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Articles 151 - 180 of 1807
Full-Text Articles in Medicine and Health Sciences
Effect Of Image Sharpening On Radiographic Image Quality, Jefferson Lee Clark
Effect Of Image Sharpening On Radiographic Image Quality, Jefferson Lee Clark
Loma Linda University Electronic Theses, Dissertations & Projects
There is evidence that capture and processing of the digital radiographic images may contain artifacts that could reduce the diagnostic value of dental radiographs. This phenomenon has been reported through various case reports. However, its effect on radiographic image quality has not been studied. The purpose of this study is to evaluate the effect of image processing on the quality of dental digital radiographs using the most common type of filter; sharpening. Four imaging modalities (2 CMOS, 1 PSP, 1 conventional film) were used to radiograph a DDQA imaging phantom (Digital Dental Quality Assurance phantom) and to create a flat …
Living On Borrowed Time: A Longitudinal Examination Of A Time-Limited Housing Voucher Program, Lauren D. Foster
Living On Borrowed Time: A Longitudinal Examination Of A Time-Limited Housing Voucher Program, Lauren D. Foster
Loma Linda University Electronic Theses, Dissertations & Projects
There are a number of families currently living in poverty across the United States (Census, 2010). These families are often stressed and spread thin in their daily lives. Different governmental supports are used to bolster individuals and families during their experiences of poverty. One such entity is the United States Department of Housing and Urban Affairs (HUD). This agency provides housing to countless residents each year (HUD, 2016). Much is known about the different program that HUD offers but information is limited what strengths families can bring in that can aid in their experiences while living in poverty. Using Hierarchical …
Predictors Of Postpartum Depression Among Women In Karachi, Pakistan, Vimla Gill John
Predictors Of Postpartum Depression Among Women In Karachi, Pakistan, Vimla Gill John
Loma Linda University Electronic Theses, Dissertations & Projects
Pakistan has the highest prevalence of postpartum depression (PPD) among Asian countries. The purpose of this quantitative, cross-sectional study was to determine the predictors of PPD among women in Karachi, Pakistan. The Transactional Model of Stress and Coping was used as a framework. A purposive convenience sample of 234 postpartum women was taken from out-patient departments of a tertiary care hospital in Karachi, Pakistan. A survey in English and Urdu containing the Edinburgh Postnatal Depression Scale (EPDS), DUREL Religion Index Subscale three, Cohen’s 10-item Perceived Stress Scale (PSS), Multidimensional Scale of Perceived Social Support (MSPSS), Abuse Assessment Screen, Traditional postpartum …
Clinicians’ Perspectives On Adopting A Lung Cancer Palliative Care Intervention, Shaunna Siler
Clinicians’ Perspectives On Adopting A Lung Cancer Palliative Care Intervention, Shaunna Siler
Loma Linda University Electronic Theses, Dissertations & Projects
Despite the significant progress in implementing palliative care interventions for cancer patients, few intervention studies seek healthcare clinicians’ input prior to implementation. The purpose of this research was then to explore palliative care and oncology clinicians’ (e.g., physicians, nurses, social workers, and chaplains) perspectives on current challenges and useful practices in meeting the quality of life needs of lung cancer patients and family caregivers, and to increase the likelihood of the adoption of a palliative care intervention based on understanding current trends in palliative care delivery at three outpatient oncology sites. The conceptual framework used for this study was the …
Coping As A Mediator Between Symptom Burden And Distress In Lung Cancer Patients, Spring F. Gehring
Coping As A Mediator Between Symptom Burden And Distress In Lung Cancer Patients, Spring F. Gehring
Loma Linda University Electronic Theses, Dissertations & Projects
Lung cancer is considered the leading cause of cancer death worldwide. An estimated 224,390 new cases of lung cancer are expected to be diagnosed and 158,080 Americans are expected to die from lung cancer in 2016 (National Institutes of Health, 2016; Siegel, Miller, & Jemal, 2016). Lung cancer patients also report the highest levels of psychological distress and symptom burden than any other forms of cancer (Linden, Vodermaier, MacKenzie, & Greig, 2012). Given the prevalence and impact of lung cancer, it is imperative to address the emotional toll this diagnosis can have on those suffering with the disease to develop …
