Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 1 of 1
Full-Text Articles in Medicine and Health Sciences
In Vitro Testing For Genotoxicity Of 4-Cpa By Sister Chromatid Exchange In Human Lymphocyte Culture, Hüseyi̇n Bağci, Gülseren Bağci, İbrahi̇m Açikbaş, Göksemi̇n Demi̇r
In Vitro Testing For Genotoxicity Of 4-Cpa By Sister Chromatid Exchange In Human Lymphocyte Culture, Hüseyi̇n Bağci, Gülseren Bağci, İbrahi̇m Açikbaş, Göksemi̇n Demi̇r
Turkish Journal of Medical Sciences
Certain phenoxyacetate derivatives used as plant growth regulators act as plant hormones. 2,4-D dichlorophenoxyacetic acid and 4-chlorophenoxyacetic acid are widely used in vegetable growing, especially tomatoes, in our region. These phenoxyacetic acid compounds are a potential hazard for the environment. There are conflicting results and inconsistent data about these herbicides in the literature. This is the first report of genotoxicity of 4-CPA evaluated by sister chromatid exchange in human lymphocyte culture. No significant change was found in sister chromatid exchange frequency at the tested 4-CPA concentration.