Medicine and Health Sciences Commons^™

The Effects Of Cued Speech On Phonemic Awareness Skills, Jessica M. Phillips

Masters Theses

Research suggests phonemic awareness is enhanced through multimodality training. Cued Speech is a multimodality system that combines hand signs with mouth movements to represent phonemes of the spoken language. This system has been utilized successfully in developing phonological awareness with children with hearing loss. However, no research is available on its effectiveness with children who are not deaf or hard-of-hearing. The efficacy of the use of Cued Speech for the enhancement of phonological skills in typically developing 1st grade students was evaluated in this study. Twenty-six 1^st graders identified as low-achieving readers by their classroom teachers were administered the …

Can Consumers Perceive A Difference In Quality When Comparing Whole-Grain Gluten-Free Baked Goods To Refined Gluten-Free Baked Goods At Varying Flour Levels, Jenna R. Carlson

Masters Theses

The prevalence of celiac disease and gluten intolerances has increased drastically in the last few decades, accounting for 1 in 100 individuals, or about 1% of Americans (Mager, Qiao, & Turner, 2012). The only treatment for celiac disease or any other gluten intolerance is the gluten-free diet. The gluten-free diet can lack many essential nutrients. The purpose of this research was to identify if consumers could perceive a difference in quality when comparing whole-grain gluten-free baked goods to refined gluten-free baked goods at varying flour levels of 20%, 50%, and 100%.

The researcher-developed Carlson Acceptability of Gluten-Free Baked Goods Survey …

An Exploration Of College Student Experiences Regarding Healthy Eating At A Midsized Midwestern University: A Qualitative Approach, E. Jordan Stayer

Masters Theses

This study was an exploration of the experiences college students have while eating in on-campus dining centers at a midsized, Midwest, public university. The present study examined college students' (n = 7) experiences of eating in the dining centers with a campus meal plan. Participants were asked a series of questions regarding their individual beliefs, their surrounding environment, and their physical behaviors while dining.

The study concluded that dining habits are very personal to each and every human being in the world. At the higher education level, because each student brings with them a completely different taste, desire, and …

The Nutrient Intake Of Homeless Women Of Grand Rapids, Michigan, Emily D. Popma-Metsaars

Masters Theses

Background Homeless individuals comprise about 1% of the American population with 1/3 of this particular population being women. And despite the potential for hunger, the homeless population has a similar prevalence of overweight/obese as other Americans. The Heartside neighborhood of Grand Rapids is a very low-income area of the city, inhabited by the poor and homeless. The Food Access in Michigan Project is studying the relationship between food insecurity and food environments in Michigan.

Objectives The purpose of this study was to determine the characteristics of the diet of homeless women in Heartside. This study examined the level of food …

Effects Of Fatty Acid Structure On Endothelial Cell Expression Of Connexin43, Albert E. Sowers Iii

Masters Theses

The epidemic of obesity-related metabolic and cardiovascular diseases is linked to elevated fatty acids (FA). Epidemiological data argue that trans FA contribute to the development and progression of these disease processes. Previous work suggests the similarity in structure between saturated and trans FA may stimulate inflammation through trans FA interactions with toll-like receptor 4 (TLR4). To evaluate the impact of trans FA on cardiovascular health, the response of endothelial cells to trans FA was evaluated. Specifically, responses to the 18-carbon trans FA elaidic acid (EA) were compared to the same length cis FA oleic acid (OA). Endothelial cells were exposed …

Generation And Use Of Monoclonal Antibodies To Ldentify Subpopulations Of Post Thaw Stallion Sperm, Sarah Abdulaziz Almuhanna

Masters Theses

Artificial insemination (AI) is commonly used for breeding of horses. Selecting high quality semen is critical to AI success but is difficult to achieve. In this study, we investigate the potential of generating antibodies against stallion sperm to identify subpopulations of post-thaw sperm based on surface markers. Female Balb/C mice are immunized with semen from a 24-year-old fertile stallion followed by booster immunizations each week for at least six weeks. Monoclonal antibodies are generated by fusion of myeloma cells to mouse spleen cells. Eight monoclonal antibodies resulting from these fusions are subdivided into four immunostaining patterns. These patterns differentially recognize …