A Novel Population Of Cardiovascular Progenitors Persist In Neonates As Mesendodermal Cells, Julia Kim
A Novel Population Of Cardiovascular Progenitors Persist In Neonates As Mesendodermal Cells, Julia Kim
Loma Linda University Electronic Theses, Dissertations & Projects
The rise in mortality due to cardiovascular disease has increased the need to develop an efficient regenerative therapeutic for heart failure. Numerous cell-based therapies have been investigated for myocardial regeneration; however, an optimal progenitor has yet to be discovered. Identifying a resident cell population with enhanced ability to differentiate into multiple lineages would greatly contribute to the field of stem cell-based regenerative therapy. Evidence suggests that endogenous cardiovascular progenitor cells (CPCs) that have been isolated from the heart itself express ISL1, KDR, and MESP1, and are capable of differentiating into all major cardiac lineages. The earlier developmental stage at which …
Dyadic Research In Couple Therapy: The Link Between Attachment And Relationship Satisfaction, Bryson Greaves
Dyadic Research In Couple Therapy: The Link Between Attachment And Relationship Satisfaction, Bryson Greaves
Loma Linda University Electronic Theses, Dissertations & Projects
Couple therapy ranks among the most frequently and diligently researched topics in Marital and Family therapy (MFT). Additionally, intimate partner relationships are a key focal point for clinical intervention with increasingly more couples seeking therapy to address relational conflict, repair emotional injury, and increase intimacy (Lebow, Chambers, Christensen, & Johnson 2012). Rigorous empirical inquiry has suggested that attachment theory is a crucial foundation to understanding relationship distress and increasing relationship satisfaction (Wiebe & Johnson, 2016). Secure attachment between intimate partners can lead to an increase in trust (Pistole, 1993), healthy emotion regulation (Kobak & Hazan, 1991), and positive conflict resolution …
Relationship Between Vestibular System, Vision, Anxiety, And Chronic Motion Sensitivity, Ahmad A. Alharbi
Relationship Between Vestibular System, Vision, Anxiety, And Chronic Motion Sensitivity, Ahmad A. Alharbi
Loma Linda University Electronic Theses, Dissertations & Projects
BACKGROUND: Chronic motion sensitivity (CMS) has been defined as a feeling of un-wellness elicited by either actual or perceived motion. CMS is a common condition and is more prevalent in females than in males. In addition to a variety of symptoms, young adults with CMS have less postural stability than those without CMS. OBJECTIVE: To determine whether vestibular system integrity, dependence on visual cues for postural stability, and the anxiety level are different between young adults with and without CMS, and whether it differs by gender within each group. METHODS: Sixty young adults (30 females and 30 males) were assigned …
Cancer Center Regional Benchmarks For Psychosocial Care, Desiree R. Azizoddin
Cancer Center Regional Benchmarks For Psychosocial Care, Desiree R. Azizoddin
Loma Linda University Electronic Theses, Dissertations & Projects
The American College of Surgeons (ACoS) Commissions on Cancer (CoC) formulated and implemented standard 3.2 for Psychosocial Distress Screening. This standard requires that all accredited cancer centers evaluate psychosocial distress and provide appropriate triage and intervention for all cancer patients. Over the past decade, Loma Linda University Medical Oncology Center (LLUMOC) administration, physicians, nurses, psychosocial care staff, and chaplaincy collaborated to implement a psychosocial screening and referral program throughout cancer patient services. This current research includes qualitative analysis assessing strengths and barriers of the psychosocial program at LLUMOC from the perspective of LLUMOC providers and two directors of Supportive Care …
The Lived Experience Of Retention And Progression Of Black/African American Nursing Students, India Mylon Medley
The Lived Experience Of Retention And Progression Of Black/African American Nursing Students, India Mylon Medley
Loma Linda University Electronic Theses, Dissertations & Projects
Despite recent strides to increase workforce diversity, nurses continue to inadequately reflect the ethnic composition of the population they serve. To effectively answer the national calls for increased diversity in the nursing workforce, there must be a greater representation of minority students studying nursing. However, minority nursing students, especially those of Black/African American descent, have less access to nursing education, poorer retention and progression rates in nursing programs, and are more likely to withdraw from programs. The existence of an increasingly diverse nursing workforce depends upon the recruitment, retention, progression, and graduation of minority students. Whereas Historically Black Colleges and …
