Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 1 of 1
Full-Text Articles in Medicine and Health Sciences
Correlation Between Down Syndrome And The Level Of Placental Alkaline Phosphatase In Amniotic Fluid, Canan Uçar, Sevi̇m Balci, Ergül Tunçbi̇lek, İbrahi̇m Ünsal
Correlation Between Down Syndrome And The Level Of Placental Alkaline Phosphatase In Amniotic Fluid, Canan Uçar, Sevi̇m Balci, Ergül Tunçbi̇lek, İbrahi̇m Ünsal
Turkish Journal of Medical Sciences
The aim of this study was to investigate the correlation between Down syndrome and the level of placental alkaline phosphatase (PLAP) in amniotic fluid. A total of 279 amniotic fluid samples taken between 14 and 24 gestational weeks were investigated in this study. Karyotype analysis was made in all samples. In 10 samples trisomy 21 was determined, in one sample trisomy 18, in two samples 47,XXY, in six samples various structural chromosomal anomalies and in 260 samples normal karyotype. PLAP was measured using a fluorometric heat inactivation assay. Mean PLAP multiples of normal gestational median (MOM) value in samples with …