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Aflatoxin Contamination Of Commercial Maize Products During An Outbreak Of Acute Aflatoxicosis In Eastern And Central Kenya, Karen E. Gieseker, Lauren Lewis, Mary Onsongo, Henry Njapau, Helen Schurz Rogers, George Luber, Stephanie Kieszak, Jack Nyamongo, Lorraine Backer, Abdikher Mohamud Dahiye, Ambrose Misore, Kevin Decock, Carol Rubin, Kenya Aflatoxicosis Investigation Group
Aflatoxin Contamination Of Commercial Maize Products During An Outbreak Of Acute Aflatoxicosis In Eastern And Central Kenya, Karen E. Gieseker, Lauren Lewis, Mary Onsongo, Henry Njapau, Helen Schurz Rogers, George Luber, Stephanie Kieszak, Jack Nyamongo, Lorraine Backer, Abdikher Mohamud Dahiye, Ambrose Misore, Kevin Decock, Carol Rubin, Kenya Aflatoxicosis Investigation Group
Public Health Faculty Publications
n April 2004, one of the largest aflatoxicosis outbreaks occurred in rural Kenya, resulting in 317 cases and 125 deaths. Aflatoxin-contaminated homegrown maize was the source of the outbreak, but the extent of regional contamination and status of maize in commercial markets (market maize) were unknown. We conducted a cross-sectional survey to assess the extent of market maize contamination and evaluate the relationship between market maize aflatoxin and the aflatoxicosis outbreak. We surveyed 65 markets and 243 maize vendors and collected 350 maize products in the most affected districts. Fifty-five percent of maize products had aflatoxin levels greater than the …
Case-Control Study Of An Acute Aflatoxicosis Outbreak, Kenya, 2004, Karen E. Gieseker, Eduardo Azziz-Baumgartner, Kimberly Lindblade, Helen Schurz Rogers, Stephanie Kieszak, Henry Njapau, Rosemary Schleicher, Leslie F. Mccoy, Ambrose Misore, Kevin Decock, Carol Rubin, Lawrence Slutsker, Aflatoxin Investigative Group
Case-Control Study Of An Acute Aflatoxicosis Outbreak, Kenya, 2004, Karen E. Gieseker, Eduardo Azziz-Baumgartner, Kimberly Lindblade, Helen Schurz Rogers, Stephanie Kieszak, Henry Njapau, Rosemary Schleicher, Leslie F. Mccoy, Ambrose Misore, Kevin Decock, Carol Rubin, Lawrence Slutsker, Aflatoxin Investigative Group
Public Health Faculty Publications
OBJECTIVES: During January-June 2004, an aflatoxicosis outbreak in eastern Kenya resulted in 317 cases and 125 deaths. We conducted a case-control study to identify risk factors for contamination of implicated maize and, for the first time, quantitated biomarkers associated with acute aflatoxicosis.
DESIGN: We administered questionnaires regarding maize storage and consumption and obtained maize and blood samples from participants.
PARTICIPANTS: We recruited 40 case-patients with aflatoxicosis and 80 randomly selected controls to participate in this study.
EVALUATIONS/MEASUREMENTS: We analyzed maize for total aflatoxins and serum for aflatoxin B1-lysine albumin adducts and hepatitis B surface antigen. We used regression and survival …