I Get By With A Little Help From My Friends: A Qualitative Study Of Nurse Close Work Friendship And Social Support, Jennifer Ptacek

Masters Theses

The nursing profession is laden with numerous job, emotional labor, and communication stressors, which come from both patients and healthcare organizations. These frequent and simultaneous pressures can result in nurse burnout and turnover (Tracy, 2009). Socially supportive workplace communication has been identified as a solution to reducing nurse stress, burnout, and turnover (Apker & Ray, 2003), but has not specifically considered social support in nurse work friendships. A mixed qualitative method study was conducted with five nurse best friend pairs, using job observations of participants’ work friendship communication and individual and joint interviews. Two major communication themes emerged from the …

The Efficacy Of Music As A Non-Analgesic Method Of Reducing Pain Perception During Cold Pressor Trials, Amanda Lynn Ziemba

Masters Theses

The purpose of this project was to investigate the impact of differentiated onset of self-selected music on pain perception and pain tolerance during a cold pressor test. Subjects participated in four trials during which music was presented at different points of time in relation to their exposure to the cold pressor test. Results indicated that listening to music prior to and concurrently with the onset of the pain resulted in lower self-reported pain (F(3, 66) :3.25, p < .05). Behavioral results indicated that subjects were able to tolerate an average of 25s longer (F(2.04,44.81): I.56,p > .05.) when music was presented after the onset of painful stimuli. Both results have positive implications for the clinical use of music as …

Gpu-Accelerated Influenza Simulations For Operational Modeling, Peter Holvenstot

Masters Theses

Simulations of influenza spread are useful for decision-making during public-health emergencies. Policy-makers use models to predict disease spread and estimate the effects of various intervention strategies. Effective modeling of targeted intervention strategies requires accurate modeling of individual-level behavior and transmission. However, this greatly increases the computational costs of these agent-based models. In addition, if the models are used as an outbreak progresses, some operational decisions must occur rapidly in order to contain the spread of the disease.

Graphics Processing Units (GPUs) are a type of specialized processor used to drive graphical displays. Many recent devices also allow users to write …

Effects Of Various Partial Body Cooling Techniques On Core Temperature During Recovery From Prolonged Cycling-Induced Heat Stress, Afton Danielle Seeley

Masters Theses

The purpose of this study was to investigate the effects of using an ice-vest and a palm cooling device on core and skin temperatures, heart rate, and perceived thermal comfort during a one hour recovery period following exercise in the heat. Ten recreationally active adults cycled for one hour at 50% V0₂ peak on a cycle ergometer while exposed to 36°C 45%relative humidity environmental conditions. Following exercise, each subjectwas exposed to an ice vest, a palm cooling device, or a non cooling control while seated in the environmental chamber for 60 more minutes. No significant differencewas found betweenany of …

The Nucleic Acid Binding Properties Of The Pwi Motif, Hamideh Keshavarz-Mohammadian

Masters Theses

The PWI motif is a highly conserved domain that contains a Proline-Tryptophan-Isoleucine (PWI) tripeptide sequence, for which it is named. Proteins that contain a PWI motif are known to be involved in the constitutive and alternative splicing and the 3'-end processing of messenger RNA transcripts. The hypothesized role of the PWI motif is to nonspecifically interact with nucleic acids. The PWI motif is capable of binding both doublestranded and single stranded forms of DNA and RNA. The structure of the highly conserved core of the PWI motif reveals that it adopts a four-helix bundle fold. The structured core domain, however, …

The Effects Of Different Warm-Up Methods On Anaerobic Power, Bradley Kendall

Masters Theses

The purpose of this study was to investigate the effects of various warm-up methods on Wingate Anaerobic Test (WAnT) performance. The goal of this study was to investigate how a general cycling warm-up, a dynamic stretching routine, a static stretching routine, and the combination of both static stretching followed by cycling and dynamic stretching followed by cycling affect WAnT performance. Ten recreationally active subjects (5 males, 5 females), completed five WAnT on a Monark Ergomedic 984E cycle separated by at least 48 hours. Subjects were randomly assigned to an order of conditions and performed a different condition prior to each …

Comparison Of Dual- And Tri-Axial Accelerometer Accuracy, Lindsay Powell Toth

Masters Theses

The purpose of this study was to investigate the accuracy of the Omron HJ-720ITC and the Fitbit Zip activity monitors with regard to step count, energy expenditure, and distance traveled measurements. The importance of this research rests in the success rates of pedometer-based physical activity interventions which have been shown to increase physical activity while also enabling weight loss and lowering blood pressure in the adult population. Activity monitors available for retail sale must be found accurate for proper participation in exercise interventions especially low-cost devices as used in this study.

