Medicine and Health Sciences Commons^™

Robust Acoustic Trapping And Perturbation Of Single-Cell Microswimmers Illuminate Three-Dimensional Swimming And Ciliary Coordination, Mingyang Cui, Susan K Dutcher, Philip V Bayly, J Mark Meacham

2020-Current year OA Pubs

We report a label-free acoustic microfluidic method to confine single, cilia-driven swimming cells in space without limiting their rotational degrees of freedom. Our platform integrates a surface acoustic wave (SAW) actuator and bulk acoustic wave (BAW) trapping array to enable multiplexed analysis with high spatial resolution and trapping forces that are strong enough to hold individual microswimmers. The hybrid BAW/SAW acoustic tweezers employ high-efficiency mode conversion to achieve submicron image resolution while compensating for parasitic system losses to immersion oil in contact with the microfluidic chip. We use the platform to quantify cilia and cell body motion for wildtype biciliate …

Lateral Line Ablation By Ototoxic Compounds Results In Distinct Rheotaxis Profiles In Larval Zebrafish, Kyle C Newton, Dovi Kacev, Simon R O Nilsson, Allison L Saettele, Sam A Golden, Lavinia Sheets

2020-Current year OA Pubs

The zebrafish lateral line is an established model for hair cell organ damage, yet few studies link mechanistic disruptions to changes in biologically relevant behavior. We used larval zebrafish to determine how damage via ototoxic compounds impact rheotaxis. Larvae were treated with CuSO

University Of Maine Athletics_Heathcare Worker Thank You_Justin Alley, University Of Maine Athletics

Athletics Department

Thank you to University of Maine Alumnus and healthcare worker Justin Alley. Alley was a member of the Class of 2006 and a swimmer at the University of Maine. The thank you's were sent out by University of Maine Athletics during the COVID-19 pandemic.

University Of Maine Athletics_Heathcare Worker Thank You_Lilli Wiseman, University Of Maine Athletics

Athletics Department

Thank you to University of Maine Alumna and healthcare worker Lilli Wiseman. Wiseman was a member of the Class of 2017 and a swimmer at the University of Maine. The thank you's were sent out by University of Maine Athletics during the COVID-19 pandemic.

App21 Transgenic Rats Develop Age-Dependent Cognitive Impairment And Microglia Accumulation Within White Matter Tracts., Nina Weishaupt, Qingfan Liu, Sheojung Shin, Ramandeep Singh, Yuksel Agca, Cansu Agca, Vladimir Hachinski, Shawn Narain Whitehead

Paediatrics Publications

Background

Most of the animal models commonly used for preclinical research into Alzheimer's disease (AD) largely fail to address the pathophysiology, including the impact of known risk factors, of the widely diagnosed sporadic form of the disease. Here, we use a transgenic rat (APP21) that does not develop AD-like pathology spontaneously with age, but does develop pathology following vascular stress. To further the potential of this novel rat model as a much-needed pre-clinical animal model of sporadic AD, we characterize APP21 transgenic rats behaviorally and histologically up to 19 months of age.

Methods

The open field test was used as …

Predictors Of Swimming Ability Among Children And Adolescents In The United States, Jennifer Pharr, Carol Irwin, Todd Layne, Richard Irwin

Public Health Faculty Publications

Swimming is an important source of physical activity and a life skill to prevent drowning. However, little research has been conducted to understand predictors of swimming ability. The purpose of this study was to understand factors that predict swimming ability among children and adolescents in the United States (US). This was a cross-sectional survey conducted between February and April of 2017 across five geographically diverse cities. Participants were accessed through the Young Christian Men’s Association (YMCA) and included parents of children aged 4–11 years old and adolescents aged 12–17 years old. Independent t-test, analysis of variance (ANOVA), and univariate and …

College Of Public Health News, Georgia Southern University

Jiann-Ping Hsu College of Public Health News (2011-2023)

• Georgia Southern Conducts a Preliminary Examination of Blood Leave Levels in Rural Georgia
• Georgia Southern Examines Informatics as a Strategic Priority
• Georgia Southern Partners to Assess Risk Factors for Public Swimming Pools

Performance Profiles Of Collegiate And Master’S Swimmers: A Validation Study, Lyle E. Robelot Mr.

