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Articles 2131 - 2160 of 2205
Full-Text Articles in Medicine and Health Sciences
Tox And Detox: Are Teens' Smartphone Use And Non-Use Practices Fully Fungible?, Lelia Green, Debra Dudek, Lynne Cohen, Kjartan Ólafsson, Elisabeth Staksrud, Carmen Louise Jacques, Kelly Jaunzems
Tox And Detox: Are Teens' Smartphone Use And Non-Use Practices Fully Fungible?, Lelia Green, Debra Dudek, Lynne Cohen, Kjartan Ólafsson, Elisabeth Staksrud, Carmen Louise Jacques, Kelly Jaunzems
Research outputs 2022 to 2026
The public sphere includes a range of credible discourses asserting that a proportion of teenagers (“teens”) has an unhealthy dependence upon continuous connection with media devices, and especially smartphones. A review of media discourse (Jaunzems et al.) in Australia, and a critical review of public discourse in Australia and Belgium (Zaman et al.), reveal both positive and negative commentary around screentime. Despite the “emotionally laden, opposing views” expressed in the media, there appears to be a groundswell of concern around young people’s dependence upon digital devices (Zaman et al. 120). Concerns about ‘addiction’ to and dependency on digital media first …
Haemodiafiltration And Haemodialysis Should Be Reported Separately By Kidney Replacement Therapy Registries, Ulrich Steinwandel, Hugh Davies, Nicholas Gibson
Haemodiafiltration And Haemodialysis Should Be Reported Separately By Kidney Replacement Therapy Registries, Ulrich Steinwandel, Hugh Davies, Nicholas Gibson
Research outputs 2022 to 2026
No abstract provided.
Cannabinoid And Substance Relationships Of European Congenital Anomaly Patterns: A Space-Time Panel Regression And Causal Inferential Study, Albert Stuart Reece, Gary Kenneth Hulse
Cannabinoid And Substance Relationships Of European Congenital Anomaly Patterns: A Space-Time Panel Regression And Causal Inferential Study, Albert Stuart Reece, Gary Kenneth Hulse
Research outputs 2022 to 2026
With reports from Australia, Canada, USA, Hawaii and Colorado documenting a link between cannabis and congenital anomalies (CAs), this relationship was investigated in Europe. Data on 90 CAs were accessed from Eurocat. Tobacco and alcohol consumption and median household income data were from the World Bank. Amphetamine, cocaine and last month and daily use of cannabis from the European Monitoring Centre for Drugs and Drug Addiction. Cannabis herb and resin Δ9-Tetrahydrocannabinol concentrations were from published reports. Data were processed in R. Twelve thousand three hundred sixty CA rates were sourced across 16 nations of Europe. Nations with a higher or …
Why Do Men With Prostate Cancer Discontinue Active Surveillance For Definitive Treatment? A Mixed Methods Investigation, Megan Mcintosh, Melissa J. Opozda, Michael O’Callaghan, Andrew D. Vincent, Daniel A. Galvão, Camille E. Short
Why Do Men With Prostate Cancer Discontinue Active Surveillance For Definitive Treatment? A Mixed Methods Investigation, Megan Mcintosh, Melissa J. Opozda, Michael O’Callaghan, Andrew D. Vincent, Daniel A. Galvão, Camille E. Short
Research outputs 2022 to 2026
Objectives: To explore the personal and/or medical reasons patients on active surveillance (AS) have, or consider having, further definitive treatment for their prostate cancer. Research suggests up to 50% of patients on AS will discontinue within 5 years, though reasons for discontinuation from the patient's perspective is under-explored. Methods: Prostate cancer patients who were or had been on AS for at least 6 months were recruited. A questionnaire assessed reasons for receiving/considering definitive treatment and the extent to which reasons were personal or medical. Clinical information was extracted from a state-level population registry. A subset of participants were interviewed to …
Injury Surveillance In Community Cricket: A New Inning For South Africa, Benita Olivier, Oluchukwu L. Obiora, Candice Macmillan, Caroline Finch
Injury Surveillance In Community Cricket: A New Inning For South Africa, Benita Olivier, Oluchukwu L. Obiora, Candice Macmillan, Caroline Finch
Research outputs 2022 to 2026
