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Articles 1 - 11 of 11
Full-Text Articles in Medicine and Health Sciences
Molecular Determinants Of Kaposi's Sarcoma-Associated Herpesvirus Tumorigenicity, Haixia Kong
Molecular Determinants Of Kaposi's Sarcoma-Associated Herpesvirus Tumorigenicity, Haixia Kong
LSU Master's Theses
A conditional silencing system using anti-gB siRNAs was devised to investigate the structure and function of the KSHV gB. Transient co-transfection of plasmids constitutively expressing gB and anti-gB siRNAs in 293 cells substantially inhibited gB mRNA levels and protein production. Similarly, transient expression of siRNAs into the basal cavity-based lymphoma cells (BCBL-1) caused substantial reduction of gB transcription and protein synthesis. TaqMan real-time PCR and infectivity assays showed that gB was essential for virion egress and infectivity. Transfection of a codon-optimized gB not recognized by the anti-gB siRNAs, efficiently rescued virion egress and infectivity in BCBL-1 cells in the presence …
Examining The Effects Of Non-Intensive Therapy On Word Retrieval, Speech Intelligibility And Quality Of Life Following Intensive Therapy, Hillary Leigh Goodwin
Examining The Effects Of Non-Intensive Therapy On Word Retrieval, Speech Intelligibility And Quality Of Life Following Intensive Therapy, Hillary Leigh Goodwin
LSU Master's Theses
The purpose of this study was to determine if involvement in intensive treatment would help a patient with aphasia, secondary to a cerebral vascular accident, accompanied by dysarthria, maintain skill levels during non-intensive treatment. A literature review uncovered numerous studies on intensive treatment. These studies discussed the improvements the subjects were able to make across various areas during the time of intensive treatment; however, very little research was available to indicate these subjects’ success when re-entering non-intensive treatment. This study proposed two specific questions: was the subject able to maintain word retrieval, speech intelligibility, and quality of life levels from …
Phenotypic Characterization Of Canine Cranial Cruciate Ligament Associated Synoviocytes, Sunil C. Vasanjee
Phenotypic Characterization Of Canine Cranial Cruciate Ligament Associated Synoviocytes, Sunil C. Vasanjee
LSU Master's Theses
Identification of synoviocytes surrounding the canine cranial cruciate ligament (CrCL) has not been investigated. Objectives 1) Develop and validate a technique to identify and quantify normal canine CrCL associated synoviocytes. 2) Compare synoviocyte phenotype proportions surrounding normal and abnormal canine CrCLs Design In vitro experimental Animals Cranial cruciate ligaments from 4 intact female and 6 intact adult male mixed-breed dogs (objective 1) and from 8 adult female hound dogs (objective 2) Methods Objective 1) Normal CrCLs - CD18 and HSP25 epitopes were colocalized using immunohistochemistry. Sagittal sections were quantified in the proximal, middle, and distal aspects of each section. Western …
Randomized Controlled Trial Evaluating Adeno-Momp And Momp Dna Vaccines Against Chlamydophila Psittaci Challenge In Cockatiels (Nymphicus Hollandicus), David Sanchez-Migallon Guzman
Randomized Controlled Trial Evaluating Adeno-Momp And Momp Dna Vaccines Against Chlamydophila Psittaci Challenge In Cockatiels (Nymphicus Hollandicus), David Sanchez-Migallon Guzman
LSU Master's Theses
Chlamydophila psittaci causes severe disease in birds and humans, and important economical losses in the avian companion and poultry industry. Vaccines are the most cost-effective measure to control and help prevent infectious diseases, but to date there is no commercial vaccine available. A randomized clinical trial was conducted to assess the efficacy of two recombinant DNA vaccines against C. psittaci in Cockatiels (Nymphicus hollandicus). The first recombinant DNA vaccine has a gene encoding MOMP and the immunostimulant chitosan (MOMP DNA vaccine). The second recombinant DNA vaccine, contained the gene encoding MOMP that was vectored by a replication defective human adenovirus …
Vocal Fold Vibratory Characteristics Pre And Post Phonosurgery Investigated By Stroboscopy, Brittany Anne Durand
Vocal Fold Vibratory Characteristics Pre And Post Phonosurgery Investigated By Stroboscopy, Brittany Anne Durand
LSU Master's Theses
The purpose of this study was to investigate voice audio perceptual outcomes and true vocal fold vibratory characteristics following surgery for removal of vocal fold polyp. The specific aims of this study were 1) to determine vocal fold vibratory changes following surgery and 2) to compare these changes to audio perceptual ratings and Voice Handicap Index (VHI) scores. It was hypothesized that significant vibratory changes would occur following surgery and that Voice Handicap Index scores and audio perception ratings would correlate 1 week before surgery, 1 week following surgery, and 1 month following surgery. The most improved structural, functional, and …
Examining The Effects Of Non-Intensive Therapy On Word Retrieval, Apraxic Errors And Quality Of Life Following Intensive Therapy, Erin Lofton Cain
Examining The Effects Of Non-Intensive Therapy On Word Retrieval, Apraxic Errors And Quality Of Life Following Intensive Therapy, Erin Lofton Cain
LSU Master's Theses
