Medicine and Health Sciences Commons^™

Trends And Issues In Health Education Curriculum, Larry K. Olsen, Beverly S. Mahoney

Faculty Publications and Presentations

No abstract provided.

Basic Fibroblast Growth Factor And Fibroblast Growth Factor Receptor I Are Implicated In The Growth Of Human Astrocytomas., R S Morrison, F Yamaguchi, H Saya, J M Bruner, Alan M. Yahanda Md, Facs, L A Donehower, M Berger

PCI Publications and Projects

Malignant astrocytomas are highly invasive, vascular neoplasms that comprise the majority of nervous system tumors in humans. A strong association has previously been made between malignancy in human astrocytic tumors and increased expression of certain fibroblast growth factor (FGF) family members, including basic and acidic FGF. The influence of endogenous basic FGF on glioblastoma cell growth in vitro was evaluated using basic FGF-specific antisense oligonucleotides. These studies indicated that human glioblastoma cell growth in vitro, can be inhibited by suppressing basic FGF expression. Human astrocytomas also exhibited changes in FGF receptor (FGFR) expression during the course of their progression from …

Anaemia In Pregnancy - Its Cause In The Underprivileged Class Of Karachi, Saadiya Aziz Karim, Mohammad Khurshid, A.M. Memon, Sadiqua N. Jafarey

Section of Haematology/Oncology

A prospective study of the frequency and type of anaemia amongst poor urban parturients of Karachi was done. It was performed at 2 large teaching hospitals over the time span January to September, 1990. Out of 318 women studied, 104(32.7%) were anaemic (Hb levels <10gm/dl). The type of anaemia was assessed. Iron deficiency predominated and was seen amongst 63.5% of the anaemic population. There was an even distribution of other kinds of anaemia amongst the remainder of the population

Cardiovascular Risk Factors In School Children From Low Middle Income Families In Karachi, Pakistan, Salma H. Badruddin, A. Molla, Mohammad Khurshid, S. Vaz, S. Hassanali

Section of Haematology/Oncology

Serum levels of total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C) and trigly cerides (TG) were determined on 239 school children aged 5-19 years belonging to lower middle class families. The mean TC, LDL-C, HDL-C and TG ranged from 3.70-4.37 mmol/L, 2.17- 2.70 mmol/L, 0.94-1.14 mmol/L, 1.07-1.26 mmol/L respectively. In general, girls had higher TC, LDL-C and HDL-C levels. There was no significant difference in the TG levels between boys and girls. Thirty-three percent of the girls and 22% of the boys had TC level _4.4 mmol/L, the level at which dietary intervention is recommended …

Abortion/Reproductive Rights, Sandra S. Klein

Journal Articles

The issue of a woman's right to choose whether or not to continue with a pregnancy has proven to be complicated for many reasons, not the least of which is the implications for a person's right to do with her body as she sees fit. The bibliography that follows provides the researcher with an in depth look at this issue, with an emphasis on the privacy aspects.

The Changing Nature Of The Bioethics Movement, Sandra H. Johnson

All Faculty Scholarship

Commemorating the thirtieth anniversary of the field of bioethics, this article analyzes the future of bioethics by identifying its role in intellectual history and classifying stages of its development.

Part I considers the formative role of Quinlan, where the New Jersey Supreme Court held that the withdrawal of medical treatment is legally permissible under some circumstances. Quinlan and its progeny established a legal framework for life-sustaining treatment decisionmaking, affirming the use of substituted judgment or best interests standards.

In Part II the article documents the framework shift brought by Cruzan, a high-profile case challenging a family’s authority to make medical …

Pattern Of Dyslipoproteinemia In Selected Population Of Karachi, Erum Khan, Ayesha Molla, Naila Kayani, Mohammad Khurshid

Department of Pathology and Laboratory Medicine

Pattern of dyslipoproteinemia was studied ,over a period of 3-1/2 years in 487(394 males, 93 females) cases aged 4 to above 70 years. Type IV hyperlipoproteinemia was most prevalent (36%) followed by type V (15%)

A View Of Hiv--Infection In Karachi, Naila Kayani, Aamir Sheikh, Asif Khan, Chhotoobhai Mithani, Mohammad Khurshid

Department of Pathology and Laboratory Medicine

A prospective study on the prevalence of HIV-l infection in Karachi, Pakistan was conducted over a period of six years (1986-1992). Over 15,000 individualsamples and more than 32,000 donor units of individuals residing in Karachi at the time of sample co llection were tested for HIV-I infection by our screening test EIA which revealed a positivity rate of 0.23% and 0.003% in individual and donor units respectively by Western Blot. We divided patients into four groups A,B,C and D based on the most plausible cause of transmission. The largest number of positive patients belonged to group B, who were of …

Outcomes Assessment In Health Care Reform: Promise And Limitations, Wendy K. Mariner

Faculty Scholarship

If the fundamental goals of the health care reform effort are to ensure universal access to an acceptable quality of health care at an affordable cost, then the threshold question for reform is: What health care services should be provided in an efficient, equitable system?