Published injury rates amongst elite and club-level youth cricketers highlight the need to implement injury risk-reducing strategies amongst the youth cricketing population. Data from sports injury surveillance systems are a prerequisite for the development and evaluation of strategies to reduce injury risk. Therefore, collecting injury surveillance data is a positive move towards reducing injuries in cricket. In South Africa, a systematic, standardised, evidence-informed injury surveillance system currently does not exist for community levels of play, namely, in cricket-playing high schools and cricket clubs. Although injury surveillance systems exist at elite levels, the obvious differences in elite versus community cricket settings …
Comparison Of Auditory Steady-State Responses With Conventional Audiometry In Older Adults, Hadeel Y. Tarawneh, Hamid R. Sohrabi, Wilhelmina H. A. M. Mulders, Ralph N. Martins, Dona M. P. Jayakody
Comparison Of Auditory Steady-State Responses With Conventional Audiometry In Older Adults, Hadeel Y. Tarawneh, Hamid R. Sohrabi, Wilhelmina H. A. M. Mulders, Ralph N. Martins, Dona M. P. Jayakody
Research outputs 2022 to 2026
Behavioral measures, such as pure-tone audiometry (PTA), are commonly used to determine hearing thresholds, however, PTA does not always provide reliable hearing information in difficult to test individuals. Therefore, objective measures of hearing sensitivity that require little-to-no active participation from an individual are needed to facilitate the detection and treatment of hearing loss in difficult to test people. Investigation of the reliability of the auditory steady-state response (ASSR) for measuring hearing thresholds in older adults is limited. This study aimed to investigate if ASSR can be a reliable, objective measure of frequency specific hearing thresholds in older adults. Hearing thresholds …
Evaluation Of Virtual Screening Strategies For The Identification Of Γ-Secretase Inhibitors And Modulators, Alicia Ioppolo, Melissa Eccles, David Groth, Giuseppe Verdile, Mark Agostino
Evaluation Of Virtual Screening Strategies For The Identification Of Γ-Secretase Inhibitors And Modulators, Alicia Ioppolo, Melissa Eccles, David Groth, Giuseppe Verdile, Mark Agostino
Research outputs 2022 to 2026
γ-Secretase is an intramembrane aspartyl protease that is important in regulating normal cell physiology via cleavage of over 100 transmembrane proteins, including Amyloid Precursor Protein (APP) and Notch family receptors. However, aberrant proteolysis of substrates has implications in the progression of disease pathologies, including Alzheimer’s disease (AD), cancers, and skin disorders. While several γ-secretase inhibitors have been identified, there has been toxicity observed in clinical trials associated with non-selective enzyme inhibition. To address this, γ-secretase modulators have been identified and pursued as more selective agents. Recent structural evidence has provided an insight into how γ-secretase inhibitors and modulators are recognized …
European Epidemiological Patterns Of Cannabis- And Substance-Related Body Wall Congenital Anomalies: Geospatiotemporal And Causal Inferential Study, Albert Stuart Reece, Gary Kenneth Hulse
European Epidemiological Patterns Of Cannabis- And Substance-Related Body Wall Congenital Anomalies: Geospatiotemporal And Causal Inferential Study, Albert Stuart Reece, Gary Kenneth Hulse
Research outputs 2022 to 2026
As body wall congenital anomalies (BWCAs) have a long history of being associated with prenatal or community cannabis exposure (CCE), it was of interest to investigate these epidemiological relationships in Europe given the recent increases in cannabis use prevalence, daily intensity, and Δ9-tetrahydrocannabinol (THC) potency. Methods: This study makes use of BWCA data from Eurocat, drug exposure data from the European Monitoring Centre for Drugs and Drug Addiction, and income from the World Bank. Results: The mapping analysis showed that BWCARs increased in France, Spain, and the Netherlands. The bivariate mapping analysis showed that the BWCA rates (BWCAR) and the …
Sulfur Compounds: From Plants To Humans And Their Role In Chronic Disease Prevention, Caroline R. Hill, Armaghan Shafaei, Lois Balmer, Joshua R. Lewis, Jonathan M. Hodgson, A. Harvey Millar, Lauren C. Blekkenhorst
Sulfur Compounds: From Plants To Humans And Their Role In Chronic Disease Prevention, Caroline R. Hill, Armaghan Shafaei, Lois Balmer, Joshua R. Lewis, Jonathan M. Hodgson, A. Harvey Millar, Lauren C. Blekkenhorst
Research outputs 2022 to 2026
