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Articles 1 - 11 of 11
Full-Text Articles in Medicine and Health Sciences
A Vicious Cycle Of Fear Of Falling Avoidance Behavior In Parkinson’S Disease: A Path Analysis, Merrill R. Landers, Kameron M. Jacobson, Nicole E. Matsunami, Hannah E. Mccarl, Michelle T. Regis, Jason K. Longhurst
A Vicious Cycle Of Fear Of Falling Avoidance Behavior In Parkinson’S Disease: A Path Analysis, Merrill R. Landers, Kameron M. Jacobson, Nicole E. Matsunami, Hannah E. Mccarl, Michelle T. Regis, Jason K. Longhurst
Integrated Health Sciences Faculty Publications
Background: Postural instability (PI) in Parkinson's disease (PD) is associated with several negative downstream consequences. Objective: The purpose was to explore the validity of a theoretical model of these downstream consequences arranged in a vicious cycle wherein PI leads to decreased balance confidence, which in turn leads to increased fear of falling (FOF) avoidance behavior, which in turn leads to decreased physical conditioning, which then feeds back and negatively affects PI. Methods: A path analysis of cross-sectional data from 55 participants with PD was conducted. The four constructs in the model connected in succession were: 1. PI (principal components analysis …
Effects Of Acute Cocoa Supplementation On Postprandial Apolipoproteins, Lipoprotein Subclasses, And Inflammatory Biomarkers In Adults With Type 2 Diabetes After A High-Fat Meal, Dustin D. Davis, Rickelle Tallent, James W. Navalta, Anthony Salazar, Timothy J. Lyons, Arpita Basu
Effects Of Acute Cocoa Supplementation On Postprandial Apolipoproteins, Lipoprotein Subclasses, And Inflammatory Biomarkers In Adults With Type 2 Diabetes After A High-Fat Meal, Dustin D. Davis, Rickelle Tallent, James W. Navalta, Anthony Salazar, Timothy J. Lyons, Arpita Basu
Integrated Health Sciences Faculty Publications
Dyslipidemia and inflammation exacerbate postprandial metabolic stress in people with diabetes. Acute dietary supplementation with polyphenols shows promise in improving postprandial metabolic stress in type 2 diabetes (T2D). Cocoa is a rich source of dietary polyphenols with demonstrated cardioprotective effects in adults without diabetes. To date, the acute effects of cocoa on postprandial lipids and inflammation have received little attention in the presence of T2D. This report expands on our earlier observation that polyphenol-rich cocoa, given as a beverage with a fast-food-style, high-fat breakfast, increased postprandial high-density lipoprotein-cholesterol (HDL-C) in adults with T2D. We now test whether polyphenol-rich cocoa modulated …
Behavior Change Following Pain Neuroscience Education In Middle Schools: A Public Health Trial, Adriaan Louw, Regina Landrus, Jessie Podolak, Patricia Benz, Jen Delorenzo, Christine Davis, Alison Rogers, Kathy Cooper, Colleen Louw, Kory Zimney, Emilio J. Puentedura, Merrill R. Landers
Behavior Change Following Pain Neuroscience Education In Middle Schools: A Public Health Trial, Adriaan Louw, Regina Landrus, Jessie Podolak, Patricia Benz, Jen Delorenzo, Christine Davis, Alison Rogers, Kathy Cooper, Colleen Louw, Kory Zimney, Emilio J. Puentedura, Merrill R. Landers
Integrated Health Sciences Faculty Publications
Chronic pain and the opioid epidemic need early, upstream interventions to aim at meaningful downstream behavioral changes. A recent pain neuroscience education (PNE) program was developed and tested for middle-school students to increase pain knowledge and promote healthier beliefs regarding pain. In this study, 668 seventh-grade middle-school students either received a PNE lecture (n = 220); usual curriculum school pain education (UC) (n = 198) or PNE followed by two booster (PNEBoost) sessions (n = 250). Prior to, immediately after and at six-month follow-up, pain knowledge and fear of physical activity was measured. Six months after the initial intervention school, …
A Mobile App Specifically Designed To Facilitate Exercise In Parkinson Disease: Single-Cohort Pilot Study On Feasibility, Safety, And Signal Of Efficacy, Merrill R. Landers, Terry D. Ellis
A Mobile App Specifically Designed To Facilitate Exercise In Parkinson Disease: Single-Cohort Pilot Study On Feasibility, Safety, And Signal Of Efficacy, Merrill R. Landers, Terry D. Ellis
Integrated Health Sciences Faculty Publications
