Medicine and Health Sciences Commons^™

Cortisol Production In Female Soccer Players, Katelyn Seagraves

ASPIRE 2024

Cortisol is released from the adrenal glands when there is an apparent stressor. Exercise, while beneficial, is seen as stress to the body and incites increased cortisol release. Cortisol is known to increase with exercise, and higher-intensity exercise tends to raise cortisol more compared to lower intensities. However, less is known about interval training and cortisol concentrations.

This review of literature dives into the background of cortisol: how it's produced, what systems it regulates, and differences in production based on gender, stressors, exercise intensity, and duration. This paper identifies some knowledge gaps and links training intensities in soccer to cortisol …

A Pilot Project To Improve The Well-Being Of Inpatient Nurse Managers At An Academic Medical Center Through A Mindfulness-Based Intervention, Nancy Wiederhold

Doctor of Nursing Practice Projects

Purpose: To decrease inpatient nurse managers' burnout, stress, and compassion fatigue through attendance at a mindful, self-compassion intensive program.

Background/Significance: Nurse leaders and managers are indispensable pillars of the healthcare team, carrying the responsibility of shaping organizational success and ensuring quality patient care. Unfortunately, the current landscape of nursing leadership is clouded by sentiments of powerlessness, hopelessness, and guilt.

Description: Recognizing the practical challenges faced by nurse managers, a targeted intervention was implemented – a four-week, in-person mindfulness-based, self-compassion program. This initiative aimed to equip them with the tools to mitigate stress, burnout, and compassion fatigue. Led by a trained …

Cortisol Production In Female Soccer Players, Katelyn Seagraves

Honors Projects

Cortisol is released from the adrenal glands when there is an apparent stressor. Exercise, while beneficial, is seen as stress to the body and incites increased cortisol release. Cortisol is known to increase with exercise, and higher-intensity exercise tends to raise cortisol more compared to lower intensities. However, less is known about interval training and cortisol concentrations.

This review of literature dives into the background of cortisol: how it's produced, what systems it regulates, and differences in production based on gender, stressors, exercise intensity, and duration. This paper identifies some knowledge gaps and links training intensities in soccer to cortisol …

Temporal Considerations In Brain Metastases Radiation Therapy: The Intersection Of Chronobiology And Patient Profiles, Nicolas Nelson, Sara Burke, Louis Cappelli, Lauren Matlack, Alexandria Smith, Noelle Francois, Joseph Lombardo, Yash Shah, Kuang-Yi Wen, Ayesha A Shafi, Nicole Simone

Department of Radiation Oncology Faculty Papers

The circadian system, a vital temporal regulator influencing physiological processes, has implications for cancer development and treatment response. Our study assessed circadian timing’s impact on whole-brain radiotherapy outcomes in brain metastases for personalized cancer therapy insights. The aim of the study was to evaluate circadian influence on radiation treatment timing and its correlation with clinical outcomes and to identify patient populations benefiting from interventions synchronizing circadian rhythms, considering subgroup differences and potential disparities. An IRB-approved retrospective analysis of 237 patients undergoing whole-brain radiotherapy for brain metastases (2017–2021), receiving over 80% of treatments in the morning or afternoon, was performed. Survival …

Modifying Aha Stress Management And Physical Activity Modules For Senior Communities, Madai Molina Apolinar, Kristina Luu, Sarah Allen, Samantha Isabel Pio Argueta, Annalise P. Sanders, Emil Visaya

Nursing Leadership in Community Engagement Projects

Modifying AHA Stress Management and Physical Activity Modules for Senior Communities

This quarter our group was given the opportunity to partner with two organizations to conduct work surrounding blood pressure and heart health education. One of our partners was a senior living organization whose mission is to transform beliefs about affordable housing through supporting communities where seniors and families can thrive. We also collaborated with the American Heart Association (AHA), which seeks to combat cardiovascular disease and stroke for the improvement and overall health of the population.

