Medicine and Health Sciences Commons^™

I'Ve Been Diagnosed: A Champion! Crohn's & Colitis Family Day, Samantha M. Goldberg

Honors College Theses

This Honors thesis outlines the creation of “I’ve Been Diagnosed: A Champion! Crohn’s & Colitis Family Day”—an experience designed to provide Southeast Georgia children and families affected by inflammatory bowel disease (IBD) an opportunity to enhance community involvement and build a support network through therapeutic recreation, team-based activities, education, and a positive family-centered environment. Following the nursing process focusing on the community as the patient, this paper is organized by assessment, diagnosis, planning, intervention, and evaluation. A literature review was conducted and interviews with a medical professional and a patient were completed. Specific interventions were planned using the nursing process …

Pink Goes Red For A Day: Is Your Heart Healthy?, Quierra W. Jones

Honors College Theses

There is a major lack of public health education among college aged students at many colleges and universities across the country. Even further, many minority college students are unfamiliar with one of the most life-threatening health issues that affect them the most: heart health. As a nursing student and member of Alpha Kappa Alpha Sorority Inc., I strive to uphold our “service to all mankind” motto and also educate the public about important heart health matters. On February 4, 2014, I presented a program through my sorority entitled Pink Goes Red for a Day in which I educated the primarily …

A Qualitative Examination Of Optimal Professional Traits Of Physical Therapists. – An Exploratory Investigation, Nicholas G. Wood

Honors College Theses

Physical therapists are constantly searching for aspects of their professional practice to improve, in order to enhance interactions with patients, eventually leading to a more successful practice (Resnek & Jensen, 2003). Although this is the case, limited research has been found which has examined optimal qualities of physical therapists from neither a qualitative perspective, nor based upon their location. Thus, the purpose of this study is to use a qualitative approach to describe optimal qualities necessary for a successful physical therapy practice. In addition, this study aims to determine if therapists practicing in a rural community describe different qualities than …

Barriers To Music Therapy In The Care Of Those With Alzheimer's/Dementia, Karin E. Kvam

Honors College Theses

This pilot study examines the barriers caregivers encounter when implementing music therapy in the care of those with Alzheimer’s/dementia. An 8-question survey was distributed at two long-term care facilities and an Alzheimer’s support group to understand how often and in what ways music therapy is utilized, as well as what barriers caregivers face when using the therapy. Results indicated that, although the majority of caregivers report using music therapy, it is not implemented as frequently as it could or should be. Caregivers report a knowledge deficit as the main reason for not implementing music therapy. The data suggests that an …

Evidence Based Design In Healthcare: An Applied Study On The Impacts Of Interior Design For Cerebral Palsy, Katie D. Phillips

Honors College Theses

Evidence Based Design (EBD) is an informed approach to design where designers base their decisions on quantitative and qualitative research. The design of the Universal Access Center for United Cerebral Palsy, discussed in this paper, encapsulates this approach to design. The five stages of EBD and how they were achieved within this project is defined. In the first phase, programming, current trends in healthcare as well as issues surrounding design for adults with Cerebral Palsy (CP) are discussed. In schematic design, initial issues of the project are resolved, and creative ideas are explored leading to the design development stage. In …

The Effects Of Latent Stage Diabetic Education And Tele-Health Reinforcement On The Knowledge Of Low-Income Diabetic Patients, Hannah M. Chicowlas

Honors College Theses

Diabetes is a chronic disease that affects millions globally. Poverty and obesity are factors that affect the development and progression of this disease. Although education has been identified as a factor affecting treatment adherence, on-going education for diabetes typically occurs in the early stages. This pilot study consisted of a quantitative, comparative study utilizing tele-health as the primary form of educational reinforcement for latent stage, low-income diabetics. Six clients agreed to participate. It focused on participants from a local clinic in Georgia. All participants live at or below 200% of the federal poverty guidelines. An initial survey was followed by …

Identification Guide To Larval Stages Of Ticks Of Medical Importance In The Usa, Kymbreana Coley

Honors College Theses

Scanning Electron Micrographs were prepared of four morphologically diagnostic regions (dorsal capitulum, ventral capitulum, scutum, leg coxae) for the larval stage of the 16 species of ixodid (hard) ticks known to parasitize humans in the USA. These species are: Amblyomma americanum, A. maculatum, A. mixtum, A. tuberculatum, Dermacentor albipictus, D. andersoni, D. occidentalis, D. variabilis, Haemaphysalis leporispalustris, Ixodes angustus, I. cookei, I. pacificus, I. scapularis, I. spinipalpis, I. texanus, and Rhipicephalus sanguineus. Based on the morphological characters observed, a dichotomous identification key to ixodid larvae that parasitize humans in the USA was prepared. Common names, hosts and geographical distributions are …

