Medicine and Health Sciences Commons^™

Global Connections In A Changing World: Romanian And U.S. Nurses Unite, Mary G. Schaal, Molly A. Rose, Ann Doherty, Adriana Vilan

College of Nursing Faculty Papers & Presentations

This article describes an international, interdisciplinary, university partnership project to collaborate with health professionals in the city of Cluj-Napoca, Transylvania, Romania, to improve the health status of Romanian workers. Academic and service-based public health nurses from the United States used the model of community competence in outlining the nursing aspect of the project. This model guided the assessment, objectives, collaborative activities, and the outcome evaluation of the project. The dimensions of the model (e.g., commitment, self-other awareness, articulateness, conflict accommodation, management of relations with larger society, and leadership) were used within the context of the political and social environment of …

Genomic Structure Of Murine Mitochondrial Dna Polymerase-Gamma., Justin L. Mott, Grace Denniger, Steve J. Zullo, H. Peter Zassenhaus

Journal Articles: Biochemistry & Molecular Biology

We have sequenced a genomic clone of the gene encoding the mouse mitochondrial DNA polymerase. The gene consists of 23 exons, which span approximately 13.2 kb, with exons ranging in size from 53 to 768 bp. All intron-exon boundaries conform to the GT-AG rule. By comparison with the human genomic sequence, we found remarkable conservation of the gene structure; the intron-exon borders are in almost identical locations for the 22 introns. The 5' upstream region contains approximately 300 bp of homology between the mouse and human sequences that presumably contain the promoter element. This region lacks any obvious TATA domain …

Unlv Magazine, Barbara Cloud, Donna Mcaleer

UNLV Magazine

No abstract provided.

Clinical Spectrum Of Systemic Lupus Erythematosus At The Aga Khan University Hospital., K. Sulaiman, N. Sohail, A. A. Sheikh, F. Raza, F. Shahzad, A. Siddique, T. Shakir, Fauziah Rabbani

Community Health Sciences

BACKGROUND:

Systemic lupus erythematosus is a disease of unknown etiology, which at onest may involve only one organ system or be multisystemic. The aim of our study is to determine the clinical presentation of SLE patients presenting to AKUH to establish whether guidelines laid down about this disease are in agreement with our experience.

METHODS:

A retrospective log review was carried out at AKUH, based on data obtained from 165 files of individuals admitted to the hospital over a period of 12 years with a confirmed diagnosis of SLE.

RESULTS:

From the sample size of 165, 143 (86.7%) were females …

Dna Ploidy Analysis Of Borderline Epithelial Ovarian Tumours, Saba Lodhi, Sabeen Najam, Shahid Pervez

Department of Pathology and Laboratory Medicine

Objective: Borderline epithelial ovarian tumors not uncommonly pose a great difficulty to surgical pathologists as morphologically they may show very similar features as those of malignant epithelial tumors except invasion. However it is important to separate these from their invasive counterparts because of their superior prognosis. Recently, attention has been focussed on the prognostic value of flow cytometric analysis of DNA ploidy in borderline epithelial ovarian tumors. The purpose of this study is to investigate whether flow cytometric analysis of cellular DNA content acts as a useful adjunct to the histopathological diagnosis of borderline malignancy.

Materials and Methods: Fifteen histologically …

A Comparative Study Of Positive Pressure Ventilation Via Laryngeal Mask Airway And Endotracheal Tube, A Idrees, F A. Khan

Department of Anaesthesia

Objective: To investigate the use of Laryngeal Mask Airway (LMA) and its comparison with the endotracheal tube for positive pressure ventilation.SETTING: A tertiary care teaching hospital.Methods: Fifty adult ASA I and II patients undergoing peripheral limb surgery were randomly allocated to 2 groups for LMA or endotracheal tube insertion. A standardized anaesthetic technique was used. The groups were then compared regarding haemodynamic changes on insertion as well as removal of LMA and ETT and any complications that occurred were noted.Results: The haemodynamic response to insertion was significantly attenuated (p < 0.05) in LMA group as compared to ETT group. The cardiovascular response to extubation was not significantly different between the groups. A higher incidence of coughing and mild hypoxaemia at extubation was noted in ETT group as compared to LMA group (p < 0.05) and blood was detected in 4 cases after LMA removal.CONCLUSION: It is concluded that the use of LMA during positive pressure ventilation is safe in selected cases. There is an attenuated haemodynamic response to insertion of LMA as compared to endotracheal tube which will be beneficial in certain patients e.g., those with ischaemic heart disease, vascular disease and hypertensives.