For this project, we were tasked with simplifying the AHA “Check. Change. Control.” …

Efficacy Of Hypnosis As A Treatment For Alopecia, Haya Beydoun, Meena Moossavi

Medical Student Research Symposium

Title:

Efficacy of Hypnosis as a treatment for Alopecia

Introduction:

Hypnosis is an altered state of consciousness in which someone is more receptive to suggestions and modeling, and it can address psychological and physical symptoms that are aggravated by conscious and unconscious triggers.The intended outcome is a change in certain behaviors or patterns of thinking that patients have which can mitigate their stress load. Stress can induce and exacerbate alopecia, and patients often suffer increased stress due to the psychosocial burden of having a dermatological disease. A study showed that high levels of cortisol releasing hormones (CRH) were found to …

Navigating New Normals: Student Perceptions, Experiences, And Mental Health Service Utilization In Post-Pandemic Academia, Hadiza Galadima, Anne Dumadag, Cara Tonn

Community & Environmental Health Faculty Publications

This study explores the profound impacts of the COVID-19 pandemic on higher education, focusing on shifts in learning experiences and students’ intentions to utilize mental health services post-pandemic. Utilizing Andersen’s Behavioral Model of Health Services Use, this study assesses perceptions from a stratified random sample of college students on post-pandemic learning experiences and mental health service utilization intentions. Findings reveal a positive reception to university initiatives and a preference for ongoing virtual classes. There is an evident increase in, and varying intentions for, using mental health services, shaped by demographics, employment, and prior service utilization. Younger and female students showed …

The Function Of Ask1 In Sepsis And Stress-Induced Disorders, John Kostyak, Steven Mckenzie, Ulhas Naik

Cardeza Foundation for Hematologic Research

Apoptosis signal-regulating kinase 1 (ASK1) is a serine-threonine kinase that is ubiquitously expressed in nucleated cells and is responsible for the activation of multiple mitogen-activated protein kinases (MAPK) to regulate cell stress. Activation of ASK1 via cellular stress leads to activation of downstream signaling components, activation of transcription factors, and proinflammatory cytokine production. ASK1 is also expressed in anucleate platelets and is a key player in platelet activation as it is important for signaling. Interestingly, the mechanism of ASK1 activation is cell type-dependent. In this review we will explore how ASK1 regulates a variety of cellular processes from innate immune …

Using Mindfulness In Nursing Burnout. An Integrative Review., April Day Branham

Doctoral Dissertations and Projects

The purpose of this integrative review is to evaluate if mindfulness is effective in decreasing nursing burnout. Nursing burnout has negatively affected the nursing profession for many years, and since the COVID-19 pandemic, it appears to be worse. Mindfulness is a practice that has been used for decades, however, it is gaining more attention in the nursing realm. Mindfulness consists of being present in a moment without judgment. It can consist of individual exercises that are completed using an instructor in person, in an application on a smartphone or computer, or yoga-based mindful activities. A preliminary literature review was completed …

Pre-Shift Mindfulness: An Evidence Based Practice Benchmark Project, Whitney Turner

MSN Capstone Projects

Although a nursing shortage has existed for some time, it seems there is currently a flight of both experienced and young clinicians from the bedside. Over the course of the Covid-19 pandemic, healthcare organizations have seen dramatic increases in turnover and vacancy rates, leading to severe staffing shortages and compromised patient care. Historically, nursing has been a caring, service driven profession, and a calling for millions of professionals. However, nurses are increasingly concerned with their personal wellbeing.

The term “burnout” appeared in the 1970s to describe the consequences of severe stress in “caring” professions, and include symptoms such as exhaustion, …

Editorial: Perspectives On Music And Pain: From Evidence To Theory And Application, Annabel J. Cohen, Andrea Mcgraw Hunt, Eduardo A. Garza-Villarreal, Xuejing Lu

College of Performing Arts Faculty Scholarship

No abstract provided.

Coping Strategies To Promote Mental Wellness, Luma Aziz, Domonique Jackson, Jessica Herzog, Molly Mcdonough, Ashley Kim, Arianne Faye Villaflor

Nursing Leadership in Community Engagement Projects

Coping Strategies to Promote Mental Wellness

Over eight weeks, our nursing school leadership team collaborated with a Seattle non- profit agency whose mission is to provide resources, planning, and housing to families with children experiencing homelessness. Our team’s overarching goal by the end of this project, based on the needs expressed by the agency, was to create a tool that provides resources and coping skills to families experiencing homelessness to improve mental health and promote wellness.

Background

The population that is served by the agency includes families with at least one child under the age of eighteen, children with medical …

Implementing Health Information Stations At Addiction Recovery Center, Esther Yi, Daryn Hernandez, Maryam Umer, Jasmine Alvarez, Kaitlyn Ward, Riciajoy Padilla

Nursing Leadership in Community Engagement Projects

Implementing Health Information Stations at the Addiction Recovery Center

Six Seattle Pacific University nursing students partnered with an addiction recovery center to address aging healthcare concerns. The recovery center is a non-profit organization that provides a refuge for healing for community members recovering from trauma, homelessness, addiction, and other mental health challenges. Through our weekly meetings with the community, we wanted to address specific barriers such as aging healthcare concerns. We focused on how the low-income aging population posed barriers to aging well.