Answering this question requires weighing a complex mix of medical and social policy factors, a process not attempted in this article. But the starting point for that process should be determining what health care services “work” and what they cost. Outcomes assessment holds considerable promise in finding answers to these subsidiary questions, because it is …

Managed Competition, Integrated Delivery Systems And Antitrust, Thomas L. Greaney

All Faculty Scholarship

A central question confronting proponents of managed competition during the health reform debate in 1994 was whether competitive networks or integrated delivery systems would emerge. Under reformers’ vision, controlling costs depended on the emergence of a sufficient number of efficient and viable integrated delivery systems. Conversely, if one or a few integrated networks dominate the market for physician or hospital services, rivalry on the main issues of health care cost control would likely dissipate. This article argues that vigilant and sensible antitrust enforcement was also a prerequisite for the success of the managed competition model. Despite the considerable emphasis on …

Laboratory Tests Of A Motivational-Perceptual Model Of Conflict Escalation, Bill E. Peterson, David G. Winter, Richard M. Doty

Psychology: Faculty Publications

We present a model suggesting that international conflicts escalate to violence when countries (a) express higher levels of power motive imagery, (b) exaggerate levels of perceived power motive imagery in communications and statements from the “other” side, and (c) express still higher levels of power motive imagery as a result of such exaggerated perceptions. The model is supported by three studies. In the first two, participants wrote replies to one of two versions of the same letter taken from a real crisis. The third study explored conditions that affect the exaggerated perception of power motive imagery of the other side …

Ua66/14/3 Nursing Pinning Ceremony, Wku Nursing

WKU Administration Documents

Pinning ceremony program listing graduates of the WKU Nursing program.

Ua12/12 Preston Center News, Vol. 2, Issue 2, Wku Intramural & Recreational Sports

WKU Administration Documents

Newsletter created by the Preston Center regarding services and intramural sports.

Ua66/14/4 Kentucky Partnership Newsletter, Vol. 1, No. 6, Kentucky Partnership For Farm Family Health & Safety

University Organizations

Newsletter created by and about the Kentucky Partnership for Farm Family Health & Safety.

Severe Bone Marrow Suppression In A Patient With Rheumatoid Arthritis On Methotrexate, M P. Iqbal, A A. Ali, A A. Alvi

Department of Biological & Biomedical Sciences

No abstract provided.

Induction Of Protective Immunity Against Larval Onchocerca Volvulus In A Mouse Model., A. M. Lange, W. Yutanawiboonchai, J. B. Lok, M. Trpis, D. Abraham

Department of Microbiology and Immunology Faculty Papers

BALB/cBYJ mice were immunized against larval Onchocerca volvulus by subcutaneous injection of normal, irradiated, or freeze-thaw-killed Onchocerca sp. larvae. The mice received challenge infections of O. volvulus third-stage larva (L3) contained in diffusion chambers implanted subcutaneously. At two-weeks postinfection, the diffusion chambers were removed and larval survival was assessed. When mice were immunized a single time with 35-krad-irradiated or normal O. volvulus L3, there was a significant reduction in the survival of challenge parasites. However, there was little or no reduction in challenge worm survival when mice were immunized a single time with freeze-thaw-killed O. volvulus L3 or fourth-stage larva …

Social Response To The Second "A" Alert Of The Parkfield Earthquake Prediction Experiment, Paul W. O'Brien

FMHI Publications

No abstract provided.

Grammatical Morpheme Acquisition In 4-Year-Olds With Normal, Impaired, And Late-Developing Language, Rhea Paul, Sally Alforde

Communication Disorders Faculty Publications

The production of the grammatical morphemes studied by Brown and his colleagues was examined in free speech samples from a cohort of 4-year-olds with a history of slow expressive language development (SELD) and a control group of normal speakers. Results suggest that children with SELD acquire morphemes in an order very similar to that shown in previous acquisition research. Children who were slow to begin talking at age 2 and who continued to evidence delayed expressive language development by age 4 showed mastery of the four earliest acquired grammatical morphemes, as would be expected, based on their MLUs, which fell …

Use Of Yeast Artificial Chromosomes (Yacs) For Studying Control Of Gene Expression: Correct Regulation Of The Genes Of A Human Beta-Globin Locus Yac Following Transfer To Mouse Erythroleukemia Cell Lines., Kenneth Peterson, Galynn Zitnik, Clare Huxley, Christopher Lowrey

