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Articles 1 - 30 of 138
Full-Text Articles in Medicine and Health Sciences
The Effect Of Fish Oil On Liver And Plasma Mda And Antioxidant Status Of Rats, Nuriye Mete, Birgül Işik, Levent Erdi̇nç, Fuat Gürkan
The Effect Of Fish Oil On Liver And Plasma Mda And Antioxidant Status Of Rats, Nuriye Mete, Birgül Işik, Levent Erdi̇nç, Fuat Gürkan
Turkish Journal of Medical Sciences
The question how fish oil (FO) and soybean oil (SO) change the state of antioxidant and the lipid peroxidation in liver and plasma of rats and the protective role of vitamin E were investigated. Six-week-old forty male Sprague-Dawley rats were divided into five groups. One of the groups fed a control diet, another one fed SO, while the other three groups fed FO diet at the level of 10% Vitamin E supplementation was maintained to three different levels 3, 50, 150 IU/per kg diet in the FO diets and 3 IU vitamin E per kg of the SO diet. At …
Quantification Of Total Collagen In Rabbit Tendonby The Sirius Red Method, Dilek Taşkiran, Emin Taşkiran, Hüseyin Yercan, Fatma Z. Kutay
Quantification Of Total Collagen In Rabbit Tendonby The Sirius Red Method, Dilek Taşkiran, Emin Taşkiran, Hüseyin Yercan, Fatma Z. Kutay
Turkish Journal of Medical Sciences
No abstract provided.
Agnors, Pcna And Histologic Activity Index Inchronic Liver Disease, Koray Ceyhan, İlkser Akpolat, İbrahim Kobat, Nazan Bozdoğan, Selim Erekul
Agnors, Pcna And Histologic Activity Index Inchronic Liver Disease, Koray Ceyhan, İlkser Akpolat, İbrahim Kobat, Nazan Bozdoğan, Selim Erekul
Turkish Journal of Medical Sciences
Chronic hepatitis is a clinical and pathological syndrome, which has several causes and it is characterized by varying degrees of hepatocellular necrosis and inflammation. Several systems have been proposed to evaluate the diagnosis, grading and staging of chronic hepatitis. A histologic activity index (HAI) has been developed which generates a numerical score for liver biopsy specimens obtained from patients with chronic hepatitis. The aim of this study was to evaluate the correlation between HAI and proliferative activity markers, such as PCNA and AgNORs in biopsy specimens obtained from patients with chronic liver disease including chronic hepatitis and cirrhosis. Mean AgNOR …
Diurnal Variation Of Methotrexatepharmacokinetics In Adults With Osteosarcoma, Necdet Soykan, Mehtap Çinar, Cenk Can, Banu Çiçek Bi̇lkay
Diurnal Variation Of Methotrexatepharmacokinetics In Adults With Osteosarcoma, Necdet Soykan, Mehtap Çinar, Cenk Can, Banu Çiçek Bi̇lkay
Turkish Journal of Medical Sciences
The daytime and nighttime dispositions of high dose (12 g/m 2 ) methotrexate were examined in 8 osteosarcoma patients. The plasma and renal clearances, urine pH values and area under the curves were compared. The plasma clearance of methotrexate tended to fall after it was administered at (from 1.74±0.06 ml/min/kg to 0.47±0.01 ml/min/kg, p
The Role Of Plasma Endothelin-1 In Preeclampsia, Yalçın Ki̇mya, Candan Cengi̇z, Hakan Ozan, Levent Büyükuysal, Sami Aydin, Serhat Tatlikazan
The Role Of Plasma Endothelin-1 In Preeclampsia, Yalçın Ki̇mya, Candan Cengi̇z, Hakan Ozan, Levent Büyükuysal, Sami Aydin, Serhat Tatlikazan
Turkish Journal of Medical Sciences
Endothelin-1 levels in normal and preeclamptic pregnant women were determined serially to investigate the correlation between renal function tests and the severity markers of preeclampsia. Plasma endothelin-1 levels were determined in 45 serial plasma samples from 15 pregnant women who subsequently developed preeclampsia, and in 43 plasma samples from 25 women with uncomplicated pregnancies retrospectively. Renal function tests, complete blood counts, urinalysis and blood pressure measurements were performed during antenatal follow-ups of these patients. No correlations were set between plasma endothelin-1 levels and renal function tests, thrombocyte and white blood cell counts, proteinuria, systolic and diastolic blood pressures. There was …