Sulfur is essential for the health of plants and is an indispensable dietary component for human health and disease prevention. Its incorporation into our food supply is heavily reliant upon the uptake of sulfur into plant tissue and our subsequent intake. Dietary requirements for sulfur are largely calculated based upon requirements for the sulfur-containing amino acids (SAA), cysteine and methionine, to meet the demands for synthesis of proteins, enzymes, co-enzymes, vitamins, and hormones. SAA are found in abundance in animal sources and are relatively low in plants. However, some plants, particularly cruciferous and allium vegetables, produce many protective sulfur-containing secondary …
Sibling Concordance In Symptom Onset And Atrophy Growth Rates In Stargardt Disease Using Ultra-Widefield Fundus Autofluorescence, Rachael C. Heath Jeffery, Jennifer A. Thompson, Johnny Lo, Tina M. Lamey, Terri L. Mclaren, John N. De Roach, Dimitar N. Azamanov, Ian L. Mcallister, Ian J. Constable, Fred K. Chen
Sibling Concordance In Symptom Onset And Atrophy Growth Rates In Stargardt Disease Using Ultra-Widefield Fundus Autofluorescence, Rachael C. Heath Jeffery, Jennifer A. Thompson, Johnny Lo, Tina M. Lamey, Terri L. Mclaren, John N. De Roach, Dimitar N. Azamanov, Ian L. Mcallister, Ian J. Constable, Fred K. Chen
Research outputs 2022 to 2026
Purpose: To investigate concordance in symptom onset, area of dark autofluorescence (DAF), and growth rate (GR) between Stargardt disease siblings at an age-matched time point. Methods: In this retrospective longitudinal study of sibling pairs with identical biallelic ABCA4 variants, age at symptom onset, best-corrected visual acuity, atrophy area, and effective radius of DAF on ultra-widefield fundus autofluorescence were recorded. Absolute intersibling differences for both eyes were compared with absolute interocular differences using the Mann-Whitney test. Results: Overall 39 patients from 19 families were recruited. In 16 families, age-matched best-corrected visual acuity and DAF were compared between siblings. In 8 families, …
Sedentary Behaviour, Physical Activity, And Their Associations With Health Outcomes At The Time Of Diagnosis In People With Inoperable Lung Cancer, Shu Ning Ch’Ng, Joanne A. Mcveigh, David Manners, Terry Boyle, Carolyn J. Peddle-Mcintyre, Rajesh Thomas, Jeanie Leong, Samantha Bowyer, Kirsten Mooney, Leon Straker, Daniel A. Galvão, Vinicius Cavalheri
Sedentary Behaviour, Physical Activity, And Their Associations With Health Outcomes At The Time Of Diagnosis In People With Inoperable Lung Cancer, Shu Ning Ch’Ng, Joanne A. Mcveigh, David Manners, Terry Boyle, Carolyn J. Peddle-Mcintyre, Rajesh Thomas, Jeanie Leong, Samantha Bowyer, Kirsten Mooney, Leon Straker, Daniel A. Galvão, Vinicius Cavalheri
Research outputs 2022 to 2026
This study aimed to examine sedentary behaviour (SB), physical activity (PA) and their associations with health-related measures at the time of diagnosis in people with inoperable lung cancer. People newly diagnosed with inoperable lung cancer were invited to participate in the study and asked to wear an accelerometer for seven consecutive days. Variables analysed included time spent in SB, light intensity PA (LIPA) and moderate-to-vigorous intensity PA (MVPA). Daily steps were also recorded. Data on symptoms, health-related quality of life (HRQoL), hand grip force, comorbidities and lung function were collected. Of the 120 patients referred to the study, 89 (74 …
Rapid Triage For Ischemic Stroke: A Machine Learning-Driven Approach In The Context Of Predictive, Preventive And Personalised Medicine, Yulu Zheng, Zheng Guo, Yanbo Zhang, Jianjing Shang, Leilei Yu, Ping Fu, Yizhi Liu, Xingang Li, Hao Wang, Ling Ren, Wei Zhang, Haifeng Hou, Xuerui Tan, Wei Wang, Global Health Epidemiology Reference Group (Gherg)
Rapid Triage For Ischemic Stroke: A Machine Learning-Driven Approach In The Context Of Predictive, Preventive And Personalised Medicine, Yulu Zheng, Zheng Guo, Yanbo Zhang, Jianjing Shang, Leilei Yu, Ping Fu, Yizhi Liu, Xingang Li, Hao Wang, Ling Ren, Wei Zhang, Haifeng Hou, Xuerui Tan, Wei Wang, Global Health Epidemiology Reference Group (Gherg)
Research outputs 2022 to 2026
Background
Recognising the early signs of ischemic stroke (IS) in emergency settings has been challenging. Machine learning (ML), a robust tool for predictive, preventive and personalised medicine (PPPM/3PM), presents a possible solution for this issue and produces accurate predictions for real-time data processing.