Faculty Publications

The purpose of this proposal is to link the gold standard power test on land (Wingate test) to an in-water power test. There is a lack of information on power in the water and would be beneficial in tracking swimmers progress throughout a season and between seasons. Power curves of individuals on the Wingate test will be compared to those of In-water tests to see weather this water test is valid. The experiment will follow IRB rules and regulation and the staff will adhere to the safety conditions set forth by the IRB.

Parental Factors That Influence Swimming In Children And Adolescents, Jennifer Pharr, Carol C. Irwin, Richard L. Irwin

Environmental & Occupational Health Faculty Publications

Swimming can be an important source of physical activity across the life-span. Researchers have found that parents influence physical activity behaviors of their children. The purpose of this study was to determine what parental factors influenced the number of days that children swam. Survey respondents (n = 1,909) from six cities across the United States were surveyed at local YMCAs. Children were found to swim significantly more if their parents encouraged them to swim, members of the family knew how to swim and swam with them, or their parents were not afraid of the children drowning or afraid of …

Effects Of Standard Labor-Wear On Swimming And Treading Water, John Amtmann, Edd, Les Harris, William K. Spath, Charles Todd, Phd

Applied Health Sciences

We tested the hypothesis that occupational clothing would impair performance during swimming. The sub questions included: (1) Will the standard work wear of a railway worker or laborer impede swimming ability? (2) Will this clothing impact the individual’s ability to tread water? We addressed the research questions with three hypotheses. Analysis showed statistically significant p-values and all three null hypotheses were rejected in favor of the three research hypotheses, showing strong evidence that standard labor wear had adverse effects on 11.43 meter/12.5 yard swim time, water treading time and rate of perceived exertion (RPE) during water treading. The mean swim …

Paradoxical Reversal Learning Enhancement By Stress Or Prefrontal Cortical Damage: Rescue With Bdnf., Carolyn Graybeal, Michael Feyder, Emily Schulman, Lisa M Saksida, Timothy J Bussey, Jonathan L Brigman, Andrew Holmes

Brain and Mind Institute Researchers' Publications

Stress affects various forms of cognition. We found that moderate stress enhanced late reversal learning in a mouse touchscreen-based choice task. Ventromedial prefrontal cortex (vmPFC) lesions mimicked the effect of stress, whereas orbitofrontal and dorsolateral striatal lesions impaired reversal. Stress facilitation of reversal was prevented by BDNF infusion into the vmPFC. These findings suggest a mechanism by which stress-induced vmPFC dysfunction disinhibits learning by alternate (for example, striatal) systems.

A Community Outbreak Of Cryptosporidiosis In Sydney Associated With A Public Swimming Facility: A Case-Control Study, Darren J. Mayne, Kelly-Anne Ressler, Diane Smith, Gareth Hockey, Susan J. Botham, Mark J. Ferson

Illawarra Health and Medical Research Institute

In February, 2008, the South Eastern Sydney Illawarra Public Health Unit investigated an outbreak of cryptosporidiosis within the south east region of Sydney, Australia. Thirty-one cases with laboratory-confirmed cryptosporidiosis and 97 age- and geographically matched controls selected by random digit dialling were recruited into a case-control study and interviewed for infection risk factors. Cryptosporidiosis was associated with swimming at Facility A (matched odds ratio = 19.4, 95% confidence interval: 3.7-100.8) and exposure to household contacts with diarrhoea (matched odds ratio = 7.7, 95% confidence interval: 1.9-31.4) in multivariable conditional logistic regression models. A protective effect for any animal contact was …

Pseudomonas Aeruginosa Evasion Of Phagocytosis Is Mediated By Loss Of Swimming Motility And Is Independent Of Flagellum Expression, Eyal Amiel, Rustin R. Lovewell, George A. O'Toole, Deborah A. Hogan, Brent Berwin

Dartmouth Scholarship

Pseudomonas aeruginosa is a pathogenic Gram-negative bacterium that causes severe opportunistic infections in immunocompromised individuals; in particular, severity of infection with P. aeruginosa positively correlates with poor prognosis in cystic fibrosis (CF) patients. Establishment of chronic infection by this pathogen is associated with downregulation of flagellar expression and of other genes that regulate P. aeruginosa motility. The current paradigm is that loss of flagellar expression enables immune evasion by the bacteria due to loss of engagement by phagocytic receptors that recognize flagellar components and loss of immune activation through flagellin-mediated Toll-like receptor (TLR) signaling. In this work, we employ bacterial …