Serum Il-6 And Tnf-\Alpha In Patients With Thyroid Disorders, Ahmet Kiziltunç, Mahmut Basoğlu, Bahattin Avci, İlyas Çapoğlu
Serum Il-6 And Tnf-\Alpha In Patients With Thyroid Disorders, Ahmet Kiziltunç, Mahmut Basoğlu, Bahattin Avci, İlyas Çapoğlu
Turkish Journal of Medical Sciences
The study was designed to evaluate IL-6 and TNF-\alpha levels and to examine their relationship in 27 patients with hyperthroidism, 23 with hypothyroidism, and 18 with normal thyroid functions. Mean serum levels of IL-6 and TNF-\alpha in patients with untreated hyperthyroidism were higher than those of control group (p
Interictal Spect With Tc 99m-Hm Pao In Migrainepatients, Meral Mi̇rza, Ahmet Tutuş, Füsun Erdogan, Mustafa Kula, Ali Tomar, Güler Silov, Emel Köseoğlu
Interictal Spect With Tc 99m-Hm Pao In Migrainepatients, Meral Mi̇rza, Ahmet Tutuş, Füsun Erdogan, Mustafa Kula, Ali Tomar, Güler Silov, Emel Köseoğlu
Turkish Journal of Medical Sciences
Migraine is considered to be a functional neurological disorder. For several years cerebral blood flow studies have been fueling the controversy surrounding the pathophysiology of migraine headache. Tc 99m-HM PAO SPECT brain imaging was performed during the headache-free period of 29 migraine sufferers (24 without aura, 5 with aura). The findings were compared with those of an age-and sex-matched control group of 17 people. The SPECT images revealed clear interhemispheric asymmetry in the right frontal, temporal and occipital lobes of the brain in the study group. Slight hypoperfusion was observed in patients who had interictal EEG abnormalities.
Serum D(-)-Lactate And Nitric Oxide (No) Levels Inacute Intestinal Ischemia, Mahmut Basoğlu, Ahmet Balik, Ahmet Kiziltunç, Fatih Akçay, Selçuk Sabri Atamanalp
Serum D(-)-Lactate And Nitric Oxide (No) Levels Inacute Intestinal Ischemia, Mahmut Basoğlu, Ahmet Balik, Ahmet Kiziltunç, Fatih Akçay, Selçuk Sabri Atamanalp
Turkish Journal of Medical Sciences
To determine serum D(-)-lactate and NO levels in patients with acute mesenteric ischemia. 22 patients (12 with acute mesenteric ischemia, 10 with bowel obstruction) and 12 control patients who were operated due to goitre. Serum D(-)-lactate and NO levels in acute mesenteric ischemia cases compared to small bowel obstruction cases and control patients. Increased serum D(-)-lactate and NO levels in serum levels of ischemic bowel were found to be significantly increased compared to both the cases with small bowel obstruction and control subjects (for D(-)-lactate: p
Effect Of Psychological Stress On Nasal Immunity, Erdal Seren, Abdülcemal Ümit Işik, Mehmet İmamoglu, Osman Bahadir, Mehmet Arif Köroğlu, Yavuz Tekeli̇oğlu
Effect Of Psychological Stress On Nasal Immunity, Erdal Seren, Abdülcemal Ümit Işik, Mehmet İmamoglu, Osman Bahadir, Mehmet Arif Köroğlu, Yavuz Tekeli̇oğlu
Turkish Journal of Medical Sciences
Stress activates the hypotalamic-pituitary- adrenal axis, increases circulating glucocorticoids, and is associated with alterations in immune functions. Nasal mucosa is richly innervated by sympathetic nerve fiber and nasal patency changes in response to various sympathetic stimuli. These fibres form close neuroeffector junctions with lymphocytes and macrophages. Nasal lavage and peripheral blood samples were collected from healthy medical students one hour before their exams and a week later, after the declaration of results of the exams were announced. We determined and compared the distribution of T lymphocyte subsets in students under psychological stress The T cell: natural killer cell, T helper …
