Medicine and Health Sciences Commons^™

Impulsivity And Smoking Relapse, Neal Doran, Bonnie Spring, Dennis E. Mcchargue, Michele Pergadia, Malia Richmond

Department of Psychology: Faculty Publications

Previous research has shown that elevated trait-impulsivity heightens the risk for initiating tobacco use and indicates that nicotine may be disproportionately rewarding for more impulsive persons. However, the influence of impulsivity on the ability to maintain nicotine abstinence has not been studied. The present study tested the hypothesis that a higher level of trait-impulsivity would predict a more rapid relapse to smoking following 48 hr of nicotine abstinence. Participants were euthymic, regular smokers (N=45), with a history of at least one major depressive episode, who participated in a paid smoking cessation study with biological challenge (tryptophan depletion). Treatment …

Inside Unlv, Cate Weeks, Carol C. Harter, Diane Russell, Holly Ivy De Vore

Inside UNLV

No abstract provided.

Hsp27 Anti-Sense Oligonucleotides Sensitize The Microtubular Cytoskeleton Of Chinese Hamster Ovary Cells Grown At Low Ph To 42 Degrees C-Induced Reorganization, Michael T. Hargis, C. W. Storck, Eric Wickstrom, Leonid A. Yakubov, Dennis B. Leeper, Ronald A. Coss

Department of Biochemistry and Molecular Biology Faculty Papers

Chinese hamster ovary (CHO) cells maintained in vitro at pH 6.7 were used to model cells in the acidic environment of tumours. CHO cells grown at pH 6.7 develop thermotolerance during 42 degrees C heating at pH 6.7 and their cytoskeletal systems are resistant to 42 degrees C-induced perinuclear collapse. Hsp27 levels are elevated in cells grown at pH 6.7 and are further induced during 42 degrees C heating, while Hsp70 levels remain low or undetectable, suggesting that Hsp27 is responsible for some of the novel characteristics of these cells. An anti-sense oligonucleotide strategy was used to test the importance …

Incidental Intrarenal-Pelvic Hydatid Cyst Discovered During Percutaneous Nephrolithotomy (Pcnl), G M. Nandwani, S R. Biyabani, A Memon

Section of Urology

No abstract provided.

Langerhans Cell Histiocytosis Of The Spine In Children: Long-Term Follow-Up, Sumeet Garg, Samir Mehta, John P. Dormans

Open Access Publications

No abstract provided.

Prevention And Management Of Iatrogenic Flatback Deformity, Benjamin K. Potter, Lawrence G. Lenke

Open Access Publications

No abstract provided.

New Drug: Prevacid I.V. (Lansoprazole) Injection, Joseph A. Woelfel

School of Pharmacy Faculty Articles

No abstract provided.

Proton Pump Inhibitors Associated With Increased Risk Of Clostridium Difficile Diarrhea, Joseph A. Woelfel

School of Pharmacy Faculty Articles

No abstract provided.

Frequency Of Hereditary Thrombophilia: An Akuh Experience., Safoorah Khalid, Raihan Sajid, Salman Adil, Mohammad Khurshid

Department of Pathology and Laboratory Medicine

Abstract

Objective: To determine the frequency of various causes of hereditary thrombophilia at a referral laboratory and the age and gender distribution.

Methods: This is a descriptive study incorporating a retrospective analysis of requests for thrombophilia screening sent to Clinical laboratory, Aga Khan University Hospital from November 1995 to May 2002.
Patients were screened for hereditary causes of thrombophilia including Protein C, Protein S, antithrombin III, Factor V Leiden and homocysteine. Frequency of each disorder; and age and sex distribution was determined.

Results: All the patients suspected clinically for thrombophilia were screened. Of the 2825 patients, 70 were diagnosed to …

Animal Health Laboratories Service Manual 2004-2005, Department Of Agriculture And Food, Western Australia

Agriculture reports

This service manual is designed to help you, the user of services provided by the Animal Health Laboratories (AHL), to get the most from the laboratories. If you have questions on any matters relating to the AHL services or sample collection, please telephone us. If you need to contact someone regarding AHL services or are unsure of which samples to collect, contact staff at AHL by consulting the directory of key personnel. The section on ‘General Instructions’ contains information required for packaging and submission of samples to AHL. Other sections contain information on the type of sample required for each …

