Medicine and Health Sciences Commons^™

What's Happening: December 7, 2015, Maine Medical Center

What's Happening

No abstract provided.

Metabolic Patterns In Cancer Cells And Tumor Micro-Environment In Diffuse Large B¬Cell Lymphoma: Tumor–Stromal Metabolic Coupling, Mahasweta Gooptu, Md, Alina E. Dulau Florea, Md, Benjamin E. Leiby, Phd, Barbara Pro, Md, John David Sprandio, Jr. Md, Diana Whitaker-Menezes, Phd, Paolo Cotzia, Md, Guldeep Uppal, Md, Jaime Caro, Md, Jerald Z. Gong, Md, Ubaldo E. Martinez-Outshoorn, Md

Department of Medical Oncology Posters

It has previously been suggested that the tumor microenvironment in diffuse large B-cell lymphoma (DLBCL) has prognostic significance. Furthermore, gene expression profiling in DLBCL patients has identified separate subsets with glycolytic and mitochondrial (oxidative phosphorylative) metabolic signatures.

Glycolytic metabolism forms the basis for FDG PET scans, widely used in staging and response assessment in DLBCL. While many assume that the tumor as a whole is primarily glycolytic, the metabolic patterns of cancer cells (C) and surrounding cancer-associated stromal cells (CAS) remain relatively unknown. We investigated the in situ metabolic patterns of C and CAS cells as well as tumor-associated macrophages …

Physician Executive Leadership: Student-Led Curriculum To Fill Gaps In Traditional Medical Education, Anuj Shah, Ronuk Modi, Jessica Downing, Angela Ugorets, Kathryn Linder, Michael Jacobs, Graham Hale, Jeffrey Fitch, Nicholas Kurtzman, Paul Rosen, Md

Physician Executive Leadership

Students at Sidney Kimmel Medical College (SKMC) have identified a gap in the traditional medical curriculum surrounding topics such as telehealth, the patient experience, health policy, medical malpractice, and health care entrepreneurship and innovation, and in response have initiated a student-centered, student-led, student-driven program called Physician Executive Leadership (PEL). PEL provides students with a variety of avenues to engage with these topics, such as lectures from leaders in each of these fields, easy access to weekly news articles on current events in health care, targeted review sessions on the US health care system, and the opportunity to voice and develop …

Week Of December 7, 2015, New York Medical College

InTouch

• NYMC Honored at WCA Annual Fall Leadership Dinner
• NYMC Hosts Music and Medicine
• HSL Hosts Shakespeare and the Four Humors Presentation
• Meet the Doctor Lecture Series Addresses Concussions in Youth Sports
• New York Blood Center Recognizes NYMC
• StuHE Hosts Public Health Career Mentor Session

Functional Integrity Of Resting-State Networks Predicts Seizure Outcome After Anterior Temporal Lobectomy, Gaelle Doucet, Xiaosong He, Michael R. Sperling, Ashwini Sharan Md, Joseph I. Tracy

Department of Neurosurgery Posters

Rationale

Predicting seizure outcome (SO) after anterior temporal lobectomy (ATL) is a major clinical goal. With clear evidence that even focal epilepsies disrupt large scale brain networks, resting-state functional connectivity (FC) methods have been increasingly used on a pre-surgical basis to characterize the impact of seizures on brain activity. In this project, we sought to determine whether the functional integrity of resting-state networks (RSNs) prior to surgery can discriminate between patients who obtain good versus poor seizure control after ATL.