The Assessment Of Anthropometrical Measurements Of Newborns And The Incidence Of Fetal Malnutrition In Erzurum Region, Zerrin Orbak, Hüseyin Tan, Nevin Sağsöz, Fatih Zor
The Assessment Of Anthropometrical Measurements Of Newborns And The Incidence Of Fetal Malnutrition In Erzurum Region, Zerrin Orbak, Hüseyin Tan, Nevin Sağsöz, Fatih Zor
Turkish Journal of Medical Sciences
We included in this study 1100 newborns whose gestational ages were between 26 and 42 weeks. Of these infants, 323(29.4%) were preterm. The others 777(70.6%) were term infants. In term newborns, the mean weight, length, head circumference and ponderal indexes of males were significantly higher than those of females (p
Nosocomial Urinary Tract Infections In Children, Ayse Balat, L. Leighton Hill
Nosocomial Urinary Tract Infections In Children, Ayse Balat, L. Leighton Hill
Turkish Journal of Medical Sciences
Nosocomial infections are a major cause of morbidity and mortality in hospitalized children, and the urinary tract is one of the most common sites of these infections. We retrospectively reviewed the charts of 1,221 children discharged with a diagnosis of urinary tract infection (UTI) from July 1, 1991 to June 30, 1994. Of the 1,221 UTIs, there were 137 (11.2%) cases of nosocomial UTI (NUTI) in 136 patients. NUTI accounted for 0.28% of all discharges (48, 382 patients) at a single institution over the 3-year period studied. There were 75 girls and 61 boys. The mean age was 4.4 years …
Genitourinary Abnormalities In Children With Urinary Tract Infections, Ayşe Balat, L. Leighton Hill
Genitourinary Abnormalities In Children With Urinary Tract Infections, Ayşe Balat, L. Leighton Hill
Turkish Journal of Medical Sciences
Urinary-tract infections (UTI) are common infectious diseases in childhood. The presence of UTI may be an indicator of a serious genitourinary (GU) abnormality that requires medical intervention. We retrospectively reviewed the charts of children discharged with a diagnosis of UTI from the Texas Children's Hospital, Houston, Texas, between July 1, 1991 and June 30, 1994. The purpose of the study was to determine how many patients had underlying GU abnormalities, the specific type of abnormality, and the microorganism causing the UTI. During the 3-year period, there were 48,382 discharges from the hospital, and 1,221 (2.5%) of those discharges were patients …
Infectious Diseases Concomitant With Urinary Tract Infections In Children, Ayşe Balat, L. Leighton Hill
Infectious Diseases Concomitant With Urinary Tract Infections In Children, Ayşe Balat, L. Leighton Hill
Turkish Journal of Medical Sciences
Urinary-tract infection (UTI) is one of the most common infectious diseases in children; however, the significance of combined infection in the pathogenesis of UTI remains uncertain. Of 48,382 patients discharged from Texas Children's Hospital from July 1, 1991, to June 30, 1994, 1,221 (2.5%) were discharged with a diagnosis of UTI. We retrospectively reviewed the files of these 1,221 patients to assess for concomitant infections and causative microorganisms in patients with first-time UTI, no urologic abnormalities, and no other major diagnoses. Of the 1,221 patients, 511 (42%) had first-time UTI with no urological abnormalities or other major diagnoses, of which …
Pupil Cycle Time In Children With Nocturnal Enuresis, Cengiz Yakinci, Hamdi Er, Bülent Müngen, Yaşar Durmaz, Hamza Karabi̇ber
Pupil Cycle Time In Children With Nocturnal Enuresis, Cengiz Yakinci, Hamdi Er, Bülent Müngen, Yaşar Durmaz, Hamza Karabi̇ber
Turkish Journal of Medical Sciences
No abstract provided.