Non-Small Cell Lung Cancer: Disease Spectrum And Management In A Tertiary Care Hospital, M R. Khan, S B. Hasan, S A. Sami

Department of Surgery Docs

Objectives: To review the spectrum of presentation and the surgical management of Non Small Cell Lung Cancer (NSCLC) and the role of various diagnostic modalities in predicting the post-operative stage and the correlation of the post-operative stage with the chances of recurrence.SETTINGS: The Aga Khan University Hospital, Karachi--a tertiary care referral center in Paksitan.Methods: This is a retrospective study of medical records of all the patients who were managed at the Aga Khan University Hospital (AKUH) between 1988 and 1998. The patients with a diagnosis of lung cancer were identified using the ICD-9-CM coding system and the data was analyzed …

Why Has So Little Changed In Maternal And Child Health In South Asia?, Z A. Bhutta

Department of Paediatrics and Child Health

No abstract provided.

Drug Combo Winning War On Rejection: Qeii Doctors Getting Amazing Results With Fk506, Rapamycin, Ann Graham-Walker

Data and Test Instruments

A Nova Scotia organ transplant unit is beating the odds on tissue rejection, with a dramatic new drug approach.

Schip In The Formative Years: An Update, Judith D. Moore

National Health Policy Forum

This issue brief examines the status of the State Children's Health Insurance Program (SCHIP) three years after authorizing legislation was enacted. Topics addressed include enrollment and retention of children in new programs, funding allotments and expenditures, evaluation activities planned and underway, the interaction of Medicaid and SCHIP, and problems common across many states.

Combination Anti-Leukimic Therapy By Utilizing Suramin And Biologic Response Modifiers, Michael A. Doukas

Internal Medicine Faculty Patents

A method of treating leukemia which includes administering an effective amount of composition comprising suramin and a biological response modifier, wherein the suramin and the biological response modifier show synergistic or additive anti-leukemic activity. A pharmaceutical composition is also disclosed.

Ada News - 09/18/2000, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Single Channel Properties And Regulated Expression Of Ca2+ Release-Activated Ca2+ (Crac) Channels In Human T Cells, Alla F. Fomina, Christopher M. Fanger, J. Ashot Kozak, Michael D. Cahalan

Neuroscience, Cell Biology & Physiology Faculty Publications

Although the crucial role of Ca²⁺ influx in lymphocyte activation has been well documented, little is known about the properties or expression levels of Ca²⁺ channels in normal human T lymphocytes. The use of Na⁺ as the permeant ion in divalent-free solution permitted Ca²⁺ release-activated Ca²⁺ (CRAC) channel activation, kinetic properties, and functional expression levels to be investigated with single channel resolution in resting and phytohemagglutinin (PHA)-activated human T cells. Passive Ca²⁺ store depletion resulted in the opening of 41-pS CRAC channels characterized by high open probabilities, voltage-dependent block by extracellular Ca²⁺ in …

Medicare+Choice: Where To From Here?, Nora Super

National Health Policy Forum

This issue brief examines Medicare+Choice (M+C) plan participation, benefit coverage, and enrollment and the factors that have contributed to plans' decisions to participate in or withdraw from certain markets. In addition, the issue brief explores what has been happening to M+C enrollees in terms of costs, benefits, and continuity of care. Lastly, the issue brief examines the reasons that alternative plan options — such as preferred provider organizations (PPOs) and provider-sponsored organizations (PSOs) — have not taken hold. Legislative proposals that might affect the future of M+C are also discussed.