Daptomycin Non-Susceptible Mrsa Bacteremia: A Case Report, Jaclyn Cusumano, Pharmd, Anna Marie Morlino, Pharmd, Andrew Moyer, Pharmd

College of Pharmacy Posters

Background

Staphylococcus aureus^{1, 2, 3}

• One of the most common pathogens causing community-acquired and nosocomial infections
• Has rapidly developed resistance to many antibiotics:

Daptomycin ²

• Bactericidal cyclic lipopeptide antibiotic
• Possesses negative charge which attracts calcium to form cationic complex
• Interacts with negatively charged phospholipid heads on bacterial cell membranes, leading to membrane depolarization and cell death

Daptomycin non-susceptible (DNS) S. aureus ^{2, 4, 5}

• Extremely rare - About 60 clinical cases reported
• Defined by an MIC greater than 1 mcg/mL
• Potential mechanisms include:

– Changes in cell membrane and cell wall structure alter daptomycin’s permeability²

• Overexpression and dysregulation …

Use Of Core Stabilization Exercise And Medical Exercise Therapy In The Treatment Of A Patient With Chronic Post Partum Low Back Pain: A Case Report, Zachary Chaloner, Kirsten Buchanan

Case Report Posters

Low back pain and lumbar hyper-mobility are common during and after pregnancy. Chronic postpartum low back pain (LBP) can be difficult to manage. Core stabilization exercises (CSE) have been shown to improve function and reduce pain in patients with chronic LBP due to lumbar instability. Medical Exercise Therapy (MET) has shown good outcomes in reducing pain in patients with LBP but has not been thoroughly investigated in the treatment of chronic post partum LBP. There is limited research reporting the use of a combined treatment protocol utilizing CSE and MET in the treatment of chronic LBP in postpartum women. The …

The Effects Of Specific Training On Balance And Ambulation In A Patient With Stage Iv Glioblastoma: A Case Report, Matt Denning

Case Report Posters

Glioblastoma is a malignant brain tumor, often found in the cerebellum. From 2005-2009 there were 109,605 incidences of malignant brain tumors reported in the united states. Specific incidence rates for malignant brain tumors ranged from 5.8 to 11.70 per 100,000 adults 20 years or older. Stage IV is the most rapidly growing and invasive glioblastoma and most common adult neoplasm usually affecting people in the 5th or 6th decade of life. Treatment of glioblastoma frequently involves surgery to excise the tumor followed by radiation therapy. Similar to the growing malignancy these treatments often cause further progressive and even rapid neurological …

The Use Of Aquatic Therapy In Rehabilitation For A Patient Following Complicated Reverse Total Shoulder Arthroplasty: A Case Report, Alyssa Grigware

Case Report Posters

According to the Aquatic Physical Therapy Section of the American Physical Therapy Association, aquatic physical therapy is the evidence-based and skilled practice of physical therapy in an aquatic environment by a physical therapist, and includes interventions designed to improve or maintain: function, aerobic capacity/endurance conditioning, balance, coordination and agility, body mechanics and postural stabilization, flexibility, gait and locomotion, relaxation, muscle strength, power, and endurance. Reverse Total Shoulder Arthroplasty (rTSA) is designed specifically for the treatment of glenohumeral (GH) arthritis when it is associated with irreparable rotator cuff damage, among other complex circumstances. A typical protocol will progress from joint protection, …

Use Of The Lower Extremity Functional Scale (Lefs) In A Patient After A First Metatarsophalangeal Joint Implant: A Case Report, Courtney Brinckman

Case Report Posters

First metatarsolphalangeal (MTP) total joint implants are uncommon; however, hemi implants have increased in popularity. The. HemiCAP® (Franklin, MA) implant resurfaces the metatarsal head while leaving the distal phalanx intact. While early results of the HemiCAP(®) implant surgery have been promising, physical therapy outcome measures such as the LEFS have not been extensively studied in this population. The Lower Extremity Functional Scale (LEFS) is a sensitive and reliable outcome measure that has commonly been used in patients with hip and knee dysfunction. While the LEFS has been used for a broad spectrum of lower-extremity pathologies, there is a paucity of …

Restoring Functional Mobility In A Patient With Delayed Onset Of Physical Rehabilitation Following A Hemorrhagic Stroke: A Case Report, Bettie Kruger, G. Noel Squires

