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Full-Text Articles in Medicine and Health Sciences
The Potential Weight Loss Benefits Of Tirzepatide: A Double-Edged Sword?, Muhammad Taha Nasim, Ayesha Ali, Muhammad Tabish Nasim
The Potential Weight Loss Benefits Of Tirzepatide: A Double-Edged Sword?, Muhammad Taha Nasim, Ayesha Ali, Muhammad Tabish Nasim
Medical College Documents
No abstract provided.
Association Of Vaspin Levels And Its Snp Rs2236242 With Sestational Diabetes At A Tertiary Care Setting, Karishma Kanhya Lal, Rabail Jarwar, Sabah Farhat, Syeda Sadia Fatima
Association Of Vaspin Levels And Its Snp Rs2236242 With Sestational Diabetes At A Tertiary Care Setting, Karishma Kanhya Lal, Rabail Jarwar, Sabah Farhat, Syeda Sadia Fatima
Medical College Documents
Objectives:
To evaluate and correlate vaspin levels and genotype frequency in gestational diabetes mellitus.
Methods:
The case-control study was conducted at Aga Khan University, Karachi, from November 2015 to December 2016, and comprised pregnant women in their second trimester with gestational diabetes mellitus. Healthy pregnant women with similar characteristics were enrolled as the control group. Tetra arms amplification system for vaspin gene was performed. SPSS 21 was used for data analysis.
Results:
Of the 112 pregnant women, 67(60%) were normo-glycaemic and 45(40%) had gestational diabetes. Those with gestational diabetes had a higher body mass index (p=0.047) and fasting blood glucose …
Euglycemic Diabetic Ketoacidosis In A 27 Year-Old Female Patient With Type-1-Diabetes Treated With Sodium-Glucose Cotransporter-2 (Sglt2) Inhibitor Canagliflozin, Nimrah Bader, Lubna Mirza
Euglycemic Diabetic Ketoacidosis In A 27 Year-Old Female Patient With Type-1-Diabetes Treated With Sodium-Glucose Cotransporter-2 (Sglt2) Inhibitor Canagliflozin, Nimrah Bader, Lubna Mirza
Medical College Documents
We are reporting a timely case of atypical euglycemic diabetic ketoacidosis in a type 1 diabetic patient treated with sodium-glucose cotransporter-2 (SGLT-2) inhibitor canagliflozin. The clinical history, physical examination findings and laboratory values are described. Other causes of acidosis such as salicylate toxicity or alcohol intoxication were excluded. Ketoacidosis resolved after increasing dextrose and insulin doses supporting the hypothesis that SGLT-2 inhibitors may lead to hypoinsulinemia. Euglycemic ketoacidosis did not recur in our patient after discontinuing canagliflozin. We recommend reserving SGLT2 inhibitor therapy to type 2 diabetics, discontinuing medication and treating patients presenting with ketoacidosis due to SGLT-2 inhibitors with …