Prenatal Undernutrition, Metyrapone, And The Cerebrovasculature, Lara Durrant
Prenatal Undernutrition, Metyrapone, And The Cerebrovasculature, Lara Durrant
Loma Linda University Electronic Theses, Dissertations & Projects
The link between intrauterine environmental conditions and adult cardiovascular system is well established. Independent of lifestyle factors such as poor diet and exercise habits, individuals who have been exposed to stressful conditions in utero show an increased risk of health problems such as hypertension, stroke, and type II diabetes. In support of the Fetal Origin of Adult Disease hypothesis, many labs have reported permanent anatomical and physiological changes associated with fetal stress and nutrient deficiency, with a focus on organ systems such as the kidney and heart. One key idea proposed by many of these studies is the glucocorticoid hypothesis, …
Targeting Ledgf/P75 To Sensitize Chemoresistant Prostate Cancer Cells To Taxanes, Leslimar Rios-Colón
Targeting Ledgf/P75 To Sensitize Chemoresistant Prostate Cancer Cells To Taxanes, Leslimar Rios-Colón
Loma Linda University Electronic Theses, Dissertations & Projects
Prostate cancer (PCa) is the second most diagnosed cancer in males. This disease disproportionately affects African American men, with a higher incidence and mortality compared to other ethnic/racial groups. An aging male population and the complexity of addressing the health disparities associated with this disease puts PCa into the spotlight due to its serious public health implications and the imminent fiscal challenge over the next decades. Chronic prostate inflammation resulting in activation of stress and prosurvival pathways contribute to disease progression and the development of chemoresistance. Lens epithelium-derived growth factor p75 (LEDGF/p75) is a stressresponse protein that promotes cellular survival …
Pas Signaling Mechanisms In Aer And Aer2, Darysbel Garcia
Pas Signaling Mechanisms In Aer And Aer2, Darysbel Garcia
Loma Linda University Electronic Theses, Dissertations & Projects
PAS domains are widespread signal sensors that share a conserved three-dimensional αβ fold that consists of a central β-sheet flanked by several α- helices. The aerotaxis receptor Aer from Escherichia coli and the Aer2 chemoreceptor from Pseudomonas aeruginosa both contain PAS domains. Aer senses oxygen (O2) indirectly via an FAD cofactor bound to its PAS domain, while Aer2 directly binds O2 to its PAS b-type heme cofactor. The Aer and Aer2 PAS domains both interact with a signal transduction domain known as a HAMP domain. The PAS-HAMP arrangement differs between Aer and Aer2, with Aer- PAS residing adjacent to its …
Organizational, Nurse, And Patient Empowerment At A Magnet And Non-Magnet Hospital, Mai Yaseen
Organizational, Nurse, And Patient Empowerment At A Magnet And Non-Magnet Hospital, Mai Yaseen
Loma Linda University Electronic Theses, Dissertations & Projects
Purpose/Aims: To explore the relationships between organizational, nurse, and patient empowerment at a Magnet designated hospital versus a non-Magnet designated hospital. There are three aims to the study. Aim 1 examines the relationship between level of organizational empowerment and individual nurse self-empowerment (Self-efficacy). Aim 2 examines the relationship between individual nurse self-empowerment and patient empowerment. Aim 3 investigates if there are any differences in empowerment levels between a Magnet and non-Magnet designated hospital. Background: Patients must feel empowered to make decisions and participate in their care however; it is the healthcare provider’s role to prepare patients to make these decisions. …
Marriage And Family Therapy And The Law: Discovering Systemic Common Ground, Jason C. Richards
Marriage And Family Therapy And The Law: Discovering Systemic Common Ground, Jason C. Richards
Loma Linda University Electronic Theses, Dissertations & Projects
Many important decisions regarding couples and families are made by the legal system. However, this system’s adversarial nature often results in relational losses for clients, even when one “wins” a case. Some believe a solution may exist in legally-minded marriage and family therapists, who, as experts in family systems theory, are in a unique position to help facilitate healing in a flawed, but well-meaning family court system (Brooks & Madden, 2012; Madden, 2008). However, the literature reveals that new therapists may lack appropriate legal knowledge when they graduate, suggesting a need for different preparation by marriage and family therapy programs …