In order to test the accuracy of the Omron …

Combined Effects Of Mdma And Ethanol On Locomotor Activity And Place Conditioning In Male And Female Adolescent Sprague-Dawley Rats, Keli A. Herr

Masters Theses

MDMA, ("Ecstasy") is commonly abused in combination with ethanol (EtOH). Relatively few preclinical studies have investigated sex differences in animal models of polysubstance use. The current study employed a conditioned place preference (CPP) procedure to assess the behavioral effects of the co-administration ofMDMA /EtOH in 32 male and 32 female adolescent Sprague-Dawley rats. Following a 15 min habituation trial, eight 30-min conditioning trials were conducted in two- compartment chambers with different environmental cues. Before each drug conditioning trials, rats were administered intraperitoneal (i.p.) injections of MDMA(6.6 mg/kg), EtOH (1.5 g/kg), MDMA (6.6 mg/kg) and EtOH (1.5 g/kg), or saline. Prior …

The Relationship Between Speaking Rate And Nasalance In Typical Adult Speakers, Rachel Whitney

Masters Theses

Nasometry is a non-invasive tool frequently used to measure speech resonance in clinical populations. The instrument uses an acoustic recording system to derive a measure termed nasalance, which is an estimate of the relative amount of acoustic energy emitted from the nasal cavity. Nasometry protocols do not provide detailed instructions for speaking rate control during data collection. Studies attempting to establish a relationship between speaking rate and nasalance have yielded mixed results; therefore, it is important to identify the influence of speaking rate on nasalance in a variety of speaking tasks. If rate is found to influence nasalance values, protocols …

Vaccinia Virus Flll Mediated Expedition Of Tanapoxvirus Replication In Cell Culture, Yih Wen Goh

Masters Theses

Tanapoxvirus (TPV) produces large but slow-forming plaques as opposed to vaccinia virus (VACV) that forms similar large plaques but more rapidly. A number of genes were identified in VACV, inclucding FllL, A33R, A34R and A36R that contribute to the regulation of virus release and dissemination, and are particularly responsible for the induction of actin tails. Among them, TPV lacks homologs of the FllL and A36R genes. F11Lmediated inhibition of RhoA-mDia signaling was shown to enhance the microtubules dynamics and modulates the cortical actin that assisted in the release of progeny virus from infected cells. To understand the possible effects of …

Selling Life To Abortion-Seekers: A Content Analysis Of Passive And Active Persuasion In Crisis Pregnancy Center Marketing, Alexander Kocman

Masters Theses

For supporters of the pro-life cause, crisis pregnancy centers (or CPC's) have become the "darlings of the movement," according to the New York Times (Belluck, 2013), offering women with unplanned pregnancies free advice, information, classes, childcare, and needed supplies. For abortion advocates, such establishments are intended to seduce vulnerable abortion-seekers into a situation where they will be counseled out of an abortion and possibly even proselytized. Yet for as much controversy as exists in the news media, medical community, and legal realm about CPC's, there is an unsettling lack of understanding of how--and why--CPC's market themselves the way they do. …

The Long-Term Effects Of An Aac Communication Partner Training Program, Brooke Capp

Masters Theses

The current investigation was a follow-up study to a research project conducted in summer 2012 by Fanale. The Fanale (2012) study looked at the effectiveness of parent training on parents' perspectives of AAC, as well as parents' use of specific communication facilitating strategies. The follow-up maintenance study investigated long-term effects of training on parent perceptions' and use of communication facilitating strategies. Through this project parents received additional training and different levels of support over four months in order to enhance the parents' abilities to utilize AAC in other environments, activities, and communication partners, as well as gather information on parents' …