A Case Of Pheochromocytoma Manifested As Noncardiogenic Pulmonary Edema, Tuncer Tuğ, Necmi Özdemi̇r, Vedat Bulut, Aziz Karaoğlu, M.Hamdi Muz
A Case Of Pheochromocytoma Manifested As Noncardiogenic Pulmonary Edema, Tuncer Tuğ, Necmi Özdemi̇r, Vedat Bulut, Aziz Karaoğlu, M.Hamdi Muz
Turkish Journal of Medical Sciences
Pheochromocytoma is known as chromaffin cell tumor frequently originated from adrenal medulla and results in hypersecretion of catecholamines (1). Typical clinical findings include headache, palpitation, excessive sweating and paroxysmal hypertension, which persistently maintains in 60% of the cases. Generally, paroxysm or attacks are often, but they can appear with intervals of weeks or months (1, 2). Additionally, tachycardia, bradycardia and/or fatal arrhythmia, acute myocard infarcts, spasms in coroner arteries, carcinoid-like manifestations, hyperamilasemi, acute abdomen, chest pain, intolerance to carbohydrates, nephritic syndrome (very rare), cardiac pulmonary edema, cardiomyopathie caused by catecholamines and very rarely noncardiogenic pulmonary edema may develop (3, 4, …
Hydrotic Ectodermal Dysplasia(Associated With Numerous Enclusedpermanent Teeth Including A Primary Molar), Ali Rıza Alpöz
Hydrotic Ectodermal Dysplasia(Associated With Numerous Enclusedpermanent Teeth Including A Primary Molar), Ali Rıza Alpöz
Turkish Journal of Medical Sciences
No abstract provided.
Percutaneous Retrieval Of Broken Port Catheterentrapped In The Right Atrium, Ahmet Memi̇ş, İsmail Oran, Vahit Özener
Percutaneous Retrieval Of Broken Port Catheterentrapped In The Right Atrium, Ahmet Memi̇ş, İsmail Oran, Vahit Özener
Turkish Journal of Medical Sciences
No abstract provided.
Comparative Genomic Hybridization (Cgh) Incancer Research, İbrahi̇m Keser
Comparative Genomic Hybridization (Cgh) Incancer Research, İbrahi̇m Keser
Turkish Journal of Medical Sciences
Cancer is a multifactorial and multistep process. Conventional cytogenetics has become a major working field in cancer research. Chromosome rearrangements are recognized as critical in the pathogenesis of human cancer. Molecular biology and molecular cytogenetics technology have increased our ability to identify genetic alterations in cancer cells. Polymerase chain reaction (PCR), fluorescence in situ hybridization (FISH), oligonucleotide-primed in situ DNA synthesis (PRINS) are the most common molecular cytogenetic procedures in cancer research but they have limits with precise localization in their principles in cancer researching. However, comparative genomic hybridization (CGH) is a powerful molecular cytogenetic technique which allows the analysis …
Mao Inhibitors In Aging: Can They Serve As Protective Agents In Cardiac Tissue Against Oxidative Stress?, Ferhan Külahçioğlu Gi̇rgi̇n, Mert Özgönül, Güli̇nnaz Alper, Gülri̇z Menteş, Bi̇ltan Ersöz, Eser Yildirim Sözmen
Mao Inhibitors In Aging: Can They Serve As Protective Agents In Cardiac Tissue Against Oxidative Stress?, Ferhan Külahçioğlu Gi̇rgi̇n, Mert Özgönül, Güli̇nnaz Alper, Gülri̇z Menteş, Bi̇ltan Ersöz, Eser Yildirim Sözmen
Turkish Journal of Medical Sciences
Biological damage mediated by reactive oxygen species has been increasingly recognized in aging phenomena in recent decades. The increase in catecholamine metabolism is yet another physiological change in aging, predisposing the organism to supranormal hydrogen peroxide produc-tion as a by-product. This study was undertaken to investigate the alterations in oxidant- antioxidant status in rat cardiac tissue during aging. The effects of acute administration of monoamine oxidase (MAO) inhibitors on this status were also investigated to find possible preventive strategies in conjugate aging. MAO activities, malondialdehyde MDA and diene conjugate levels as well as superoxide dismutase and catalase activities were determined …