Anti-Tumor Mechanisms Of Hpv16 E6*, Whitney S. Evans
Anti-Tumor Mechanisms Of Hpv16 E6*, Whitney S. Evans
Loma Linda University Electronic Theses, Dissertations & Projects
High-risk types of the human papillomavirus (HR-HPV) are the causative agents of nearly all cases of cervical cancer, as well as a significant number of head, neck, penile, vulvar and anal cancers. Like many other viruses with small genomes, HPV (~8 kb) utilizes numerous mechanisms to increase the capacity of its genome to encode the proteins necessary for successful completion of its infectious life cycle, including alternative splicing. Studies over the past few decades have focused intensively on the activities and roles of E6 proteins from HR-HPVs during the process of cellular transformation, clearly implicating E6 as a major transforming …
Accuracy Of Implants Placed With Surgical Guides: Thermoplastic Vs. 3-D Printed, Caitlyn K. Bell
Accuracy Of Implants Placed With Surgical Guides: Thermoplastic Vs. 3-D Printed, Caitlyn K. Bell
Loma Linda University Electronic Theses, Dissertations & Projects
Purpose: The purpose of this study was to evaluate the accuracy of placed implants using two different guided implant surgery materials: thermoplastic vs. 3-D printed surgical guides. Materials and Methods:Twenty duplicate mandibular models, ten thermoplastic and ten 3-D printed surgical guides were used. Twenty implants were placed following the guided surgery protocol. Cone beam computed tomography scans of placed implants and the control implant were superimposed to measure deviations. Results: The thermoplastic group showed average deviations of 3.4 degrees, 1.3mm at the head, and 1.6mm at the apex of the implant compared to 2.36 degrees, 0.51mm, and …
Effect Of Heavy Lifting With A Head Strap On The Pelvic Floor Across The Menstrual Cycle, Yvonne Biswokarma
Effect Of Heavy Lifting With A Head Strap On The Pelvic Floor Across The Menstrual Cycle, Yvonne Biswokarma
Loma Linda University Electronic Theses, Dissertations & Projects
Background: Pelvic organ prolapse (POP) occurs in 10% of women in Nepal, even 6% of nulliparous women have symptomatic POP.1 This may be linked to the heavy lifting tasks performed by women using a head strap.2 This study explored the impact of hormonal changes on the pelvic floor when performing these tasks during each phase of the menstrual cycle. Methods: The study included 22 female Nepali participants with a mean age of 27.4(3.6) years; all were from rural villages and frequently carried with a head strap. Using intravaginal pressure transducers (IVT), the mean change in intraabdominal pressure (IAP) was found …
Neuroprotective Molecules And Strategies In A Rat Model Of Neonatal Hypoxic Ischemic Encephalopathy, Brandon Joseph Dixon
Neuroprotective Molecules And Strategies In A Rat Model Of Neonatal Hypoxic Ischemic Encephalopathy, Brandon Joseph Dixon
Loma Linda University Electronic Theses, Dissertations & Projects
Neonatal hypoxic ischemic encephalopathy (HIE) is a devastating disease that primarily causes neuronal and white matter injury and is among the leading cause of death among infants. Currently there are no well-established treatments; thus, it is important to understand the pathophysiology of the disease and elucidate complications that are creating a gap between basic science and clinical translation. In the development of neuroprotective strategies and translation of experimental results in HIE, there are many limitations and challenges to master based on an appropriate study design, drug delivery properties, dosage, and use in neonates. Since there are no established therapies for …
Comparison Of Two Methods Of Transpalatal Arch And Lingual Arch Activation, Taoran Zhang
Comparison Of Two Methods Of Transpalatal Arch And Lingual Arch Activation, Taoran Zhang
Loma Linda University Electronic Theses, Dissertations & Projects
The TPA and LA can be activated with two methods: the “shape-driven method” where the appliance is made to match the final tooth position and the “force-driven method” where the appliance is made to make sure the force system delivered by it at the beginning is consistent with the planned tooth movement. This study compared the two methods in vitro quantitatively with typodont teeth and multi-axis force torque transducers in all three dimensions. Results: In the TPA first order activation, with comparable Fy (force on Y axis) reading, the shape-driven activation group had a significantly higher Mx (moment on X …
Neuropsychological Effects Of Pomegranate Supplementation Following Ischemic Stroke, John A. Bellone
Neuropsychological Effects Of Pomegranate Supplementation Following Ischemic Stroke, John A. Bellone