Sternal Precautions: Is It Necessary To Restrict Our Patients?, Lauren Belyea

Honors College Theses

This paper is based on the inquiry about the effects of sternal precautions as part of a patient’s recovery following a sternotomy. It is important to explore this because nurses should always be asking themselves “why am I doing what I am doing with my patients?” “Which of my practices are evidence based and which do not have any evidence to support them?” (MeInyk, 2009). If sternal precautions are indeed overly restrictive and preventing patients from achieving the best possible recovery outcomes, it is the job of the nurse and other healthcare providers to make changes to the current practice.

Alcohol And Drug Use Amongst College Students In Relation To Sexual Abuse, Christyn Hollingsworth

Honors College Theses

The impact of child sexual abuse (CSA) and traumatic sexual experiences has been the subject of multiple studies in which harm was found. Among these harms are emotional distress, psychological issues, and substance abuse. This research analyzed and compared the responses to questions pertaining to substance use and attitudes regarding sexual interactions between college aged students with and without a history of sexual abuse. The participant’s answers were run through an ANOVA to determine statistical variance. Based on prior research, it was expected that victims consume alcohol and use drugs more frequently than non-victims in significant amounts. The findings in …

Modeling Hedonic Processing And Anhedonia In Depression, Kevin Mercado

Honors College Theses

Depression is characterized by low positive emotion and a lack of pleasurable experiences, or anhedonia. Past studies have emphasized controlling negative affect, but there is an emerging trend in the depression literature to focus on positive emotion. The current study employed several psychophysiological tools, postauricular reflex, startle blink reflex, and event-related potential (ERP) components such as P3 and the late positive potential (LPP), to assess the dissociable components in positive emotion (consummatory and anticipatory processes). In addition, several different hypotheses of emotional dysfunction were evaluated to accurately model deficits in positive emotionality. A majority of the psychophysiological tools used supported …

The Examination Of Healthy Eating Across Cultures: An Existential Phenomenological Approach, Sarah K. Simpson

Honors College Theses

Adhering to a healthy eating plan has been a topic of discussion across World regions. Moreover, Americans often attempt to mimic the eating habits of other regions of the world, such as the Mediterranean or Eastern Asia, in an attempt to live a long and healthy life. Satia et al., (2000) suggest that healthy eating perceptions can be influenced by food and beverage exposure, family norms, preparation methods, and geographic locations. Although this is the case, little research has been found which has examined healthy eating perceptions across regions from a qualitative perspective. Thus, the purpose of this study is …

An Examination Between Swimming Ability, Gender, And Race- An Exploratory Investigation, Laynie E. Brown

Honors College Theses

One of the leading causes of unintentional death worldwide is drowning. From 2005-2009, an estimated 3, 107 people in the United States over the age of fifteen died from drowning (Peden, Oyegbite, & Ozanne-Smith, 2008). Research has found higher amounts of drowning deaths to be males than females and African-American than Caucasian (Saluja et al., 2005). However, no significant differences have been found in real or perceived water competency between gender or age groups (Moran et al., 2012). Thus, the purpose of this study was to examine ability to swim between gender, race, and school classification of college students. Quantitative …

Biomechanical Analysis Of Gait Kinetics Resulting From Use Of A Vacuum Socket On A Transtibial Prosthesis, Maria De Lourdes Ramos Gonzalez

Honors College Theses

The technology and design of lower limb prosthetics have evolved greatly since their introduction. The current study proposed to compare the effects of a conventional pin socket attachment and a vacuum socket attachment for a transtibial amputee. Whereas traditional measurements of gait utilize force plates and camera systems, this study made use of a small tri-axial load cell located at the base of the socket to measure the forces and moments exerted during a regular gait cycle. The hypothesis tested stated that a vacuum pump socket attachment, when compared to a non-vacuum (pin) socket, will have a significant effect on …

Killing And Letting Die: The Irrelevant Distinction, Sarah Beth Shaw

Honors College Theses

The object of this essay is to explain why the distinctions made in euthanasia between killing vs. letting die and willingness to kill vs. unwillingness to kill are not relevant to real life euthanasia cases. The specific purpose of the research is to isolate the relevant factor for debate when discussing the morality of euthanasia. It begins with a brief examination of some vocabulary that is commonly used when discussing euthanasia. Following this is a quick overview of what the word euthanasia meant in the ancient Greco-Roman world compared to what it means in the modern vernacular. I use an …