Hsv Latency-Associated Transcript And Neuronal Apoptosis, Anthony B. Nesburn, Clinton J. Jones

School of Veterinary and Biomedical Sciences: Faculty Publications

Thompson and Sawtell report that the Promega Anti-PARP p85 antibody did not recognize cleaved PARP in mouse or rabbit cells in their experiments, and conclude that the results reported with this antibody by Perng et al. (1) are an artifact. The Promega antibody was generated against a peptide based on the sequence of human p85. Although the corresponding bovine sequence differs by two amino acids, the antibody reacts with both human and bovine p85 (2). The mouse and rat sequences for this region of p85 differ from the human sequence by a single amino acid that corresponds to one of …

Ada News - 09/04/2000, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Can Sports Survive The ‘Survivor’ Craze, Rick Burton

Sport Management - All Scholarship

No abstract provided.

Characteristics Of Nursing Doctoral Programs In The United States, Melanie Mcewen, Gregory A. Bechtel

Nursing Faculty Publications

The expansive growth of doctoral programs in the United States has necessitated a need to determine demographic attributes of the academic program, characteristics of the students, admission criteria, and curriculum patterns. Seventy-eight doctoral programs were sent a researcher-designed survey and 48 (62 per cent) responded. Results show an increasing shift away from clinical doctorates to the research doctorate, although few differences exist within the research focus of doctoral nursing programs. Consistent with previous reports in the literature, curricula are fairly standard and few differences were noted based on a number of criteria including geographic location, type of degree granted, Carnegie …

The Long Road Called Goodbye (Excerpt), Charlotte A. Akin

Biography

Part clinical case study, part family journal, The Long Road Called Goodbye is a powerful and moving account of one family's thirteen-year struggle with Alzheimer's. This engaging informative book is a closely documented clinical study that reads like a novel, filled with all the feelings, crises, and conflicts experienced by patient and family. It is a story of love, loyalty, perseverance, strength, and dignity. The Long Road Called Goodbye makes a major contribution to the care of AD patients and their families. The book will be of interest to professionals who work with Alzheimer's patients, including physicians, staff at care-giving …

Readiness For Health Promotion, Colleen Murphy-Southwick Ph.D., Tom Seekins Ph.D., University Of Montana Rural Institute Rural Institute

Health and Wellness

There is growing interest in health promotion, wellness, and the prevention of secondary conditions among people with disabilities. In rural areas where there is limited access to health care providers knowledgeable about disability, managing one’s own health and wellness and using strategies to prevent secondary conditions may be particularly important (Offner, Seekins & Clark, 1992; Seekins, 1992; Center for Disability Policy and Research, 1995; Seekins, Clay & Ravesloot, 1994; Seekins, et al., 1999).

Ouabain Interaction With Cardiac Na+/K+-Atpase Initiates Signal Cascades Independent Of Changes In Intracellular Na+ And Ca2+, Jiang Liu, Jiang Tian, Michael Haas, Joseph I. Shapiro, Amir Askari, Zijian Xie

Pharmaceutical Science and Research

We have shown previously that partial inhibition of the cardiac myocyte Na⁺/K⁺-ATPase activates signal pathways that regulate myocyte growth and growth-related genes and that increases in intracellular Ca²⁺ concentration ([Ca²⁺]i) and reactive oxygen species (ROS) are two essential second messengers within these pathways. The aim of this work was to explore the relation between [Ca²⁺]i and ROS. When myocytes were in a Ca²⁺-free medium, ouabain caused no change in [Ca²⁺]i, but it increased ROS as it did when the cells were in …

Community-Based Nursing Education At The Campsite, M. Susan Jones, Donna Bussey, Carrie Morgan

Nursing Faculty Publications

No abstract provided.