Background

There has also been a rise in poverty in aging populations (Saldanha, 2023). Though aging influences …

Dispensing With Reductionism And Dualism: Biological Anthropological Perspectives Towards Understanding Disease, Epidemics, And Pandemics, Anne Grauer

Anthropology: Faculty Publications and Other Works

At no time in recent history has the topic of disease, epidemics and pandemics been more at the forefront of public conversation than it is now. Previously, the threat of epidemics such as Ebola, the 1918 influenza epidemic, and the plague, were commonly framed as “back then” or “over there.” Perhaps COVID ended the public's delusion. For biological anthropologists, however, the perspective has differed appreciably. Pandemics and epidemics are viewed as integral and repeated aspects of human existence, and the kindling to start an outbreak of gargantuan proportion has been delicately stacked for centuries (if not millennia). If the public …

Life Balance, Stress, And Occupational Burnout In Occupational Therapy Assistant Students: An Exploratory Study, Olivia W. Hammond, Mba, Otr/L, Cht

Post-Professional Occupational Therapy Doctorate Culminating Presentations

The United States healthcare worker burnout crisis demands immediate attention. College is critical for preparing occupational therapy assistant students (OTA) to address life balance, stress, and burnout as they transition into the workforce. However, little is known about these factors in this population. In this doctoral presentation, the primary author presents her doctoral project, which explored OTA students' life balance and its association with their perceived stress and occupational burnout across employment status, residential status, years of study, and age. A cross-sectional Qualtrics e-survey was distributed to OTA students ages 18 and older, including a demographic survey, Life Balance Inventory …

Burnout And Its Impact On Nurses And Doctors, Zahra Tharani, Abeer Musaddique, Syeda Humera Qutb

School of Nursing & Midwifery

No abstract provided.

Exploring The Effects Of Christian Worldviews On Heart Rate, Stress, And Adjustment After Loss In Bereaved Individuals, Emma Radini Ratnavel

Honors Scholar Theses

The objective of this study is to investigate the correlation between Christian values, perceptions of God, and physiological stress, assessed through heart rate, among individuals who are experiencing grief due to the loss of a loved one. Previous studies have analyzed various physiological effects on the body. There are very few studies that examine the correlation between Christian values and heart rate in bereaved participants. To explore these topics further, this study analyzes 59 undergraduate students who have recently lost a loved one, identify as a Christian, and are at least 18 years old. The participants' perceptions of God and …

The Use Of Mindfulness-Based Stress Reduction To Reduce Stress And Burnout In Nurses, Sherri Foreman

MSN Capstone Projects

The Mindfulness-Based Stress Reduction Program (MBSR) has been used effectively in multiple clinical settings to reduce workplace stress and burnout in nurses. The MBSR’s cost-effective approach to stress management can be implemented into any healthcare facility’s policy. The topic of MBSR’s effect on stress and burnout has been identified as essential due to nurses working in fast-paced, stressful work environments. These work environments lead to increased stress and burnout. The International Council of Nurses surveyed nurses before and after the pandemic. There were 40% of nurses that reported symptoms of burnout before the pandemic compared to 70% of nurses after …

Effects Of A Mindfulness Intervention To Improve Teachers’ Well-Being, Andrea P. Almaguer-Botero, Eva L. Miller, Roy K. Chen, Ralph Carlson

School of Rehabilitation Services & Counseling Faculty Publications and Presentations

Teacher attrition has increased by 50% over the past 15 years. The purpose of this study was to determine whether a mindfulness-based intervention would be effective for reducing stress and increasing mindfulness, self-efficacy, job satisfaction, and well-being among teachers at Title I (low-income) schools. The researchers evaluated the effects of a mindfulness intervention created specifically for teachers using a four-way ANOVA (2 × 3 × 2 × 5) with two between subjects’ factors, groups and levels, and two within subjects/repeated measures factors, pretest-posttest and scales. While the study did not show significant effects for mindfulness, stress, self-efficacy, and well-being, teachers …

Comparison Between The Effects Of Acute Physical And Psychosocial Stress On Feedback-Based Learning, Xiao Yang, Brittany Nackley, Bruce H. Friedman