Polyethylene Glycol Containing Rompolymers For The Modification Of Neuro-Protective Hemoglobin, Andrea L. Mccollum

Honors College Theses

Polyethylene glycol (PEG) has shown the ability to improve compatibility when used in combination with cell-free hemoglobin in the treatment of traumatic brain injuries. It has been demonstrated that the covalently bonded PEG increases the hydrodynamic radius of the hemoglobin and hence generates a physical barrier while slowing down the oxygen delivery of the strongly oxidative hemoglobin. In this context, I have been working on the development of synthetic pathways to incorporate PEG into monomers and polymers through both direct modification of (7-oxa)norbornene derivatives and post polymerization modification. Starting from the (7-oxa)norbornene anhydride derivatives, we have developed pathways to cationic …

Photodynamic Cancer Therapy A Study Of The Photolysis Reaction Between Porphyrin And 9,10-Diphenylanthracene, James Z. Akins

Honors College Theses

Photodynamic therapy (PDT) is a method of combating cancerous tumors. PDT works when certain molecules called photosensitizers absorb light and transfer that energy to dissolved oxygen in solution. Next, this singlet oxygen will interfere with nearby molecules that are necessary for cancer cells to function. This research focuses on the kinetics (rates) of the reaction with respect to the photosensitizer, light, and the target molecule. A laser set at 514nm was used in photolysis with the photosensitizer 5,10,15,20-Tetrakis(2,3,5,6-tetrafluorophenyl)porphyrin (TPP). To mimic cancer cells and monitor the effectiveness of the chosen photosensitizer, 9,10-Diphenylanthracene (DPA) was used as the target molecule. In …

Little Emperors And An Army Of Orphans: The Government’S Control Over The Idea Of Family In An Overpopulated World, Corinna L. Miller

Honors College Theses

This research elaborates on the connection between governmental policies for population control and the psychological effects felt by its citizens. Governments enact laws to form and shape their country, but when plans to benefit society as a whole overspill into the personal rights of families, there can be unforeseen consequences that span across cultural, economic and physiological wellbeing. These side effects can have debilitating outcomes for countless generations to come, even after the policy has been abolished. In an age where exponential population growth is a severe problem, this study attempts to understand what happens when governmental policies influence the …

Early Life Stress, Drug Abuse, Exercise Effects On Bdnf And Sex-Influenced Excercise Differences, Karissa Dold

Honors College Theses

In 2011, the U.S. reported 3 million child maltreatment cases, an uncomfortably high but recurring figure each year. Research shows exposure to early life stress (ELS) increases an individual’s susceptibility to substance abuse, specifically of nicotine, alcohol, and cocaine. Increased susceptibility may result from dysregulation of the HPA axis sustaining activation into adulthood after ELS. Hyperactivation of the HPA axis significantly reduces hippocampal BDNF, a neurotrophin involved in neuronal growth and plasticity. Reduced hippocampal BDNF may be a factor in substance abuse vulnerability. Additionally, research shows exercise protects hippocampal BDNF from stress induced down-regulation. To explore these relationships, this study …

Diagnostic Interaction: First-Person Patient Narratives On Hacking's Looping Effects And The Normative Status Of Psychiatric Nosology, Corinne Jager

Honors College Theses

What is the interaction between a psychiatric patient and their diagnosis? How do they respond to being classified? A number of philosophical theories attempt to explain the interaction between the diagnosed patient and their classification. Ian Hacking develops an account of interaction which holds that objects of human science classification are influenced by the awareness of the classification in a way that changes both the classification and its object. Hacking thinks that psychiatric patients are “interactive kinds” whose awareness of their classification causes changes in the individuals' experience of themselves, and thus changes in their classification. Hacking claims that these …

Identification Of Enzymes Causing Redox Cycling, Causing Oxidative Stress And Damaging Mitochondria, Kiran Sebastian

Honors College Theses

Oxidative stress is thought to contribute to the death of dopamine neurons and the consequential progression of Parkinson’s disease. Redox cycling of quinones, including compounds formed by dopamine oxidation, can lead to oxidative stress and damaging of the mitochondria. Which enzymes catalyze the redox cycling of quinones is unknown, however. Inhibitors of the mitochondrial respiratory chain (cyanide, rotenone) do not inhibit redox cycling. Mitochondrial NAD(P)H:quinone oxidoreductases are likely candidates, but dicumarol, a common inhibitor of such enzymes is not effective. We observed that Cibacron Blue does indeed inhibit NADH-dependent redox cycling to an extent. Our data shows that the rate …