Comparison Of Two Dark Chocolate And Their Effect On Blood Pressure, Melissa A. Foor

Masters Theses

This study was designed to determine if dark chocolate helps lower blood pressure and if the concentration of the dark chocolate varies the result. Currently, one in four Americans has high blood pressure. The recommended treatment may include medicine or a diet referred to as DASH or Dietary Approaches to Stop Hypertension. This study followed a within-subjects design having all participants receive each type of dark chocolate. Twenty-seven participants started the study to measure their blood pressure while consuming dark chocolate for a week at a time. Results showed that Hershey's Special Dark Chocolate did not lower blood pressure significantly …

Substance Abuse In Older Adults: An Exploratory Study, Rachael Hawn

Masters Theses

The increasing number of older adults in the United States, due in part to the Baby Boomer generation, means that there is also an increase in the number of older adults dealing with substance abuse problems. The compounded effects of multiple legal medications with alcohol, illicit drugs, or abused prescription drugs on the withdrawal process are likely to make delineating between legitimate medication side effects and withdrawal symptoms incredibly difficult for medical professionals working with older adults. With the average older adult legally using 17 medications from nine different medical professionals, the physical effects of substance abuse might easily go …

Differences In Mental Health Treatment Recommendations For Older And Younger Adults, Michelle M. Smith

Masters Theses

Failure to meet geriatric mental health needs is increasingly problematic. Research indicates that the problem is not simply a matter of insufficient numbers of mental health practitioners (MHPs), but also ageist attitudes and lack of knowledge about and training with older adults. The current study reviews the literature regarding knowledge about older people, education and training that mental health professionals receive, and the attitudes that are held by mental health professionals. The study also assessed for differences in treatment recommendations that MHP made for older versus younger clients, investigated whether MHP knowledge about the mental health of older adults, attitudes …

Pre-Meal To-Go Boxes: Implications For Portion Control, Margaret J. Schuster

Masters Theses

Title: Pre-Meal To-Go Boxes: Implications for Portion Control

Authors: M. J. Schuster, BS; T. L. Brooks, PhD, RD; J.E. Painter, PhD, RD; C. Honselman, PhD, RD

Introduction: Obesity rates are increasing and seem to be correlated with increasing portion sizes of restaurant meals because of consumer desire for value. The purpose of this study was to determine if using a pre-meal to-go box has an impact on customers' total food intake of a restaurant meal.

Methods: Subjects were a convenience sample of adults (n=49) at a spaghetti dinner. Subjects were randomly assigned to receive approximately 18 ounces of spaghetti and …

Cervical Cancer Histology Image Feature Extraction And Classification, Peng Guo

Masters Theses

"Cervical cancer, the second most common cancer affecting women worldwide and the most common in developing countries can be cured if detected early and treated. Expert pathologists routinely visually examine histology slides for cervix tissue abnormality assessment. In previous research, an automated, localized, fusion-based approach was investigated for classifying squamous epithelium into Normal, CIN1, CIN2, and CIN3 grades of cervical intraepithelial neoplasia (CIN) based on image analysis of 62 digitized histology images obtained through the National Library of Medicine. In this research, CIN grade assessments from two pathologists are analyzed and are used to facilitate atypical cell concentration feature development …

The Effects Of Music Instruction On Phonological Awareness In Children With Hearing Impairment, Chelsea Fitch

Masters Theses

Phonological awareness skills are essential for reading development. Children with hearing loss lack access to essential auditory information that allows development of phonological awareness (Dillon, John, & Pisoni, 2011). Music instruction is becoming a popular approach to teach reading for typically developing children, and studies have supported beneficial effects from this treatment methodology. However, there is limited research regarding the use of music to teach phonological awareness and reading skills to children with hearing impairment (Gromko, 2005).