Background: Many people with Parkinson disease do not have access to exercise programs that are specifically tailored to their needs and capabilities. This mobile app allows people with Parkinson disease to access Parkinson disease–specific exercises that are individually tailored using in-app demographic questions and performance tests which are fed into an algorithm which in turn produces a video-guided exercise program. Objective: To test the feasibility, safety, and signal of efficacy of a mobile app that facilitates exercise for people with Parkinson disease. Methods: A prospective, single-cohort design of people with Parkinson disease who had downloaded the 9zest app for exercise …
Estimated Cardiorespiratory Fitness Is Associated With Reported Depression In College Students, Sharon Jalene, Jennifer Pharr, Guogen Shan, Brach Poston
Estimated Cardiorespiratory Fitness Is Associated With Reported Depression In College Students, Sharon Jalene, Jennifer Pharr, Guogen Shan, Brach Poston
Integrated Health Sciences Faculty Publications
Depression is a serious but treatable health issue that affects college students at an alarming rate. Improved cardiorespiratory fitness (CRF) decreases depression risk and severity but this relationship has not been fully evaluated in the college student population. Non-exercise estimated CRF (eCRF) could be used to identify students at risk for or suffering from depression. This study investigated the associations of depression and eCRF in college students. Participants (N = 437) completed a survey which included demographic and student-status questions, eCRF variables, and a validated depression instrument. Descriptive, chi-square, t-test, regression, and odds ratio analyses were employed. Depression was associated …
Further Analyses Of The Safety Of Verubecestat In The Phase 3 Epoch Trial Of Mild-To-Moderate Alzheimer’S Disease, Michael F. Egan, Yuki Mukai, Tiffini Voss, James Kost, Julie Stone, Christine Furtek, Erin Mahoney, Jeffrey L. Cummings, Pierre N. Tariot, Paul S. Aisen, Bruno Vellas, Christopher Lines, David Michaelson
Further Analyses Of The Safety Of Verubecestat In The Phase 3 Epoch Trial Of Mild-To-Moderate Alzheimer’S Disease, Michael F. Egan, Yuki Mukai, Tiffini Voss, James Kost, Julie Stone, Christine Furtek, Erin Mahoney, Jeffrey L. Cummings, Pierre N. Tariot, Paul S. Aisen, Bruno Vellas, Christopher Lines, David Michaelson
Integrated Health Sciences Faculty Publications
Background: Verubecestat, a BACE1 inhibitor that reduces Aβ levels in the cerebrospinal fluid of humans, was not effective in a phase 3 trial (EPOCH) of mild-to-moderate AD and was associated with adverse events. To assist in the development of BACE1 inhibitors, we report detailed safety findings from EPOCH. Methods: EPOCH was a randomized, double-blind, placebo-controlled 78-week trial evaluating verubecestat 12 mg and 40 mg in participants with mild-to-moderate AD diagnosed clinically. The trial was terminated due to futility close to its scheduled completion. Of 1957 participants who were randomized and took treatment, 652 were assigned to verubecestat 12 mg, 652 …
Visual And Auditory Attention In Hyperactive And Normal Boys, Ronald T. Brown
Visual And Auditory Attention In Hyperactive And Normal Boys, Ronald T. Brown
Integrated Health Sciences Faculty Publications
No abstract provided.
Remediation Efforts For Hyperactivity: Training In Attention Or Inhibitory Control, Ronald T. Brown
Remediation Efforts For Hyperactivity: Training In Attention Or Inhibitory Control, Ronald T. Brown
Integrated Health Sciences Faculty Publications
No abstract provided.
Some Misgivings About Locus Of Control Orientation And Its Relationship To Intelligence, Academic Achievement, And Delinquency, Ronald T. Brown
Some Misgivings About Locus Of Control Orientation And Its Relationship To Intelligence, Academic Achievement, And Delinquency, Ronald T. Brown
Integrated Health Sciences Faculty Publications
No abstract provided.
Modeling: A Cognitive Approach In Ameliorating Impulsivity In Hyperactive Children, Ronald T. Brown
Modeling: A Cognitive Approach In Ameliorating Impulsivity In Hyperactive Children, Ronald T. Brown
Integrated Health Sciences Faculty Publications
No abstract provided.
A Developmental Analysis Of Attentional Processes In Educabley Mentally Retarded And Normally Developing Children, Ronald T. Brown
A Developmental Analysis Of Attentional Processes In Educabley Mentally Retarded And Normally Developing Children, Ronald T. Brown
Integrated Health Sciences Faculty Publications
No abstract provided.