Loma Linda University Electronic Theses, Dissertations & Projects
Polyphenols are compounds found in fruits and vegetables that have antioxidant and anti-inflammatory properties. Mounting evidence suggests that dietary polyphenol intake can reduce the detrimental effects of various disease processes, and pomegranates have frequently been examined because of their particularly high polyphenol content. Since stroke induces both oxidative stress and inflammation and is currently the leading cause of long-term disability in the U.S., we sought to determine whether dietary supplementation with polyphenols could enhance cognitive recovery in individuals who had suffered an ischemic stroke. We administered polyphenols via 2 POMx pills containing polyphenols derived from pomegranates equivalent to the content …
Synthesis Of Huacat® Analogues As Novel Organocatalysts For The Formation Of Asymmetric C-C Bonds, Kenneth Laboy
Synthesis Of Huacat® Analogues As Novel Organocatalysts For The Formation Of Asymmetric C-C Bonds, Kenneth Laboy
Loma Linda University Electronic Theses, Dissertations & Projects
The synthesis of organic compounds with preferential stereochemistry is ubiquitous in the scientific community. A chemical reaction that asymmetrically induces one stereoisomer over another is achieved through the use of catalysts and various coupling reagents.1 Inorganic catalysts, such as TiCl4 and ZnCl2, have been documented for many decades as effective agents in the synthesis of asymmetric bonds, however, there are environmental limitations to their use. First, the asymmetric reactions involving these metal catalysts require solvents that are not environmentally-friendly, especially when used on an industrial scale and second, the metal catalysts are recycled when possible, however, there is always metal …
A Cbct Study Of Pharyngeal Airway Changes Due To Fixed Functional Appliances, Scott T. Peterson
A Cbct Study Of Pharyngeal Airway Changes Due To Fixed Functional Appliances, Scott T. Peterson
Loma Linda University Electronic Theses, Dissertations & Projects
Introduction: The purpose of this retrospective study, using head and neck Cone-Beam Computed Tomography (CBCT) images, was to measure and compare volumetric, area, and linear changes of the pharyngeal airway space in patients treated with a MARA or Herbst Class II correction appliances. Materials and Methods: Twenty-six patients treated with a MARA (mean age 13.2), nine with a Herbst (mean age 12.12) , and a control group twenty-five orthodontically treated class I patients (mean age 13.11). T1 and T2 CBCT images were measured and compared between the three groups for area, length, and width measurements along the velo-, oro-, and …
An Evaluation Of Root Length Change Measurements Using Intraoral Scan And Panoramic Radiographs, Elijah C. Wang
An Evaluation Of Root Length Change Measurements Using Intraoral Scan And Panoramic Radiographs, Elijah C. Wang
Loma Linda University Electronic Theses, Dissertations & Projects
Introduction: This study was intended to evaluate the accuracy of using panoramic radiographs to measure root length change over the course of orthodontic treatment, using intraoral scans of crowns, and a mathematical model to account for distortions in the radiographs. The study additionally evaluated whether a best-fit equation could be created from the calculated data to minimize differences to the measurements of root resorption made on CBCT scans. Materials and Methods: Twenty-one patients were selected who had comprehensive orthodontic treatment, and all teeth in the upper right quadrant were evaluated in this study. T1 and T2 CBCT images were compared …
Correlation Of Tooth Length Measurements Made On Cbct And 3t Mr Images, Andrew Scott Taylor
Correlation Of Tooth Length Measurements Made On Cbct And 3t Mr Images, Andrew Scott Taylor
Loma Linda University Electronic Theses, Dissertations & Projects
Objective. This study compared tooth length measurements made on cone beam computed tomography (CBCT) scans and 3-Tesla (3T) magnetic resonance (MR) scans performed with and without an alginate bite registration surrounding the crowns of the teeth. Materials and Methods. One CBCT scan, one MR scan with alginate bite registration, and one MR scan without bite registration were performed on 12 subjects. The alginate bite registration was used to provide a proton-rich material to surround proton-poor teeth in an attempt to improve visualization of teeth. DICOM formatted images from each of the three scans for each subject were oriented in all …
Relational Engagement And Empowerment: Establishing A Foundation To Address Gender And Power, Sarah K. Samman
