooper

Faculty Publications

Previous reports on the safety of exercise testing have been based on surveys from different testing facilities with a variety of testing protocols and patient types. From 1971 through 1987, 71,914 maximal exercise tests conducted in a population with a low prevalence of known coronary heart disease under uniform conditions at a single medical facility resulted in six major cardiac complications including one death. No complications have occurred in the past 10 years in 45,000 maximal tests. The overall cardiac complication rate in men and women is 0.8 complications per 10,000 tests with 95% confidence intervals of 0.3-1.9 complications per …

Embryonic Chicken Fibroblast Collagen Binding Proteins: Distribution, Role In Substratum Adhesion, And Relationship To Integrins, Roy C. Ogle, A. Jeannette Potts, Marchall Yacoe, Charles D. Little

School of Medical Diagnostics & Translational Sciences Publications

Collagen binding proteins (CBP) are hydrophobic, cell surface polypeptides, isolated by collagen affinity chromatography. Antibodies to CBPs inhibit the attachment of embryonic chicken heart fibroblasts to native type I collagen fibrils in a dose-dependent manner. The CBP antibodies also induce rounding and detachment of cells adherent to a planar substratum. This process of antibody-mediated substratum detachment resulted in a clustering of CBP and cell-associated extracellular matrix at the cell surface, and the rearrangement of filamentous actin. Other functional studies showed that cells grown within a three-dimensional gel of type I collagen cannot be immunostained at the cell surface with CBP …

Self-Esteem, Spiritual Well-Being, And Intimacy: A Comparison Among Couples Using Nfp And Oral Contraceptives, Richard J. Fehring, Donna M. Lawrence, Catherine M. Sauvage

College of Nursing Faculty Research and Publications

The purpose of this study was to compare the intimacy, spiritual well being (SWB), and self-esteem of couples using natural family planning (NFP) with those couples using oral contraceptives (OCs). 22 couples who were using the Creighton Model Ovulation Method of NFP for 1 year to avoid pregnancy were matched with 22 couples who were using OCs for a least a 1-year period and administered a SWB, self-esteem, and intimacy inventory. Student t-tests were calculated to determine differences in the mean scores of the 3 inventories between the 2 groups. The results showed that the NFP couples had statistically higher …

Ua68/10/1 Dare In Nashville Schools 1988-89, John Faine

WKU Administration Documents

This report summarizes the results of a partial evaluation of the 1988-89 Drug Abuse Resistance Education (DARE) effort implemented in all sixth grades in the Nashville, Tennessee, Metropolitan Public School system by trained instructors from the Nashville Metropolitan Police Department. As documented in the following pages, the evaluation effort had two major components.

1. An evaluation of the program by teachers and principals in all the participating schools.

2. Inner-City Study, an investigation designed to assess the impact of the program in elementary and middle schools that service those students thought to be most at risk to the threat of …