Methods
This investigation evaluated 4999 IS patients among a total of 10,476 adults included in the initial dataset, and 1076 IS subjects among 3935 participants in the external validation dataset. Six ML-based models for the prediction of IS were trained on the initial dataset of 10,476 participants (split participants into a training set [80%] and an internal …
A Scoping Review Of Non-Pharmacological Health Education Provided To Families Of Children With Idiopathic Childhood Constipation Within Primary Health Care, Davina Houghton, Diana Arabiat, Deborah Ireson, Evalotte Mörelius
A Scoping Review Of Non-Pharmacological Health Education Provided To Families Of Children With Idiopathic Childhood Constipation Within Primary Health Care, Davina Houghton, Diana Arabiat, Deborah Ireson, Evalotte Mörelius
Research outputs 2022 to 2026
Objectives: Idiopathic childhood constipation is a prevalent condition that initially brings the child under the care of the primary health care team. Although it is acknowledged that health education is crucial to reducing chronicity, the range of evidenced-based non-pharmacological health education provided to families has not previously been reviewed. For this scoping review, 4 research questions sought to identify papers that provide information on the utilization of guidelines, the range of health education, who provides it, and whether any gaps exist. Methods: Following a registered protocol and using the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping …
Mother's Own Milk Compared With Formula Milk For Feeding Preterm Or Low Birth Weight Infants: Systematic Review And Meta-Analysis, Natalie A. Strobel, Claire Adams, Daniel R. Mcaullay, Karen M. Edmond
Mother's Own Milk Compared With Formula Milk For Feeding Preterm Or Low Birth Weight Infants: Systematic Review And Meta-Analysis, Natalie A. Strobel, Claire Adams, Daniel R. Mcaullay, Karen M. Edmond
Research outputs 2022 to 2026
Objectives: We assessed the effect of feeding preterm or low birth weight infants with infant formula compared with mother's own milk on mortality, morbidity, growth, neurodevelopment, and disability. Methods: We searched Medline (Ovid), Embase (Ovid), and Cochrane Central Register of Controlled Studies to October 1, 2021. Results: Forty-two studies enrolling 89 638 infants fulfilled the inclusion criteria. We did not find evidence of an effect on mortality (odds ratio [OR] 1.26, 95% confidence interval [CI] 0.91-1.76), infection (OR 1.52, 95% CI 0.98-2.37), cognitive neurodevelopment (standardized mean difference -1.30, 95% CI -3.53 to 0.93), or on growth parameters. Formula milk feeding …
Plasma P-Tau181/Aβ1-42 Ratio Predicts Aβ-Pet Status And Correlates With Csf-P-Tau181/Aβ1-42 And Future Cognitive Decline, Christopher J. Fowler, Erik Stoops, Stephanie R. Rainey-Smith, Eugeen Vanmechelen, Jeroen Vanbrabant, Nele Dewit, Kimberley Mauroo, Paul Maruff, Christopher C. Rowe, Jurgen Fripp, Qiao-Xin Li, Pierrick Bourgeat, Steven J. Collins, Ralph N. Martins, Colin L. Masters, James D. Doecke
Plasma P-Tau181/Aβ1-42 Ratio Predicts Aβ-Pet Status And Correlates With Csf-P-Tau181/Aβ1-42 And Future Cognitive Decline, Christopher J. Fowler, Erik Stoops, Stephanie R. Rainey-Smith, Eugeen Vanmechelen, Jeroen Vanbrabant, Nele Dewit, Kimberley Mauroo, Paul Maruff, Christopher C. Rowe, Jurgen Fripp, Qiao-Xin Li, Pierrick Bourgeat, Steven J. Collins, Ralph N. Martins, Colin L. Masters, James D. Doecke
Research outputs 2022 to 2026
Background: In Alzheimer's disease (AD), plasma amyloid beta (Aβ)1-42 and phosphorylated tau (p-tau) predict high amyloid status from Aβ positron emission tomography (PET); however, the extent to which combination of these plasma assays can predict remains unknown. Methods: Prototype Simoa assays were used to measure plasma samples from participants who were either cognitively normal (CN) or had mild cognitive impairment (MCI)/AD in the Australian Imaging, Biomarkers and Lifestyle (AIBL) study. Results: The p-tau181/Aβ1-42 ratio showed the best prediction of Aβ-PET across all participants (area under the curve [AUC] = 0.905, 95% confidence interval [CI]: 0.86–0.95) and in CN (AUC = …
An Il1rl1 Genetic Variant Lowers Soluble St2 Levels And The Risk Effects Of Apoe-Ε4 In Female Patients With Alzheimer’S Disease, Yuanbing Jiang, Xiaopu Zhou, Hiu Yi Wong, Li Ouyang, Fanny C. F. Ip, Vicky M. N. Chau, Shun-Fat Lau, Wei Wu, Daniel Y. K. Wong, Heukjin Seo, Wing-Yu Fu, Nicole C. H. Lai, Yuewen Chen, Yu Chen, Estella P.S. Tong, Alzheimer’S Disease Neuroimaging Initiative, Vincent C. T. Mok, Timothy C. Y. Kwok, Kin Y. Mok, Maryam Shoai, Benoit Lehallier, Patricia Morán Losada, Eleanor O'Brien, Tenielle Porter, Simon Laws, John Hardy, Tony Wyss-Coray, Colin L. Masters, Amy K.Y. Fu, Nancy Y. Ip