The Major Subunit Of The Toxin-Coregulated Pilus Tcpa Induces Mucosal And Systemic Immunoglobulin A Immune Responses In Patients With Cholera Caused By Vibrio Cholerae O1 And O139, Muhammad Asaduzzaman, Edward T. Ryan, Manohar John, Long Hang, Ashraful I. Khan, A. S. G. Faruque, Ronald K. Taylor

Dartmouth Scholarship

Diarrhea caused by Vibrio cholerae is known to give long-lasting protection against subsequent life-threatening illness. The serum vibriocidal antibody response has been well studied and has been shown to correlate with protection. However, this systemic antibody response may be a surrogate marker for mucosal immune responses to key colonization factors of this organism, such as the toxin-coregulated pilus (TCP) and other factors. Information regarding immune responses to TCP, particularly mucosal immune responses, is lacking, particularly for patients infected with the El Tor biotype of V. cholerae O1 or V. cholerae O139 since highly purified TcpA from these strains has not …

Psychometric Testing Of The Self-Care Of Heart Failure Index, Barbara Riegel, Beverly Carlson, Debra K. Moser, Margaret Sebern, Frank D. Hicks, Virginia Roland

College of Nursing Faculty Research and Publications

Background: Self-care is believed to improve outcomes in heart failure (HF) patients. However, research testing this assumption is hampered by difficulties in measuring self-care. The purpose of this study was to evaluate the psychometric properties of a revised instrument measuring self-care in persons with HF, the Self-Care of Heart Failure Index (SCHFI). The SCHFI is a self-report measure comprised of 15 items rated on a 4-point response scale and divided into 3 subscales.

Methods and Results: Psychometric testing was done using data from 760 HF patients (age 70.36 ± 12.3 years, 51% male) from 7 sites in the United States. …

Collaborative Management Of Hiv Infection In The Community: An Effort To Improve The Quality Of Hiv Care, Michael F. Parry, Julie G. Stewart, P. Wright, Gavin X. Mcleod

Nursing Faculty Publications

Our hospital led a multidisciplinary community team to improve the quality of care delivered to HIV-infected clients utilizing a disease management approach in a US metropolitan community of 150,000 people. Community needs assessment and client and community surveys were used to define the problems. Patient care flowcharting and the creation of an electronic patient database facilitated patient tracking across the entire community. Clinical guidelines and a consultation and referral immunology clinic standardized care practices. Measurable improvements in the quality of care were noted in multiple areas. Flowchart completion rates rose from 44% to 100%; medication adherence assessment rose from 82% …

Clarithromycin Induced Digoxin Toxicity: Case Report And Review, N Kiran, S Azam, S Dhakam

Section of Cardiology

No abstract provided.

Letter To The Editor: Response To Covey, Brian Hitsman, Bonnie Spring, Belinda Borrelli, Dennis E. Mcchargue, Raymond Niaura

Department of Psychology: Faculty Publications

Dr. Covey asserts that our meta-analysis of the association between history of major depression and smoking treatment outcome (Hitsman, Borrelli, McChargue, Spring, & Niaura, 2003) was flawed because we did not limit our analysis to participants randomized to placebo or alternative least intensive treatment condition.

Cutaneous Manifestations Of Hyper-Ige Syndrome In Twins: A Case Report From Saudi Arabia., Azam J. Samdani, A. Tania

Department of Medicine

The hyper-IgE syndrome with recurrent infections is a rare immunodeficiency disorder characterized by very high levels of IgE in serum. It is inherited in most of the cases in a dominant fashion meaning that it can run in families with a high frequency. About 250 cases have been published in literature so far.

The Promise And The Reality Of Long-Term Care Insurance, Randy Desonia

National Health Policy Forum

The aging of the nation’s population will create a surge in the need for long-term care services, putting pressure on existing funding sources and fueling demand for more. This paper examines one financing option—private long-term care insurance—and summarizes its brief history and the several critical precedents that have influenced the products as currently sold. Other topics discussed include the challenges to encouraging sales growth as well as increasing the role of this type of insurance in paying for long-term care.