Psychology Faculty Publications

Stress modulates feedback-based learning, a process that has been implicated in declining mental function in aging and mental disorders. While acute physical and psychosocial stressors have been used interchangeably in studies on feedback-based learning, the two types of stressors involve distinct physiological and psychological processes. Whether the two types of stressors differentially influence feedback processing remains unclear. The present study compared the effects of physical and psychosocial stressors on feedback-based learning. Ninety-six subjects (Mage = 19.11 years; 50 female) completed either a cold pressor task (CPT) or mental arithmetic task (MAT), as the physical or psychosocial stressor, while electrocardiography and …

Voluntary Wheel Running Promotes Resilience To The Behavioral Effects Of Unpredictable Chronic Mild Stress In Male And Female Mice., Elias Elias, Ariel Y Zhang, Abigail G White, Matthew J Pyle, Melissa T Manners

Faculty Scholarship for the College of Science & Mathematics

Besides significant benefits to physical health, exercise promotes mental health, reduces symptoms of mental illness, and enhances psychological development. Exercise can offset the impact of chronic stress, which is a major precursor to the development of mental disorders. The effects of exercise on chronic stress-induced behaviors are contradictory in preclinical studies, primarily due to the lack of data and sex-specific investigations. We sought to evaluate the effects of exercise on chronic stress-induced behavioral changes in both male and female mice. Mice were subjected to an Unpredictable Chronic Mild Stress (UCMS) paradigm with accessibility to running wheels for 2 h daily. …

Social Support And Perceptions Of Covid-19-Related Emotional Impact On Mental Health Among Early Adolescents In Appalachia, Hannah M. Layman, Michael J. Mann, Megan L. Smith, Steven M. Kogan, Alfgeir L. Kristjansson

Public Health and Population Science Faculty Publications and Presentations

Background: Young people who experience higher levels of social support from their schools and families have been shown to be less likely to develop symptoms of negative mental health outcomes such as depression and anxiety.1–4 This raises questions concerning how young people's stress and psychological changes due to the COVID-19 pandemic as well as social support during this time have affected their overall mental health. The aim of this study was to assess the association between sources of parental- and school-level social support and youth perceptions of COVID-19-related emotional impact on mental health among early adolescent girls and boys in …

Dnp Final Report: Promoting Physical Activity In Nurse Students, Rose Leal Guidry

DNP Final Reports

Undergraduate nursing students experience educational rigor and challenging clinical experiences that potentially affect stress levels and increase the risk for adverse mental and physical health outcomes. Prolonged stress is associated with emotional exhaustion, unhealthy coping mechanisms, unhealthy behaviors, and impaired functioning. This evidence-based practice project aimed to decrease undergraduate nursing students' perceived stress levels by promoting physical activity. The PICOT question that led this project was in undergraduate nursing students (P), how does the promotion of physical activity (I) compare to no promotion of physical activity (C) affect perceived stress (O) across one semester (T)? The evidence supports physical activity …

Protocol And Biomarker Strategy For A Multi-Site Randomized Controlled Trial Examining Biological Mechanisms And Dosing Of Active Music Engagement In Children With Acute Lymphoblastic Leukemia And Lymphoma And Parents., Sheri L. Robb, Kristen A. Russ, Steven J. Holochwost, Kristin Stegenga, Susan M. Perkins, Seethal A. Jacob, Amanda K. Henley, Jessica A. Maclean

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Music therapy is a standard palliative care service in many pediatric and adult hospitals; however, most research has focused on the use of music to improve psychosocial dimensions of health, without considering biological dimensions. This study builds on prior work examining psychosocial mechanisms of action underlying an Active Music Engagement (AME) intervention, designed to help manage emotional distress and improve positive health outcomes in young children with cancer and parents (caregivers), by examining its effects on biomarkers of stress and immune function.

METHODS: This two-group randomized controlled trial (R01NR019190) is designed to examine biological mechanisms of effect and dose-response …

The Association Of Emotional Eating With Overweight/Obesity, Depression, Anxiety/Stress, And Dietary Patterns: A Review Of The Current Clinical Evidence, Antonios Dakanalis, Maria Mentzelou, Souzana K. Papadopoulou, Dimitrios Papandreou, Maria Spanoudaki, Georgios K. Vasios, Eleni Pavlidou, Maria Mantzorou, Constantinos Giaginis

All Works

(1) Background: Emotional eating is considered as the propensity to eat in response to emotions. It is considered as a critical risk factor for recurrent weight gain. Such overeating is able to affect general health due to excess energy intake and mental health. So far, there is still considerable controversy on the effect of the emotional eating concept. The objective of this study is to summarize and evaluate the interconnections among emotional eating and overweight/obesity, depression, anxiety/stress, and dietary patterns; (2) Methods: This is a thorough review of the reported associations among emotional eating and overweight/obesity, depression, anxiety/stress, and dietary …