Effect Of Exercise On Blood Antioxidant Status And Erythrocyte Lipid Peroxidation: Role Of Dietary Supplementation Of Vitamin E, Mustafa Kelle, Hüda Di̇ken, Abdurrahman Şermet, Mukadder Atmaca, Cemi̇l Tümer
Effect Of Exercise On Blood Antioxidant Status And Erythrocyte Lipid Peroxidation: Role Of Dietary Supplementation Of Vitamin E, Mustafa Kelle, Hüda Di̇ken, Abdurrahman Şermet, Mukadder Atmaca, Cemi̇l Tümer
Turkish Journal of Medical Sciences
We tested the effects of moderate physical exercise on the blood antioxidant capacity and erythrocyte lipid peroxidation in 21 Wistar albino rats. Erythrocyte superoxide dismutase (SOD) activity increased significantly (p
Effect Of Dehydration On The Pharmacokinetics Of Mefenamic Acid, Shadab Qamar, Nadeem Irfan, Mahmood Ahmad, Muhammad Jamshaid, Naeem A. Muzaffar
Effect Of Dehydration On The Pharmacokinetics Of Mefenamic Acid, Shadab Qamar, Nadeem Irfan, Mahmood Ahmad, Muhammad Jamshaid, Naeem A. Muzaffar
Turkish Journal of Medical Sciences
The pharmacokinetic properties and bioavailability of mefenamic acid was studied in normal and dehydrated rabbits. High perfomance liquid chromatography (HPLC) was used for the assay of mefenamic acid in plasma samples. The mean plasma concentration and area under the plasma concentration-time curve decreased but the volume of distribution and total body clearance increased significantly (P
Effects Of Nerve Growth Factor On Acetylcholinesterase Activity Of Injured Spinal Cord, Süleyman Baykal, Savaş Ceylan, Haydar Usul, Yüksel Ali̇yazicioğlu, Hasan Efe, Kayhan Kuzeyli̇, Soner Duru, Fadil Aktürk
Effects Of Nerve Growth Factor On Acetylcholinesterase Activity Of Injured Spinal Cord, Süleyman Baykal, Savaş Ceylan, Haydar Usul, Yüksel Ali̇yazicioğlu, Hasan Efe, Kayhan Kuzeyli̇, Soner Duru, Fadil Aktürk
Turkish Journal of Medical Sciences
Fourteen rats were examined and divided into two groups of 7: the control (Group a) and NGF-treated animals (Group B). All animals received a 50 g clip-compression injury to tthe spinal cord at the T9 level. In the NGF-treated animals, NGF (0.1 mg/kg NGF) was injected subcutaneously for seven days. After spinal cord injury, the mean AChE activity was 41.47±1.7122 activated substrate min/ml/gr. wet tissue and 47.52±1.471 in NGF-treated animals. The difference between Groups A and B was statistically significant (p
Administration Of Granulocyte Colonystimulating Factor (G-Csf) In Experimentallyinfected Rats, Ömer Cevi̇t, Ruhi̇ye Cevi̇t, Gökhan Köylüoğlu, Di̇lara İçağasioğlu, Asim Gülteki̇n, Fatoş Tanzer
Administration Of Granulocyte Colonystimulating Factor (G-Csf) In Experimentallyinfected Rats, Ömer Cevi̇t, Ruhi̇ye Cevi̇t, Gökhan Köylüoğlu, Di̇lara İçağasioğlu, Asim Gülteki̇n, Fatoş Tanzer
Turkish Journal of Medical Sciences
We investigated the effect of antibiotic or G-CSF plus antibiotic therapy given to E. coli septic rats. In our study, 80 rats were inoculated transperitoneally with 1 ml of a solution containing 10 7 colony forming units per milliliter of E. coli. Rats were divided into four treatment groups before being inoculaded with E. coli in a random fashion. Therapy was then started with cefotaxime (150 mg/kg intraperitonelally) and either Granulocyte-Colony Stimulation Factor (G-CSF; 30 µg/kg intarperitoneally) or placebo 24 hours after inoculation of E. coli for 3 consective days. Group A 1 , sepsis-antibiotics group, had a mortality rate …
