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Full-Text Articles in Medicine and Health Sciences
Gut Microbiota And Therapeutic Approaches For Dysbiosis In Irritable Bowel Syndrome:Recent Developments And Future Perspectives, Hanna Fjeldheim Dale, Gülen Arslan Lied
Gut Microbiota And Therapeutic Approaches For Dysbiosis In Irritable Bowel Syndrome:Recent Developments And Future Perspectives, Hanna Fjeldheim Dale, Gülen Arslan Lied
Turkish Journal of Medical Sciences
Increased knowledge regarding the implications of gut microbiota in irritable bowel syndrome (IBS) suggests that a disturbed intestinal microenvironment (dysbiosis) might promote the development and maintenance of IBS symptoms and affects several pathways in the pathology of this multifactorial disease. Accordingly, manipulation of the gut microbiota in order to improve IBS symptoms has evolved as a novel treatment strategy in the last decade. Several different approaches have been investigated in order to improve the gut microbiota composition. Dietary modifications including supplementation with fibers, prebiotics, and probiotics are shown to improve symptoms and composition of gut microbiota in IBS; however, the …
Should Antibiotics Be Administered After Endoscopic Mucosalresection In Patients With Colon Polyps?, Zhimeng Shi, Hui Qiu, Huangang Liu, Honggang Yu
Should Antibiotics Be Administered After Endoscopic Mucosalresection In Patients With Colon Polyps?, Zhimeng Shi, Hui Qiu, Huangang Liu, Honggang Yu
Turkish Journal of Medical Sciences
Background/aim: Endoscopic mucosal resection (EMR) is widely used for treating gastrointestinal polypoid lesions. However, it is currently unclear whether antibiotic administration is necessary after EMR of colon polyps to prevent infection. We aimed to assess whether antibiotic administration is essential in such conditions. Materials and methods: In total, 115 patients with colon polyps were randomly assigned to 3 groups based on the treatment given after EMR: Group A, no antibiotics treatment after EMR (n = 38); Group B, administration of levofloxacin after EMR (n = 38); and Group C, administration of ceftazidime after EMR (n = 39). Results: The colon …
Investigation Of The Inhibition Effects Of Someantibiotics On Human Erythrocytecarbonic Anhydrase Isozymes, T. Abdülkadir Çoban, Barbaros Nalbantoğlu, M. Yaşar Çi̇l, Hasan Özdemi̇r, Ö. İrfan Küfrevi̇oğlu
Investigation Of The Inhibition Effects Of Someantibiotics On Human Erythrocytecarbonic Anhydrase Isozymes, T. Abdülkadir Çoban, Barbaros Nalbantoğlu, M. Yaşar Çi̇l, Hasan Özdemi̇r, Ö. İrfan Küfrevi̇oğlu
Turkish Journal of Medical Sciences
In this study, the in vitro effects of some antibiotics on carbonic anhydrase (CA) isozymes have been investigated. Human erythrocyte CA-I and CA-II isozymes were separately purified by affinity chromatography. Inhibition effects of four different antibiotics on CA isozymes were determined by using the CO 2 -Hydratase method. I 50 values of antibiotics were obtained by drawing % Activity [Actibiotic] graphs. The obtained I 50 values of cefazolin sodium, cephradine, sulbactam/cefoperazone and chloramphenicol sodium succinate were 9, 16, 19 and 48 mM on CA-I and 6, 10, 15 and 17 mM on CA-II, respectively. Antibiotics dosages should be taken into …