Non-Parametric Estimation Of Roc Curves In The Absence Of A Gold Standard, Xiao-Hua Zhou, Pete Castelluccio, Chuan Zhou

UW Biostatistics Working Paper Series

In evaluation of diagnostic accuracy of tests, a gold standard on the disease status is required. However, in many complex diseases, it is impossible or unethical to obtain such the gold standard. If an imperfect standard is used as if it were a gold standard, the estimated accuracy of the tests would be biased. This type of bias is called imperfect gold standard bias. In this paper we develop a maximum likelihood (ML) method for estimating ROC curves and their areas of ordinal-scale tests in the absence of a gold standard. Our simulation study shows the proposed estimates for the …

Research News: 2004, No. 2, University Of Mississippi. School Of Pharmacy

Research News: Grants and Publications (2000-2014)

Grants, publications, technology transfer, special announcements

Biochemical Enrichment And Biophysical Characterization Of A Taste Receptor For L-Arginine From The Catfish, Ictalurus Puntatus., William Grosvenor, Yuri Kaulin, Andrew I Spielman, Douglas L Bayley, D Lynn Kalinoski, John H Teeter, Joseph G Brand

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

BACKGROUND: The channel catfish, Ictalurus punctatus, is invested with a high density of cutaneous taste receptors, particularly on the barbel appendages. Many of these receptors are sensitive to selected amino acids, one of these being a receptor for L-arginine (L-Arg). Previous neurophysiological and biophysical studies suggested that this taste receptor is coupled directly to a cation channel and behaves as a ligand-gated ion channel receptor (LGICR). Earlier studies demonstrated that two lectins, Ricinus communis agglutinin I (RCA-I) and Phaseolus vulgaris Erythroagglutinin (PHA-E), inhibited the binding of L-Arg to its presumed receptor sites, and that PHA-E inhibited the L-Arg-stimulated ion conductance …

Salmonella In Songbirds

Zoonotics and Wildlife Disease: Publications

Salmonella is a type of bacterium found in the gut of many species of birds both domestic and wild. During periods of stress it can cause outbreaks of sickness and death. Its importance in songbird populations generally and the occurrence of outbreaks in this province specifically are discussed in this fact sheet.

Parasites Of Caribou (1): Brain Worm Infestation

Zoonotics and Wildlife Disease: Publications

Brain worm is the common name for a disease of caribou that was first recognized in Central Newfoundland in the 1970's and has since been seen in other caribou herds including most recently the caribou of the Southern Avalon. Its more scientific name is Cerebrospinal Elaphostrongylosis (CSE) and is caused by the nematode Elaphostrongylus rangiferi.
Infection can cause severe illness and death in affected animals and has a particularly strong impact on herds that have not been previously exposed to this parasite.
As this is primarily a disease of caribou, there is no direct public health threat to humans. Moose …

Parasites Of Caribou (2): Fly Larvae Infestations

Zoonotics and Wildlife Disease: Publications

All wild animals carry diseases. In some cases these might be of concern if they can spread to humans or domestic animals. In other cases they might be of interest if they impact on the health of our wild herds, or simply because the signs of the disease have been noticed and you want to know more.
This fact sheet is one of a series produced on the common diseases of caribou and covers the larval form of two different flies commonly seen in this province. Neither of these are a cause of public health concern.

Parasites Of Caribou (3): Tapeworm Cysts

Zoonotics and Wildlife Disease: Publications

All wild animals carry diseases. In some cases these might be of concern if they can spread to humans or domestic animals. In other cases, they might be of interest if they impact on the health of our wild herds, or simply if they have been noticed by hunters and you would like to know more.
This fact sheet is one of a series produced on the common diseases of caribou and covers the cyst form of three common tapeworms. Two (Taenia hydatigena and Taenia krabbei) exist on both the island of Newfoundland and in Labrador, while the …

Pesticide Poisoning Of Seagulls

Zoonotics and Wildlife Disease: Publications

In April 2000 a major pesticide leak caused the death and illness of a significant number of wild birds. The findings and conclusions of this die-off are detailed.

Parasites Of The Snowshoe Hare (1): Tapeworm Cysts

Zoonotics and Wildlife Disease: Publications

All wild animals carry diseases. In some cases these might be of concern because they can spread to humans or domestic animals. In other cases they may be of interest simply because the signs of the disease have been seen and you want to know more. Though diseases are relatively common in these animals there is usually an increase in reporting when the hare populations are at a peak. High populations mean that there is an increased chance of one animal infecting another. In addition, when there are too many animals in one area, the amount of available food is …