An Il1rl1 Genetic Variant Lowers Soluble St2 Levels And The Risk Effects Of Apoe-Ε4 In Female Patients With Alzheimer’S Disease, Yuanbing Jiang, Xiaopu Zhou, Hiu Yi Wong, Li Ouyang, Fanny C. F. Ip, Vicky M. N. Chau, Shun-Fat Lau, Wei Wu, Daniel Y. K. Wong, Heukjin Seo, Wing-Yu Fu, Nicole C. H. Lai, Yuewen Chen, Yu Chen, Estella P.S. Tong, Alzheimer’S Disease Neuroimaging Initiative, Vincent C. T. Mok, Timothy C. Y. Kwok, Kin Y. Mok, Maryam Shoai, Benoit Lehallier, Patricia Morán Losada, Eleanor O'Brien, Tenielle Porter, Simon Laws, John Hardy, Tony Wyss-Coray, Colin L. Masters, Amy K.Y. Fu, Nancy Y. Ip
Research outputs 2022 to 2026
Changes in the levels of circulating proteins are associated with Alzheimer’s disease (AD), whereas their pathogenic roles in AD are unclear. Here, we identified soluble ST2 (sST2), a decoy receptor of interleukin-33–ST2 signaling, as a new disease-causing factor in AD. Increased circulating sST2 level is associated with more severe pathological changes in female individuals with AD. Genome-wide association analysis and CRISPR–Cas9 genome editing identified rs1921622, a genetic variant in an enhancer element of IL1RL1, which downregulates gene and protein levels of sST2. Mendelian randomization analysis using genetic variants, including rs1921622, demonstrated that decreased sST2 levels lower AD …
What Are The Benefits And Challenges Of Mentoring In Midwifery? An Integrative Review, Krystyl Wissemann, Dianne Bloxsome, Annemarie De Leo, Sara Bayes
What Are The Benefits And Challenges Of Mentoring In Midwifery? An Integrative Review, Krystyl Wissemann, Dianne Bloxsome, Annemarie De Leo, Sara Bayes
Research outputs 2022 to 2026
Aim: The aim of this review was to synthesize best available evidence on mentoring programmes for midwives who have worked within the clinical setting for more than 1 year. Background: Lack of job satisfaction, stress, burnout and limited managerial support contributes to midwifery workforce attrition and the ongoing global shortage of midwives. Mentoring may be one way to improve staff retention, leading to positive clinical and organizational outcomes. Design: A five-step integrative review approach, based on a series of articles published by the Joanna Briggs Institute for conducting systematic reviews, was used to develop a search strategy, selection criteria, method …
Provision Of Non-Invasive Coronary And Carotid Vascular Imaging Results On Changes In Diet And Physical Activity In Asymptomatic Adults: A Scoping Review, Simone Radavelli Bagatini, Abadi K. Gebre, Mary A. Kennedy, Marc Sim, Lauren C. Blekkenhorst, Catherine P. Bondonno, Ben Jackson, James Dimmock, Marcus P. Schlaich, Jonathan M. Hodgson, Joshua R. Lewis
Provision Of Non-Invasive Coronary And Carotid Vascular Imaging Results On Changes In Diet And Physical Activity In Asymptomatic Adults: A Scoping Review, Simone Radavelli Bagatini, Abadi K. Gebre, Mary A. Kennedy, Marc Sim, Lauren C. Blekkenhorst, Catherine P. Bondonno, Ben Jackson, James Dimmock, Marcus P. Schlaich, Jonathan M. Hodgson, Joshua R. Lewis
Research outputs 2022 to 2026
Background: Although a healthy diet and physical activity have been shown to prevent or delay cardiovascular disease (CVD) hospitalizations and deaths, most adults do not meet current guidelines. Provision of coronary artery calcification (CAC) and carotid ultrasound (CUS) imaging results may motivate beneficial lifestyle changes. We scoped the existing literature for studies providing non-invasive vascular imaging results and reporting diet, physical activity, and/or anthropometric measures to identify knowledge gaps and opportunities for further research. Methods: A systematic search was performed across three electronic databases, in line with PRISMA ScR guidelines and Arksey and O'Malley's scoping review framework. Results: Twenty studies …
Perspectives On Wider Integration Of The Health-Assistive Smart Home, Gordana Dermody, Jenna Mikus, Davina Porock, Dov Sugarman, Naeem K. Janjua, Christopher How, Roschelle Fritz
Perspectives On Wider Integration Of The Health-Assistive Smart Home, Gordana Dermody, Jenna Mikus, Davina Porock, Dov Sugarman, Naeem K. Janjua, Christopher How, Roschelle Fritz
Research outputs 2022 to 2026
Most older adults desire to be as independent as possible and remain living in their ancestral home as they age. Aging-in-place maximizes the independence of older adults, enhancing their wellbeing and quality of life while decreasing the financial burden of residential care costs. However, due to chronic disease, multimorbidity, and age-related changes, appropriate conditions are required to make aging-in-place possible. Remote monitoring with smart home technologies could provide the infrastructure that enables older adults to remain living independently in their own homes safely. The health-assistive smart home shows great promise, but there are challenges to integrating smart homes on a …