Physical Activity And Exercise During Adolescence And Young Adulthood Can Act As Preventative Measures Against The Development Of Osteoporosis In Elderly People, Christine C. Center

Honors College Theses

Osteoporosis, “the silent killer,” is responsible for 8.9 million annual fractures. Although not bound to these factors, osteoporosis typically targets females that are post-menopausal and have a family history of the disease. Osteoporosis is caused by a decrease in bone mass density. Physical activity and exercise and often spoken about when the topic of osteoporosis is discussed because of the impact they have on maintaining bone mass density in an effort to delay osteoporosis. This paper first provides an overview of osteoporosis, explanation of methods of diagnosing osteoporosis, risk factors, complications and treatment for osteoporosis. Topics covered include, bone mass …

A New Approach To An Old Problem: Defining Nursing’S Role In Successful Transitions To Long-Term Residential Care, Kyleen Aldrich

Honors College Theses

A growing body of nursing research addresses the transitional period for older adults entering long-term residential care. However, gaps exist in our understanding of nursing’s role in the transition process. Our aim is to examine the available evidence and develop a model of nursing strategies and interventions to ease the transition to long-term care. This model describes interventions that nurses can incorporate into everyday practice.

A literature review was conducted to examine the transitional care needs and interventions for older adults with a goal of developing a model addressing transitions to long-term care.

Most nursing studies provided descriptive information about …

Association Of Genetic Variation, Gene Expression, And Protein Abundance Within The Natriuretic Peptide Pathway, Bipin Sunkara

Honors College Theses

Background: The natriuretic peptide (NP) system is a critical physiologic pathway in heart failure, but there is marked individual variability in its functioning which may be genetic in origin. We investigated how genetic variations in NP pathway genes correlate with gene expression and protein abundance.

Methods: DNA, RNA, and tissue from human kidney (n=77) were obtained. Kidney was chosen as target tissue because each of the four candidate genes and proteins (natriuretic peptide receptor 1 (NPR1), NPR2, NPR3 and membrane metallo-endopeptidase (MME)) are expressed there. DNA samples were genotyped for 120 single nucleotide polymorphisms (SNP) in these four genes using …

Prenatal Genetic Diagnosis Using Transcervically Derived And Immunomagnetically Isolated Trophoblast Cells, Swati Bajpayee

Honors College Theses

Trophoblast cells migrate from the placenta into the endocervical canal early in the first trimester and can be collected non-invasively by transcervical sampling (TCS), potentially providing fetal DNA for prenatal genetic diagnosis. Experiments were conducted to separate fetal cells from maternal cells within the TCS specimens and use the fetal cells to perform genetic analysis. Trophoblast cells were efficiently isolated from TCS specimens during weeks 5-18 of gestation using HLA-G antibody coupled to magnetic nanoparticles. Immunofluorescence microscopy revealed that 99% of isolated cells expressed the chorionic gonadotropin β subunit (β-CG), while the non-bound cell fraction expressed none. Immunomagnetically isolated cells …

The Design And Testing Of A Solar Autoclave With Broad Spectrum Sterilization Capabilities, Sarah S. Trabia

Honors College Theses

Energy is difficult to come by in developing countries and this interferes with the ability of doctors to provide good healthcare to their patients. Without decent sterilization, patients can become infected and diseases can spread throughout hospitals. This study involves designing a solar autoclave for developing countries that is as efficient as electrical autoclaves. The design is intended to not require any electrical input and to be affordable to those who cannot afford advanced medical equipment. Once the solar autoclave is designed, it will be tested to determine if it can sterilize equipment against a variety of different bacteria, including …

The Role Of Micrornas In Breast Cancer Migration, Invasion And Metastasis, Joy Tang, Fazlul H. Sarkar, Aamir Ahmad

Honors College Theses

MicroRNAs (miRNAs) are a major class of small, noncoding RNA molecules that regulate gene expression by targeting mRNAs to trigger either translational repression or mRNA degradation. They have recently been more widely investigated due to their potential role as targets for cancer therapy. Many miRNAs have been implicated in several human cancers, including breast cancer. miRNAs are known to regulate cell cycle and development, and thus may serve as useful targets for exploration in anticancer therapeutics. The link between altered miRNA signatures and breast cancer development and metastasis can be observed either through the loss of tumor suppressor miRNAs, such …