The Effect Of Acute Exercise On Skin Potential In Trained Athletes, Uğur Tarik Turaçlar, Sena Erdal, Abdullah Arslan, Ahmet Yildiz
The Effect Of Acute Exercise On Skin Potential In Trained Athletes, Uğur Tarik Turaçlar, Sena Erdal, Abdullah Arslan, Ahmet Yildiz
Turkish Journal of Medical Sciences
Endosomatic electrodermal activity (skin potential level, skin potential response and latency) as an indirect indicator of sympathetic nervous system activity was measured in 22 trained athletes during resting and after acute exercise. The aim of this study was to investigate the difference in skin potential parameters in trained atheletes before and after acute exercise on a bicycle ergometer. Skin potential level (SPL) increased (p
A Novel Clinical And Laboratory Based Approach To Coronary Heart Disease: Relationship Between Angiography Findings, Antioxidant Enzymes And No, Bülent Sözmen, Fevzi̇ye Uysal, Dervi̇ş Gazi̇tepe, Leyla Aslan, Eser Yildirim Sözmen
A Novel Clinical And Laboratory Based Approach To Coronary Heart Disease: Relationship Between Angiography Findings, Antioxidant Enzymes And No, Bülent Sözmen, Fevzi̇ye Uysal, Dervi̇ş Gazi̇tepe, Leyla Aslan, Eser Yildirim Sözmen
Turkish Journal of Medical Sciences
Atherosclerosis is the most common manifestation of cardiovascular disease. However the exact mechanisms that take place in its pathogenesis have not yet been completely understood. Free radicals and lipid peroxidation may play an important role in the pathogenesis of atherosclerosis and endothelial dysfunction also may be an aggravating factor in this process. Unfortunately all of the previous studies have focused on the atherosclerotic tissue. Our aim was to establish a relationship between the antioxidant enzymes and plasma nitrate as an index of whole-body, endogenous nitric oxide production in coronary heart disease and also the relationship between these parameters and the …
Spontaneous Micronuclei In Cytokinesis-Blocked Bone Marrow And Peripheral Blood Iymphocytes Of Cml Patients, Di̇lek Koç Başer, Asuman Sunguroğlu, Işik Bökesoy, Akin Uysal
Spontaneous Micronuclei In Cytokinesis-Blocked Bone Marrow And Peripheral Blood Iymphocytes Of Cml Patients, Di̇lek Koç Başer, Asuman Sunguroğlu, Işik Bökesoy, Akin Uysal
Turkish Journal of Medical Sciences
Some genetic diseases may have increased cellular instability. Since chronic myloid leukemia (CML) has a genetic base, we aimed to seek the genetic instability of patients by micronucleus analysis, a mutation screening test which was applied by cytokinesis-blocked (CB) method. In this study, 10 CML patients at diagnosis, were analysed for their micronuclei (MN) frequencies. The values were evaluated in different culture conditions of blood and bone marrow cells. The results of CML patients are compared with control' MN values obtained by peripheral blood cultures induced with PHA. Between bone marrow and peripheral blood cultures MN values with or without …
Quantitative Histopathology In Superficial Bladder Tumors: The Value Of Mean Nuclear Size In Progression And Recurrence, Gülsüm Özlem Elpek, Teki̇nalp Gelen, Gülten Karpuzoğlu, Osman Saka
Quantitative Histopathology In Superficial Bladder Tumors: The Value Of Mean Nuclear Size In Progression And Recurrence, Gülsüm Özlem Elpek, Teki̇nalp Gelen, Gülten Karpuzoğlu, Osman Saka
Turkish Journal of Medical Sciences