The effectiveness of a music program on increasing phonological awareness skills in children who are deaf or hard-of-hearing was evaluated in this study. …

Increasing Cooking And Nutritional Knowledge Of Food Pantry Clients Via Cookbook Intervention, Joshua Kleczynski

Masters Theses

This study was designed to assess eating habits, cooking habits, and nutritional knowledge of food pantry clients. As a whole, the average American consumes a less-than-optimal intake of nutrients. This, combined with the elevated national food insecurity rate of 14.5%, produces an advantageous situation to educate food pantry clients about healthy lifestyle practice through cooking. This study utilized a quasi-experimental design including a pre-assessment, intervention, post-assessment design. Forty-nine participants were included in study, and either received a cookbook (intervention group) or were a control subject and only completed surveys. Results revealed that the cookbook intervention did not elicit any behavior …

The Effects Of A Moisture-Wicking Fabric Shirt On The Physiological Responses During Acute Exercise In The Heat, Kimberly Wigboldy

Masters Theses

The purpose of this study is to investigate the effects that a form fitted, moisture-wicking fabric shirt, promoted to have improved evaporative and ventilation properties, has on the thermoregulatory, physiological and perceptual response during moderate intensity exercise in the heat for an extended duration of exercise of 90 minutes. Ten healthy subjects (7 males, 3 females), completed two heat stress tests consisting of 20 minute seated rest in a neutral environment (24°C, 60% RH), 30 minute seated rest in a hot environment (33°C, 60% RH), and 90 minutes of exercise(50% V0_{2 peak}) on a magnetically-braked cycle ergometerin a …

Use Of A Specific Alpha7 Nicotinic Acetylcholine Receptor Agonist Can Prevent Loss Of Retinal Ganglion Cells In An In Vivo Rat Glaucoma Model, David Mata

Masters Theses

Acetylcholine (ACh) has been shown to have a neuroprotective effect against glutamate-induced excitotoxicity in cultured retinal ganglion cells (RGCs) through activation of α7 nicotinic ACh receptors (nAChRs). In this study, the neuroprotective effects of the α7 nAChR agonist, PNU-282987, were investigated using an in vivo model of glaucoma in adult Long Evans rats. Hypertonic saline injections were used to induce a glaucoma model. After one month, retinas were removed, flat mounted, fixed and labeled with an antibody against Thy 1.1 to label RGCs and fluorescently tagged for visualization. Eye drop application of PNU-282987 resulted in neuroprotection against RGC loss in …

Expression Of The Chemokine Receptor, Cxcr4, And Its Ligand, Sdf-1, Are Increased In Purkinje Cells Of The Multiple System Atrophy Cerebellum, Megan Welter

Masters Theses

Multiple System Atrophy (MSA) is a sporadic, neurodegenerative disease that consists of three conditions: autonomic dysfunction, Parkinsonism and cerebellar ataxia. Our lab conducted an Affymetrix global gene expression analysis using pons tissue of MSA patients to determine genes that are differentially expressed when compared to non- MSA controls. This study identified upregulated genes, including the C-X-C chemokine receptor type 4, CXCR4, to which stromal cell-derived factor-I (SDF-1) is the natural ligand. The CXCR4/SDF-1 signaling pair has been sho.wn to play multiple roles in the brain, such as inducing neuronal apoptosis and promoting leukocyte recruitment during inflammation. The MSA cerebellum presents …

Executive Functions And Social Interactions: Developing Social Scenarios, Mackenzie Waite

Masters Theses

The aim of this study was to develop a series of vignettes to form the basis for an assessment of executive functions (EFs) for 9 – 12 year old children. Although EFs are necessary for effective social communication and positive social interactions, currently, most EF assessments focus on impersonal activities. Little research exists that incorporates real-time processing using ecologically valid social scenarios. The current study aims to develop realistic scenarios that children could encounter in daily life. Ethnographic interviews were conducted with six participants, who worked in a school with 9-12 year old children, to gain their perspective on social …

Explicit Teacher-Implemented Phoneme Awareness Instruction: Preschool Effects, Heather M. Osterhouse

Masters Theses

The purpose of the current study was to investigate the impact of explicit, concentrated, teacher-implemented phonological awareness instruction for ―at risk‖ 4- year-olds. Early childhood educators were trained to implement a 10-week program delivered for 20-minute sessions, four times a week, in their classrooms. The program focused on phonological awareness beginning at the level of letter-sound knowledge and advancing to blending and segmenting constituent phonemes in words. Pre- to post-treatment comparisons of phonological awareness and letter knowledge skills indicated that children in the experimental group made significant gains in comparison to the control group in phoneme blending and letter knowledge. …