Conditioned Place Avoidance Is Associated With A Distinct Hippocampal Phenotype, Partly Preserved Pattern Separation, And Reduced Reactive Oxygen Species Production After Stress, D. Parker Kelley, Lucas Albrechet-Souza, Shealan Cruise, Rajani Maiya, Aspasia Destouni, Siva S.V.P. Sakamuri, Alexander Duplooy, Meghan Hibicke, Charles Nichols, Prasad V.G. Katakam, Nicholas W. Gilpin, Joseph Francis

School of Medicine Faculty Publications

Stress is associated with contextual memory deficits, which may mediate avoidance of trauma-associated contexts in posttraumatic stress disorder. These deficits may emerge from impaired pattern separation, the independent representation of similar experiences by the dentate gyrus-Cornu Ammonis 3 (DG-CA3) circuit of the dorsal hippocampus, which allows for appropriate behavioral responses to specific environmental stimuli. Neurogenesis in the DG is controlled by mitochondrial reactive oxygen species (ROS) production, and may contribute to pattern separation. In Experiment 1, we performed RNA sequencing of the dorsal hippocampus 16 days after stress in rats that either develop conditioned place avoidance to a predator urine-associated …

An Examination Of Discrimination On Stress, Depression, And Oppression-Based Trauma During The Covid-19 Pandemic And The Racial Awakening Of 2020, Ardhys N. De Leon, Jacqueline Woerner, Robert D. Dvorak, Jonathan Cox, Tatiana D. Magri, Emma R. Hayden, Manik Ahuja, Angela M. Haeny

ETSU Faculty Works

Background

Methods

Impact Of Perfectionism, Social Media, And Sleep Hygiene, On Stress In Students From Health Professions Programs, Dayton Duane Braley Spt, Madisyn Ann Dingmann Spt, Brooke Elizabeth Grussing Spt, Justin Daniel Heinrichs Spt, Trystin Renae Nilson Spt

Physical Therapy Student Research Projects

Title: Impact of Perfectionism, Social Media, and Sleep Hygiene, on Stress in Students from Health Professions Programs

Purpose: Explore the impact and relationships of perfectionism, sleep, and social media on stress in health profession students.

Methods: After IRB approval, 62 health pre-professional/professional students completed this non-experimental survey via Qualtrics. The survey consisted of the Perceived Stress Scale (PSS), Frost Multidimensional Perfectionism Scale (FMPS), Pittsburgh Sleep Quality Index (PSQI), questions about social media usage, and demographic characteristics. Surveys were completed in 2021.

Results: Participant demographics included: 50 female, 12 male; Mean Age (24.16); Program of Study (23 PT, 9 OT, 13 …

Associations Between Daily Wellness Behaviors And Outcomes Among Medical Students, Ankrish Milne, Alexandra Novelli, Carly Watson, Hakeem Yousef, William Copeland, Leigh Ann Holterman, Lee Rosen, Yang Bai, Azilee Curl, Samuel Pasqualoni, Stephen Kirby, Xixi Halvorson-Phelan, James Hudziak

Larner College of Medicine Fourth Year Advanced Integration Teaching/Scholarly Projects

Objective: Explore which wellness behaviors have the greatest impact on wellbeing outcomes in medical students.

Methods: A total of 213 medical students were enrolled in this study between June and September 2021. Participants completed a battery of online surveys, including demographic information, and 60-second nightly surveys on the WE-MD smartphone app, which assessed wellness-related indicators (exercise duration, sleep quality, nutrition quality, etc.) and wellbeing outcomes (mood, focus, stress, etc.).

Results: 116 participants completed >50% of nightly surveys between September 2021 and November 2021 and were included in the analysis. All wellness indicators were significantly associated with at least one wellness …

A Lifestyle Management Coaching Intervention For Fear Of Cancer Recurrence In Young Breast Cancer Survivors, Lisa R. Murphy

DNP Research Projects

Abstract

Objective: A significant challenge facing young breast cancer (BC) survivors is learning how to manage fear of cancer recurrence (FCR) during survivorship. Limited tailored FCR interventions and age-appropriate support exist. This Doctor of Nursing (DNP) project, based upon best practice guidelines, aimed to evaluate how a Lifestyle Management Coaching Intervention (LMCI) could help young female BC survivors learn how to decrease and manage their FCR more effectively and experience improved health outcomes.

Method: Eligible participants were female BC survivors aged 18-59 with Stage I-III BC demonstrating elevated baseline FCR screening scores during the extended survival period recruited from the …