The aim of this study was to evaluate the quanititation of the nuclear size of tumor cells in superficial bladder carcinomas in progression and recurrence. Thirty-four cases diagnosed primarily as superficial bladder carcinoma grade II without muscle invasion (Stage pTa and pT1) between 1986-1993 at the Department of Pathology of Akdeniz University Faculty of Medicine were analysed in three groups: 1- Ten cases without recurrent tumor. 2- Twelve cases with primary and recurrent superficial bladder tumor. 3- Twelve cases with superficial primary tumor and recurrent tumor with muscle invasion. The mean nuclear diameter of the tumor cells were obtained by …
Radioisotopic Evaluation Of Malignant Lung Tumors: A Technetium-99m-Methoxy-Isobutylisonitrile Study, Murathan Şahi̇n, Ayşenaz Özcan, İrem Bernay, Tarik Başoğlu, Ari̇f Engi̇n Demi̇rçali, Oğuz Uzun, Levent Erkan
Radioisotopic Evaluation Of Malignant Lung Tumors: A Technetium-99m-Methoxy-Isobutylisonitrile Study, Murathan Şahi̇n, Ayşenaz Özcan, İrem Bernay, Tarik Başoğlu, Ari̇f Engi̇n Demi̇rçali, Oğuz Uzun, Levent Erkan
Turkish Journal of Medical Sciences
Tumor imaging with myocardial perfusion agents has been a focal point for researchers. A kinetic study with 99m Technetium- methoxyisobutylisonitrile ( 99m Tc-MIBI) was performed to evaluate the tumor uptake of this radiopharmaceutical in lung cancer. Thirty-five patients with lung cancer were studied. In 21 (60%) patients, there were regions of high uptake of 99m Tc-MIBI in the lesions. Heart/tumor (H/T), heart/lung (H/L) and tumor/lung (T/L) ratios were obtained. H/T and H/L ratios were 1.66±0.22 and 2.10±0.28 in 2-3 min, and 1.69±0.25 and 2.14±0.27 in 29-30 min respectively. The T/L ratio was 1.28±0.10 in 2-3 min and 1.29±0.14 in 29-30 …
Urinary Serotonin And 5-Hydroxyindolacetic Acid Levels In Preeclampsia, Pervi̇n Vural, Cemi̇l Akgül, Mukaddes Canbaz, Alkan Yildirim
Urinary Serotonin And 5-Hydroxyindolacetic Acid Levels In Preeclampsia, Pervi̇n Vural, Cemi̇l Akgül, Mukaddes Canbaz, Alkan Yildirim
Turkish Journal of Medical Sciences
The role of serotonin in the pathogenesis of hypertension which is one of the main symptoms of preeclampsia is of growing importance. The levels of serotonin (5-Hydroxytryptamin or 5-HT) and its metabolite, 5-Hydroxyindolacetic acid (5-HIAA) in twenty-four hour urine samples taken from severe preeclamptic and normotensive pregnant women were determined by colon chromotography and spectrophotometry. In preeclamptic pregnant women there was a significant increase in 5-HT levels (P
Lupus Anticoagulant And Anticardiolipinantibodies In Unexplained Fetal Losses, Güli̇nnaz Alper, Ege Nazan Tavmergen, Yasemi̇n Kabasakal, Taner Onat
Lupus Anticoagulant And Anticardiolipinantibodies In Unexplained Fetal Losses, Güli̇nnaz Alper, Ege Nazan Tavmergen, Yasemi̇n Kabasakal, Taner Onat
Turkish Journal of Medical Sciences
Lupus anticoagulant (LA) and anti-cardiolipin antibodies (ACAs) are acquired antiphospholipid antibodies (APAs), which are considered to be important markers for pregnancy losses and intrauterine fetal demise. LA and ACAs have anticoagulant effects in vitro and thrombotic effects in vivo and are considered to be the cause of recur-rent pregnancy losses (RPLs), resulting from placental vascular thrombosis and infarction. The aim of this study was to identify the most sensitive and specific method of deter-mining APA positivity and to evaluate the prevalence of APA in patients with unex-plained RPL. The experiment consisted of 25 women with unexplained RPL, the patient group, …