Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 2 of 2
Full-Text Articles in Medicine and Health Sciences
Pain, Depression Levels, Fatigue, Sleep Quality, And Quality Of Life Inelderly Patients With Rheumatoid Arthritis, İlknur Albayrak Gezer, Ayşe Balkarli, Beray Can, Si̇nan Bağçaci, Sami̇ Küçükşen, Adem Küçük
Pain, Depression Levels, Fatigue, Sleep Quality, And Quality Of Life Inelderly Patients With Rheumatoid Arthritis, İlknur Albayrak Gezer, Ayşe Balkarli, Beray Can, Si̇nan Bağçaci, Sami̇ Küçükşen, Adem Küçük
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to evaluate and determine the relationships (if any) among pain, depression levels, fatigue, sleep quality, and quality of life in patients with rheumatoid arthritis (RA) aged 65 years and over, and to compare the results with those of RA patients under 65 years of age. Materials and methods: The study included 52 patients with RA aged 65 years and over (Group 1) and 84 patients with RA under 65 years of age (Group 2). Pain, depression levels, fatigue, sleep quality, quality of life, and disease activity of all of the participants were evaluated …
Antiinflammatory And Antioxidant Effects Of Gemcitabinein Collagen-Induced Arthritis Model, Adi̇le Ferda Dağli, Ahmet Karataş, Cemal Orhan, Mehmet Tuzcu, Meti̇n Özgen, Kazi̇m Şahi̇n, Süleyman Serdar Koca
Antiinflammatory And Antioxidant Effects Of Gemcitabinein Collagen-Induced Arthritis Model, Adi̇le Ferda Dağli, Ahmet Karataş, Cemal Orhan, Mehmet Tuzcu, Meti̇n Özgen, Kazi̇m Şahi̇n, Süleyman Serdar Koca
Turkish Journal of Medical Sciences
Background/aim: Gemcitabine (GEM) has antiproliferative effects on lymphocytes, which are potent pathogenic actors of rheumatoid arthritis (RA). The aim of the study was to investigate the therapeutic potential of GEM on collagen-induced arthritis (CIA). Materials and methods: Arthritis was induced by the intradermal injection of chicken type II collagen with incomplete Freund's adjuvant into albino Wistar rats. Doses of 5 and 20 mg/kg GEM were administered twice a week after the 14th day, which marked the onset the arthritis. Serum IL-17, TNF-α, malondialdehyde, catalase, superoxide dismutase (SOD), and glutathione peroxidase (GPx) levels and tissue heme oxygenase-1 (HO-1) and nuclear factor …