Surveillance For Waterborne-Disease Outbreaks Associated With Recreational Water--United States, 2001-2002, Jonathan S. Yoder, Brian G. Blackburn, Gunther F. Craun, Vincent Hill, Deborah A. Levy, Nora Chen, Sherline H. Lee, Rebecca L. Calderon, Michael J. Beach

Journal Articles: Epidemiology

PROBLEM/CONDITION: Since 1971, CDC, the U.S. Environmental Protection Agency, and the Council of State and Territorial Epidemiologists have maintained a collaborative surveillance system for collecting and periodically reporting data related to occurrences and causes of waterborne-disease outbreaks (WBDOs) related to drinking water; tabulation of recreational water-associated outbreaks was added to the surveillance system in 1978. This surveillance system is the primary source of data concerning the scope and effects of waterborne disease outbreaks on persons in the United States.

REPORTING PERIOD COVERED: This summary includes data on WBDOs associated with recreational water that occurred during January 2001-December 2002 and on …

Isbs '99 : Xvii International Symposium On Biomechanics In Sports, June 30-July 6, 1999, Edith Cowan University, Perth, Western Australia: Swimming, Ross Sanders (Ed.)

Research outputs pre 2011

No abstract provided.

Fornix Lesions Can Facilitate Acquisition Of The Transverse Patterning Task: A Challenge For "Configural" Theories Of Hippocampal Function., T J Bussey, E Clea Warburton, J P Aggleton, J L Muir

Brain and Mind Institute Researchers' Publications

Configural theories of hippocampal function predict that hippocampal dysfunction should impair acquisition of the transverse patterning task, which involves the concurrent solution of three discrimination problems: A+ versus B-; B+ versus C-; and C+ versus A-. The present study tested this prediction in rats using computer-graphic stimuli presented on a touchscreen. Experiment 1 assessed the effects of fornix lesions when the three problems were introduced sequentially (phase 1: A+ vs B-; phase 2: A+ vs B-, B+ vs C-; phase 3: A+ vs B-, B+ vs C-, C+ vs A-). Fornix lesions significantly facilitated acquisition of the complete transverse patterning …

Ariel - Volume 9 Number 4, Guy Giordano, Ed Silverman, Rob Kester, George Coar, Richard Yelovich, Brad Feldstein, Cathy Hayward, Steve Levine, Arthur Allen, W.D.B. Hiller, John P. Welch, James Weidman, John D. Angstadt, Elizabeth Mcguire, Eli Saleeby, Joel Shaffer

Ariel

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Ariel - Volume 9 Number 1, Lee Wugofski, Pat Welch, Steve Robb, Greg Slick, George Winch, Bert Schlowitz, Brad Feldstein, George Coar, Rick Bartlett, Steve Levine, Marilyn J. Mchenry, Douglas E. King, Rhonda Karp, Dan Flynn, Emily Wofford, Stu Gordon, Ed Little, Ray Mclaughlin

Ariel

Executive Editor

Emily Wofford

Business Manager

Fredric Jay Matlin

University News

John Patrick Welch

World News

George Robert Coar

Editorial Editor

Steve Levine

Feature

Brad Feldstein

Mark Rubin

Graphics

Steve Hulkower

Photo

Rick Spaide

Circulation

Lee Wugofski

Ariel - Volume 6 Number 3, Hans Weltin, J.D. Kanofsky, Ken Jaffe, Robert B. Baker, Robert L. Brent, Halley S. Faust, Jim Burke, Susan Shapiro, Gary Emmett, Curt Cummings

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Ariel - Volume 4 Number 6, Rockey Weber, Forrest West, Arnold J. Willis, Bob Sklaroff, Eugenia Miller, Joe Sassani, Laird G. Jackson, Joseph R. Berger, Albert L. Blumberg, J. S. Agnello, Jr., Thomas J.A. Lehman, Philip C. Hoffman, Robert Breckenridge, Jr., Gregory J. Edinger

Ariel

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