Agribusiness Sheep Updates - 2004 Part 2, Anyou Liu, Clinton Revell, Phil Nichols, Brad Nutt, Darryl Clements, Lucy Anderton, Stephen Gherardi, Chris Oldham, Paul Sanford, John Gladman, G. E. Donald, A. Edirisinghe, D. A. Henry, S. P. Gittins, R. C. G. Smith, Roy Butler, Kelly Pearce, David Masters, David Pethick, Andrew Thompson, Ken Hart, Johan Greeff, Beth Paganoni, Rachel Kirby, Matt Ryan, Kira Butler, Roger Heggarty, David Hopkins, Samantha Giles, Tom Plaisted, Mark Ferguson, Darren Gordon, John Young, Sandra Brown, Ian Mcfarland, John Archer, John Milton, Rob Davidson, Graeme Martin, David Lindsay, Johnathan England, Mandy Curnow, Karina P. Wood, Ashley K. White, B. Lloyd Davies, Paul M. Carberry, Mark Hyder, Mike Freer, Andrew Van Burgel, Kazue Tanaka, Andrew Peterson, Roger Wiese, Gonzalo Mata, Evan Burt, Amanda Miller, Anne Bennett, Felicity Flugge, Amir Abadi, Perry Dolling, Dean Thomas, Mike Ewing, David Lindsay, Emma Kopke, E. A. Dowling, E. K. Crossley, Brien (Ben) E. Norton, John Karlsson, Geoff Pollott, Diana Fedorenko, Darryl Clements, Robert Beard, Brown Besier, Una Ryan, Caroline Bath

Sheep Updates

Precision Pastures

Using Species Diversity to Improve Pasture Performance Anyou Liu and Clinton Revell, Department of Agriculture, Western Australia

New Annual Pasture Legumes for Sheep Graziers Phil Nichols, Angelo Loi, Brad Nutt and Darryl McClements Department of Agriculture Western Australia

Pastures from Space – Can Satellite Estimates of Pasture Growth Rate be used to Increase Farm Profit? Lucy Anderton, Stephen Gherardi and Chris Oldham Department of Agriculture Western Australia

Summer-active Perennial Grasses for Profitable Sheep Production Paul Sanford and John Gladman, Department of Agriculture, Western Australia

Pastures From Space – Validation Of Predictions Of Pasture Growth Rates DONALD, G.E^{.A …}

Agribusiness Sheep Updates - 2004 - Part 1, Mark Dolling, Len Stephens, David Thomanson, Norm Adams, Shimim Liu, Peter Buchman, Mike Paton, Dianne Evans, John Edwards, Scott Champion, Alan Langford, A. C. Schlink, J. C. Greeff, M. E. Ladyman, Kimbal M. S. Curtis, John Stanton, Stuart Adams, Neal Fogarty, Matthew Kelly, James Skerritt, Ian Mcfarland

Sheep Updates

Proceedings of the Agribusiness Sheep Updates - 2004 Forward Dr Mark Dolling Manager, Sheep Industries and Pasture, Department of Agriculture Western Australia Keynotes Australian Wool Innovation Limited DR LEN STEPHENS AUSTRALIAN WOOL INNOVATION LIMITED (AWI) Commercialisation of Sheepmeat Eating Quality Outcomes, David Thomason, General Manger Marketing Meat & livestock Australia Limited PLENARY The Fitness of the Future Merino, Norm Adams and Shimin Liu, CSIRO Livestock Industries Ovine Johne’s Disease – Managing the Disease, Managing the Issues, PETER BUCKMAN, CHIEF VETERINARY OFFICER, DEPARTMENT OF AGRICULTURE WESTERN AUSTRALIA Animal Welfare – Changes in Latitudes Changes in Attitudes, Michael Paton and Dianne Evans, …

Keep Your Cabin Free Of Rodents

Zoonotics and Wildlife Disease: Publications

Cabins that have been closed for the winter can become nesting sites for mice, shrews and other rodents. These animals can carry fleas, ticks, viruses or other organisms on their skin, in their droppings or urine. These can cause diseases in humans, especially when you breathe in the dust from their droppings or nesting sites.
Avoid close contact with rodent urine, droppings, nesting materials or with any food or surfaces contaminated with them.
Always wear rubber gloves when handling dead rodents, or when cleaning traps, droppings, nesting sites or other areas that rodents may have visited.

Permeable, Water Soluble, Non-Irritating Prodrugs Of Chemotherapeutic Agents With Oxaalkanoic Acids, Peter A. Crooks, Tadeusz Cynkowski, Grazyna Cynkowska, Hong Guo, Paul Ashton

Pharmaceutical Sciences Faculty Patents

The present invention relates to the field of prodrugs of chemotherapeutic agents and method of use thereof.