Dartmouth Scholarship

We demonstrate that transfer of a yeast artificial chromosome (YAC) containing 230 kb of the human beta-globin locus into mouse erythroleukemia cells by fusion results in correct developmental regulation of the human beta-like globin genes. Additionally, we show that early after hybrid formation, human embryonic epsilon- and fetal gamma-globin genes are coexpressed with the adult beta gene but that after 10-20 weeks in culture, globin gene expression switches to predominantly adult. Thus, in contrast to shorter gene constructs, the globin genes of the beta-globin locus YAC are regulated like the chromosomal globin genes. These results indicate that transfer of YACs …

Dynamic Decision Modeling In Medicine: A Critique Of Existing Formalisms, Tze-Yun Leong

Research Collection School Of Computing and Information Systems

Dynamic decision models are frameworks for modeling and solving decision problems that take into explicit account the effects of time. These formalisms are based on structural and semantical extensions of conventional decision models, e.g., decision trees and influence diagrams, with the mathematical definitions of finite-state semi-Markov processes. This paper identifies the common theoretical basis of existing dynamic decision modeling formalisms, and compares and contrasts their applicability and efficiency. It also argues that a subclass of such dynamic decision problems can be formulated and solved more effectively with non-graphical techniques. Some insights gained from this exercise on automating the dynamic decision …

Urban American Indian Health Programs Profile, American Indian Health Care Association

Native Health Database Full Text

In response to the needs of the growing urban Indian population, this report identifies the Indian Health Service (IHS)-funded urban Indian health programs, providing an overview of the program and the services offered.

Interaoperative Frozen Section Consultation: An Analysis Of Accuracy In A Teaching Hospital., Farrukh Aijaz, Suhail Muzaffar, Akbar Shah Hussainy, Shahid Pervez, Sheema H. Hasan, Hizbullah Sheikh

Department of Pathology and Laboratory Medicine

This Is a retrospective quality assurance study of all frozen sections done at The Aga Khan University Hospital during a six year period (1986 to 1991). There were 1,031 frozen sections out of a cumulative total of 42,985 surgical specimens (2.39%). Nine hundred and seventy-six (94.66%) were concordant. In 92(8.9%) fresh specimens were brought from other hospitals of Karachi, in 37 cases (3.58%) the diagnosis was deferred till the evaluation of permanent paraffin sections and 18 (1,74%) were discordant with 7 (0.67%) false positive and 11(1,06%) false negative. Among the discordant cases, 9 were attributed to misinterpretation, 7 due to …

A Roundtable Conference On The Traditional Cultural Advocacy Program, Indian Health Service, Office Of Program Planning, Evaluation, And Legislation

Native Health Database Full Text

This report presents results of a two-day Traditional Cultural Advocacy Program (TCAP) Roundtable Conference. The purpose of the TCAP Roundtable was to develop a consensus of the IHS roles and responsibilities in addressing traditional cultural beliefs, values, and practices; and to discuss and identify issues on holistic beliefs in health care as it relates to traditional culture.

Photograph - Me 'N Susie Reception (Image 02), Morehead State University. Office Of Communications And Marketing

Louise Caudill Oral History Collection

Photograph of the reception on opening night of the play "Me 'n Susie" on November 12, 1993.

Photograph - Me 'N Susie Reception (Image 18), Morehead State University. Office Of Communications And Marketing

Louise Caudill Oral History Collection

Photograph of the reception on opening night of the play "Me 'n Susie" on November 12, 1993.

Photograph - Me 'N Susie Reception (Image 40), Morehead State University. Office Of Communications And Marketing

Louise Caudill Oral History Collection

Photograph of the reception on opening night of the play "Me 'n Susie" on November 12, 1993.

Photograph - Me 'N Susie Reception (Image 01), Morehead State University. Office Of Communications And Marketing

Louise Caudill Oral History Collection

Photograph of the reception on opening night of the play "Me 'n Susie" on November 12, 1993.

Photograph - Me 'N Susie Reception (Image 33), Morehead State University. Office Of Communications And Marketing

Louise Caudill Oral History Collection

Photograph of the reception on opening night of the play "Me 'n Susie" on November 12, 1993.

Photograph - Me 'N Susie Reception (Image 45), Morehead State University. Office Of Communications And Marketing

Louise Caudill Oral History Collection

Photograph of the reception on opening night of the play "Me 'n Susie" on November 12, 1993.

Photograph - Me 'N Susie Reception (Image 37), Morehead State University. Office Of Communications And Marketing

Louise Caudill Oral History Collection

Photograph of Susie Halbleib at the reception on opening night of the play "Me 'n Susie" on November 12, 1993.