Characterisation Of Lung Function Trajectories And Associated Early-Life Predictors In An Australian Birth Cohort Study, Francesca Sanna, Francesca Locatelli, Peter D. Sly, Elisha White, Jane Heyworth, Graham L. Hall, Rachel E. Foong, David Blake
Characterisation Of Lung Function Trajectories And Associated Early-Life Predictors In An Australian Birth Cohort Study, Francesca Sanna, Francesca Locatelli, Peter D. Sly, Elisha White, Jane Heyworth, Graham L. Hall, Rachel E. Foong, David Blake
Research outputs 2022 to 2026
Background There is growing evidence that lung function in early-life predicts later lung function. Adverse events over the lifespan might influence an individual’s lung function trajectory, resulting in poor respiratory health. The aim of this study is to identify early-life risk factors and their impact on lung function trajectories to prevent long-term lung impairments. Methods Our study included participants from the Raine Study, a prospective pregnancy cohort, with at least two spirometry measurements. Lung function trajectories from the 6-to 22-year follow-ups were characterised using finite mixture modelling. Multinomial logistic regression analyses were used to evaluate the association between early-life predictors …
Evidence For Global Health Care Interventions For Preterm Or Low Birth Weight Infants: An Overview Of Systematic Reviews, Karen Edmond, Natalie Strobel
Evidence For Global Health Care Interventions For Preterm Or Low Birth Weight Infants: An Overview Of Systematic Reviews, Karen Edmond, Natalie Strobel
Research outputs 2022 to 2026
Contex: Twenty-four research questions (framed as population, intervention, comparator, and outcomes) for global health care interventions for preterm and low birth weight (LBW) infants were identified at a World Health Organization guideline development group expert meeting in December 2020. Objective: To describe which systematic reviews had addressed these research questions in the last 3 years. Data sources: Medline (Ovid); the Cochrane Database of Systematic Reviews; the Cochrane Database of Systematic Review Protocols; and the PROSPERO International prospective register of systematic reviews databases from January 1, 2019 to December 31, 2021 were used.Randomized controlled trials or observational studies. Two reviewers independently …
The Impact Of Skeletal Muscle Disuse On Distinct Echo Intensity Bands: A Retrospective Analysis, Zachary S. Logeson, Rob J. Maclennan, Gerard Kyle B. Abad, Johnathon M. Methven, Molly R. Gradl, Matheus D. Pinto, Ronei S. Pinto, Matt S. Stock
The Impact Of Skeletal Muscle Disuse On Distinct Echo Intensity Bands: A Retrospective Analysis, Zachary S. Logeson, Rob J. Maclennan, Gerard Kyle B. Abad, Johnathon M. Methven, Molly R. Gradl, Matheus D. Pinto, Ronei S. Pinto, Matt S. Stock
Research outputs 2022 to 2026
Echo intensity (EI) is a novel tool for assessing muscle quality. EI has traditionally been reported as the mean of the pixel histogram, with 0 and 255 arbitrary units (A.U.) representing excellent and poor muscle quality, respectively. Recent work conducted in youth and younger and older adults suggested that analyzing specific EI bands, rather than the mean, may provide unique insights into the effectiveness of exercise and rehabilitation interventions. As our previous work showed deterioration of muscle quality after knee joint immobilization, we sought to investigate whether the increase in EI following disuse was limited to specific EI bands. Thirteen …
A Review Of Arthritis Diagnosis Techniques In Artificial Intelligence Era: Current Trends And Research Challenges, Maleeha Imtiaz, Syed Afaq Ali Shah, Zia Ur Rehman
A Review Of Arthritis Diagnosis Techniques In Artificial Intelligence Era: Current Trends And Research Challenges, Maleeha Imtiaz, Syed Afaq Ali Shah, Zia Ur Rehman
Research outputs 2022 to 2026
Deep learning, a branch of artificial intelligence, has achieved unprecedented performance in several domains including medicine to assist with efficient diagnosis of diseases, prediction of disease progression and pre-screening step for physicians. Due to its significant breakthroughs, deep learning is now being used for the diagnosis of arthritis, which is a chronic disease affecting young to aged population. This paper provides a survey of recent and the most representative deep learning techniques (published between 2018 to 2020) for the diagnosis of osteoarthritis and rheumatoid arthritis. The paper also reviews traditional machine learning methods (published 2015 onward) and their application for …
A Large-Scale Genome-Wide Cross-Trait Analysis Reveals Shared Genetic Architecture Between Alzheimer’S Disease And Gastrointestinal Tract Disorders, Emmanuel O. Adewuyi, Eleanor K. O'Brien, Dale R. Nyholt, Tenielle Porter, Simon Laws