The purpose of this study was to determine if given a period of intensive aphasia therapy a patient diagnosed with aphasia and an accompanying apraxia would maintain, gain, or lose skills during non-intensive therapy. A literature review revealed that intensive therapy has been shown to increase a patient's skill level in various areas. However, very little research was found that focused on how these patients' perform when reintroduced to typical aphasia therapy. This study proposed three specific questions: if the participant would retain her current level of word retrieval functioning evident after intensive therapy, if the participant would retain her …
Effects Of Centrifugation On Equine Spermatozoa Immediately And After Cooling For 24 Hours, Jose Augusto Len
Effects Of Centrifugation On Equine Spermatozoa Immediately And After Cooling For 24 Hours, Jose Augusto Len
LSU Master's Theses
Len, Jose Augusto, MVZ, Universidad de Guadalajara, 1994 Master of Science, Summer Commencement, 2008 Major: Veterinary Medical Sciences Effects of Centrifugation on Equine Spermatozoa Immediately and After Cooling for 24 Hours Thesis directed by Professor Bruce Eilts Pages in thesis, 60. Words in abstract, 245. ABSTRACT The objectives of this study were to determine the effects of centrifugation on equine sperm progressive motility, plasma membrane integrity (viability), and acrosome integrity. We hypothesized that high centrifugation forces would be detrimental to equine sperm, yet recovery rates would increase. Ejaculates from six stallions were collected, extended (INRA96) to a concentration of 25 …
Baby Signs: Caregiver Perceptions Of Their Use And Benefit To Children, Leah Catherine Legere
Baby Signs: Caregiver Perceptions Of Their Use And Benefit To Children, Leah Catherine Legere
LSU Master's Theses
Gesture use is a precursor to spoken language, and children who exhibit frequent use of gesture have higher rates of speech comprehension and production when tested between 13 and 15 months of age (Bates et al, 1989). The purpose of this study was to learn more about caregivers’ perceptions of the use and benefits of sign to their children. Fifty-three caregivers were recruited for the study, and 33 (62%) of these caregivers reported that they had used or were currently using baby signs with one of their children. Six (18%) of these caregivers also reported that their children presented developmental …
The Effectiveness Of Contextualization On Second Language Acquisition Using The Situational Discourse Semantic Model, Alice Marie Johnson
The Effectiveness Of Contextualization On Second Language Acquisition Using The Situational Discourse Semantic Model, Alice Marie Johnson
LSU Master's Theses
In traditional classrooms a second language is taught via thematic word sets, grammatical explanations, and patterned syntactic practice. This study compared the traditional teaching approach to a scaffolded teaching approach, consisting of words taught within a narrative context. Five fifth-grade students were taught Spanish as a second language during a ten-week intervention. Vocabulary learning and sentence generation were measured following each session, as well as a pre-posttest measure. Results showed that print was an important support used by participants in the traditional condition. However across time, vocabulary learning and sentence length increased significantly more in the scaffolded condition.
A Comparison Of Morphophonic Faces And The Picture Exchange Communication System On The Production Of Verbal Communication In Preschoolers With Autism, Ashley Nicole Bourque
A Comparison Of Morphophonic Faces And The Picture Exchange Communication System On The Production Of Verbal Communication In Preschoolers With Autism, Ashley Nicole Bourque
LSU Master's Theses
Children with Autism Spectrum Disorder (ASD) exhibit difficulties with both verbal and nonverbal language with approximately 50% of children diagnosed with autism remaining functionally mute into adulthood (Charlop & Haymes, 1994; Charlop-Christy, Carpenter, Le, LeBlanc, & Kellet, 2002). This study explored intervention using the Picture Exchange Communication System (PECS) for two nonverbal preschoolers with ASD. The effects of PECS using two picture systems, Picture and Words (P&W) and MorphoPhonic (MPh) picture word, was assessed in the communicative outcomes after 6 weeks of intervention. This study asked if MPh picture words would elicit more picture-exchange communication acts in functional contexts than …
Comparative Roles Of Herpes Simplex Virus Type 1 (Hsv-1) Glycoproteins In Cytoplasmic Virion Egress, Hyuncheol Lee
Comparative Roles Of Herpes Simplex Virus Type 1 (Hsv-1) Glycoproteins In Cytoplasmic Virion Egress, Hyuncheol Lee
LSU Master's Theses
HSV-1 acquires its final envelope by budding into cytoplasmic vesicles thought to be derived from Trans-Golgi Network (TGN) membranes. This process is facilitated by interactions among the carboxyl termini of viral glycoproteins and tegument proteins. To investigate the relative importance of different viral glycoproteins in cytoplasmic virion morphogenesis, a set of recombinant viruses were constructed silencing expression of the glycoprotein E (ΔgE), the carboxyl terminus of glycoprotein D (gDΔcp), and the membrane protein UL20 (ΔUL20). In addition, recombinant viruses were constructed having the ΔgE+gDΔcp, and the ΔgE+ΔgM (glycoprotein M) deletions. These recombinant viruses were constructed using the double-red, site-directed mutagenesis …