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A Comparison Of The Effects Of Hyperbaric And Isobaric Bupivacaine Spinal Anesthesia On Hemodynamics And Heart Rate Variability, Mehmet Toptaş, Si̇nan Uzman, İlke İşi̇temi̇z, Tümay Uludağ Yanaral, İbrahi̇m Akkoç, Gülşen Bi̇can
A Comparison Of The Effects Of Hyperbaric And Isobaric Bupivacaine Spinal Anesthesia On Hemodynamics And Heart Rate Variability, Mehmet Toptaş, Si̇nan Uzman, İlke İşi̇temi̇z, Tümay Uludağ Yanaral, İbrahi̇m Akkoç, Gülşen Bi̇can
Turkish Journal of Medical Sciences
To compare the effects of hyperbaric and isobaric bupivacaine spinal anesthesia on hemodynamics and heart rate variability (HRV) in nonobstetric surgery. Materials and methods: Sixty patients were randomly allocated to 2 groups. Group I (n = 30) received 15 mg (3 mL) of hyperbaric bupivacaine and Group II (n = 30) received 15 mg (3 mL) of isobaric bupivacaine for spinal anesthesia. Hemodynamic parameters were recorded before and after spinal anesthesia over 30 min. Analyses of HRV were performed on the day of surgery, after volume loading, and 20 min after spinal injection. Low frequency (LF) values, high frequency (HF) …
Comparison Of Intraarticular Bupivacaine And Levobupivacaine Injection In Rat Synovial Inflammation, Beki̇r Suat Kürkçüoğlu, Melahat Dönmez, Seher Altinel, Seda Banu Akinci, Fatma Saricaoğlu, Ülkü Aypar
Comparison Of Intraarticular Bupivacaine And Levobupivacaine Injection In Rat Synovial Inflammation, Beki̇r Suat Kürkçüoğlu, Melahat Dönmez, Seher Altinel, Seda Banu Akinci, Fatma Saricaoğlu, Ülkü Aypar
Turkish Journal of Medical Sciences
Both bupivacaine and levobupivacaine are local anesthetics with strong analgesic efficacy that can be used intraarticularly. The aim of this study was to compare the effects of intraarticular bupivacaine and levobupivacaine injection on inflammation in articular cartilage and the synovium of the rat knee joint. Materials and methods: Twenty Sprague-Dawley rats were injected in the right knee joint with 0.2 mL of bupivacaine, while 0.2 mL of levobupivacaine was injected into the left knee joint. Groups of 5 were sacrificed on days 1, 7, 14, and 21 after bupivacaine and levobupivacaine administration and knee joints were examined for subintimal fibrosis, …