Case Report Posters

Typical rehabilitation post-stroke is initiated as soon as the patient is medically stable. The most dramatic neurological recovery occurs within the first three to six months following medical stabilization. It has been suggested in the literature that early and frequent out of bed activity within the first 24 hours following stroke onset will enhance motor recovery. The patient in this case report was sedentary for three months following the onset of stroke and was non-ambulatory at the time of admission to sub-acute physical therapy. The purpose of this case report is to describe the rehabilitative course, motor recovery, and functional …

The Clinical Decision Making And Outcomes Of A Patient With C7, C8 Radiculopathy And Contralateral Upper Quarter Lateral Epicondylitis: A Case Report, Courtney Naimi

Case Report Posters

Preliminary diagnosis and management strategies exist for both cervical radiculopathy (CR) and lateral epicondylis, however little literature exists describing the clinical decision making and management in the presence of both conditons simultaneously. Management of (CR) (right side) can include neural mobilizations, manual therapy, and exercises. Management of lateral epicondylis (left side) can include eccentric tendinopathy management and manual therapy. The purpose of this case report is to discuss the diagnosis and management for a patient presenting simultaneously with right C7, C8 cervical radiculopathy and contralateral lateral epicondylis.

Functional Skill Training And Group Therapy Treatment Following A Total Hip Arthroplasty In The Acute Care Setting: A Case Report, Heidi Johnson

Case Report Posters

Osteoarthritis (OA) is a very common degenerative condition, often developed during middle and older ages, especially in those with more active lifestyles. Although OA can occur in any joint throughout the body, it most often develops in weight-bearing joints, such as the hip. In 2011 more than 28 million people in the United States were estimated to have OA. OA can lead to pain, stiffness, decreased range of motion, decreased strength, and in turn an overall decline in functional ability. Total hip arthroplasty (THA) is becoming more widely utilized as a means for gaining mobility and independence when a person’s …

Mary Woltemate Stec, Mary Woltemate Stec, Kelsey Duinkerken

Jefferson Nursing Oral Histories

Dr. Stec began her nursing career in 1973 as a graduate of Jefferson’s Nursing Diploma School. She would go on to receive her BS in Nursing from the University of Pennsylvania, her MSN from Gwynedd Mercy College, and her PhD in Nursing from Widener University. Dr. Stec has spent the majority of her career as a nursing educator, including as an instructor at Thomas Jefferson University Hospital School of Nursing, Gwynedd Mercy College, and Abington Memorial Hospital Dixon School of Nursing. She is now an Assistant Professor at Temple University. She is also a Certified Nurse Educator, an Evaluator for …

Katherine Kingsley Kinsey, Katherine Kingsley Kinsey, Kelsey Duinkerken

Jefferson Nursing Oral Histories

Dr. Kinsey received her nursing diploma from the Jefferson Hospital School of Nursing in 1963 and later a BS in Education and School Health from Millersville University. She also has a BS in Nursing, Magna Cum Laude, a MS in Nursing in Community Health, and a PhD in Education, all from the University of Pennsylvania. She currently serves as the Nurse Administrator and Principal Investigator for the Philadelphia Nurse-Family Partnership (NFP), the Mabel Morris Family Home Visit Program (MM), and other early childhood initiatives. Previously, Dr. Kinsey was a tenured professor at La Salle University School of Nursing where she …

Effect Of The Pep Program On Biomechanical Risk Factors In Male Collegiate Lacrosse Athletes, Sebastian Stoltzfus, Casey Cottle, Chad Lyons, Michael A. Lawrence

PEP Program Investigation With Men's Lacrosse Team

Research poster stemming from IPEC mini-grant funded student project Effect of The Prevent Injury Enhance Performance Program on Biomechanical Risk Factors and Performance Variables in Male Collegiate Lacrosse Athletes. Background: Landing and cutting maneuvers are common mechanisms for noncontact anterior cruciate ligament (ACL) injury. Men’s lacrosse is a high risk sport for ACL injury. The Prevent Injury Enhance Performance (PEP) program has been shown to decrease injury rates in women’s soccer but has not been studied in men’s lacrosse. Purpose: Determine if collegiate men’s lacrosse athletes land and cut in ways that put them at risk of ACL tear …

