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Full-Text Articles in Medicine and Health Sciences

The Association Of Anti-P And Early Abortion, R. Shirey, P. Ness, T. Kickler, J. Rock, N. Callan, W. Schlaff, Jennifer Niebyl May 2013

The Association Of Anti-P And Early Abortion, R. Shirey, P. Ness, T. Kickler, J. Rock, N. Callan, W. Schlaff, Jennifer Niebyl

Jennifer R Niebyl

The current report details the serologic findings in a case reported previously of a P1k woman, para 0 gravida 13, who was treated during her fourteenth pregnancy with plasmapheresis to reduce the anti-P titer. These studies suggest that anti-P can induce early abortion in Pk women and that the abortions are immunologically mediated. Further, this case supports the disputed proposal that the anti-P component of anti-PP1Pk is responsible for pregnancy loss in p women.


Plasmapheresis For The Treatment Of Repeated Early Pregnancy Wastage Associated With Anti-P, J. Rock, R. Shirey, H. Braine, P. Ness, T. Kickler, Jennifer Niebyl May 2013

Plasmapheresis For The Treatment Of Repeated Early Pregnancy Wastage Associated With Anti-P, J. Rock, R. Shirey, H. Braine, P. Ness, T. Kickler, Jennifer Niebyl

Jennifer R Niebyl

It has been proposed that the blood group antibody, anti-P, produced by p or Pk individuals may cause abortion early in pregnancy. The authors have studied and successfully treated a Pk woman with anti-P who had 13 consecutive first-trimester miscarriages. Anti-P was implicated as the cause of repeated pregnancy loss after extensive clinical, endocrinologic, immunologic, and chromosomal evaluations. To remove P blood group antibodies, plasmapheresis was begun at five weeks' gestation during the 14th pregnancy with one plasma volume exchange two to three times per week. This therapy resulted in a reduction in the titer of anti-P, and the patient …


A False Negative Oxytocin Challenge Test, W. Mccranie, Jennifer Niebyl May 2013

A False Negative Oxytocin Challenge Test, W. Mccranie, Jennifer Niebyl

Jennifer R Niebyl

A negative oxytocin challenge test has been considered a very reassuring finding in managing pregnancies in which the fetus is at risk from uteroplacental insufficency. In the case described here a fetal death in utero occurred 4 days after a negative oxytocin challenge test in a Class D diabetic patient, but in that period of time the patient's metabolic status deteriorated. A negative oxytocin challenge test does not protect the fetus from a subsequent acute event such as abruptio placentae, a cord accident, or diabetic ketoacidosis.


Doppler Ultrasound And Maternal Erythrocyte Fragility, G. Bause, Jennifer Niebyl, R. Sanders May 2013

Doppler Ultrasound And Maternal Erythrocyte Fragility, G. Bause, Jennifer Niebyl, R. Sanders

Jennifer R Niebyl

Maternal erythrocyte fragility was studied in eight controls and in 16 women exposed to Doppler ultrasound monitoring during labor. Blood samples were taken before and after Doppler monitoring and no significant change in erythrocyte fragility was seen, although there was a trend toward increased fragility in patients exposed continuously for more than seven hours.


Treatment Of Premature Labor With Indomethacin, D. Blake, Jennifer Niebyl, R. White, K. Kumor, N. Dubin, J. Robinson, P. Egner May 2013

Treatment Of Premature Labor With Indomethacin, D. Blake, Jennifer Niebyl, R. White, K. Kumor, N. Dubin, J. Robinson, P. Egner

Jennifer R Niebyl

No abstract provided.


Carbamazepine Levels In Pregnancy And Lactation, Jennifer Niebyl, D. Blake, J. Freeman, R. Luff May 2013

Carbamazepine Levels In Pregnancy And Lactation, Jennifer Niebyl, D. Blake, J. Freeman, R. Luff

Jennifer R Niebyl

An epileptic patient whose seizures were controlled with carbamazepine and primidone was followed throughout pregnancy and lactation. Blood levels of primidone decreased during pregnancy and rose postpartum requiring dosage adjustments. Pharmacologically insignificant amounts of the drug were detected in breast milk. A review of the literature revealed 94 infants exposed to carbamazepine in utero and no evidence to date that this drug carries a teratogenic risk.


Cervical Cancer Diagnosed Shortly After Pregnancy: Prognostic Variables And Delivery Routes, A. Sood, J. Sorosky, N. Mayr, B. Anderson, R. Buller, Jennifer Niebyl May 2013

Cervical Cancer Diagnosed Shortly After Pregnancy: Prognostic Variables And Delivery Routes, A. Sood, J. Sorosky, N. Mayr, B. Anderson, R. Buller, Jennifer Niebyl

Jennifer R Niebyl

No abstract provided.


Vitamin B6 Is Effective Therapy For Nausea And Vomiting Of Pregnancy: A Randomized, Double-Blind Placebo-Controlled Study, V. Sahakian, D. Rouse, S. Sipes, N. Rose, Jennifer Niebyl May 2013

Vitamin B6 Is Effective Therapy For Nausea And Vomiting Of Pregnancy: A Randomized, Double-Blind Placebo-Controlled Study, V. Sahakian, D. Rouse, S. Sipes, N. Rose, Jennifer Niebyl

Jennifer R Niebyl

Fifty-nine women completed a randomized, double-blind placebo-controlled study of pyridoxine hydrochloride (vitamin B6) for the treatment of nausea and vomiting of pregnancy. Thirty-one patients received vitamin B6, 25-mg tablets orally every 8 hours for 72 hours, and 28 patients received placebo in the same regimen. Patients were categorized according to the presence of vomiting: severe nausea (score greater than 7) or mild to moderate nausea (score of 7 or less). The severity of nausea (as graded on a visual analogue scale of 1-10 cm) and the number of patients with vomiting over a 72-hour period were used to evaluate response …