Medicine and Health Sciences Commons^™

Factors Affecting Treatment Adherence Among Leprosy Patients: Perceptions Of Healthcare Providers, Veincent Christian F. Pepito, Arianna Maever Loreche, Rae Erica D. Samontina, Sarah Jane A. Abdon, David Norman L. Fuentes, Ofelia P. Saniel

Ateneo School of Medicine and Public Health Publications

Background

Treatment adherence is a vital aspect in the management of chronic diseases like leprosy; however, most studies on treatment adherence focus on patients. This study aims to examine the perceptions of healthcare providers on factors that can promote or prevent patients from adhering to treatment.

Methods

We conducted three focus group discussions (FGDs) with healthcare providers who have at least one year experience in managing leprosy in three large leprosy case-holding hospitals in Metro Manila, Philippines. We audio-recorded, transcribed, translated the FGD proceedings, and analyzed the transcripts thematically to identify patient-intrinsic and patient-extrinsic enablers and barriers to treatment adherence …

Potassium-Incorporated Titanium Oxide Nanoparticles Modulate Human Dendritic Cell Immune Response To Mycobacterium Leprae, Sam Warren, So Yoon Lee, Jose Barragan, Piya Kositangool, Hatsuko Yoshikubo, Jorge Cervantes

HPD Articles

The two polar clinical forms of leprosy, termed tuberculoid and lepromatous, have polarized cellular immune responses with complex immunological distinctions. The predominance of DCs in tuberculoid leprosy has been reported, while the lepromatous pattern of illness is associated with weak activation of local populations of DCs. TiO2 nanoparticles have previously been shown to induce maturation of these cells, leading to an inflammatory response similar to adjuvant usage in vaccine administration. We aimed to evaluate the effect of potassium-incorporated Ti oxide nanostructures, namely KTiOxs, in the response of human monocyte-derived DCs to live M. leprae. Human monocytic cell line dual THP-1, …

Scalp Myiasis In An Ulcerated Abscess In A 7-Year Old Child, Abdullah Khan, Faheem Ullah Khan, Jawad Ahmad, Hameed Ullah, Wiqar Ahmad

Department of Radiology

No abstract provided.

Dirt, Saliva And Leprosy: Anti-Inflammatory And Anti-Infectious Effects, Helieh S. Oz

Internal Medicine Faculty Publications

Ancient Egyptians smeared a mixture of dark soil on their eyelids and believed it protected eyes from unknown forces (illness). Recent studies have proven that the dark soil across the Nile River is rich in natural compounds including lead sulfide, which in low levels, promotes the production of nitric oxide (240-fold) by keratinocytes, with strong immune stimulatory and antimicrobial properties. Current investigations reveal anti-inflammatory and anti-infectious activities—including cytokines and chemokines—in saliva, as well as its friendly microbiota, which lines the surface of the oral cavity, its protection against inflammatory and infectious organisms in the stoma and other organs, such as …