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Full-Text Articles in Medicine and Health Sciences
Histopathologic Changes In Liver And Renal Tissues Induced By Different Doses Of Diclofenac Sodium In Rats, Gülsen Aydin, Alparslan Gökçi̇men, Meral Öncü, Ekrem Çi̇çek, Nermi̇n Karahan, Osman Gökalp
Histopathologic Changes In Liver And Renal Tissues Induced By Different Doses Of Diclofenac Sodium In Rats, Gülsen Aydin, Alparslan Gökçi̇men, Meral Öncü, Ekrem Çi̇çek, Nermi̇n Karahan, Osman Gökalp
Turkish Journal of Veterinary & Animal Sciences
Non-steroidal anti-inflammatory drugs (NSAIDs) are in common use worldwide. These drugs may sometimes be used in high or toxic doses by mistake. In this study we investigated the effects of different doses of diclofenac sodium on liver and renal tissues. Forty albino adult male Wistar rats weighing 200 to 220 g were divided equally into four groups. The rats in the control group (n = 10) were each intramuscularly injected with 1 cc of physiologic saline. The other three groups were given diclofenac sodium doses. The rats in the first (n = 10), second (n = 10) and third (n …
The Effects Of Replacing Fish Oil With Vegetable Oils In Starter Feeds On The Liver Fat Composition Of Sea Bass (Dicentrarchus Labrax L., 1758), Mustafa Yildiz, Erdal Şener
The Effects Of Replacing Fish Oil With Vegetable Oils In Starter Feeds On The Liver Fat Composition Of Sea Bass (Dicentrarchus Labrax L., 1758), Mustafa Yildiz, Erdal Şener
Turkish Journal of Veterinary & Animal Sciences
The effects of replacing fish oil with soybean oil, sunflower oil, corn oil and olive oil in starter feeds on the vicerosomatic index, hepatosomatic index and liver fatty acid composition of the sea bass were studied. Juvenile sea bass (initial weight = 7.58 ± 0.13 g) were fed experimental diets for 75 days. The fish were then killed and liver samples were collected. The lowest total crude fat value (17.61%) was found in the fish fed the fish oil diet. The highest total crude fat value (34.30%) was found in the fish fed the olive oil diet (P < 0.05). Similarly, the fish fed the fish oil diet had the lowest hepatosomatic index value (2.08) and all the fish fed vegetable oils had similarly high hepatosomatic index values (P < 0.05). Likewise, vicerosomatic index values were lowest (9.06%) in the fish fed fish oil and highest in the fish fed soybean and other vegetable oils (P < 0.05). Fatty acid analyses showed that EPA and DHA from n-3 HUFA's in the fish fed the fish oil diet, linolenic acid (18:3n-3) and linoleic acid (18:2n-6) in the fish fed the soybean oil diet and oleic acid (18:1n-9) in the fish fed the olive oil diet were higher than in the fish fed the other diets.
Hepatorenal Syndrome And Efficiency Of Aldosterone Receptor Blockade On Hepatorenal System And Systemic Hemodynamics In Dogs With Experimentally Induced Hepatic Cirrhosis, Remzi̇ Gönül, Utku Bakirel, Abdullah Kayar, Yücel Meral, Mehmet Erman Or, Gülbi̇n Şennazli, Aydin Gürel, Emi̇ne Akdeni̇zli̇
Hepatorenal Syndrome And Efficiency Of Aldosterone Receptor Blockade On Hepatorenal System And Systemic Hemodynamics In Dogs With Experimentally Induced Hepatic Cirrhosis, Remzi̇ Gönül, Utku Bakirel, Abdullah Kayar, Yücel Meral, Mehmet Erman Or, Gülbi̇n Şennazli, Aydin Gürel, Emi̇ne Akdeni̇zli̇
Turkish Journal of Veterinary & Animal Sciences
In this study, the clinical signs of hepatorenal syndrome that occurs during hepatic cirrhosis were investigated and a variety of diagnosis and therapy methods were investigated in the experimentally ligated bile ducts of dogs. The test group with ligated bile ducts (n = 14) and the sham operated control group (n = 14) were divided into 2 sub groups and administered a derivative of spironalactone (Aldoctan® tablet), an antagonist of the aldosteron receptor, at 1.5 mg/kg daily for 5 weeks. Hepatorenal changes and the systemic effects of the drug were determined by comparing the control and test groups during the …