Application Of A Balance Training Program In A Patient With Charcot Marie Tooth Disease: A Case Report, Eduardo Pena

Case Report Posters

Charcot Marie Tooth Disease (CMT) is the most common progressive inherited neurological disease. Proteins in the myelin sheath of both motor and sensory nerves become damaged, resulting in muscle atrophy and reduced sensation. Patients experience difficulty with gait, balance, and independence with ADLs. The RUSK Modified Romberg Program (MRP) is a balance program used for patients with neurological pathologies. There is minimal research on the effectiveness of the RUSK MRP in patients with CMT. The purpose of this case report was to determine the effectiveness of the RUSK MRP in order to improve balance and reduce risk of falls in …

A Task Oriented Approach For A Patient With Chronic Effects Of Stroke: A Case Report, Sarah Richardson, Amy J. Litterini

Case Report Posters

Stroke is the leading cause of serious long-term disability for American adults. Most stroke survivors receive physical therapy (PT) and task-oriented rehabilitation is one novel approach. This technique, which shifts the focus from the impairment level to activity level, is known to benefit stroke survivors. However, the benefits for long-term survivors of stroke are not yet well established. PT professionals would benefit from learning about innovative interventions to improve functional mobility for long-term stroke survivors. The rationale for this report was to document the outcomes of a task-oriented approach to rehabilitation on the late effects of stroke. The unique aims …

The Role Of Physical Therapy In The Treatment And Discharge Of An Elderly Homeless Patient With Fractures Of The T12-L1 Vertebrae: A Case Report, Matthew Kraft

Case Report Posters

More than 600,000 are homeless in the USA. Homeless people have higher rates of premature mortality than the rest of the population, especially from unintentional injuries, and have an increased prevalence of mental disorders. Hospitals often encounter difficulty with discharge when homeless patients are medically stable enough to be transferred to a lower level of care. Hospitals risk potential legal action and poor portrayal by the media if a homeless patient claims he/she was discharged improperly.

Gait Training, Strength Training, And Pain Management Of A 26 Year Old Female Recovering From A Multiple Sclerosis Exacerbation: A Case Report, Ellen Cox

Case Report Posters

Multiple Sclerosis (MS) is an autoimmune disorder where it is thought that the body attacks the myelin sheath covering nerve fibers and disrupts communication in the central nervous system. Presentations are varied with symptoms ranging from loss of vision, poor balance and coordination, tremors, fatigue, pain, and problems with memory and concentration. MS is classified into four types in order of severity: relapsing- remitting, secondary-progressive, primary-progressive, and progressive-relapsing. Evidence links stressful events to increased risk for exacerbations. Treatment of MS can be variable due to the multiple presentations and progressions of disease. Currently little information is available regarding the most …

Progression Magazine, 2015 Winter, Coastal Carolina University

Progression Magazine

Magazine of the College of Science at Coastal Carolina University.

Rehabilitation And Cancer Survivorship, Matthew Denning, Samantha Fisk, Alyssa Grigware, Mary Leopold, Erika Lopez, Margaret Masiak, Sebastian Stoltzfus, Ashley Tomaswick

Disease Prevention and Health Promotion Resources

Presentation given at Central Maine Medical Center on December 4, 2015, to build awareness of the role of rehabilitation services in cancer survivor management and discuss strategies to address existing needs. This presentation was based on a project undertaken to determine which physical distress screening tools are most appropriate to trigger a wellness or rehabilitation referral when it is warranted for a survivor. The use of effective screening tools will assist in directing cancer survivors, who experience physical and emotional burdens caused by the disease and subsequent treatment, to access services that will continue to improve their overall quality of …

Department Of Surgery Update, December 2015, Wright State University Department Of Surgery

Department of Surgery Updates

A four page newsletter created by the Department of Surgery documenting changes to the department. This issue contains a message from the chair, a list of important dates, committee meetings, scholarly activity and more.