Relational Engagement And Empowerment: Establishing A Foundation To Address Gender And Power, Sarah K. Samman
Loma Linda University Electronic Theses, Dissertations & Projects
Feminist informed therapists view relational distress as a complex reflection of the influences of larger disempowering discourses resulting in gendered power inequalities in heterosexual couple relationships. These disempowering discourses often manifest in males’ socialization to maintain autonomy compared to females’ socialization to orient toward the needs of others (Silverstein, Bass, Tuttle, Knudson-Martin, & Huenergardt, 2006). The general purpose of this study was to bridge the gap between feminist informed theory and practice using the Socio-Emotional Relationship Therapy (SERT; Knudson-Martin & Huenergardt, 2010) Model to relieve relational distress in heterosexual intimate partners often caused by these competing discourses toward a relational …
A Tele-Coaching Intervention To Support Families In The Npp+: An Experimental Mixed Method Design, Wendella Wray
A Tele-Coaching Intervention To Support Families In The Npp+: An Experimental Mixed Method Design, Wendella Wray
Loma Linda University Electronic Theses, Dissertations & Projects
Poverty is the single greatest threat to a child’s well-being. Poverty has been shown to exacerbate child maltreatment (CM) and minimize nurturing parenting. CM is a leading cause of death among children under the age of five in the United States. Both poverty and CM are major public health concerns worldwide with important implications for the family. For over three decades great focus has been placed on developing evidence-based (EB) parenting and family interventions to promote the well-being of high-risk families. Using a conceptual framework guided by elements of the social cognitive theory, attachment theory and family systems theory, this …
The Effect Of Orthodontic Treatment On Sagittal Root Position Of The Maxillary Central Incisor, Jeremy Haines
The Effect Of Orthodontic Treatment On Sagittal Root Position Of The Maxillary Central Incisor, Jeremy Haines
Loma Linda University Electronic Theses, Dissertations & Projects
Introduction: Sagittal root position (SRP) of maxillary incisors is an important factor in implant treatment planning. Kan et al defined four classes of SRP in an effort to aid implant placement treatment planning and these SRP classifications represent a novel approach to describing bone changes around the maxillary incisors. The effect of orthodontic tooth movement, specifically changes in inclination, on SRP is of interest in potentially facilitating immediate implant placement. Purpose: The purpose of this study was to use Cone Beam Computed Tomography (CBCT) to evaluate the adaptation of alveolar bone around the maxillary incisors as a result of orthodontic …
Ricketts Analysis Using Conventional And Dolphintm Generated Cbct Lateral Cephs, Yeganeh Parhizkar Jewell
Ricketts Analysis Using Conventional And Dolphintm Generated Cbct Lateral Cephs, Yeganeh Parhizkar Jewell
Loma Linda University Electronic Theses, Dissertations & Projects
Purpose: The aim of this study was to evaluate the difference between Ricketts analysis measurements made on Sirona Orthophos XG Plus (Sirona Dental Systems, Charlotte,NC) lateral cephalograms, and DolphinTM generated perspective and orthogonal lateral cephalograms from CBCT (NewTom 5G; QR srl, Verona, Italy). Materials and Methods: A Sirona digital lateral cephalogram and DophinTM synthesized CBCT lateral cephalograms of a radiographic phantom in orthogonal and perspective projections were created. Horizontal and vertical measurements were made in multiple planes on the radiographic phantom to compare each imaging modality. Twenty-five lateral cephalometric radiographs were selected retrospectively from the records of patients of …
Proteomic Profiling Of Serum Derived Exosomes From Prostate Cancer Patients, David Turay
Proteomic Profiling Of Serum Derived Exosomes From Prostate Cancer Patients, David Turay
Loma Linda University Electronic Theses, Dissertations & Projects
Touted among the major achievements in the diagnosis and management of Prostate cancer (PCa) in the past few decades has been, the dramatic decline of men with advanced/metastatic PCa at diagnosis coupled with a significant improvement ( >90%) in the five and ten year survival rates of the disease. Non-palpable PCa (potentially clinically treatable disease) now accounts for 70-80% of all newly diagnosed cases of PCa. Preceding these changes by about a decade was the introduction of Prostatic Specific Antigen (PSA) into clinical practice; first as biomarker for monitoring response to therapy and subsequently as a complementary screening tool. It …