Medicine and Health Sciences Commons^™

Preparation Of Phbv Foams And Investigation Oftheir Potential For Drug Release, Di̇lek Şendi̇l, İhsan Gürsel, Vasif Hasirci

Turkish Journal of Medical Sciences

Polymeric foams seem to have potential for use in many research areas such as cell seeding and macromolecule or drug loading. Three factors were studied to evaluate the efficiency of foams as drug carrier and releasing agents. Effect of polymeric properties was examined by using two types of polymers (PHBV 7 and PHBV 22) differing only in their valerate (copolymer) content. The other factor studied was the effect of loading extent on release kinetics and rate. The results showed an unexpected inverse proportionality between drug loading and release rate. They, however, were in accordance with foam physical properties such as …