Helicobacter Pylori Serology And The Diagnosis Of H. Pylori Infection In Children, Yoram Elitsur, Rafah Aflak, Cheryl Neace, W. E. Triest

Biochemistry and Microbiology

Serological screening accuracy rate may be dependent on clinical and pathological determinants. The aim of this study was to evaluate the accuracy of Hp serology test (Roche Biomedical Lab., Labcorp), In the diagnosis of Hp infection in 121 children who were seen in the Pediatric Gastoenterology Clinic at the Marshall University Joan C. Edwards School of Medicine In Huntington. Positive serology detected children with Hpassociated gastritis with a sensitivity of 51.6%. Positive serology significantly correlated with the degree of gastric inflammation and density of Hp organisms in the gastric mucosa (ANOVA p < 0.001). The Labcorp. Hp-ELISA test had a poor accuracy rate for the detection of Hp-gastritis in children. Gastric biopsies should always be performed to establish the diagnosis of Hp infection in children.

Abdominal Fluid Collection After Laparoscopic Cholecystectomy, Vivian Mcalister

Data and Test Instruments

A middle aged man who complains of abdominal pain and bloat for 3 days after a combined laparoscopic cholecystectomy and umbilical hernia repair develops a fistula through the umbilical wound. How should care proceed? Vivian McAlister of Halifax, Nova Scotia replies.

The Asthma Epidemic: Prospects For Controlling An Escalating Public Health Crisis, Richard Hegner

National Health Policy Forum

This background paper examines the dimensions of the recent asthma epidemic and what could be done to contain it. Information about the prevalence and consequences of asthma across demographic groups is presented. Factors that impede the control of asthma are also identified. The paper also examines the possible causes of asthma and the asthma epidemic as well as new theories about the relationship of asthma to overall advances in health care and economic development. It also discusses the economic implications of asthma and possible cost avoidances linked to better asthma management. The paper concludes with discussions of asthma and public …

Low Serum Alpha 1 Antitrypsin In Duodenal Ulcer--A Family Study, Anjum Shahid, Sarwar J, Zuberi Mohammad A, Waqar,Huma Qureshi Waqar,Huma Qureshi Waqar,Huma Qureshi, Anwar Ali Siddiqui, Taranum Sultana

Department of Biological & Biomedical Sciences

No abstract provided.

Surgical Management Of Penile Cancer: Report Of Two Cases, M Amjad Noor, Muhammad Hammad Ather, M Nasir Sulaiman, Farhat Abbas

Section of Urology

No abstract provided.

Intestinal Lesions Caused By A Strain Of Chlamydia Suis In Weanling Pigs Infected At 21 Days Of Age, Douglas G. Rogers, Arthur A. Andersen

School of Veterinary and Biomedical Sciences: Faculty Publications

The objective of this study was to determine whether a strain of Chlamydia suis shown previously to be an intestinal pathogen in gnotobiotic piglets could cause diarrhea and intestinal lesions in young weanling pigs. Pigs from 2 sows were randomly assigned to 2 groups. Group 1 included 13 pigs that were weaned at 24 hours of age and then housed in isolator units and fed milk replacer and unmedicated starter ration. Group 2 included 8 pigs that nursed their respective sows, consumed unmedicated starter ration, and were weaned at 21 days of age. Ten pigs in group 1 and 6 …

Research To Practice: Self-Determination And Struggle In The Lives Of Adolescents, Mairead Moloney, Jean Whitney-Thomas, Danielle Dreilinger

Research to Practice Series, Institute for Community Inclusion

As students of all ability levels move into adulthood, they seek to define themselves and develop goals for the future. This study identifies four categories of students and offering targeted suggestions for support.

Contingencies Governing The Production Of Fricatives, Affricates, And Liquids In Babbling, Christina E. Gildersleeve-Neumann, Barbara L. Davis, Peter F. Macneilage

Speech and Hearing Sciences Faculty Publications and Presentations

Studies of early-developing consonants (stops, nasals, and glides) in babbling have shown that most of the variance in consonants and their associated vowels, both within and between syllables, is due to a "frame" produced by mandibular oscillation, with very little active contribution from intrasyllabic or intersyllabic tongue movements. In a study of four babbling infants, the prediction that this apparently basic "frame dominance" would also apply to late-developing consonants (fricatives, affricates, and liquids) was tested. With minor exceptions, confirming evidence for both the predicted intrasyllabic and intersyllabic patterns was obtained. Results provide further evidence for the frame dominance conception, but …