Dr. John H. Gibbon, Jr. And Jefferson's Heart-Lung Machine: Commemoration Of The World's First Successful Bypass Surgery, F. Michael Angelo

Posters: Jefferson History

On May 6, 1953 at Jefferson Medical College Hospital, Dr. John Heysham Gibbon, Jr., his staff, and with the help of his latest-designed heart-lung machine, “Model II,” closed a very serious septal defect between the upper chambers of the heart of eighteen-year-old Cecelia Bavolek. This was the first successful intercardiac surgery of its kind performed on a human patient. Ms. Bavolek was connected to the device for three-quarters of an hour and for 26 crucial minutes, the patient totally depended upon the machine’s artificial cardiac and respiratory functions. “Jack” Gibbon did not follow this epoch-making event by holding an international …

African American Graduates Of Jefferson Medical College: The First Hundred Years, F. Michael Angelo

Posters: Jefferson History

Beginnings…

The story of early African American physicians begins in 18th century Philadelphia with James Derham who is recognized as the first black allopathic (regular, non-sectarian) medical doctor. The first medical school in the U.S. to admit an African American was Rush Medical College in Chicago that awarded, in 1847, David J. Peck his degree. Dr. Peck came to the “Quaker City” to set up his practice the same year that the A.M.A. was formed, also here in Philadelphia. In 1877, Jefferson doctors protested the seating of the delegates from Howard University, the nation’s most important black medical school, in …

Latin Heritage Month. Carlos Juan Finlay: Outrageous, Courageous And Correct, Dorothy E. Berenbrok

Posters: Jefferson History

In 1855, a modest Cuban physician named Carlos Juan Finlay graduated from Jefferson Medical College. He was among JMC’s first dozen Hispanic graduates, initially signing the registrar’s log as “Charles”. He left Philadelphia at the age of 22 to begin private practice. Preceptor and close friend S. Weir Mitchell, among others, urged Finlay to work among the burgeoning Spanishspeaking population in New York City, but he returned to Cuba and set up practice in Matanzas, a town near Havana. He took a binocular microscope with him, similar to one used byMitchell, which would serve him well for many years.

During …

United States Medicine, Women And Jefferson Medical College, F. Michael Angelo

Posters: Jefferson History

Timeline of women at Jefferson Medical College.

Labrad : Vol 41, Issue 3 - December 2015, Aga Khan University Hospital, Karachi

LABRAD - Departments of Pathology & Laboratory Medicine and Radiology Archives

• Overview on Approach to Inherited Bleeding Disorders
• Diagnostic Approach to Haemoglobinopathies
• Transient Abnormal Myelopoiesis
• Urinary Tract Infections (UTI) in Children
• Role of Histopathology in the Diagnosis of Paediatric Renal Tumours
• Role of Histopathology in the Diagnosis of Paediatric Bone and Soft Tissue Small Round Cell Tumours
• Evaluation of Inborn Errors of Metabolism (IEM) In a Nutshell
• An Update on Blood Lead Levels in Children
• Clinical Utility of Immature Platelet Fraction – An advanced 25 Parameter in Laboratory Hematology
• Meeting Report: “Les Confluences” The Society for the Study 30 of Inborn errors of Metabolism (SSIEM) Annual Symposium 2015 in Lyon, France

Today - December 2015, Loma Linda University Health

TODAY

Inside this issue:

-- Terrorist bullets shatter the peace of the holidays in San Bernardino and neighboring communities
-- Loma Linda University Health family remembers victims
-- Advancement team Christmas gathering reflects tragedy and hope
-- Media relations ream inundated with inquiries
-- Faculty and students profess solidarity with victims of San Bernardino terrorist attack
-- Flag of Hope promotes unity, peace, and healing
-- Second graders make Christmas cards for LLUMC emergency department
-- Food distribution event at Highland Springs Medical Plaze provides food supplies for local area families in need
-- Charity Navigator gives LLU coveted 4-star rating …

The Scoop, Vol. 2 Issue 9, December 2015, Health Sciences Library

Volume 2

Latest news and events from the Health Sciences Library in our monthly newsletter for December 2015.