A Large-Scale Genome-Wide Cross-Trait Analysis Reveals Shared Genetic Architecture Between Alzheimer’S Disease And Gastrointestinal Tract Disorders, Emmanuel O. Adewuyi, Eleanor K. O'Brien, Dale R. Nyholt, Tenielle Porter, Simon Laws
Research outputs 2022 to 2026
Consistent with the concept of the gut-brain phenomenon, observational studies suggest a relationship between Alzheimer’s disease (AD) and gastrointestinal tract (GIT) disorders; however, their underlying mechanisms remain unclear. Here, we analyse several genome-wide association studies (GWAS) summary statistics (N = 34,652–456,327), to assess the relationship of AD with GIT disorders. Findings reveal a positive significant genetic overlap and correlation between AD and gastroesophageal reflux disease (GERD), peptic ulcer disease (PUD), gastritis-duodenitis, irritable bowel syndrome and diverticulosis, but not inflammatory bowel disease. Cross-trait meta-analysis identifies several loci (Pmeta-analysis < 5 × 10−8) shared by AD and GIT disorders (GERD and PUD) including …
Exercise Recommendations For People With Bone Metastases: Expert Consensus For Healthcare Providers And Clinical Exercise Professionals, Kristin L. Campbell, Prue Cormie, Sarah Weller, Shabbir M. H. Alibhai, Kate A. Bolam, Anna Campbell, Andrea L. Cheville, Mary-Ann Dalzell, Nicolas H. Hart, Celestia S. Higano, Kirstin Lane, Sami Mansfield, Margaret L. Mcneely, Robert U. Newton, Morten Quist, Jennifer Rauw, Friederike Rosenberger, Daniel Santa Mina, Kathryn H. Schmitz, Kerri M. Winters-Stone, Joachim Wiskemann, Jennifer Goulart
Exercise Recommendations For People With Bone Metastases: Expert Consensus For Healthcare Providers And Clinical Exercise Professionals, Kristin L. Campbell, Prue Cormie, Sarah Weller, Shabbir M. H. Alibhai, Kate A. Bolam, Anna Campbell, Andrea L. Cheville, Mary-Ann Dalzell, Nicolas H. Hart, Celestia S. Higano, Kirstin Lane, Sami Mansfield, Margaret L. Mcneely, Robert U. Newton, Morten Quist, Jennifer Rauw, Friederike Rosenberger, Daniel Santa Mina, Kathryn H. Schmitz, Kerri M. Winters-Stone, Joachim Wiskemann, Jennifer Goulart
Research outputs 2022 to 2026
Purpose: Exercise has been underutilized in people with advanced or incurable cancer despite the potential to improve physical function and reduce psychosocial morbidity, especially for people with bone metastases because of concerns over skeletal complications. The International Bone Metastases Exercise Working Group (IBMEWG) was formed to develop best practice recommendations for exercise programming for people with bone metastases on the basis of published research, clinical experience, and expert opinion. Methods: The IBMEWG undertook sequential steps to inform the recommendations: (1) modified Delphi survey, (2) systematic review, (3) cross-sectional survey to physicians and nurse practitioners, (4) in-person meeting of IBMEWG to …
Assessment And Monitoring Of Achilles Tendinopathy In Clinical Practice: A Qualitative Descriptive Exploration Of The Barriers Clinicians Face, Myles Calder Murphy, James Debenham, Caroline Bulsara, Paola Chivers, Ebonie Kendra Rio, Sean Docking, Mervyn Travers, William Gibson
Assessment And Monitoring Of Achilles Tendinopathy In Clinical Practice: A Qualitative Descriptive Exploration Of The Barriers Clinicians Face, Myles Calder Murphy, James Debenham, Caroline Bulsara, Paola Chivers, Ebonie Kendra Rio, Sean Docking, Mervyn Travers, William Gibson
Research outputs 2022 to 2026
Our primary objective was to explore the barriers preventing clinicians from implementing what they think is ideal practice as it relates to using tools to aid diagnosis and monitor progress in mid-portion Achilles tendinopathy. Our secondary objectives were to describe the assessments employed by clinicians in their own practice to aid with (a) diagnosis and (b) monitoring progress in Achilles tendinopathy and explore the outcome measure domains clinicians believe to be the most and least important when managing patients with Achilles tendinopathy. We employed a qualitative descriptive study design. Thirteen participants (eight female, five male) from across Australia, consisting of …
Covid-19 Restrictions And Psychological Well-Being Of Fathers With Infants Admitted To Nicu—An Exploratory Cross-Sectional Study, Esther Abena Adama, Flora Koliouli, Livio Provenzi, Nancy Feeley, Edwin Van Teijlingen, Jillian Ireland, Frances Thomson-Salo, Minesh Khashu, Finesse Group
Covid-19 Restrictions And Psychological Well-Being Of Fathers With Infants Admitted To Nicu—An Exploratory Cross-Sectional Study, Esther Abena Adama, Flora Koliouli, Livio Provenzi, Nancy Feeley, Edwin Van Teijlingen, Jillian Ireland, Frances Thomson-Salo, Minesh Khashu, Finesse Group
Research outputs 2022 to 2026
Aim
To describe the impact of the COVID-19 restrictions on the caregiving activities and psychological well-being of fathers with infants admitted to neonatal units.
Methods
Cross-sectional study using adapted COPE-IS and COPE-IU tools. Participants' recruitment occurred online via social media and parents' associations. Online survey in English, French and Italian were distributed and promoted via websites and social media platforms of parent's associations. The study was undertaken across 12 countries in Asia, Australia, Africa and Europe.
Results
A total of 108 fathers of NICU infants completed the survey. COVID-19 related restrictions were categorised into 3 types: no restrictions, partial and …
Associations Of Specific Types Of Fruit And Vegetables With Perceived Stress In Adults: The Ausdiab Study, Simone Radavelli-Bagatini, Marc Sim, Lauren C. Blekkenhorst, Nicola P. Bondonno, Catherine P. Bondonno, Richard Woodman, Joanne M. Dickson, Dianna J. Magliano, Jonathan E. Shaw, Robin M. Daly, Jonathan M. Hodgson, Joshua R. Lewis
Associations Of Specific Types Of Fruit And Vegetables With Perceived Stress In Adults: The Ausdiab Study, Simone Radavelli-Bagatini, Marc Sim, Lauren C. Blekkenhorst, Nicola P. Bondonno, Catherine P. Bondonno, Richard Woodman, Joanne M. Dickson, Dianna J. Magliano, Jonathan E. Shaw, Robin M. Daly, Jonathan M. Hodgson, Joshua R. Lewis
Research outputs 2022 to 2026
Purpose:
Higher total fruit and vegetable (FV) intakes have been associated with lower perceived stress. The relationship between specific types of FV and perceived stress remains uncertain. The aims of this cross-sectional study were to explore the relationship between consumption of specific types of FV with perceived stress in a population-based cohort of men and women aged ≥ 25 years from the Australian Diabetes, Obesity and Lifestyle (AusDiab) Study.
Methods:
Dietary intake was assessed using a validated Food Frequency Questionnaire (n = 8,640). Perceived stress was evaluated using a validated Perceived Stress Questionnaire, with values ranging 0–1 (lowest to highest). …
Development, Implementation, And Evaluation Of A Professional Practice Model: A Scoping Review, Gemma Doleman, Di Twigg
Development, Implementation, And Evaluation Of A Professional Practice Model: A Scoping Review, Gemma Doleman, Di Twigg
Research outputs 2022 to 2026
Aim:
The aim of this study is to synthesize available literature describing the development, implementation and evaluation of a Professional Practice Model.
Background:
A Professional Practice Model is an overarching theory-based framework that depicts nursing values and defines the structure and process of nursing care. No research has synthesized available literature on this topic in recent times. Evaluation: A review of English language papers was published from 2015 to 2022. Fourteen studies met the inclusion criteria.
Key Issues:
All studies highlighted the importance of having a Professional Practice Model that reflects nursing care activities and resonates with nurses across an …
Developing, Monitoring, And Reporting Of Fidelity In Aphasia Trials: Core Recommendations From The Collaboration Of Aphasia Trialists (Cats) Trials For Aphasia Panel, Nicholas Behn, Madeleine Harrison, Marian C. Brady, Caterina Breitenstein, Marcella Carragher, Julius Fridriksson, Erin Godecke, Argye Hillis, Helen Kelly, Rebecca Palmer, Miranda L. Rose, Shirley Thomas, Donna Tippett, Linda Worrall, Frank Becker, Katerina Hilari
Developing, Monitoring, And Reporting Of Fidelity In Aphasia Trials: Core Recommendations From The Collaboration Of Aphasia Trialists (Cats) Trials For Aphasia Panel, Nicholas Behn, Madeleine Harrison, Marian C. Brady, Caterina Breitenstein, Marcella Carragher, Julius Fridriksson, Erin Godecke, Argye Hillis, Helen Kelly, Rebecca Palmer, Miranda L. Rose, Shirley Thomas, Donna Tippett, Linda Worrall, Frank Becker, Katerina Hilari
Research outputs 2022 to 2026
Background:
Developing, monitoring, and reporting of fidelity are essential and integral components to the design of randomised controlled trials (RCTs) in stroke and aphasia. Treatment fidelity refers to the degree to which an intervention is delivered as intended and is directly related to the quality of the evidence generated by RCTs. Clear documentation of treatment fidelity in trials assists in the evaluation of the clinical implications of potential benefits attributed to the intervention. Consideration of the implementation requirements of a research-based intervention as intended in a clinical context is necessary to achieve similar outcomes for a clinical population. Despite this, …